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https://www.readbyqxmd.com/read/29454985/a-non-toxic-microbial-surfactant-from-marinobacter-hydrocarbonoclasticus-sdk644-for-crude-oil-solubilization-enhancement
#1
Billal Zenati, Alif Chebbi, Abdelmalek Badis, Kamel Eddouaouda, Hocine Boutoumi, Mohamed El Hattab, Dorra Hentati, Manel Chelbi, Sami Sayadi, Mohamed Chamkha, Andrea Franzetti
This study aims to investigate the ability of a biosurfactant produced by Marinobacter hydrocarbonoclasticus strain SdK644 isolated from hydrocarbon contaminated sediment to enhance the solubilization rate of crude oil contaminated seawater. Phylogenetic analysis shows that strain SdK644 was very closely related to M. hydrocarbonoclasticus with 16S rRNA gene sequence similarity of 97.44%. Using waste frying oil as inducer carbon source, the producing biosurfactant by strain SdK644 was applied to improve crude oil solubilization in seawater...
February 15, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29415435/review-of-current-cell-penetrating-antibody-developments-for-hiv-1-therapy
#2
REVIEW
Muhamad Alif Che Nordin, Sin-Yeang Teow
The discovery of highly active antiretroviral therapy (HAART) in 1996 has significantly reduced the global mortality and morbidity caused by the acquired immunodeficiency syndrome (AIDS). However, the therapeutic strategy of HAART that targets multiple viral proteins may render off-target toxicity and more importantly results in drug-resistant escape mutants. These have been the main challenges for HAART and refinement of this therapeutic strategy is urgently needed. Antibody-mediated treatments are emerging therapeutic modalities for various diseases...
February 6, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29413610/genipin-stabilized-caseinatehitosan-nanoparticles-for-enhanced-stability-and-anti-cancer-activity-of-curcumin
#3
Muhamad Alif Razi, Rie Wakabayashi, Yoshiro Tahara, Masahiro Goto, Noriho Kamiya
Nanoparticles formed by the assembly of protein and polysaccharides are of great interest for the delivery of hydrophobic molecules. Herein, the formation of genipin-crosslinked nanoparticles from caseinate (CS) and chitosan (CH) is reported for the delivery of curcumin, a polyphenolic compound from turmeric, to cells. Genipin-crosslinked CS-CH nanoparticles (G-CCNPs) having a diameter of ∼250 nm and a low polydispersity index showed excellent stability over a wide pH range, as indicated by dynamic light scattering and transmission electron microscopic measurements...
January 31, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29413144/sexual-risk-behavior-among-youth-with-bipolar-disorder-identifying-demographic-and-clinical-risk-factors
#4
Megan Krantz, Tina Goldstein, Brian Rooks, John Merranko, Fangzi Liao, Mary Kay Gill, Rasim Diler, Danella Hafeman, Neal Ryan, Benjamin Goldstein, Shirley Yen, Heather Hower, Jeffrey Hunt, Martin Keller, Michael Strober, David Axelson, Boris Birmaher
OBJECTIVE: This study aims to document rates of sexual activity among youth with bipolar spectrum disorder (BD) and to examine demographic and clinical factors associated with first sexual activity and sexual risk behavior during follow-up. METHOD: The sample was drawn from the Course and Outcome of Bipolar Youth (COBY) study of 413 youth 7 to 17 years at baseline who met criteria for bipolar spectrum disorder according to the Schedule for Affective Disorders and Schizophrenia for School-Aged Children...
February 2018: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29411050/-pseudarthrosis-and-construct-failure-after-lumbar-pedicle-subtraction-osteotomy-influence-of-biomechanics-surgical-technique-biology-and-avoidance-strategies
#5
REVIEW
C Birkenmaier
There are numerous factors that can lead to construct failure and pseudarthrosis after corrective pedicle subtraction osteotomy (PSO) in the lumbar spine. Frequently, several factors are of relevance in these problematic cases. This article attempts to explain the surgical, biomechanical and biological aspects that should be understood in order to minimize the risk of pseudarthrosis and construct failure. It addresses technical varieties of the PSO procedure as well as the surgical technique, the choice of rod material and the design of multirod constructs...
February 6, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29369713/alife-and-society-editorial-introduction-to-the-artificial-life-conference-2016-special-issue
#6
Jesús M Siqueiros-García, Tom Froese, Carlos Gershenson, Wendy Aguilar, Hiroki Sayama, Eduardo Izquierdo
No abstract text is available yet for this article.
January 25, 2018: Artificial Life
https://www.readbyqxmd.com/read/29369712/report-on-the-isal-special-session-on-alife-and-society-alife-xv-canc%C3%A3%C2%BAn-mexico-2016
#7
Alexandra Penn
No abstract text is available yet for this article.
