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https://www.readbyqxmd.com/read/28532910/impact-of-elderly-age-on-complications-and-clinical-outcomes-following-anterior-lumbar-interbody-fusion-surgery
#1
Kevin Phan, Vignesh Ramachandran, Tommy Tran, Steven Phan, Prashanth J Rao, Ralph J Mobbs
BACKGROUND: Anterior Lumbar Interbody Fusion (ALIF) is a surgical technique used to treat patients with a variety of lumbar pathologies. Identification of risk factors leading to complication following ALIF surgery may allow surgeons to better judge candidacy and optimize care for high-risk patients. METHODS: A retrospective analysis was conducted on a prospectively collected database of 137 patients who all underwent ALIF surgery by a single primary spine surgeon...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28507884/a-retrospective-analysis-of-complications-associated-with-bone-morphogenetic-protein-2-in-anterior-lumbar-interbody-fusion
#2
Kevork Hindoyan, Justin Tilan, Zorica Buser, Jeremiah R Cohen, Darrel S Brodke, Jim A Youssef, Jong-Beom Park, S Tim Yoon, Hans-Joerg Meisel, Jeffrey C Wang
STUDY DESIGN: Retrospective review. OBJECTIVE: The aim of our study was to quantify the frequency of complications associated with recombinant human bone morphogenetic protein 2 (rhBMP-2) use in anterior lumbar interbody fusion (ALIF). METHODS: The orthopedic subset of the Medicare database (PearlDiver) was queried for this retrospective cohort study using International Statistical Classification of Diseases 9 (ICD-9) and Current Procedure Terminology (CPT) codes for ALIF procedures with and without rhBMP-2 between 2005 and 2010...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28507883/risk-factors-for-medical-and-surgical-complications-following-single-level-alif
#3
Winward Choy, Nikki Barrington, Roxanna M Garcia, Robert B Kim, Heron Rodriguez, Sandi Lam, Nader Dahdaleh, Zachary A Smith
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The objective of the study was to determine rates of medical and surgical postoperative complications following anterior lumbar interbody fusion (ALIF) along with their associated predictors. METHODS: Using the American College of Surgeons National Surgical Quality Improvement database, patients who underwent single-level ALIF surgery from 2006 to 2013 were identified. The 30-day rate of postoperative medical and surgical complications along with associated risk factors were evaluated by multivariable logistic regression...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28502688/evaluating-outcomes-of-stand-alone-anterior-lumbar-interbody-fusion-a-systematic-review
#4
Gloria Giang, Ralph Mobbs, Steven Phan, Tommy Manh Tran, Kevin Phan
BACKGROUND: Stand-alone anterior lumbar interbody fusion (ALIF) is an effective surgical approach for selected spinal pathologies. It avoids the morbidity and complications associated with instrumented ALIF such as plate fixation and the traditionally used posterior approach. Despite improved disc space visualisation and clearance, the associated posterior instability and increased risk of non-fusion present major challenges to this approach. The integral cage design aims to address these challenges by providing the necessary stabilisation through intracorporeal screws...
May 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28460342/anterior-lumbar-interbody-fusion-with-percutaneous-pedicle-screw-fixation-for-multiple-level-isthmic-spondylolisthesis
#5
Chang-Sheng Hsieh, Hyung Chang Lee, Hyeong-Seok Oh, Sang-Joon Park, Byeong-Wook Hwang, Sang-Ho Lee
OBJECTIVE: Multiple-level lumbar isthmic spondylolisthesis is rarely reported. Here, we report 23 consecutive patients who underwent anterior lumbar interbody fusion (ALIF) with percutaneous pedicle screw fixation (PPF) for multiple-level isthmic spondylolisthesis. PATIENTS AND METHODS: From June 2008 through December 2014, multiple-level lumbar isthmic spondylolisthesis was diagnosed in 23 patients (6 men, 17 women) at Wooridul Spine Hospital (Busan, South Korea)...
