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https://www.readbyqxmd.com/read/29624677/logistical-and-safety-implications-of-temperature-based-acceptance-of-returned-red-blood-cell-units
#1
Robert A DeSimone, Michael D Nowak, Dian T Lo, Kathleen M Crowley, Priscilla Parra, Melissa M Cushing, Yen-Michael S Hsu
BACKGROUND: AABB requires that red blood cells (RBCs) are maintained at 1 to 10°C during transport. Historically, blood banks used the 30-minute rule for returned RBCs transported outside of validated containers. The implications of this policy have not been previously reported in a real-life hospital setting. STUDY DESIGN AND METHODS: A 2-year, retrospective review of RBC units returned outside of qualified containers was conducted. During the first year, the 30-minute rule was used to accept RBCs back into inventory...
April 6, 2018: Transfusion
https://www.readbyqxmd.com/read/29606089/itraq-based-quantitative-proteomic-analysis-reveals-the-lateral-meristem-developmental-mechanism-for-branched-spike-development-in-tetraploid-wheat-triticum-turgidum-l
#2
Shulin Chen, Juan Chen, Fu Hou, Yigao Feng, Ruiqi Zhang
BACKGROUND: Spike architecture mutants in tetraploid wheat (Triticum turgidum L., 2n = 28, AABB) have a distinct morphology, with parts of the rachis node producing lateral meristems that develop into ramified spikelete (RSs) or four-rowed spikelete (FRSs). The genetic basis of RSs and FRSs has been analyzed, but little is known about the underlying developmental mechanisms of the lateral meristem. We used isobaric tags for relative and absolute quantitation (iTRAQ) to perform a quantitative proteomic analysis of immature spikes harvested from tetraploid near-isogenic lines of wheat with normal spikelete (NSs), FRSs, and RSs and investigated the molecular mechanisms of lateral meristem differentiation and development...
April 2, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29588828/the-effects-of-health-promotion-model-based-educational-program-on-self-care-behaviors-in-patients-undergoing-coronary-artery-bypass-grafting-in-iran
#3
Hossein Mohsenipouya, Fereshteh Majlessi, Abbas Rahimi Forooshani, Rahman Ghafari
Background and aim: Post-operative self-care behaviors, have positive effects on increase in adaptability, and reduce cardiac surgery patients' disability. The present study is carried out aimed at determining the effect of education based on a health promotion model on the patients' self-care behaviors after coronary artery bypass surgery. Methods: This is a semi-experimental study carried out in Mazandaran (Iran) in 2016. Two hundred and twenty patients who participated in the study were selected using a simple random sampling method from a population of postoperative patients, and divided into control and experimental groups (110 patients in each) using block (AABB) randomization...
January 2018: Electronic Physician
https://www.readbyqxmd.com/read/29561440/lower-hemoglobin-transfusion-trigger-is-associated-with-higher-mortality-in-patients-hospitalized-with-pneumonia
#4
Naomi Rahimi-Levene, Maya Koren-Michowitz, Ronit Zeidenstein, Victoria Peer, Ahuva Golik, Tomer Ziv-Baran
Patients hospitalized with pneumonia may require packed red blood cell (RBC) transfusion during their hospital stay. Patient survival may be associated with the transfusion trigger. These patients may need a higher hemoglobin (Hb) trigger than that suggested by the AABB guidelines (7 g/dL).The objective of this study was to evaluate the association between the initial transfusion Hb trigger and in-hospital mortality.A historical cohort study of all patients hospitalized in an internal medicine ward between 2009 and 2014 with pneumonia, who received at least 1 unit of RBC, was evaluated...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29558122/changes-of-seed-weight-fatty-acid-composition-oil-and-protein-content-from-different-peanut-fad2-genotypes-at-different-seed-developmental-and-maturation-stages
#5
Ming Li Wang, Charles Y Chen, Brandon Tonnis, David Pinnow, Jerry Davis, Y Q An, Phat Dang
The level of oleic acid in peanut seed is one of the most important factors in determining seed quality and is controlled by two pairs of homeologous genes (FAD2A and FAD2B). The genotypes of eight F8 breeding lines were determined as AABB, aaBB, AAbb, and aabb by real-time PCR and sequencing. Fresh seeds were collected from five seed developmental stages and, after drying, were used for chemical analysis. Our results showed (1) as seeds developed, seed weight, oil content, and oleic acid level significantly increased, whereas four other fatty acid levels decreased, but protein content and another four fatty acid levels did not significantly change...
