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Total parenteral nutrition, medical, ICU

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https://www.readbyqxmd.com/read/27230550/nutritional-support-for-critically-ill-children
#1
REVIEW
Ari Joffe, Natalie Anton, Laurance Lequier, Ben Vandermeer, Lisa Tjosvold, Bodil Larsen, Lisa Hartling
BACKGROUND: Nutritional support in the critically ill child has not been well investigated and is a controversial topic within paediatric intensive care. There are no clear guidelines as to the best form or timing of nutrition in critically ill infants and children. This is an update of a review that was originally published in 2009. . OBJECTIVES: The objective of this review was to assess the impact of enteral and parenteral nutrition given in the first week of illness on clinically important outcomes in critically ill children...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26801983/space-glucosecontrol-system-for-blood-glucose-control-in-intensive-care-patients-a-european-multicentre-observational-study
#2
MULTICENTER STUDY
Jan Blaha, Barbara Barteczko-Grajek, Pawel Berezowicz, Jiri Charvat, Jiri Chvojka, Teodoro Grau, Jonathan Holmgren, Ulrich Jaschinski, Petr Kopecky, Jan Manak, Mette Moehl, Jonathan Paddle, Marcello Pasculli, Johan Petersson, Sirak Petros, Danilo Radrizzani, Vinodkumar Singh, Joel Starkopf
BACKGROUND: Glycaemia control (GC) remains an important therapeutic goal in critically ill patients. The enhanced Model Predictive Control (eMPC) algorithm, which models the behaviour of blood glucose (BG) and insulin sensitivity in individual ICU patients with variable blood samples, is an effective, clinically proven computer based protocol successfully tested at multiple institutions on medical and surgical patients with different nutritional protocols. eMPC has been integrated into the B...
January 22, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/26348113/early-enhanced-parenteral-nutrition-hyperglycemia-and-death-among-extremely-low-birth-weight-infants
#3
Hans Jorgen Stensvold, Kenneth Strommen, Astri M Lang, Tore G Abrahamsen, Eline Kjorsvik Steen, Are H Pripp, Arild E Ronnestad
IMPORTANCE: Efforts to optimize early parenteral nutrition (PN) in extremely low-birth-weight (ELBW) infants to promote growth and development may increase hyperglycemia risk. Recent studies have identified an association between early hyperglycemia and adverse outcomes in ELBW infants. OBJECTIVES: To examine the prevalence of early hyperglycemia and clinical outcomes among ELBW infants before (2002-2005) and after (2006-2011) the implementation of an early enhanced PN protocol and to assess the independent effects of early enhanced PN and early hyperglycemia on mortality...
November 2015: JAMA Pediatrics
https://www.readbyqxmd.com/read/25921561/parenteral-nutrition-utilization-after-implementation-of-multidisciplinary-nutrition-support-team-oversight-a-prospective-cohort-study
#4
Brodie Parent, Marilyn Shelton, Megan Nordlund, Shahram Aarabi, Grant O'Keefe
BACKGROUND: Multidisciplinary nutrition teams can help guide the use of parenteral nutrition (PN), thereby reducing infectious risk, morbidity, and associated costs. Starting in 2007 at Harborview Medical Center, weekly multidisciplinary meetings were established to review all patients receiving PN. This study reports on observed changes in utilization from 2005-2010. MATERIALS AND METHODS: All patients who received PN from 2005-2010 were followed prospectively...
November 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/25872170/risk-factors-for-the-development-of-intra-abdominal-fungal-infections-in-acute-pancreatitis
#5
Brian J Schwender, Stuart R Gordon, Timothy B Gardner
OBJECTIVES: Intra-abdominal fungal infections (AFIs) complicating acute pancreatitis arise in the context of pancreatic necrosis. Our goal was to determine which risk factors contribute to AFI in patients with acute pancreatitis. METHODS: Records were reviewed from 479 nontransfer patients admitted to our medical center with acute pancreatitis from 1985 to 2009. Using multivariable regression models, we identified risk factors for AFI. RESULTS: Of 479 patients admitted with acute pancreatitis, 17 patients were subsequently found to have an AFI and 3 of these patients died...