April 13, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28457926/worker-s-compensation-status-and-outcomes-following-anterior-lumbar-interbody-fusion-alif-prospective-observational-study
#6
Kevin Phan, Simon Davies, Prashanth J Rao, Ralph J Mobbs
BACKGROUND: Anterior lumbar-interbody fusion (ALIF) is a common performed procedure for degenerative spinal disorders with reasonable clinical and safety outcomes, although there is limited evidence regarding the impact of ALIF in patients receiving worker's compensation (WC) compared to those without. The aim of our study is to identify whether WC status affects the clinical outcome and rates of complication following ALIF surgery in a prospective cohort. METHODS: 114 consecutive patients undergoing ALIF surgery from 2012-2014 were prospectively followed...
April 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28433838/outcome-of-anterior-lumbar-interbody-fusion-a-retrospective-study-of-clinical-and-radiological-parameters
#7
H Pinson, G Hallaert, P Herregodts, K Everaert, T Couvreur, J Caemaert, J P Kalala, D Van Roost
OBJECTIVE: This study aims to critically evaluate the long-term results of stand-alone anterior lumbar interbody fusion (ALIF), without use of rhBMP-2, as a therapeutic option for symptomatic patients with degenerative disc disease (DDD). Furthermore this study intends to identify predictive parameters for anterior lumbar interbody fusion outcome. METHODS: A retrospective cohort study with additional telephone interview to obtain missing data was performed. All patients who underwent a L4-L5 and/or L5-S1 ALIF-procedure in the period between 2006 and 2011 were identified...
April 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28426934/from-permeation-to-cluster-arrays-graphene-on-ir-111-exposed-to-carbon-vapor
#8
Charlotte Herbig, Timo Knispel, Sabina Simon, Ulrike A Schröder, Antonio J Martínez-Galera, Mohammad A Arman, Christian Teichert, Jan Knudsen, Arkady V Krasheninnikov, Thomas Michely
Our scanning tunneling microscopy and X-ray photoelectron spectroscopy experiments along with first-principles calculations uncover the rich phenomenology and enable a coherent understanding of carbon vapor interaction with graphene on Ir(111). At high temperatures, carbon vapor not only permeates to the metal surface but also densifies the graphene cover. Thereby, in addition to underlayer graphene growth, upon cool down also severe wrinkling of the densified graphene cover is observed. In contrast, at low temperatures the adsorbed carbon largely remains on top and self-organizes into a regular array of fullerene-like, thermally highly stable clusters that are covalently bonded to the underlying graphene sheet...
April 25, 2017: Nano Letters
https://www.readbyqxmd.com/read/28377862/arthrodesis-rate-and-patient-reported-outcomes-after-anterior-lumbar-interbody-fusion-utilizing-a-plasma-sprayed-titanium-coated-peek-interbody-implant-a-retrospective-observational-analysis
#9
Joseph A Sclafani, Sophea R Bergen, Miranda Staples, Kevin Liang, Ramin Raiszadeh
BACKGROUND: Anterior lumbar interbody fusion (ALIF) is utilized in symptomatic spinal disc destabilization due to degenerative lumbar disc disease, isthmic and degenerative spondylolisthesis, internal disc disruption, or pseudarthrosis after non-operative treatments fail. The addition of a plasma-sprayed titanium coating (PTC) to polyether ether ketone spacers (PEEK) may reduce the rate of implant subsidence or non-union secondary to poor osseous-integration of non-coated PEEK or metal interbody systems...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28341194/outcomes-of-open-staged-corrective-surgery-in-the-setting-of-adult-spinal-deformity
#10
Peter G Passias, Gregory W Poorman, Cyrus M Jalai, Breton Line, Bassel Diebo, Paul Park, Robert Hart, Douglas Burton, Frank Schwab, Virginie Lafage, Shay Bess, Thomas Errico
BACKGROUND CONTEXT: Adult spinal deformity (ASD) represents a constellation of complex mal-alignments affecting the spinal column. Corrective surgical procedures aimed at improving ASD can be equally challenging, and commonly require multiple index procedures and potential revisions prior to definitive management. There is a paucity of data comparing the outcomes of same-day (simultaneous) and two-day (staged) procedures for long spinal-fusions for ASD. Utilizing a large patient cohort with surgeon and patient-reported outcomes will be particularly useful in determining the utility and effect of staging long spine fusions for ASD...