March 20, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29520794/critical-developments-of-2017-a-review-of-the-literature-from-selected-topics-in-transfusion-a-committee-report-from-the-aabb-clinical-transfusion-medicine-committee
#6
Melissa M Cushing, James Kelley, Ellen Klapper, David F Friedman, Ruchika Goel, Nancy M Heddle, Courtney K Hopkins, Julie Katz Karp, Monica B Pagano, Ajay Perumbeti, Glenn Ramsey, John D Roback, Joseph Schwartz, Beth H Shaz, Philip C Spinella, Claudia S Cohn, Claudia S Cohn, Melissa M Cushing, James Kelley, Ellen Klapper
BACKGROUND: The AABB compiles an annual synopsis of the published literature covering important developments in the field of Transfusion Medicine. For the first time, an abridged version of this work is being made available in TRANSFUSION, with the full-length report available as an Appendix S1 (available as supporting information in the online version of this paper). STUDY DESIGN AND METHODS: Papers published in 2016 and early 2017 are included, as well as earlier papers cited for background...
March 9, 2018: Transfusion
https://www.readbyqxmd.com/read/29517973/molecular-immunohaematology-round-table-discussions-at-the-aabb-annual-meeting-orlando-2016
#7
Willy A Flegel, Qing Chen, Lilian Castilho, Margaret A Keller, Ellen B Klapper, William J Lane, France Pirenne, Gary Stack, Maryse St-Louis, Christopher A Tormey, Dan A Waxman, Christof Weinstock, Silvano Wendel, Gregory A Denomme
No abstract text is available yet for this article.
February 14, 2018: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/29479708/hemostatic-profile-and-safety-of-pooled-cryoprecipitate-up-to-120-hours-after-thawing
#8
Parvez M Lokhandwala, Adrian O'Neal, Eshan U Patel, Patricia A R Brunker, Eric A Gehrie, Gang Zheng, Thomas S Kickler, Paul M Ness, Aaron A R Tobian
BACKGROUND: AABB standards state that cryoprecipitate should be transfused within 4 to 6 hours after thawing. We evaluated coagulation factor levels and sterility of thawed pooled cryoprecipitate to assess whether shelf life can be safely extended. STUDY DESIGN AND METHODS: Donor cryoprecipitate pools (n = 20, 10 group A, 10 group O) were held at ambient temperature and sampled at 0, 4, 8, 24, 48, 72, 96, and 120 hours post-thawing for fibrinogen, Factor (F)VIII, and von Willebrand factor (vWF) levels...
February 25, 2018: Transfusion
https://www.readbyqxmd.com/read/29467793/decomposing-additive-genetic-variance-revealed-novel-insights-into-trait-evolution-in-synthetic-hexaploid-wheat
#9
Abdulqader Jighly, Reem Joukhadar, Sukhwinder Singh, Francis C Ogbonnaya
Whole genome duplication (WGD) is an evolutionary phenomenon, which causes significant changes to genomic structure and trait architecture. In recent years, a number of studies decomposed the additive genetic variance explained by different sets of variants. However, they investigated diploid populations only and none of the studies examined any polyploid organism. In this research, we extended the application of this approach to polyploids, to differentiate the additive variance explained by the three subgenomes and seven sets of homoeologous chromosomes in synthetic allohexaploid wheat (SHW) to gain a better understanding of trait evolution after WGD...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29402221/transcriptome-analysis-reveals-potential-mechanisms-for-different-grain-size-between-natural-and-resynthesized-allohexaploid-wheats-with-near-identical-aabb-genomes
#10
Lei Yan, Zhenshan Liu, Huanwen Xu, Xiaoping Zhang, Aiju Zhao, Fei Liang, Mingming Xin, Huiru Peng, Yingyin Yao, Qixin Sun, Zhongfu Ni
BACKGROUND: Common wheat is a typical allohexaploid species (AABBDD) derived from the interspecific crossing between allotetraploid wheat (AABB) and Aegilops tauschii (DD). Wide variation in grain size and shape observed among Aegilops tauschii can be retained in synthetic allohexaploid wheats, but the underlying mechanism remains enigmatic. Here, the natural and resynthesized allohexaploid wheats with near-identical AB genomes and different D genomes (TAA10 and XX329) were employed for analysis...