January 25, 2018: Artificial Life
https://www.readbyqxmd.com/read/29354736/anterior-lumbar-interbody-fusion-alif-as-an-option-for-recurrent-disc-herniations-a-systematic-review-and-meta-analysis
#8
Kevin Phan, Alan Lackey, Nicholas Chang, Yam-Ting Ho, David Abi-Hanna, Jack Kerferd, Monish M Maharaj, Rhiannon M Parker, Gregory M Malham, Ralph J Mobbs
Background: Recurrent intervertebral disc herniation is a relatively common occurrence after primary discectomy for lumbar intervertebral disc herniation. For recurrent herniations after repeat discectomies, a growing body of evidence suggests that fusion is effective in appropriately selected cases. Theoretically, anterior lumbar interbody fusion (ALIF) allows for comprehensive discectomy, less trauma to spinal nerves and paraspinal muscles and avoidance of the disadvantages of repeat posterior approaches...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29303470/previously-unreported-complications-associated-with-integrated-cage-screws-following-anterior-lumbar-interbody-fusion-report-of-2-cases
#9
Neginder Saini, Mohammad Zaidi, Maureen T Barry, Robert F Heary
Anterior lumbar interbody fusion (ALIF) is a widely performed surgical treatment for various lumbar spine pathologies. The authors present the first reports of virtually identical cases of complications with integrated screws in stand-alone interbody cages. Two patients presented with the onset of S-1 radiculopathy due to screw misplacements following an ALIF procedure. In both cases, an integrated screw from the cage penetrated the dorsal aspect of the S-1 cortical margin of the vertebra, extended into the neural foramen, and injured the traversing left S-1 nerve roots...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29290134/minimally-invasive-anterior-and-lateral-transpsoas-approaches-for-closed-reduction-of-grade-ii-spondylolisthesis-initial-clinical-and-radiographic-experience
#10
David S Xu, Konrad Bach, Juan S Uribe
OBJECTIVE Minimally invasive anterior and lateral approaches to the lumbar spine are increasingly used to treat and reduce grade I spondylolisthesis, but concerns still exist for their usage in the management of higher-grade lesions. The authors report their experience with this strategy for grade II spondylolisthesis in a single-surgeon case series and provide early clinical and radiographic outcomes. METHODS A retrospective review of a single surgeon's cases between 2012 and 2016 identified all patients with a Meyerding grade II lumbar spondylolisthesis who underwent minimally invasive lateral lumbar interbody fusion (LLIF) or anterior lumbar interbody fusion (ALIF) targeting the slipped level...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29288274/stand-alone-anterior-interbody-fusion-for-substitution-of-iliac-fixation-in-long-spinal-fixation-constructs
#11
Morsi Khashan, William Camisa, Sigurd Berven, Jeremi Leasure
INTRODUCTION: The use of distal sacral anchorage solely, in long spinal fusions, may lead to substantial complications. Extending the fixation down to the ilium and the addition of anterior column support are both used to facilitate construct stability and improve fusion rates. In the current study, we aimed to determine whether supplementation of long thoracolumbar fixation constructs with stand-alone anterior interbody fusion (ALIF) cage with embedded screws can eliminate the biomechanical need for iliac screws fixation biomechanically...
December 29, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29285986/monoclonal-antibody-based-enzyme-immunoassay-for-detection-of-porcine-plasma-in-fish-surimi
#12
Raja Mohd Hafidz Raja Nhari, Nur Fadhilah Khairil Mokhtar, Irwan Hanish, Muhajir Hamid, Muhammad Asraf Alif Mohamed Rashidi, Nur Maisarah Shahidan
Detection of porcine plasma using indirect ELISA was developed using mAb B4E1 for the prevention of their usage in human food that creates religious and health conflicts. The immunoassay has a CV<20% and did not cross-react to other meat and non-meat proteins. The sensitivity of the assay is 0.25% (w/w) of porcine plasma in spiked raw and cooked fish surimi. The assay did not produce a false positive result for any of the commercial fish surimi tested that were not contain porcine plasma. Determination of a 60-kDa antigenic protein of porcine blood using Western Blot confirmed its presence in the plasma fraction of the porcine blood...
