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https://www.readbyqxmd.com/read/29315008/clostridium-perfringens-contamination-in-retail-meat-and-meat-based-products-in-bursa-turkey
#1
Artun Yibar, Ece Cetin, Zafer Ata, Evren Erkose, Mustafa Tayar
This study examined the incidence of Clostridium perfringens in raw, ready-to-cook (RTC), and ready-to-eat (RTE) meat and meat-based products (N = 306) collected from restaurants, supermarkets, and butcher shops in Bursa, Turkey. In addition, we investigated the presence of the C. perfringens enterotoxin (CPE), as well as cpe genes and their source (chromosomal or plasmid borne). In this study, tryptose sulfite cycloserine (TSC) agar for classic culture isolation and API and real-time polymerase chain reaction (RT-PCR) techniques were used to identify C...
January 9, 2018: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29295017/client-violence-against-youth-care-workers-findings-of-an-exploratory-study-of-workforce-issues-in-residential-treatment
#2
Yvonne Smith, Lex Colletta, Anna E Bender
Residential treatment centers (RTCs) for youth are plagued by high turnover of youth care workers who provide round-the-clock treatment and supervision to youth with severe affective and behavioral problems. This article presents findings from a 15-month ethnographic study of workforce issues in one RTC related to youth care workers' exposure to client violence (CV). Findings are based on 65 semistructured interviews and 490 hours of participant observation with consenting employees. Participants reported CV incidents, including punching, kicking, biting, hair pulling, choking, threats or assaults with a weapon, and other physical and sexualized violence...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29284186/repeatability-of-gait-analysis-measurements-in-thoroughbreds-in-training
#3
M F Sepulveda Caviedes, B S Forbes, T Pfau
BACKGROUND: With the view of implementing gait symmetry measurements in Thoroughbreds in training for early detection of injuries, repeatability of inertial measurement unit (IMU) gait parameters needs to be established. OBJECTIVES: To assess the variation of head and pelvis movement symmetry in Thoroughbreds in training. STUDY DESIGN: Repeated observations in horses in race training. METHODS: Daily and weekly repeat gait assessments were conducted in 14 Thoroughbreds equipped with IMUs on poll, sacrum and right (RTC) and left (LTC) tuber coxae...
December 28, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29211888/combined-oral-contraception-and-bicalutamide-in-polycystic-ovary-syndrome-and-severe-hirsutism-a-double-blind-rtc
#4
Costanzo Moretti, Laura Guccione, Paola Di Giacinto, Ilaria Simonelli, Caterina Exacoustos, Vincenzo Toscano, Cecilia Motta, Vincenzo De Leo, Felice Petraglia, Andrea Lenzi
Background: Hirsutism is frequently expressed in women affected by polycystic ovary syndrome (PCOS). The efficacy of oral contraceptive pill (OC) plus anti-androgens in the treatment of its severe expression is controversial due to the lack of randomized double-blind long-term studies. Aim: The primary outcome was the reduction of hirsutism in PCOS women objectively measured by videodermoscopy (VD) on the androgen-sensitive skin areas assessed by the modified Ferriman&Gallwey (mF&G) total score, after 12 months of therapy with OC+Bicalutamide (BC) versus OC plus placebo (P)...
December 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29197242/alcohol-and-illicit-drugs-in-drivers-involved-in-road-traffic-crashes-in-the-milan-area-a-comparison-with-normal-traffic-reveals-the-possible-inadequacy-of-current-cut-off-limits
#5
Davide Ferrari, Monica Manca, Giuseppe Banfi, Massimo Locatelli
BACKGROUND: Driving under the influence of alcohol and/or illicit drugs in Italy is regulated by the articles 186 and 187 of the National Street Code. Epidemiological studies on drivers involved in road traffic crashes (RTC) provide useful information about the use/abuse of these substances in the general population. Comparison with case control studies may reveal important information like the cut-off limits adequacy. METHODS: Data from 1587 blood tests for alcohol and 1258 blood tests for illicit drugs on drivers involved in RTC around Milan between 2012 and 2016, were analyzed and compared with a published random survey (DRUID) from the European Community...
November 22, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29167338/inhibition-of-cytosolic-phospholipase-a2%C3%AE-impairs-an-early-step-of-coronavirus-replication-in-cell-culture
#6
Christin Müller, Martin Hardt, Dominik Schwudke, Benjamin W Neuman, Stephan Pleschka, John Ziebuhr
Coronavirus replication is associated with intracellular membrane rearrangements in infected cells, resulting in the formation of double membrane vesicles (DMV) and other membranous structures that are referred to as replicative organelles (RO). The latter provide a structural scaffold for viral replication/transcription complexes (RTC) and help to sequester RTC components from recognition by cellular factors involved in antiviral host responses. There is increasing evidence that plus-strand (+) RNA virus replication, including RO formation and virion morphogenesis, affects cellular lipid metabolism and critically depends on enzymes involved in lipid synthesis and processing...
