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https://www.readbyqxmd.com/read/28065874/is-complex-sphenoidal-sinus-anatomy-a-contraindication-to-a-transsphenoidal-approach-for-resection-of-sellar-lesions-presentation-of-a-case-series-and-review-of-the-literature
#1
Marco Locatelli, Andrea Di Cristofori, Riccardo Draghi, Giulio Bertani, Claudio Guastella, Lorenzo Pignataro, Giovanna Mantovani, Paolo Rampini, Giorgio Carrabba
BACKGROUND: The transsphenoidal approach (TNS) is considered the gold standard for resection of pituitary adenomas and other sellar region lesions. This approach is guided by few fundamental anatomical landmarks that conduct the surgeon toward the sellar floor. Some anatomical structures may vary a lot (e.g. intrasphenoidal septa, intercarotid distance) and may be difficult to identify. Among those structures, the pneumatization and conformation of the sphenoidal sinus (SS) plays a key role for accessing the floor of the sella and other skull base structures...
January 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28057594/significant-improvement-in-chronic-persistent-headaches-caused-by-small-rathke-cleft-cysts-after-transsphenoidal-surgery
#2
Issei Fukui, Yasuhiko Hayashi, Daisuke Kita, Yasuo Sasagawa, Masahiro Oishi, Osamu Tachibana, Mitsutoshi Nakada
PURPOSE: Rathke cleft cysts (RCC) are usually asymptomatic and can be observed using conservative methods. However, some patients with RCCs have severe headaches even if they are small enough to be confined to the sella, and these small RCCs have seldom been discussed. This study presents an investigation into clinical characteristics of small RCCs associated with severe headaches, demonstrating efficacy and safety of endoscopic transsphenoidal surgery (ETSS) to relieve headaches. METHODS: In this study, 13 patients with small RCCs (maximum diameter < 10mm) who presented with headaches and were treated by ETSS at our institute from 2009 to 2014 were recruited...
January 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28045810/the-protruding-premaxilla-is-our-current-approach-the-right-answer
#3
Katelyn G Bennett, Heather M Hendricks, Todd E Thurston, Steven J Kasten, Christian J Vercler, Steven R Buchman
BACKGROUND: In bilateral cleft patients, surgeons usually attempt to move the premaxillary segment posteriorly. These patients almost always develop maxillary hypoplasia, rendering our current algorithms questionable. The authors sought to determine if the lateral segments are in an appropriate position to serve as a target for movement of the premaxilla. METHODS: Bilateral cleft lip and palate patients treated at the University of Michigan from 1997 to 2015 were reviewed...
December 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28041886/maxillary-advancement-versus-mandibular-setback-in-class-iii-dentofacial-deformity-are-there-any-differences-in-aesthetic-outcomes
#4
M Ghassemi, R-D Hilgers, U Fritz, A Modabber, A Ghassemi
A retrospective evaluation of maxillary advancement and mandibular setback in class III patients was performed and their aesthetic outcomes compared. Patients with a sella-nasion-A-point angle (SNA) of 80-84° were selected. Pre- and postoperative lateral cephalograms were obtained for 34 class III patients; these were divided into two groups according to the surgical procedure performed: mandibular setback group (n=17) and maxillary advancement group (n=17). The pre- and postoperative cervical length, lip-chin-throat angle, lower/upper lip thickness, distance from the lower/upper lip to the aesthetic line, soft tissue angle, facial contour angle, and nasolabial angle of the two groups were compared...
December 29, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28034574/orthodontic-camouflage-versus-orthognathic-surgery-for-class-iii-deformity-comparative-cephalometric-analysis
#5
P Martinez, C Bellot-Arcís, J M Llamas, R Cibrian, J L Gandia, V Paredes-Gallardo
The objective of this study was to compare different cephalometric variables in adult patients with class III malocclusions before and after treatment, in order to determine which variables are indicative of orthodontic camouflage or orthognathic surgery. The cases of 156 adult patients were assessed: 77 treated with orthodontic camouflage and 79 treated with orthodontics and orthognathic surgery. The following cephalometric variables were measured on pre-treatment (T1) and post-treatment (T2) lateral cephalograms: sella-nasion-A-point (SNA), sella-nasion-B-point (SNB), and A-point-nasion-B-point (ANB) angles, Wits appraisal, facial axis angle, mandibular plane angle, upper and lower incisor inclination, and inter-incisal angle...
