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https://www.readbyqxmd.com/read/29214896/outcome-evaluation-on-cochlear-implant-users-with-residual-hearing
#1
Nicole Neben, Andreas Buechner, Mark Schuessler, Thomas Lenarz
OBJECTIVES: The performance outcome with Freedom™ Hybrid™ versus the CP900 series sound processor with Hybrid Hearing was investigated. In addition, a preliminary evaluation was conducted to consider the feasibility of upgrading experienced electric-only cochlear implant (CI) users who had substantial residual hearing to Hybrid Hearing. METHODS: This study was a single-centre prospective, non-inferiority design with repeated measures conducted at Hannover Medical School (MHH)...
December 7, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/29182495/platelet-transfusion-for-patients-with-cancer-american-society-of-clinical-oncology-clinical-practice-guideline-update
#2
Charles A Schiffer, Kari Bohlke, Meghan Delaney, Heather Hume, Anthony J Magdalinski, Jeffrey J McCullough, James L Omel, John M Rainey, Paolo Rebulla, Scott D Rowley, Michael B Troner, Kenneth C Anderson
Purpose To provide evidence-based guidance on the use of platelet transfusion in people with cancer. This guideline updates and replaces the previous ASCO platelet transfusion guideline published initially in 2001. Methods ASCO convened an Expert Panel and conducted a systematic review of the medical literature published from September 1, 2014, through October 26, 2016. This review builds on two 2015 systematic reviews that were conducted by the AABB and the International Collaboration for Transfusion Medicine Guidelines...
November 28, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29153348/sampling-methods-to-the-statistical-control-of-the-production-of-blood-components
#3
REVIEW
Paulo Pereira, Jerard Seghatchian, Beatriz Caldeira, Paula Santos, Rosa Castro, Teresa Fernandes, Sandra Xavier, Gracinda de Sousa, João Paulo de Almeida E Sousa
The control of blood components specifications is a requirement generalized in Europe by the European Commission Directives and in the US by the AABB standards. The use of a statistical process control methodology is recommended in the related literature, including the EDQM guideline. The control reliability is dependent of the sampling. However, a correct sampling methodology seems not to be systematically applied. Commonly, the sampling is intended to comply uniquely with the 1% specification to the produced blood components...
November 8, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29078757/transposable-elements-generate-population-specific-insertional-patterns-and-allelic-variation-in-genes-of-wild-emmer-wheat-triticum-turgidum-ssp-dicoccoides
#4
Katherine Domb, Danielle Keidar, Beery Yaakov, Vadim Khasdan, Khalil Kashkush
BACKGROUND: Natural populations of the tetraploid wild emmer wheat (genome AABB) were previously shown to demonstrate eco-geographically structured genetic and epigenetic diversity. Transposable elements (TEs) might make up a significant part of the genetic and epigenetic variation between individuals and populations because they comprise over 80% of the wild emmer wheat genome. In this study, we performed detailed analyses to assess the dynamics of transposable elements in 50 accessions of wild emmer wheat collected from 5 geographically isolated sites...
October 27, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29075271/identification-of-qtl-for-grain-size-and-shape-on-the-d-genome-of-natural-and-synthetic-allohexaploid-wheats-with-near-identical-aabb-genomes
#5
Lei Yan, Fei Liang, Huanwen Xu, Xiaoping Zhang, Huijie Zhai, Qixin Sun, Zhongfu Ni
Grain size and shape associated with yield and milling quality are important traits in wheat domestication and breeding. To reveal the genetic factors on the D genome that control grain size and shape variation, we conducted analysis of quantitative trait loci (QTL) using the F2 and F2:3 populations derived from a common allohexaploid wheat line TAA10 and a synthetic allohexaploid wheat XX329, which have near-identical AABB genomes and different DD genomes. Based on genotyping using wheat 660K single nucleotide polymorphism (SNP) array, TAA10 and XX329 exhibited 96...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29071747/the-management-of-anticoagulation-in-patients-undergoing-therapeutic-plasma-exchange-a-concise-review
#6
REVIEW
Sara M Shunkwiler, Huy P Pham, Geoffrey Wool, Tina S Ipe, Deanna C Fang, Elizabeth Biller, Angela Treml, John Weiss, Beverly W Baron, Mary Berg
We surveyed multiple apheresis centers represented by the authors for their clinical approach to the management of anticoagulation issues during therapeutic plasma exchange (TPE). We present the results of their practices and a review of the pertinent literature. As plasma is removed during TPE, replacement with all or partial non-plasma-containing fluids (eg, 5% albumin) may lead to significant changes in hemostasis. These changes are amplified in patients who are receiving anticoagulation. We discuss various anticoagulants as well as the monitoring and adjustment of anticoagulation before, during, and after TPE...