July 2015: Pancreas
https://www.readbyqxmd.com/read/25798955/-patients-treated-with-micafungin-during-their-stay-in-intensive-care-unit
#6
F Álvarez-Lerma, S Grau, C López, J D Jiménez, M V Trasmonte, M Nieto, G Parra, E Herrero
OBJECTIVES: To determine the reasons of prescription, the characteristics of patients and factors that affected the outcome of critically ill patients treated with micafungin (MCF) during their stay in Spanish ICUs. MATERIAL AND METHODS: Observational, retrospective and multicenter study. Patients admitted to the ICU between March 2011 and October 2012 (20-month period) treated with MCF for any reason were included in the study. Severity of patients at the beginning of treatment was measured with the APACHE II, SOFA, Child-Pugh and MELD scores...
November 2015: Medicina Intensiva
https://www.readbyqxmd.com/read/25558635/refeeding-hypophosphatemia-a-potentially-fatal-danger-in-the-intensive-care-unit
#7
Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur
AIM: To determine the overall and comparative incidence of refeeding hypophosphatemia (RH) between enteral and parenteral nutrition in general adult intensive care unit (ICU) patients. MATERIALS AND METHODS: This study was performed as a retrospective analysis. A total of 117 patients who received enteral and parenteral nutrition were included in the study. Demographic characteristics, type of nutrition, daily energy intake, and serum phosphorus levels before and after the initiation of the nutrition were recorded for 7 days...
2014: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/25552161/a-general-consideration-of-the-importance-of-nutrition-for-critically-ill-patients
#8
Ersin Gürkan Dumlu, Mesut Özdedeoğlu, Birkan Bozkurt, Mehmet Tokaç, Abdussamed Yalçin, Levent Öztürk, Mehmet Kiliç
BACKGROUND/AIM: Malnutrition is a common medical condition among intensive care unit patients. It should be monitored carefully, since early management of malnutrition can dramatically improve the medical condition of the patients. A general consideration of enteral feeding shows that it is much more useful than parenteral administration, because it is more physiological and poses a lower risk of hyperalimentation. MATERIALS AND METHODS: In this retrospective study, we scanned all files and personal information of patients hospitalized in intensive care units between 2009 and 2012 due to various medical conditions...
2014: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/25346899/surgical-ligation-on-significant-patent-ductus-arteriosus-in-very-low-birth-weight-infants-comparison-between-early-and-late-ligations
#9
Jun Ho Lee, Sun Kyun Ro, Hyun Ju Lee, Hyun Kyung Park, Won-Sang Chung, Young Hak Kim, Jeong Ho Kang, Hyuck Kim
BACKGROUND: We aimed to evaluate the efficacy and safety of early surgical ligation (within 15 days of age) over late surgical ligation (after 15 days of age) by a comparative analysis of very low birth weight (VLBW) infants undergoing surgical correction for symptomatic patent ductus arteriosus (PDA) over the course of 6 years in our hospital. METHODS: We retrospectively reviewed all the medical records in the neonatal intensive care unit at Hanyang University Seoul Hospital, from March 2007 to May 2013, to identify VLBW infants (< 1,500 g) who underwent surgical PDA ligation...
October 2014: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/25306190/minimizing-the-risk-of-preoperative-brain-injury-in-neonates-with-aortic-arch-obstruction
#10
MULTICENTER STUDY
Selma O Algra, Felix Haas, Kenneth J Poskitt, Floris Groenendaal, Antonius N J Schouten, Nicolaas J G Jansen, Anthony Azakie, Sanjiv Gandhi, Andrew Campbell, Steven P Miller, Patrick S McQuillen, Linda S de Vries
OBJECTIVE: To determine whether prenatal diagnosis lowers the risk of preoperative brain injury by assessing differences in the incidence of preoperative brain injury across centers. STUDY DESIGN: From 2 prospective cohorts of newborns with complex congenital heart disease studied by preoperative cerebral magnetic resonance imaging, one cohort from the University Medical Center Utrecht (UMCU) and a combined cohort from the University of California San Francisco (UCSF) and University of British Columbia (UBC), patients with aortic arch obstruction were selected and their imaging and clinical course reviewed...
