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https://www.readbyqxmd.com/read/29045713/scportalen-human-and-mouse-single-cell-centric-database
#1
Imad Abugessaisa, Shuhei Noguchi, Michael Böttcher, Akira Hasegawa, Tsukasa Kouno, Sachi Kato, Yuhki Tada, Hiroki Ura, Kuniya Abe, Jay W Shin, Charles Plessy, Piero Carninci, Takeya Kasukawa
Published single-cell datasets are rich resources for investigators who want to address questions not originally asked by the creators of the datasets. The single-cell datasets might be obtained by different protocols and diverse analysis strategies. The main challenge in utilizing such single-cell data is how we can make the various large-scale datasets to be comparable and reusable in a different context. To challenge this issue, we developed the single-cell centric database 'SCPortalen' (http://single-cell...
October 17, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29044439/liver-masses-what-physicians-need-to-know-about-ordering-and-interpreting-liver-imaging
#2
REVIEW
Arman Sheybani, Ron C Gaba, R Peter Lokken, Senta M Berggruen, Winnie A Mar
PURPOSE OF REVIEW: This paper reviews diagnostic imaging techniques used to characterize liver masses and the imaging characteristics of the most common liver masses. RECENT FINDINGS: The role of recently adopted ultrasound and magnetic resonance imaging contrast agents will be emphasized. Contrast-enhanced ultrasound is an inexpensive exam which can confirm benignity of certain liver masses without ionizing radiation. Magnetic resonance imaging using hepatocyte-specific gadolinium-based contrast agents can help confirm or narrow the differential diagnosis of liver masses...
October 18, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29043428/magnetic-resonance-imaging-for-clinical-management-of-rectal-cancer-updated-recommendations-from-the-2016-european-society-of-gastrointestinal-and-abdominal-radiology-esgar-consensus-meeting
#3
Regina G H Beets-Tan, Doenja M J Lambregts, Monique Maas, Shandra Bipat, Brunella Barbaro, Luís Curvo-Semedo, Helen M Fenlon, Marc J Gollub, Sofia Gourtsoyianni, Steve Halligan, Christine Hoeffel, Seung Ho Kim, Andrea Laghi, Andrea Maier, Søren R Rafaelsen, Jaap Stoker, Stuart A Taylor, Michael R Torkzad, Lennart Blomqvist
OBJECTIVES: To update the 2012 ESGAR consensus guidelines on the acquisition, interpretation and reporting of magnetic resonance imaging (MRI) for clinical staging and restaging of rectal cancer. METHODS: Fourteen abdominal imaging experts from the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) participated in a consensus meeting, organised according to an adaptation of the RAND-UCLA Appropriateness Method. Two independent (non-voting) Chairs facilitated the meeting...
October 17, 2017: European Radiology
https://www.readbyqxmd.com/read/29043423/preliminary-report-from-the-world-health-organisation-chest-radiography-in-epidemiological-studies-project
#4
REVIEW
Nasreen Mahomed, Nicholas Fancourt, John de Campo, Margaret de Campo, Aliu Akano, Thomas Cherian, Olivia G Cohen, David Greenberg, Stephen Lacey, Neera Kohli, Henrique M Lederman, Shabir A Madhi, Veronica Manduku, Eric D McCollum, Kate Park, Jose Luis Ribo-Aristizabal, Naor Bar-Zeev, Katherine L O'Brien, Kim Mulholland
Childhood pneumonia is among the leading infectious causes of mortality in children younger than 5 years of age globally. Streptococcus pneumoniae (pneumococcus) is the leading infectious cause of childhood bacterial pneumonia. The diagnosis of childhood pneumonia remains a critical epidemiological task for monitoring vaccine and treatment program effectiveness. The chest radiograph remains the most readily available and common imaging modality to assess childhood pneumonia. In 1997, the World Health Organization Radiology Working Group was established to provide a consensus method for the standardized definition for the interpretation of pediatric frontal chest radiographs, for use in bacterial vaccine efficacy trials in children...
October 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29043422/guidelines-for-the-use-of-chest-radiographs-in-community-acquired-pneumonia-in-children-and-adolescents
#5
REVIEW
Savvas Andronikou, Elena Lambert, Jarred Halton, Lucy Hilder, Iona Crumley, Mark D Lyttle, Cara Kosack
National guidance from the United Kingdom and the United States on community-acquired pneumonia in children states that chest radiographs are not recommended routinely in uncomplicated cases. The main reason in the ambulatory setting is that there is no evidence of a substantial impact on clinical outcomes. However clinical practice and adherence to guidance is multifactorial and includes the clinical context (developed vs. developing world), the confidence of the attending physician, the changing incidence of complications (according to the success of immunisation programs), the availability of alternative imaging (and its relationship to perceived risks of radiation) and the reliability of the interpretation of imaging...