October 26, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/29047547/electrically-tunable-all-optical-diode-in-a-one-dimensional-photonic-crystal-structure
#7
Kazem Jamshidi-Ghaleh, Fatemeh Moslemi
All-optical-diode tunability with externally applied voltage in a one-dimensional photonic crystal structure of arrangement (BA)(5)/AgLiNbO3Ag/(AB)(5)(AABB)(5) was investigated. It is an asymmetric hybrid Fabry-Perot resonator which is composed of distributed Bragg reflector segments (AB(5)) containing the linear (B layers) and nonlinear (A layers) optical materials. The LiNbO3, (LNO) sandwiched with two pairs Ag layers, is employed as a defect. The electro-optical (EO) effect and optical nonlinear response (Kerr effect) of LNO is considered...
May 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29020918/hox-genes-reveal-genomic-dna-variation-in-tetraploid-hybrids-derived-from-carassius-auratus-red-var-female-%C3%A3-megalobrama-amblycephala-male
#8
Y D Wang, Q B Qin, R Yang, W Z Sun, Q W Liu, Y Y Huo, X Huang, M Tao, C Zhang, T Li, S J Liu
BACKGROUND: Allotetraploid F1 hybrids (4nF1) (AABB, 4n = 148) were generated from the distant hybridization of Carassius auratus red var. (RCC) (AA, 2n = 100) (♀) × Megalobrama amblycephala (BSB) (BB, 2n = 48) (♂). It has been reported that Hox gene clusters are highly conserved among plants and vertebrates. In this study, we investigated the genomic organization of Hox gene clusters in the allotetraploid F1 hybrids and their parents to investigate the polyploidization process. RESULTS: There were three copies of Hox genes in the 4nF1 hybrids, two copies in RCC and one copy in BSB...
October 11, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28948604/transfusion-related-acute-lung-injury-risk-mitigation-an-update
#9
REVIEW
Z K Otrock, C Liu, B J Grossman
Transfusion-related acute lung injury (TRALI) is a life-threatening complication of transfusion. Greater understanding of the pathophysiology of this syndrome has much improved during the last two decades. Plasma-containing components from female donors with leucocyte antibodies were responsible for the majority of TRALI fatalities before mitigation strategies were implemented. Over the past 15 years, measures to mitigate risk for TRALI have been implemented worldwide and they continued to evolve with time...
November 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/28880362/cold-platelets-for-trauma-associated-bleeding-regulatory-approval-accreditation-approval-and-practice-implementation-just-the-tip-of-the-iceberg
#10
James R Stubbs, Sheryl A Tran, Richard L Emery, Scott A Hammel, De Anna L Haugen, Martin D Zielinski, Scott P Zietlow, Donald Jenkins
BACKGROUND: Laboratory and clinical evidence suggest that cold-stored platelets (CS-PLTs) might be preferable to room temperature platelets (RT-PLTs) for active bleeding. Ease of prehospital use plus potential hemostatic superiority led our facility to pursue approval of CS-PLTs for actively bleeding trauma patients. STUDY DESIGN AND METHODS: From November 18, 2013, through October 8, 2015, correspondence was exchanged between our facility, the AABB, and the US Food and Drug Administration (FDA)...
September 6, 2017: Transfusion
https://www.readbyqxmd.com/read/28868734/a-supplement-to-transfusion-abstract-presentations-from-the-aabb-annual-meeting-san-diego-ca-october-7-10-2017
#11
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Transfusion
https://www.readbyqxmd.com/read/28530670/transfusion-practices-for-bone-marrow-harvests-a-survey-analysis-from-the-aabb-bone-marrow-quality-improvement-initiative-working-group
#12
T R Spitzer, M W Sugrue, C Gonzalez, P O'Donnell, D Confer, E Fuchs, M A Pulsipher, J Schwartz, M Linenberger
No abstract text is available yet for this article.
August 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28448637/45s-rdna-external-transcribed-spacer-organization-reveals-new-phylogenetic-relationships-in-avena-genus
#13
Joana Rodrigues, Wanda Viegas, Manuela Silva
The genus Avena comprises four distinct genomes organized in diploid (AA or CC), tetraploid (AABB or AACC) and hexaploid species (AACCDD), constituting an interesting model for phylogenetic analysis. The aim of this work was to characterize 45S rDNA intergenic spacer (IGS) variability in distinct species representative of Avena genome diversity-A. strigosa (AA), A. ventricosa (CvCv), A. eriantha (CpCp), A. barbata (AABB), A. murphyi (AACC), A. sativa (AACCDD) and A. sterilis (AACCDD) through the assessment of the 5' external transcribed spacer (5'-ETS), a promising IGS region for phylogenetic studies poorly studied in Avena genus...
2017: PloS One
https://www.readbyqxmd.com/read/28423007/recombinants-from-the-crosses-between-amphidiploid-and-cultivated-peanut-arachis-hypogaea-for-pest-resistance-breeding-programs
#14
Ailton Ferreira de Paula, Naiana Barbosa Dinato, Bianca Baccili Zanotto Vigna, Alessandra Pereira Fávero
Peanut is a major oilseed crop worldwide. In the Brazilian peanut production, silvering thrips and red necked peanut worm are the most threatening pests. Resistant varieties are considered an alternative to pest control. Many wild diploid Arachis species have shown resistance to these pests, and these can be used in peanut breeding by obtaining hybrid of A and B genomes and subsequent polyploidization with colchicine, resulting in an AABB amphidiploid. This amphidiploid can be crossed with cultivated peanut (AABB) to provide genes of interest to the cultivar...