December 26, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28024764/precision-of-manual-landmark-identification-between-as-received-and-oriented-volume-rendered-cone-beam-computed-tomography-images
#6
Abhishek Gupta, Om Prakash Kharbanda, Rajiv Balachandran, Viren Sardana, Shilpa Kalra, Sushma Chaurasia, Harish Kumar Sardana
INTRODUCTION: The objective of this study was to evaluate the effect of the orientation of cone-beam computed tomography (CBCT) images on the precision and reliability of 3-dimensional cephalometric landmark identification. METHODS: Ten CBCT scans were used for manual landmark identification. Volume-rendered images were oriented by aligning the Frankfort horizontal and transorbital planes horizontally, and the midsagittal plane vertically. A total of 20 CBCT images (10 as-received and 10 oriented) were anonymized, and 3 random sets were generated for manual landmark plotting by 3 expert orthodontists...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28018694/anterior-hypopituitarism-and-treatment-response-in-hunter-syndrome-a-comparison-of-two-patients
#7
Munier A Nour, Paola Luca, David Stephure, Xing-Chang Wei, Aneal Khan
Hypopituitarism is a clinically important diagnosis and has not previously been reported in Hunter syndrome. We contrast two cases with anatomic pituitary anomalies: one with anterior panhypopituitarism and the other with intact pituitary function. Patient 1, a 10-year-old boy with Hunter syndrome, was evaluated for poor growth and an ectopic posterior pituitary gland. Endocrine testing revealed growth hormone (GH) deficiency, secondary adrenal insufficiency, and tertiary hypothyroidism. An improvement in growth velocity with hormone replacement (GH, thyroxine, and corticosteroid) was seen; however, final adult height remained compromised...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28009611/pituitary-adenomas-presenting-as-sinonasal-or-nasopharyngeal-masses-a-case-series-illustrating-potential-diagnostic-pitfalls
#8
Martin D Hyrcza, Shereen Ezzat, Ozgur Mete, Sylvia L Asa
We present a series of nonectopic pituitary adenomas presenting as polypoid sinonasal or nasopharyngeal masses. Thirteen cases diagnosed by biopsies from the nasal cavity, sinuses, or nasopharynx were identified from a series of 1288 surgical pituitary specimens. The patients included 5 men and 8 women ranging from 29 to 69 years of age. The presentations included nasal obstruction (4 cases), headaches (3), visual defects (2), recurrent nose bleeds (1), rhinorrhea (1), sepsis (1), fatigue (1), and hyperthyroidism (1)...
December 22, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28009229/transoral-robotic-surgery-for-sellar-tumors-first-clinical-study
#9
Dorian Chauvet, Stéphane Hans, Antoine Missistrano, Celeste Rebours, Wissame El Bakkouri, Guillaume Lot
OBJECTIVE The aim of this study was to confirm the feasibility of an innovative transoral robotic surgery (TORS), using the da Vinci Surgical System, for patients with sellar tumors. This technique was designed to offer a new minimally invasive approach, without soft-palate splitting, that avoids the rhinological side effects of classic endonasal approaches. METHODS The authors performed a prospective study of TORS in patients with symptomatic sellar tumors. Specific anatomical features were required for inclusion in the study and were determined on the basis of preoperative open-mouth CT scans of the brain...
December 23, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28004764/sheehan-syndrome
#10
Züleyha Karaca, Bashir A Laway, Hatice S Dokmetas, Hulusi Atmaca, Fahrettin Kelestimur
Sheehan syndrome or postpartum hypopituitarism is a condition characterized by hypopituitarism due to necrosis of the pituitary gland. The initial insult is caused by massive postpartum haemorrhage (PPH), leading to impaired blood supply to the pituitary gland, which has become enlarged during pregnancy. Small sella turcica size, vasospasms (caused by PPH) and/or thrombosis (associated with pregnancy or coagulation disorders) are predisposing factors; autoimmunity might be involved in the progressive worsening of pituitary functions...
December 22, 2016: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28003168/endoscopic-endonasal-surgery-for-remission-of-cushing-disease-caused-by-ectopic-intracavernous-macroadenoma-case-report-and-literature-review
#11
Maria Koutourousiou, Welby I Winstead
BACKGROUND: Complete surgical resection of an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma is the gold standard of treatment of Cushing disease. Ectopic location of these adenomas is an extremely rare condition that may compromise the diagnosis and surgical success. We present the first case of an ectopic intracavernous ACTH-secreting macroadenoma totally resected with endoscopic endonasal surgery (EES). CASE DESCRIPTION: A 36-year-old woman presented with Cushing syndrome...
December 18, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27989632/molecular-phylogeny-and-patterns-of-diversification-in-syngnathid-fishes
#12
Healy Hamilton, Norah Saarman, Graham Short, Anna B Sellas, Beth Moore, Tinya Hoang, Christopher L Grace, Martin Gomon, Karen Crow, W Brian Simison
The family Syngnathidae is a large and diverse clade of morphologically unique bony fishes, with 57 genera and 300 described species of seahorses, pipefishes, pipehorses, and seadragons. They primarily inhabit shallow coastal waters in temperate and tropical oceans, and are characterized by a fused jaw, male brooding, and extraordinary crypsis. Phylogenetic relationships within the Syngnathidae remain poorly resolved due to lack of generic taxon sampling, few diagnostic morphological characters, and limited molecular data...
October 29, 2016: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/27967223/visual-vignettes-persistent-headaches-with-apparent-empty-sella-syndrome
#13
Jeyakantha Ratnasingam, Kheng Chiew Chooi, Syahrizan Samsuddin, Sharmila Paramasivam, Luqman Ibrahim, Lee Ling Lim, Alexander Tan, Shireene Vethakkan
No abstract text is available yet for this article.