November 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29121906/impaired-contractile-function-of-the-supraspinatus-in-the-acute-period-following-a-rotator-cuff-tear
#7
Ana P Valencia, Shama R Iyer, Espen E Spangenburg, Mohit N Gilotra, Richard M Lovering
BACKGROUND: Rotator cuff (RTC) tears are a common clinical problem resulting in adverse changes to the muscle, but there is limited information comparing histopathology to contractile function. This study assessed supraspinatus force and susceptibility to injury in the rat model of RTC tear, and compared these functional changes to histopathology of the muscle. METHODS: Unilateral RTC tears were induced in male rats via tenotomy of the supraspinatus and infraspinatus...
November 9, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29082638/the-effect-of-changes-in-pain-expectations-on-persistent-pain-following-a-road-traffic-crash
#8
S L Edmed, K M Moss, J Warren, J Kenardy
BACKGROUND: Recovery expectations can influence outcomes after injury, but little is known about the course of expectations over time or factors predicting changes in expectations. This study aimed to describe how expectations of persistent pain change over time following a non-catastrophic injury sustained in a road traffic crash (RTC); identify the early predictors of change in expectations over time; and examine whether change in expectations predicted pain at 24 months post-RTC. METHODS: One hundred and seventy-seven participants (Mage = 49...
October 30, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29062345/distraction-related-road-traffic-collisions
#9
Hani O Eid, Fikri M Abu-Zidan
OBJECTIVES: We aimed to prospectively study distraction-related road traffic collision injuries, their contributory factors, severity, and outcome. METHODS: Data were prospectively collected on all hospitalized road traffic collision trauma patients in Al-Ain City who were drivers at the collision time over one and half years. Driver's inattentive behaviors preceding the collision were collected by interviewing the admitted drivers. RESULTS: There were 444 drivers, 330 of them were fully oriented patients, out of them only 44 (13%) were distracted...
June 2017: African Health Sciences
https://www.readbyqxmd.com/read/29058715/estimating-the-causal-tissues-for-complex-traits-and-diseases
#10
Halit Ongen, Andrew A Brown, Olivier Delaneau, Nikolaos I Panousis, Alexandra C Nica, Emmanouil T Dermitzakis
How to interpret the biological causes underlying the predisposing markers identified through genome-wide association studies (GWAS) remains an open question. One direct and powerful way to assess the genetic causality behind GWAS is through analysis of expression quantitative trait loci (eQTLs). Here we describe a new approach to estimate the tissues behind the genetic causality of a variety of GWAS traits, using the cis-eQTLs in 44 tissues from the Genotype-Tissue Expression (GTEx) Consortium. We have adapted the regulatory trait concordance (RTC) score to measure the probability of eQTLs being active in multiple tissues and to calculate the probability that a GWAS-associated variant and an eQTL tag the same functional effect...
December 2017: Nature Genetics
https://www.readbyqxmd.com/read/28973641/l-carnitine-via-ppar%C3%AE-and-sirt1-dependent-mechanisms-attenuates-epithelial-mesenchymal-transition-and-renal-fibrosis-caused-by-perfluorooctanesulfonate
#11
Hsiu-Chu Chou, Li-Li Wen, Chih-Cheng Chang, Chien-Yu Lin, Lu Jin, Shu-Hui Juan
We have previously reported that perfluorooctanesulfonate (PFOS) causes cell apoptosis in renal tubular epithelial cells (RTCs). Here, we extend our findings and provide evidence of epithelial-mesenchymal transition (EMT)-associated renal fibrosis caused by PFOS and the protection by L-carnitine. Our results demonstrate that PFOS increased the expression of EMT and renal injury biomarkers (e.g., N-cadherin, vimentin, Snail, Kim1, and Lcn2). Additionally, PFOS caused EMT induction through Sirt1-mediated PPARγ deacetylation and inactivation...
August 30, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28917316/humoral-and-cytokine-response-elicited-during-immunisation-with-recombinant-immune-mapped-protein-1-etimp-1-and-oocysts-of-eimeria-tenella
#12
Krishnendu Kundu, Rajat Garg, Saroj Kumar, Mrityunjay Mandal, Fiona M Tomley, Damer P Blake, Partha Sarathi Banerjee
Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine candidate; in the present study allelic polymorphism was assessed across the IMP-1 coding sequence in E. tenella isolates from four countries and compared with the UK reference Houghton strain. Nucleotide diversity was low, limited to expansion/contraction of a CAG triplet repeat and five substitutions, three of which were non-synonymous...
September 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28915305/trauma-epidemiology-of-women-in-puerto-rico-2002-2011
#13
Sofía Muns-Aponte, Omar García-Rodríguez, Ediel O Ramos-Meléndez, Pablo Rodríguez-Ortiz
OBJECTIVE: Recent literature has suggested that trauma is heterogenic and that physiological response to it differs between sexes. The study represented in this manuscript aimed to describe gender differences in the mortality rates of trauma patients at the Puerto Rico Trauma Hospital (PRTH). MATERIALS AND METHODS: This was a cross-sectional study performed at PRTH. A total of 14,874 injured patients admitted to the hospital from 2002 to 2011 were included in the sample and divided into 2 groups, based on sex...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28910684/the-effect-of-ambient-light-condition-on-road-traffic-collisions-involving-pedestrians-on-pedestrian-crossings
#14
Jim Uttley, Steve Fotios
Previous research suggests darkness increases the risk of a collision involving a pedestrian and the severity of any injury suffered. Pedestrian crossings are intended to make it safer to cross the road, but it is not clear whether they are effective at doing this after-dark, compared with during daylight. Biannual clock changes resulting from transitions to and from daylight saving time were used to compare RTCs in the UK during daylight and darkness but at the same time of day, thus controlling for potential influences on RTC numbers not related to the ambient light condition...