March 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28315440/optimized-production-and-characterization-of-a-detergent-stable-protease-from-lysinibacillus-fusiformis-c250r
#11
Sondes Mechri, Mouna Kriaa, Mouna Ben Elhoul Berrouina, Maroua Omrane Benmrad, Nadia Zaraî Jaouadi, Hatem Rekik, Khelifa Bouacem, Amel Bouanane-Darenfed, Alif Chebbi, Sami Sayadi, Mohamed Chamkha, Samir Bejar, Bassem Jaouadi
In this study, we aimed to optimize the cultural and nutritional conditions for protease production by Lysinibacillus fusiformis strain C250R in submerged fermentation process using statistical methodology. The most significant factors (gruel, wheat bran, yeast extract, and FeSO4) were identified by Plackett-Burman design. Response surface methodology (RSM) was used to determine the optimum levels of the screened factors and their interaction. Under the optimized conditions, protease yield 3100U/mL was 4.5 folds higher than those obtained by the use of the initial conditions (680U/mL)...
March 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28303383/surgical-management-of-coronal-and-sagittal-imbalance-of-the-spine-without-pso-a-multicentric-cohort-study-on-compensated-adult-degenerative-deformities
#12
Alessandro Ramieri, Massimo Miscusi, Maurizio Domenicucci, Antonino Raco, Giuseppe Costanzo
PURPOSE: Sagittal imbalance of severe adult degenerative deformities requires surgical correction to improve pain, mobility and quality of life. Our aim was a harmonic and balanced spine, treating a series of adult degenerative thoracolumbar and lumbar kyphoscoliosis by a non posterior subtraction osteotomy technique. METHODS: We operated 22 painful thoracolumbar and lumbar compensated degenerative deformities by anterior (ALIF), extreme lateral (XLIF) and transforaminal (TLIF) interbody fusion and grade 2 osteotomy (SPO) to restore lumbar lordosis and mobilize the coronal curve...
March 16, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28277385/transforaminal-lumbar-interbody-fusion-versus-mini-open-anterior-lumbar-interbody-fusion-with-oblique-self-anchored-stand-alone-cages-for-the-treatment-of-lumbar-disc-herniation-a-retrospective-study-with-2-year-follow-up
#13
Guohua Lü, Lei Kuang, Bing Wang
STUDY DESIGN: Retrospective study OBJECTIVE.: To evaluate the clinical and radiological outcomes of mini-open ALIF (MO-ALIF) with self-anchored stand alone cages for the treatment of lumbar disc herniation in comparison with transforaminal lumbar interbody fusion (TLIF). SUMMARY OF BACKGROUND DATA: Currently, whether ALIF is superior to TLIF for the treatment of lumbar disc herniation remains controversial. METHODS: This study retrospectively reviewed 82 patients who underwent MO-ALIF with self-anchored standalone cages (n = 42) or TLIF (n = 40) for the treatment of lumbar disc herniation between April 2013 and October 2014...
March 8, 2017: Spine
https://www.readbyqxmd.com/read/28276661/anterior-lumbar-interbody-fusion-in-left-sided-inferior-vena-cava-and-right-sided-aortic-arch
#14
Kevin Phan, Bernard A M Fang, Monish M Maharaj, Andrew F Lennox, Ralph J Mobbs
Spinal fusion via anterior lumbar interbody fusion (ALIF) can offer symptomatic relief to patients that suffer severe low back pain, radiculopathy, and claudication. However, a detailed working knowledge of the thoracic, abdominal, and lumbar anatomy, particularly of the vasculature, is vital. We report the case of a 68-year-old man who presented with radiculopathy and progressively worsening low back pain despite 9 months of unsuccessful conservative therapy and pain management. Preoperative computed tomography and magnetic resonance imaging revealed a rare anatomical variation, with an anomalous left-sided inferior vena cava and anomalous aorta...
February 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28247079/two-piece-alif-cage-optimizes-the-bone-implant-interface-in-a-360%C3%A2-setting
#15
Hans-Joachim Wilke, David Volkheimer, Bruce Robie, Finn B Christensen
INTRODUCTION: Clinical research has documented that cage subsidence and the loss of balance correction is a significant complication related to spinal fusion. Subsidence is a multifactorial complication, where implant design is one important element. The aim of the study is to compare the rigidity and bone-implant relative motion of segments treated with either a conventional one-piece ALIF cage versus a two-piece ALIF cage, which adapts in situ and permits 7°-21° of lordosis. METHODS: Seven lumbosacral (L3-S1) human cadaver specimens were tested in a universal spine tester in the intact condition, the specimens instrumented with a two-piece ALIF cage (Statur(®)-L, FBC Device, Denmark) and a one-piece ALIF cage (Pezo™-A, Ulrich GmbH & Co...