2017: PloS One
https://www.readbyqxmd.com/read/28370131/use-of-allogeneic-apheresis-stem-cell-products-as-an-interlaboratory-proficiency-challenge
#15
Laura Cooling, Kelly Roxbury, Sandra Hoffmann, Joan DeBusscher, Usha Kota, Steven Goldstein, Robertson Davenport
BACKGROUND: AABB Standards requires that laboratories participate in a proficiency test (PT) program for critical analytes. Institutions can purchase commercial PT materials; however, PT can also be performed through interlaboratory exchange. We investigated the utility of allogeneic hematopoietic progenitor cell apheresis (HPC-A) products as an interlaboratory PT challenge for total nucleated cell count (TNC) and CD34 assessment. STUDY DESIGN AND METHODS: Three-year retrospective and comparative review of unrelated allogeneic HPC-A products received by the University of Michigan between January 2011 and December 2013...
June 2017: Transfusion
https://www.readbyqxmd.com/read/28250587/bread-wheat-progenitors-aegilops-tauschii-dd-genome-and-triticum-dicoccoides-aabb-genome-reveal-differential-antioxidative-response-under-water-stress
#16
Yadhu Suneja, Anil Kumar Gupta, Navtej Singh Bains
Antioxidant enzymes are known to play a significant role in scavenging reactive oxygen species and maintaining cellular homeostasis. Activity of four antioxidant enzymes viz., superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX) and glutathione reductase (GR) was examined in the flag leaves of nine Aegilops tauschii and three Triticum dicoccoides accessions along with two bread wheat cultivars under irrigated and rain-fed conditions. These accessions were shortlisted from a larger set on the basis of field performance for a set of morpho-physiological traits...
January 2017: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/28243829/meiotic-pairing-as-an-indicator-of-genome-composition-in-polyploid-prairie-cordgrass-spartina-pectinata-link
#17
Jeffrey W Bishop, Sumin Kim, María B Villamil, D K Lee, A Lane Rayburn
The existence of neopolyploidy in prairie cordgrass (Spartina pectinata Link) has been documented. The neohexaploid was discovered coexisting with tetraploids in central Illinois, and has been reported to exhibit competitiveness in the natural environment. It is hypothesized that the natural tetraploid cytotype produced the hexaploid cytotype via production of unreduced gametes. Meiosis I chromosome pairing was observed in tetraploid (2n = 4x = 40), hexaploid (2n = 6x = 60), and octoploid (2n = 8x = 80) accessions and the percentage of meiotic abnormality was determined...
April 2017: Genetica
https://www.readbyqxmd.com/read/28043867/bont-ab-hybrid-maintains-similar-duration-of-paresis-as-bont-a-wild-type-in-murine-running-wheel-assay
#18
Anna Kutschenko, Marie-Christine Reinert, Nadja Krez, David Liebetanz, Andreas Rummel
The highly potent Botulinum neurotoxins (BoNT) are successful drugs to treat neuromuscular disorders. Efforts are being made to further reduce the injected BoNT dose and to lengthen the interval between treatments. Detailed knowledge of the BoNT structure-activity relationship (SAR) allows combining the best features of the different BoNT serotypes. Of all seven BoNT serotypes A-G, BoNT/A displays the highest potency despite low neuronal binding affinity, while BoNT/B exhibits much higher affinity. Recently, a new BoNT/AB hybrid (AABB) was constructed comprising the catalytic and translocation domain of BoNT/A and the 50kDa cell binding domain of BoNT/B...
December 30, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27958362/aggregation-and-gelation-of-aromatic-polyamides-with-parallel-and-anti-parallel-alignment-of-molecular-dipole-along-the-backbone
#19
Dan Zhu, Jing Shang, Xiaodong Ye, Jian Shen
The understanding of macromolecular structures and interactions is important but difficult, due to the facts that a macromolecules are of versatile conformations and aggregate states, which vary with environmental conditions and histories. In this work two polyamides with parallel or anti-parallel dipoles along the linear backbone, named as ABAB (parallel) and AABB (anti-parallel) have been studied. By using a combination of methods, the phase behaviors of the polymers during the aggregate and gelation, i.e...
December 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27870740/patient-blood-management-an-international-perspective
#20
MULTICENTER STUDY
Quentin Eichbaum, Michael Murphy, Yu Liu, Isaac Kajja, Ludhmila Abrahao Hajjar, Cees Th Smit Sibinga, Hua Shan
This article describes practices in patient blood management (PBM) in 4 countries on different continents that may provide insights for anesthesiologists and other physicians working in global settings. The article has its foundation in the proceedings of a session at the 2014 AABB annual meeting during which international experts from England, Uganda, China, and Brazil presented the programs and implementation strategies in PBM developed in their respective countries. To systematize the review and enhance the comparability between these countries on different continents, authors were requested to respond to the same set of 6 key questions with respect to their country's PBM program(s)...
December 2016: Anesthesia and Analgesia
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