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https://www.readbyqxmd.com/read/29229348/bone-morphogenetic-proteins-usage-in-anterior-lumbar-inter-body-fusion-what-else-can-go-wrong
#1
Elias Elias, Zeina Nasser, Lona Winegan, Terence Verla, Ibrahim Omeis
BACKGROUND: Bone Morphogenetic Protein (BMP) graft showed promising outcome during early phases of its use. However unreported adverse events and off label use shattered its safe profile and raised concerns regarding its indication. In 2008, the Food and Drug Administration (FDA) prohibited its use in anterior cervical spine procedures due to possibility of edema, hematoma and need of intubation. At the molecular level, BMP act as multifactorial growth factors playing a role in cartilage, heart, and bone formation...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29223523/effect-of-smoking-status-on-successful-arthrodesis-clinical-outcome-and-complications-after-anterior-lumbar-interbody-fusion-alif
#2
Kevin Phan, Matthew Fadhil, Nicholas Chang, Gloria Giang, Cristian Gragnaniello, Ralph J Mobbs
BACKGROUND: Anterior lumbar interbody fusion (ALIF) is a surgical technique indicated for the treatment of several lumbar pathologies. Smoking has been suggested as a possible cause of reduced fusion rates following ALIF, though the literature regarding the impact of smoking status on lumbar spine surgery is not well established. This study aims to assess the impact of perioperative smoking status on the rates of perioperative complications, fusion and adverse clinical outcomes in patients undergoing ALIF surgery...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29191100/preliminary-results-of-anterior-lumbar-interbody-fusion-anterior-column-realignment-for-the-treatment-of-sagittal-malalignment
#3
Pooria Hosseini, Gregory M Mundis, Robert K Eastlack, Ramin Bagheri, Enrique Vargas, Stacie Tran, Behrooz A Akbarnia
OBJECTIVE Sagittal malalignment decreases patients' quality of life and may require surgical correction to achieve realignment goals. High-risk posterior-based osteotomy techniques are the current standard treatment for addressing sagittal malalignment. More recently, anterior lumbar interbody fusion, anterior column realignment (ALIF ACR) has been introduced as an alternative for correction of sagittal deformity. The objective of this paper was to report clinical and radiographic results for patients treated using the ALIF-ACR technique...
December 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/29122392/differences-in-psychosocial-determinants-of-hand-hygiene-between-health-care-professional-groups-insights-from-a-mixed-methods-analysis
#4
Muhamad Alif Bin Ibrahim, Chengzi Chow, Bee Fong Poh, Brenda Ang, Angela Chow
BACKGROUND: Good hand hygiene (HH) prevents health care-associated infections. We compared psychosocial and organizational factors associated with HH compliance and perceived need for improvement among physicians, nurses, and allied health professionals (AHPs). METHODS: We conducted a mixed-methods study in a 1,600-bed adult tertiary-care hospital in Singapore. Seven focus group discussions were conducted and data were analyzed using thematic analysis. The subsequent cross-sectional survey involved 1,064 staff members...
November 6, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29076042/interbody-fusion-techniques-in-the-surgical-management-of-degenerative-lumbar-spondylolisthesis
#5
REVIEW
Peter B Derman, Todd J Albert
PURPOSE OF REVIEW: The various lumbar interbody fusion (IBF) techniques and the evidence for their use in the treatment of degenerative lumbar spondylolisthesis (DLS) are described in this review. RECENT FINDINGS: The existing evidence is mixed regarding the indications for and utility of IBF in DLS, but its use in the setting of pre-operative instability is most strongly supported. Anterior (ALIF), lateral (LLIF), posterior (PLIF), transforaminal (TLIF), and axial (AxiaLIF) lumbar IBF approaches have been described...