February 28, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28156000/rhamnolipids-from-pseudomonas-aeruginosa-strain-w10-as-antibiofilm-antibiofouling-products-for-metal-protection
#16
Alif Chebbi, Mohamed Elshikh, Farazul Haque, Syed Ahmed, Sara Dobbin, Roger Marchant, Sami Sayadi, Mohamed Chamkha, Ibrahim M Banat
Industrial biofouling-problems associated with the accumulation of microorganisms from flowing water and fluids on processing surfaces can cause severe problems. A Pseudomonas aeruginosa strain W10 was isolated from industrial setting and found to produce predominantly di-rhamnolipids (Rha-Rha-C10-C10) with a yield of around 10 g L(-1) and a critical micelle concentration (CMC) of 80 mg L(-1) . P. aeruginosa W10 rhamnolipids were able to disrupt up to 99% of 48 h pre-formed biofilms of the Gram-positive organisms Bacillus licheniformis CAN55, Staphylococcus capitis SH6, and a mixed culture (strains CAN55, SH6, and W10), under static conditions, at concentrations of 0...
February 3, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/28067466/anterior-lumbar-interbody-fusion-integrated-screw-cages-intrinsic-load-generation-subsidence-and-torsional-stability
#17
Yusuf Assem, Matthew H Pelletier, Ralph J Mobbs, Kevin Phan, William R Walsh
OBJECTIVE: To perform a repeatable idealized in vitro model to evaluate the effects of key design features and integrated screw fixation on unloaded surface engagement, subsidence, and torsional stability. METHODS: We evaluated four different stand-alone anterior lumbar interbody fusion (ALIF) cages with two, three, and four screw designs. Polyurethane (saw-bone) foam blocks were used to simulate the vertebral bone. Fuji Film was used to measure the contact footprint, average pressure, and load generated by fixating the cages with screws...
January 9, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28065676/rhamnolipids-from-non-pathogenic-burkholderia-thailandensis-e264-physicochemical-characterization-antimicrobial-and-antibiofilm-efficacy-against-oral-hygiene-related-pathogens
#18
Mohamed Elshikh, Scott Funston, Alif Chebbi, Syed Ahmed, Roger Marchant, Ibrahim M Banat
Biosurfactants are naturally occurring surface active compounds that have mainly been exploited for environmental applications and consumer products, with their biomedical efficacy an emerging area of research. Rhamnolipids area major group of biosurfactants that have been reported for their antimicrobial and antibiofilm efficacy. One of the main limiting factors for scaled up production and downstream applications of rhamnolipids is the fact that they are predominantly produced from the opportunistic pathogen Pseudomonas aeruginosa...
May 25, 2017: New Biotechnology
https://www.readbyqxmd.com/read/28050828/tissue-culture-for-xylem-differentiation-with-arabidopsis-leaves
#19
Masato Saito, Alif Meem Nurani, Yuki Kondo, Hiroo Fukuda
Culture systems combined with molecular biological approaches have identified various key factors regulating vascular differentiation, which makes a great contribution to development of vascular biology. Recently, we established a novel culture system for xylem cell differentiation in the model plant Arabidopsis thaliana (Arabidopsis), in which ectopic xylem cells can be induced throughout leaf disks within 3-4 days. Here we describe detailed procedures of the culture system from sample preparation to vascular cell induction culture...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28043848/surgical-treatment-of-degenerative-spondylolisthesis
#20
REVIEW
P Guigui, E Ferrero
Degenerative spondylolisthesis is a common pathology, often causing lumbar canal stenosis. There is, however, no strong consensus regarding the various medical and surgical treatments available. Surgery is indicated mainly for perceived functional impairment; when the indication is accepted, several questions determine the choice of surgical strategy. Improvement in neurological symptoms is one of the main treatment objectives. For this, it is useful to perform radicular decompression. Some authors recommend indirect decompression by interbody fusion (ALIF, TLIF, XLIF), others by means of an interspinous spacer but the most frequent technique is direct posterior decompression...
December 30, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
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