November 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28879632/real-time-clustered-multiple-signal-classification-rtc-music
#15
Christoph Dinh, Lorenz Esch, Johannes Rühle, Steffen Bollmann, Daniel Güllmar, Daniel Baumgarten, Matti S Hämäläinen, Jens Haueisen
Magnetoencephalography (MEG) and electroencephalography provide a high temporal resolution, which allows estimation of the detailed time courses of neuronal activity. However, in real-time analysis of these data two major challenges must be handled: the low signal-to-noise ratio (SNR) and the limited time available for computations. In this work, we present real-time clustered multiple signal classification (RTC-MUSIC) a real-time source localization algorithm, which can handle low SNRs and can reduce the computational effort...
September 6, 2017: Brain Topography
https://www.readbyqxmd.com/read/28878073/characterization-of-a-replicating-mammalian-orthoreovirus-with-tetracysteine-tagged-%C3%AE-ns-for-live-cell-visualization-of-viral-factories
#16
Luke D Bussiere, Promisree Choudhury, Bryan Bellaire, Cathy L Miller
Within infected host cells, mammalian orthoreovirus (MRV) forms viral factories (VFs), which are sites of viral transcription, translation, assembly, and replication. The MRV nonstructural protein μNS comprises the structural matrix of VFs and is involved in recruiting other viral proteins to VF structures. Previous attempts have been made to visualize VF dynamics in live cells, but due to current limitations in recovery of replicating reoviruses carrying large fluorescent protein tags, researchers have been unable to directly assess VF dynamics from virus-produced μNS...
November 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28854385/performance-evaluation-of-a-smart-buffer-control-at-a-wastewater-treatment-plant
#17
P van Daal-Rombouts, L Benedetti, J de Jonge, S Weijers, J Langeveld
Real time control (RTC) is increasingly seen as a viable method to optimise the functioning of wastewater systems. Model exercises and case studies reported in literature claim a positive impact of RTC based on results without uncertainty analysis and flawed evaluation periods. This paper describes two integrated RTC strategies at the wastewater treatment plant (WWTP) Eindhoven, the Netherlands, that aim to improve the use of the available tanks at the WWTP and storage in the contributing catchments to reduce the impact on the receiving water...
November 15, 2017: Water Research
https://www.readbyqxmd.com/read/28815336/treatment-selection-in-oropharyngeal-cancer-a-surveillance-epidemiology-and-end-results-seer-patterns-of-care-analysis
#18
Nitin A Pagedar, Catherine Chioreso, Jennifer A Schlichting, Charles F Lynch, Mary E Charlton
PURPOSE: Treatment for oropharyngeal cancer (OPC) has changed over the past two decades under multiple influences. We provide a population-based description of the application of radiotherapy, surgery, and chemotherapy to OPC in 1997, 2004, and 2009. METHODS: The National Cancer Institute's Patterns of Care study for OPC included multiple variables not available in the public-use dataset. We identified factors correlating with selection of primary surgery versus radiotherapy with or without chemotherapy (RTC) and analyzed predictors of all-cause mortality...
October 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28805691/structural-and-neuronal-integrity-measures-of-fatigue-severity-in-multiple-sclerosis
#19
Evanthia Bernitsas, Kalyan Yarraguntla, Fen Bao, Rishi Sood, Carla Santiago-Martinez, Rajkumar Govindan, Omar Khan, Navid Seraji-Bozorgzad
Fatigue is a common and disabling symptom in Multiple Sclerosis (MS). However, consistent neuroimaging correlates of its severity are not fully elucidated. In this article, we study the neuronal correlates of fatigue severity in MS. Forty-three Relapsing Remitting MS (RRMS) patients with MS-related fatigue (Fatigue Severity Scale (FSS) range: 1-7) and Expanded Disability Status Scale (EDSS) ≤ 4, were divided into high fatigue (HF, FSS ≥ 5.1) and low fatigue groups (LF, FSS ≤ 3). We measured T2 lesion load using a semi-automated technique...
August 12, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28783322/cost-effective-river-water-quality-management-using-integrated-real-time-control-technology
#20
Fanlin Meng, Guangtao Fu, David Butler
Integrated real-time control (RTC) of urban wastewater systems is increasingly presented as a promising and emerging strategy to deliver improved surface water quality by responsive operation according to real-time data collected from the sewer system, treatment plant, and the receiving water. However, the detailed benefits and costs associated with integrated RTC have yet to be comprehensively evaluated. Built on state-of-the-art modeling and analytical tools, a three-step framework is proposed to develop integrated RTC strategies which cost-effectively maximize environmental outcomes...
August 22, 2017: Environmental Science & Technology
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