December 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29062822/stand-alone-anterior-lumbar-interbody-fusion-complications-and-perioperative-results
#6
Rodrigo Amaral, Ronaldo Ferreira, Luis Marchi, Rubens Jensen, Joes Nogueira-Neto, Luiz Pimenta
OBJECTIVES: Historically, anterior lumbar interbody fusion (ALIF) was related to high rates of intraoperative complications and adverse events related to interbody devices. In recent decades, there have been technical adjustments, and cages that are more suitable have emerged. The aim of this study is to evaluate the efficacy and complication rate of the use of stand-alone mini-ALIF using a self-locking cage. METHODS: Retrospective single center study. Inclusion criteria: retroperitoneal mini-ALIF for single-level fusion (L5S1); self-locking cage; DDD/stenosis and grade I spondylolisthesis...
September 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29059483/surgical-management-of-colonic-basidiobolomycosis-among-adolescent-and-adult-patients-presentation-and-outcome
#7
Walid M Abd El Maksoud, Mohammed A Bawahab, Tarique H Ashraf, DaferM Al Shehri, Nihal I Mirza
AIM: The aim of this study was to review retrospectivelythe clinical presentations, indications for surgery and surgical outcomes of adolescent and adult patients who were diagnosed with colonic basidiobolomycosis in the last 10years. METHODS: The study was carried out in Aseer Central Hospital, Abha, Saudi Arabia by reviewing the medical files of all patients in the last 10 yearswho were diagnosed with colonic basidiobolomycosis and required surgical intervention...
October 23, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29031694/a-formative-research-guided-educational-intervention-to-improve-the-knowledge-and-attitudes-of-seniors-towards-influenza-and-pneumococcal-vaccinations
#8
Hanley J Ho, Yin Ying Chan, Muhamad Alif Bin Ibrahim, Anurupa A Wagle, Christina M Wong, Angela Chow
BACKGROUND: Adult influenza and pneumococcal vaccination rates in Singapore are low, and factors influencing knowledge and attitudes of seniors towards influenza, pneumonia and their respective vaccines are not well-known. Our study aims to understand the barriers and facilitators towards getting influenza and pneumococcal vaccinations among seniors in Singapore, and subsequently inform the conduct of a relevant community-based educational intervention, as well as evaluate the intervention outcomes...
November 7, 2017: Vaccine
https://www.readbyqxmd.com/read/28989849/can-posterior-lumbar-instrumentation-and-fusion-be-overpowered-by-anterior-lumbar-fusion-with-hyperlordotic-cages-a-cadaveric-study
#9
Nathan Wigner, Abhijeet Kadam, Philip Saville, Vincent Arlet
STUDY DESIGN: Technical report on cadavers. OBJECTIVE: To evaluate preliminary feasibility and safety of lumbar sagittal alignment correction with anterior hyperlordotic cages used to overpower previous posterior spinal instrumentation. METHODS: Hyperlordotic 30° anterior lumbar interbody fusion (ALIF) cages were inserted in collapsed L5-S1 disc space of 2 cadavers to overpower prior posterior L5-S1 pedicle screws and rod constructs. A distinct technique of opening up the disc space and creation of intersegmental lordosis was employed using a large endplate distractor and transforaminal lumbar interbody fusion (TLIF) paddle distractor...
October 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28987526/anterior-lumbar-sagittal-alignment-after-anterior-or-lateral-interbody-fusion
#10
M Afathi, F Zairi, P Devos, M Allaoui, P Marinho, D Chopin, R Assaker
PURPOSE: Anterior or lateral interbody fusion is a treatment option for lumbar disc disease. A segmental change occurs after such surgery. This study was designed to evaluate the changes in the lumbar regional alignment after a single or two-level standalone anterior or lateral interbody fusion (ALIF or LLIF). METHODS: Data from patients referred to our institution between March 2013 and November 2015 for standalone ALIF or LLIF for low-grade isthmic spondylolisthesis or degenerative discopathy were retrospectively included in our analysis...