February 5, 2018: BMC Plant Biology
https://www.readbyqxmd.com/read/29332316/how-do-i-implement-a-whole-blood-program-for-massively-bleeding-patients
#11
Mark H Yazer, Andrew P Cap, Philip C Spinella, Louis Alarcon, Darrell J Triulzi
Building on the successful military experience, interest has been rekindled in transfusing whole blood (WB) early in the resuscitation of traumatically injured civilians, often before their ABO group is known. WB efficiently provides treatment for shock and coagulopathy, as well as platelet hemostatic function, to patients losing large volumes of blood. Unlike group O uncrossmatched red blood cells (RBCs), group O WB contains a substantial amount of plasma, which is incompatible with the RBCs of all non-group O recipients...
March 2018: Transfusion
https://www.readbyqxmd.com/read/29287058/activities-of-the-thor-aabb-working-party
#12
Mark H Yazer, Philip C Spinella
The AABB (formerly the American Association of Blood Banks) is an international authority on transfusion medicine and tissue banking. The Trauma, Hemostasis and Oxygenation Research (THOR) Network is an international multidisciplinary network of civilian and military providers ranging from first responders and medics to critical care physicians, and from basic scientists to clinical trialists. The THOR Network's vision is to improve outcomes from traumatic hemorrhagic shock by optimizing the acute phase of resuscitation...
December 28, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29251646/use-of-uncrossmatched-erythrocytes-in-emergency-bleeding-situations
#13
Mark H Yazer, Jonathan H Waters, Philip C Spinella, Col Andrew Cap, Capt Roland L Fahie, Emmett Gourdine, Donald H Jenkins, Steven Kleinman, Ernest E Moore, Paul Ness, Eilat Shinar, Steve R Sloan, James R Stubbs, Kevin R Ward
No abstract text is available yet for this article.
March 2018: Anesthesiology
https://www.readbyqxmd.com/read/29214896/outcome-evaluation-on-cochlear-implant-users-with-residual-hearing
#14
Nicole Neben, Andreas Buechner, Mark Schuessler, Thomas Lenarz
OBJECTIVES: The performance outcome with Freedom™ Hybrid™ versus the CP900 series sound processor with Hybrid Hearing was investigated. In addition, a preliminary evaluation was conducted to consider the feasibility of upgrading experienced electric-only cochlear implant (CI) users who had substantial residual hearing to Hybrid Hearing. METHODS: This study was a single-centre prospective, non-inferiority design with repeated measures conducted at Hannover Medical School (MHH)...
March 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29182495/platelet-transfusion-for-patients-with-cancer-american-society-of-clinical-oncology-clinical-practice-guideline-update
#15
Charles A Schiffer, Kari Bohlke, Meghan Delaney, Heather Hume, Anthony J Magdalinski, Jeffrey J McCullough, James L Omel, John M Rainey, Paolo Rebulla, Scott D Rowley, Michael B Troner, Kenneth C Anderson
Purpose To provide evidence-based guidance on the use of platelet transfusion in people with cancer. This guideline updates and replaces the previous ASCO platelet transfusion guideline published initially in 2001. Methods ASCO convened an Expert Panel and conducted a systematic review of the medical literature published from September 1, 2014, through October 26, 2016. This review builds on two 2015 systematic reviews that were conducted by the AABB and the International Collaboration for Transfusion Medicine Guidelines...