December 2014: Journal of Pediatrics
https://www.readbyqxmd.com/read/25276681/factors-affecting-the-neonatal-intensive-care-unit-stay-duration-in-very-low-birth-weight-premature-infants
#11
Akram Niknajad, Morteza Ghojazadeh, Niloufar Sattarzadeh, Fazileh Bashar Hashemi, Farid Dezham Khoy Shahgholi
INTRODUCTION: Improved survival of very low birth weight (VLBW) premature infants requires urgent intensive care, professional nursing and medical care. On the other hand, long hospital stay period imposes emotional and economic burdens on the family and society. Therefore, it is necessary to clarify the most important factors affecting their hospitalization duration to lessen unwanted outcomes of premature birth and to eliminate or relieve the problems. METHODS: In a descriptive-analytical study, 170 low birth weight premature infants were assessed in a regular daily follow-up in Alzahra Hospital, Tabriz, Iran...
June 2012: Journal of Caring Sciences
https://www.readbyqxmd.com/read/25253364/total-parenteral-nutrition-associated-cholestasis-and-risk-factors-in-preterm-infants
#12
Turki M Alkharfy, Rubana Ba-Abbad, Anjum Hadi, Badr H Sobaih, Khalid M AlFaleh
BACKGROUND/AIM: Development of hepatic dysfunction is a well-recognized complication of total parenteral nutrition in preterm infants. Previous studies reported the incidence of total parenteral nutrition-associated cholestasis and described possible contributing factors to its pathogenesis, but little is done trying to determine its possible predictive risk factors. The aims of this study was to determine the incidence of total parenteral nutrition-associated cholestasis and to develop a possible predictive model for its occurrence...
September 2014: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/25248359/quality-and-safety-impact-on-the-provision-of-parenteral-nutrition-through-introduction-of-a-nutrition-support-team
#13
C L Hvas, K Farrer, E Donaldson, B Blackett, H Lloyd, C Forde, G Garside, P Paine, S Lal
BACKGROUND/OBJECTIVES: Parenteral nutrition (PN) should be provided to the malnourished patient if enteral feeding is insufficient or unsafe. A nutrition support team (NST) may improve PN services. We compared the use and complications of hospital PN before and after the implementation of an NST. SUBJECTS/METHODS: All inpatients referred for PN outside of the intensive care unit and the intestinal failure unit were prospectively included from 2009 to 2012. The NST was introduced in 2010...
December 2014: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/25226273/influence-of-n-3-polyunsaturated-fatty-acids-enriched-lipid-emulsions-on-nosocomial-infections-and-clinical-outcomes-in-critically-ill-patients-icu-lipids-study
#14
RANDOMIZED CONTROLLED TRIAL
Teodoro Grau-Carmona, Alfonso Bonet-Saris, Abelardo García-de-Lorenzo, Carmen Sánchez-Alvarez, Angel Rodríguez-Pozo, José Acosta-Escribano, Eduardo Miñambres, Jose Ignacio Herrero-Meseguer, Alfonso Mesejo
OBJECTIVE: n-3 polyunsaturated fatty acids (contained in fish oil) have been shown to beneficially influence infection rate and clinical outcomes in surgical patients probably due to their immunomodulatory action. In contrast, study results of fish oil administration in critically ill patients are controversial. The aim of this study was to investigate the effects of n-3 polyunsaturated fatty acids on the prevalence of nosocomial infections and clinical outcomes in medical and surgical critically ill patients...