October 4, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28985115/a-new-home-for-a-vital-conversation-introducing-the-alife-societal-impact-section-and-going-back-to-bio-inspiration-for-the-internet
#11
https://www.readbyqxmd.com/read/28973290/spinal-fusion-for-pediatric-spondylolisthesis-national-trends-complications-and-short-term-outcomes
#12
Kavelin Rumalla, Chester K Yarbrough, Andrew J Pugely, Ian G Dorward
BACKGROUND: Current surgical management guidelines for pediatric spondylolisthesis (PS) are reliant on data from single-center cohorts. OBJECTIVE: To analyze national trends and predictors of short-term outcomes in spinal fusion surgery for PS by performing a retrospective cross-sectional analysis of the Kids' Inpatient Database (KID). METHODS: The KID (sampled every 3 yr) was queried from 2003 to 2012 to identify all cases (age 5-17) of spinal fusion for PS (n = 2646)...
July 7, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28960160/overpowering-posterior-lumbar-instrumentation-and-fusion-with-hyperlordotic-anterior-lumbar-interbody-cages-followed-by-posterior-revision-a-preliminary-feasibility-study
#13
Abhijeet Kadam, Nathan Wigner, Philip Saville, Vincent Arlet
OBJECTIVE The authors' aim in this study was to evaluate whether sagittal plane correction can be obtained from the front by overpowering previous posterior instrumentation and/or fusion with hyperlordotic anterior lumbar interbody fusion (ALIF) cages in patients undergoing revision surgery for degenerative spinal conditions and/or spinal deformities. METHODS The authors report their experience with the application of hyperlordotic cages at 36 lumbar levels for ALIFs in a series of 20 patients who underwent revision spinal surgery at a single institution...
September 29, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28894689/is-stand-alone-anterior-lumbar-interbody-fusion-a-safe-and-efficacious-treatment-for-isthmic-spondylolisthesis-of-l5-s1
#14
REVIEW
Luke L Viglione, Uphar Chamoli, Ashish D Diwan
STUDY DESIGN: A systematic review. OBJECTIVE: The objective of this study was to determine the safety and efficacy of stand-alone anterior lumbar interbody fusion (sa-ALIF) for the treatment of symptomatic isthmic spondylolisthesis of L5-S1 by assessing the level of available clinical and radiographic evidence. METHODS: A systematic review utilizing Medline, Embase, and Scopus online databases was undertaken. Clinical, radiographic, and adverse outcome data were extracted for the relevant isthmic spondylolisthesis cases with the intention of undertaking a meta-analysis...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28841904/a-comparison-of-radiographic-and-clinical-outcomes-of-anterior-lumbar-interbody-fusion-performed-with-either-a-cellular-bone-allograft-containing-multipotent-adult-progenitor-cells-or-recombinant-human-bone-morphogenetic-protein-2
#15
Daniel Dongwhan Lee, John Yongmin Kim
BACKGROUND: Both the map3 Cellular Allogeneic Bone Graft® and recombinant human bone morphogenetic protein 2 (rhBMP-2, Infuse®) were developed to provide an alternative to iliac crest autograft, thus eliminating the morbidity associated with its harvest. The recent literature concerning adverse events associated with the use of rhBMP-2, however, highlights the need for a safe and effective alternative. The multipotent adult progenitor cells (MAPC) found in map3 allograft may provide this alternative...
August 25, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28811990/clinical-outcomes-of-total-disc-replacement-versus-anterior-lumbar-interbody-fusion-for-surgical-treatment-of-lumbar-degenerative-disc-disease
#16
Tobias A Mattei, Jennifer Beer, Alisson R Teles, Azeem A Rehman, Jean Aldag, Dzung Dinh
STUDY DESIGN: The authors performed a retrospective controlled study of patients diagnosed with lumbar degenerative disc disease who received surgical intervention (either total disc replacement [TDR]/Activ-L or anterior lumbar interbody fusion [ALIF]) at a single tertiary-care hospital from 2007-2010. OBJECTIVES: To investigate the clinical outcomes after TDR in comparison with ALIF for surgical treatment of lumbar degenerative disc disease (DDD). METHODS: Analyzed data included intra-operative blood loss, time to return to work, and clinical outcomes as evaluated through the Oswestry Disability Index (ODI) and the Visual Analog Scale (VAS) pain questionnaires pre-operatively and at 6 weeks, 3 months, 6 months, and 1 year postoperative follow-up...