January 20, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29153348/sampling-methods-to-the-statistical-control-of-the-production-of-blood-components
#16
REVIEW
Paulo Pereira, Jerard Seghatchian, Beatriz Caldeira, Paula Santos, Rosa Castro, Teresa Fernandes, Sandra Xavier, Gracinda de Sousa, João Paulo de Almeida E Sousa
The control of blood components specifications is a requirement generalized in Europe by the European Commission Directives and in the US by the AABB standards. The use of a statistical process control methodology is recommended in the related literature, including the EDQM guideline. The control reliability is dependent of the sampling. However, a correct sampling methodology seems not to be systematically applied. Commonly, the sampling is intended to comply uniquely with the 1% specification to the produced blood components...
December 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29078757/transposable-elements-generate-population-specific-insertional-patterns-and-allelic-variation-in-genes-of-wild-emmer-wheat-triticum-turgidum-ssp-dicoccoides
#17
Katherine Domb, Danielle Keidar, Beery Yaakov, Vadim Khasdan, Khalil Kashkush
BACKGROUND: Natural populations of the tetraploid wild emmer wheat (genome AABB) were previously shown to demonstrate eco-geographically structured genetic and epigenetic diversity. Transposable elements (TEs) might make up a significant part of the genetic and epigenetic variation between individuals and populations because they comprise over 80% of the wild emmer wheat genome. In this study, we performed detailed analyses to assess the dynamics of transposable elements in 50 accessions of wild emmer wheat collected from 5 geographically isolated sites...
October 27, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29075271/identification-of-qtl-for-grain-size-and-shape-on-the-d-genome-of-natural-and-synthetic-allohexaploid-wheats-with-near-identical-aabb-genomes
#18
Lei Yan, Fei Liang, Huanwen Xu, Xiaoping Zhang, Huijie Zhai, Qixin Sun, Zhongfu Ni
Grain size and shape associated with yield and milling quality are important traits in wheat domestication and breeding. To reveal the genetic factors on the D genome that control grain size and shape variation, we conducted analysis of quantitative trait loci (QTL) using the F2 and F2:3 populations derived from a common allohexaploid wheat line TAA10 and a synthetic allohexaploid wheat XX329, which have near-identical AABB genomes and different DD genomes. Based on genotyping using wheat 660K single nucleotide polymorphism (SNP) array, TAA10 and XX329 exhibited 96...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29071747/the-management-of-anticoagulation-in-patients-undergoing-therapeutic-plasma-exchange-a-concise-review
#19
REVIEW
Sara M Shunkwiler, Huy P Pham, Geoffrey Wool, Tina S Ipe, Deanna C Fang, Elizabeth Biller, Angela Treml, John Weiss, Beverly W Baron, Mary Berg
We surveyed multiple apheresis centers represented by the authors for their clinical approach to the management of anticoagulation issues during therapeutic plasma exchange (TPE). We present the results of their practices and a review of the pertinent literature. As plasma is removed during TPE, replacement with all or partial non-plasma-containing fluids (eg, 5% albumin) may lead to significant changes in hemostasis. These changes are amplified in patients who are receiving anticoagulation. We discuss various anticoagulants as well as the monitoring and adjustment of anticoagulation before, during, and after TPE...
October 26, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/29047547/electrically-tunable-all-optical-diode-in-a-one-dimensional-photonic-crystal-structure
#20
Kazem Jamshidi-Ghaleh, Fatemeh Moslemi
All-optical-diode tunability with externally applied voltage in a one-dimensional photonic crystal structure of arrangement (BA)5 /AgLiNbO3 Ag/(AB)5 (AABB)5 was investigated. It is an asymmetric hybrid Fabry-Perot resonator which is composed of distributed Bragg reflector segments (AB5 ) containing the linear (B layers) and nonlinear (A layers) optical materials. The LiNbO3 , (LNO) sandwiched with two pairs Ag layers, is employed as a defect. The electro-optical (EO) effect and optical nonlinear response (Kerr effect) of LNO is considered...
May 10, 2017: Applied Optics
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