January 2015: Critical Care Medicine
https://www.readbyqxmd.com/read/25215012/protective-effect-of-glutamine-in-critical-patients-with-acute-liver-injury
#15
Hai-Bin Ni, Zheng Zhang, Hai-Dong Qin
BACKGROUND: Glutamine (Gln) supplementation is known to decrease oxidative stress and inflammatory response, enhance resistance to infectious pathogens, shorten hospital stay, and decrease medical costs of patients. This study was undertaken to evaluate the relationship between the effect of early parenteral glutamine (Gln) supplement on acute liver injury (ALI) and heat shock protein 70 (HSP-70) expression in critical patients. METHODS: Forty-four patients who had been admitted to the emergency intensive care unit (EICU) of Nanjing First Hospital Affiliated to Nanjing Medical University were randomly divided into a control group (n=22) and a Gln group (n=22)...
2011: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/25058748/standardizing-morphine-use-for-ventilated-preterm-neonates-with-a-nursing-driven-comfort-protocol
#16
R Fleishman, C Zhou, C Gleason, C Larison, M T Myaing, R Mangione-Smith
OBJECTIVE: To test whether implementing a nursing-driven comfort protocol standardizes morphine use in one neonatal intensive care unit (NICU) and to examine how non-standard morphine (N-SM) relates to days of ventilation, days of total parenteral nutrition (TPN) and length of stay (LOS). STUDY DESIGN: This was a retrospective/prospective observational study using pharmacy records, medical records, and an outcomes database. Comfort protocol implementation began February 2011 and was applied to preterm, ventilated neonates <1500 grams...
January 2015: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/24881132/lessons-from-emergency-laparotomy-for-abdominal-tuberculosis-in-the-hiv-aids-era
#17
J Islam, D L Clarke, S R Thomson
BACKGROUND: The rising incidence of HIV/AIDS has resulted in a resurgence of abdominal tuberculosis (TB) in HIV-positive patients in South Africa. These often debilitated patients frequently present with acute complications requiring surgery. METHODS: A prospective audit of all patients with abdominal TB undergoing emergency laparotomy was conducted. From January 2008 to June 2010, 49 patients had emergency laparotomy and specimens obtained from them were diagnostic of TB...
February 2014: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/24792864/timing-of-ostomy-reversal-in-neonates-with-necrotizing-enterocolitis
#18
Michelle Veenstra, Kartheek Nagappala, Logan Danielson, Michael Klein
INTRODUCTION: Most neonates with necrotizing enterocolitis (NEC) requiring laparotomy have bowel resection and intestinal diversion. At present, there is no consensus regarding the best time for enterostomy reversal. Our aim is to determine if there is any difference in outcomes of infants whose enterostomy was reversed early versus late. MATERIALS AND METHODS: We retrospectively reviewed medical records of patients with NEC admitted to the neonatal intensive care unit at a large urban children's hospital from 2002 to 2010...
June 2015: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/24690614/evaluating-the-significance-of-delaying-intravenous-lipid-therapy-during-the-first-week-of-hospitalization-in-the-intensive-care-unit
#19
Janet Arrazcaeta, Stephen Lemon
BACKGROUND: The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) and the Society of Critical Care Medicine (SCCM) published guidelines in 2009 recommending against the use of intravenous lipids for parenteral nutrition (PN) within the first week of hospitalization in critically ill patients. This grade D recommendation is controversial as it is based on the results of 2 studies that evaluated approximately 100 patients and did not evaluate glycemic control. The purpose of this study was to evaluate outcomes associated with the receipt of lipids within the first week in the intensive care unit (ICU) compared with withholding lipids...
June 2014: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/24478944/development-of-clinical-pharmacy-services-for-intensive-care-units-in-korea
#20
Jeong Mee Kim, So Jin Park, You Min Sohn, Young Mee Lee, Catherine Seonghee Yang, Hye Sun Gwak, Byung Koo Lee
OBJECTIVE: To be utilized for the development of pharmacists' intervention service by determining factors which affect pharmacists' prescription interventions. SETTING: Patients who were admitted to intensive care units (ICUs) in internal medicine departments in Korea. METHODS: Data including age, gender, clinical departments, length of hospital stay, status of organ dysfunction, intervention status, frequently intervened drugs, and health care providers' questions were prospectively collected in ICUs in the department of internal medicine in a tertiary teaching hospital from January to December, 2012...
2014: SpringerPlus
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