December 14, 2016: Endocrine Practice
https://www.readbyqxmd.com/read/27931847/mind-the-brain-the-mediating-and-moderating-role-of-neurophysiology
#14
Siobhán Harty, Francesco Sella, Roi Cohen Kadosh
Most studies involving experimental manipulations or interventions tailored to modulate behavior do not account for variability in the critical antecedent of behavior, the brain. Here, we describe elegant approaches to model the role that neurophysiology can play in mediating or moderating relationships in this context. We highlight the capacity for these approaches to improve the inferential power of research, bridge the gap between neural and behavioral levels of analysis, and bolster the prospects for reproducibility...
January 2017: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/27922970/morphometric-analysis-of-sella-turcica-using-cone-beam-computed-tomography
#15
Yasin Yasa, Ali Ocak, Ibrahim Sevki Bayrakdar, Suayip Burak Duman, Ismail Gumussoy
OBJECTIVE: The purpose of this study was to assess morphological shape and morphometric analysis of the sella turcica using cone beam computed tomography (CBCT) in different planes of section (coronal and sagittal). MATERIALS AND METHODS: CBCT images of 177 subjects of which 51 males and 126 females in the age group of 11 to 73 years were included in the study population. Linear dimensions which include the length, depth, diameter, and interclinoid distance were measured and the shape of sella turcica was analyzed...
December 5, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27918153/enlargement-of-meckel-s-cave-in-patients-with-spontaneous-cerebrospinal-fluid-leaks
#16
Geoffrey P Aaron, Elisa Illing, Zachary Lambertsen, Miles Ritter, Erik H Middlebrooks, Joel Cure, Do-Yeon Cho, Kristen O Riley, Bradford A Woodworth
BACKGROUND: Spontaneous cerebrospinal fluid (CSF) leaks have imaging findings consistent with chronically elevated intracranial pressure, such as empty sella. Meckel's cave is a CSF-filled space that houses the trigeminal ganglion at the cranial base. Our objective in this study was to evaluate "dilated" Meckel's cave as a radiologic sign in patients with elevated intracranial pressure spontaneous CSF leaks and compare the dimensions with those from a control cohort. METHODS: Meckel's cave dimensions were measured in patients with spontaneous CSF leaks and documented elevated intracranial pressure...
December 5, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27910768/pharmacological-properties-of-biocompounds-from-spores-of-the-lingzhi-or-reishi-medicinal-mushroom-ganoderma-lucidum-agaricomycetes-a-review
#17
Carlos Ricardo Soccol, Lucas Yamasaki Bissoqui, Cristine Rodrigues, Rosalia Rubel, Sandra R B R Sella, Fan Leifa, Luciana Porto de Souza Vandenberghe, Vanete Thomaz Soccol
Ganoderma lucidum is a well-known representative of mushrooms that have been used in traditional Chinese medicine for centuries. New discoveries related to this medicinal mushroom and its biological properties are frequently reported. However, only recently have scientists started to pay special attention to G. lucidum spores. This is in part because of the recent development of methods for breaking the spore wall and extracting biocompounds from the spore. Although some research groups are working with G. lucidum spores, data in the literature are still limited, and the methods used have not been systematized...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27901326/tuberculuma-sellae-meningiomas-a-systematic-review-of-transcranial-approaches-in-the-endoscopic-era
#18
Mazda Turel, Georgios Tsermoulas, Abdulmounem Yasssin-Kassab, Deven Reddy, Hugo Andrade-Barazarte, Lior Gonen, Gelareh Zadeh, Fred Gentili
INTRODUCTION: With the advent of skull base endoscopy, tuberculum sellae meningiomas (TSMs) are currently operated both from the traditional transcranial (TC) route as well as the extended endonasal endoscopic trasnssphenoidal approach (EETS). The aim of this study was to conduct a systematic review of TSMs excised via the TC route in the modern era when the EETS excision is gaining popularity. EVIDENCE ACQUISITION: We performed a systematic review in the medical literature following the PRISMA guidelines...
November 30, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27890190/imaging-of-the-sella-and-parasellar-region
#19
REVIEW
John L Go, Anandh G Rajamohan
The sella and parasellar region, found between the anterior and central skull base, represents the central aspect of the skull base. Given the location of the pituitary gland in this location, small lesions in this location may have major physiologic effects on the human body. This article reviews the anatomy, development, and pathologic processes that may involve this region.
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27889026/imaging-of-the-sella-and-parasellar-region-in-the-pediatric-population
#20
REVIEW
Daniel P Seeburg, Marjolein H G Dremmen, Thierry A G M Huisman
Masses in the sella and parasellar region comprise about 10% of all pediatric brain tumors but type and frequency differs from those in adults. Imaging is critical for diagnosis and characterization of these lesions. By assessing the site of origin, signal and contrast enhancement characteristics, and the presence or absence of characteristic patterns, differential diagnosis can narrow the possibilities. The clinical presentation is often characteristic for lesion type and should be considered. This article summarizes the characteristic imaging features of the most frequent pediatric tumors and tumor-mimicking lesions in children in this region...
February 2017: Neuroimaging Clinics of North America
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