December 29, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29229348/bone-morphogenetic-proteins-usage-in-anterior-lumbar-inter-body-fusion-what-else-can-go-wrong
#13
Elias Elias, Zeina Nasser, Lona Winegan, Terence Verla, Ibrahim Omeis
BACKGROUND: Bone Morphogenetic Protein (BMP) graft showed promising outcome during early phases of its use. However unreported adverse events and off label use shattered its safe profile and raised concerns regarding its indication. In 2008, the Food and Drug Administration (FDA) prohibited its use in anterior cervical spine procedures due to possibility of edema, hematoma and need of intubation. At the molecular level, BMP act as multifactorial growth factors playing a role in cartilage, heart, and bone formation...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29223523/effect-of-smoking-status-on-successful-arthrodesis-clinical-outcome-and-complications-after-anterior-lumbar-interbody-fusion-alif
#14
Kevin Phan, Matthew Fadhil, Nicholas Chang, Gloria Giang, Cristian Gragnaniello, Ralph J Mobbs
BACKGROUND: Anterior lumbar interbody fusion (ALIF) is a surgical technique indicated for the treatment of several lumbar pathologies. Smoking has been suggested as a possible cause of reduced fusion rates following ALIF, though the literature regarding the impact of smoking status on lumbar spine surgery is not well established. This study aims to assess the impact of perioperative smoking status on the rates of perioperative complications, fusion and adverse clinical outcomes in patients undergoing ALIF surgery...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29191100/preliminary-results-of-anterior-lumbar-interbody-fusion-anterior-column-realignment-for-the-treatment-of-sagittal-malalignment
#15
Pooria Hosseini, Gregory M Mundis, Robert K Eastlack, Ramin Bagheri, Enrique Vargas, Stacie Tran, Behrooz A Akbarnia
OBJECTIVE Sagittal malalignment decreases patients' quality of life and may require surgical correction to achieve realignment goals. High-risk posterior-based osteotomy techniques are the current standard treatment for addressing sagittal malalignment. More recently, anterior lumbar interbody fusion, anterior column realignment (ALIF ACR) has been introduced as an alternative for correction of sagittal deformity. The objective of this paper was to report clinical and radiographic results for patients treated using the ALIF-ACR technique...
December 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/29122392/differences-in-psychosocial-determinants-of-hand-hygiene-between-health-care-professional-groups-insights-from-a-mixed-methods-analysis
#16
Muhamad Alif Bin Ibrahim, Chengzi Chow, Bee Fong Poh, Brenda Ang, Angela Chow
BACKGROUND: Good hand hygiene (HH) prevents health care-associated infections. We compared psychosocial and organizational factors associated with HH compliance and perceived need for improvement among physicians, nurses, and allied health professionals (AHPs). METHODS: We conducted a mixed-methods study in a 1,600-bed adult tertiary-care hospital in Singapore. Seven focus group discussions were conducted and data were analyzed using thematic analysis. The subsequent cross-sectional survey involved 1,064 staff members...
November 6, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29076042/interbody-fusion-techniques-in-the-surgical-management-of-degenerative-lumbar-spondylolisthesis
#17
REVIEW
Peter B Derman, Todd J Albert
PURPOSE OF REVIEW: The various lumbar interbody fusion (IBF) techniques and the evidence for their use in the treatment of degenerative lumbar spondylolisthesis (DLS) are described in this review. RECENT FINDINGS: The existing evidence is mixed regarding the indications for and utility of IBF in DLS, but its use in the setting of pre-operative instability is most strongly supported. Anterior (ALIF), lateral (LLIF), posterior (PLIF), transforaminal (TLIF), and axial (AxiaLIF) lumbar IBF approaches have been described...
December 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29062822/stand-alone-anterior-lumbar-interbody-fusion-complications-and-perioperative-results
#18
Rodrigo Amaral, Ronaldo Ferreira, Luis Marchi, Rubens Jensen, Joes Nogueira-Neto, Luiz Pimenta
OBJECTIVES: Historically, anterior lumbar interbody fusion (ALIF) was related to high rates of intraoperative complications and adverse events related to interbody devices. In recent decades, there have been technical adjustments, and cages that are more suitable have emerged. The aim of this study is to evaluate the efficacy and complication rate of the use of stand-alone mini-ALIF using a self-locking cage. METHODS: Retrospective single center study. Inclusion criteria: retroperitoneal mini-ALIF for single-level fusion (L5S1); self-locking cage; DDD/stenosis and grade I spondylolisthesis...
September 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29059483/surgical-management-of-colonic-basidiobolomycosis-among-adolescent-and-adult-patients-presentation-and-outcome
#19
Walid M Abd El Maksoud, Mohammed A Bawahab, Tarique H Ashraf, DaferM Al Shehri, Nihal I Mirza
AIM: The aim of this study was to review retrospectivelythe clinical presentations, indications for surgery and surgical outcomes of adolescent and adult patients who were diagnosed with colonic basidiobolomycosis in the last 10years. METHODS: The study was carried out in Aseer Central Hospital, Abha, Saudi Arabia by reviewing the medical files of all patients in the last 10 yearswho were diagnosed with colonic basidiobolomycosis and required surgical intervention...
October 23, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29031694/a-formative-research-guided-educational-intervention-to-improve-the-knowledge-and-attitudes-of-seniors-towards-influenza-and-pneumococcal-vaccinations
#20
Hanley J Ho, Yin Ying Chan, Muhamad Alif Bin Ibrahim, Anurupa A Wagle, Christina M Wong, Angela Chow
BACKGROUND: Adult influenza and pneumococcal vaccination rates in Singapore are low, and factors influencing knowledge and attitudes of seniors towards influenza, pneumonia and their respective vaccines are not well-known. Our study aims to understand the barriers and facilitators towards getting influenza and pneumococcal vaccinations among seniors in Singapore, and subsequently inform the conduct of a relevant community-based educational intervention, as well as evaluate the intervention outcomes...
November 7, 2017: Vaccine
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