August 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28803172/influence-of-obesity-on-complications-clinical-outcome-and-subsidence-after-anterior-lumbar-interbody-fusion-alif-prospective-observational-study
#17
Kevin Phan, Priya Rogers, Prashanth J Rao, Ralph J Mobbs
BACKGROUND: The complications associated with obesity have been well described for posterior lumbar spinal surgery. However, the influence of obesity on anterior lumbar interbody fusion (ALIF) is not well established. We aimed to compare complication risks, functional outcomes, and subsidence rates in normal-weight, overweight, and obese patients who underwent ALIF. METHODS: A total of 137 consecutive patients undergoing ALIF surgery from 2012 to 2014 were followed prospectively...
November 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28782791/occupational-exposures-to-solvents-and-metals-are-associated-with-fixed-airflow-obstruction
#18
Sheikh M Alif, Shyamali C Dharmage, Geza Benke, Martine Dennekamp, Jennifer L Burgess, Caroline J Lodge, Stephen Morrison, David P Johns, Graham G Giles, Lyle C Gurrin, Paul S Thomas, John L Hopper, Richard Wood-Baker, Bruce R Thompson, Iain H Feather, Roel Vermeulen, Hans Kromhout, E Haydn Walters, Michael J Abramson, Melanie C Matheson
Objectives This study investigated the associations between occupational exposures to solvents and metals and fixed airflow obstruction (AO) using post-bronchodilator spirometry. Methods We included 1335 participants from the 2002-2008 follow-up of the Tasmanian Longitudinal Health Study. Ever-exposure and cumulative exposure-unit (EU) years were calculated using the ALOHA plus job exposure matrix (JEM). Fixed AO was defined as post-bronchodilator forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) <0...
August 7, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28770402/kinematic-efficacy-of-supplemental-anterior-lumbar-interbody-fusion-at-lumbosacral-levels-in-thoracolumbosacral-deformity-correction-with-and-without-pedicle-subtraction-osteotomy-at-l3-an-in-vitro-cadaveric-study
#19
Benny T Dahl, Jonathan A Harris, Manasa Gudipally, Mark Moldavsky, Saif Khalil, Brandon S Bucklen
PURPOSE: Pedicle subtraction osteotomy (PSO) is performed to treat rigid, sagittal spinal deformities, but high rates of implant failure are reported. Anterior lumbar interbody fusion has been proposed to reduce this risk, but biomechanical investigation is lacking. The goal of this study was to quantify the (1) destabilizing effects of a lumbar osteotomy and (2) contribution of anterior lumbar interbody fusion (ALIF) at the lumbosacral junction as recommended in literature. METHODS: Fourteen fresh human thoracolumbosacral spines (T12-S1) were tested in flexion-extension (FE), lateral bending (LB), and axial rotation (AR)...
November 2017: European Spine Journal
https://www.readbyqxmd.com/read/28765063/indirect-decompression-and-reduction-of-lumbar-spondylolisthesis-does-not-result-in-higher-rates-of-immediate-and-long-term-complications
#20
Jacob Januszewski, Joshua M Beckman, Konrad Bach, Andrew C Vivas, Juan S Uribe
Nerve root decompression and spondylolisthesis reduction is typically reserved for open surgery. MIS techniques have been thought to be associated with higher rates of neurological complications. This study aims to report acute and chronic neurologic complications encountered with MIS surgery for spondylolisthesis, specifically, the incidence of nerve root injury and clinical and radiographic outcomes. A retrospective review of 269 patients who underwent MIS LIF or ALIF treatment for lumbar degenerative or isthmic grade 1 or 2 spondylolisthesis was conducted...
November 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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