October 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29043420/lung-ultrasound-for-the-diagnosis-of-community-acquired-pneumonia-in-children
#6
REVIEW
Jacob A M Stadler, Savvas Andronikou, Heather J Zar
Ultrasound (US) has been proposed as an alternative first-line imaging modality to diagnose community-acquired pneumonia in children. Lung US has the potential benefits over chest radiography of being radiation free, subject to fewer regulatory requirements, relatively lower cost and with immediate bedside availability of results. However, the uptake of lung US into clinical practice has been slow and it is not yet included in clinical guidelines for community-acquired pneumonia in children. The aim of this review is to give an overview of the equipment and techniques used to perform lung US in children with suspected pneumonia and the interpretation of relevant sonographic findings...
October 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29042460/storage-compartments-for-capillary-water-rarely-refill-in-an-intact-woody-plant
#7
Thorsten Knipfer, Italo Cuneo, Jeffrey Mason Earles, Clarissa Reyes, Craig Brodersen, Andrew J McElrone
Water storage is thought to play an integral role in the maintenance of whole plant water balance. The contribution of both living and dead cells to water storage can be derived from rehydration and pressure-volume curves on excised plant material, but the underlying tissue-specific emptying/refilling dynamics remain unclear. Here, we used X-ray computed micro-tomography (microCT) to characterize refilling of xylem fibers, pith cells and vessels under both excised and in-vivo conditions in Laurus nobilis. In excised stems supplied with H2O, water uptake exhibited a biphasic response curve, and microCT images showed that high water storage capacitance was associated with fiber and pith refilling as driven by capillary forces; fibers refilled more rapidly than pith cells while vessel refilling was minimal...
October 17, 2017: Plant Physiology
https://www.readbyqxmd.com/read/29042120/pilot-study-on-the-impact-of-f18-labeled-thymidine-pet-ct-on-gross-tumor-volume-identification-and-definition-for-pancreatic-cancer
#8
Jennifer L Pretz, Michael A Blake, Joseph H Killoran, Harvey J Mamon, Jennifer Y Wo, Andrew X Zhu, Theodore S Hong
PURPOSE: Accurate target definition for radiation therapy planning in localized pancreatic cancer is critical, particularly when using strategies that omit elective coverage. Standard imaging modalities such as computed tomography (CT), magnetic resonance imaging, and endoscopic ultrasound have limited concordance with pathologic evaluation. Biologic imaging with [F18]-fluorodeoxyglucose (FDG)-positron emission tomography (PET) can also be difficult to interpret because increased activity is indicative of increased glucose metabolism, rather than cellular proliferation...
September 18, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29042095/can-emergency-physicians-accurately-distinguish-retinal-detachment-from-posterior-vitreous-detachment-with-point-of-care-ocular-ultrasound
#9
Nicola Baker, Richard Amini, Elaine H Situ-LaCasse, Josie Acuña, Tomas Nuño, Uwe Stolz, Srikar Adhikari
STUDY OBJECTIVE: There is significant overlap between the symptoms of patients presenting with retinal detachment (RD) and posterior vitreous detachment (PVD). Urgency to obtain consultation and treatment are dependent on the ability to accurately distinguish these two conditions. The objective of this study was to determine the ability of emergency physicians to differentiate RDs from PVDs using point-of-care (POC) ocular ultrasound. METHODS: Single blinded cross-sectional study at an academic medical center...
October 13, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29041986/fluorescence-optical-imaging-in-pediatric-patients-with-inflammatory-and-non-inflammatory-joint-diseases-a-comparative-study-with-ultrasonography
#10
Marisa Christin Beck, Anne-Marie Glimm, Sarah Ohrndorf, Kirsten Minden, Ralf Trauzeddel, Stephanie Gabriele Werner, Gerd Horneff, Marina Backhaus, Gerd Rüdiger Burmester, Tilmann Kallinich, Hermann Girschick, Jens Klotsche
BACKGROUND: Valid detection of arthritis is essential in differential diagnosis of joint pain. Indocyanin green (ICG)-enhanced fluorescence optical imaging (FOI) is a new imaging method that visualizes inflammation in wrist and finger joints. Objectives of this study were to compare FOI with ultrasonography (US, by gray-scale (GS) and power Doppler (PD)) and clinical examination (CE) and to estimate the predictive power of FOI for discrimination between inflammatory and non-inflammatory juvenile joint diseases...
October 17, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29040453/detection-of-sputum-by-interpreting-the-time-frequency-distribution-of-respiratory-sound-signal-using-image-processing-techniques
#11
Jinglong Niu, Yan Shi, Maolin Cai, Zhixin Cao, Dandan Wang, Zhaozhi Zhang, Xiaohua Douglas Zhang
Motivation: Sputum in the trachea is hard to expectorate and detect directly for the patients who are unconscious, especially those in Intensive Care Unit (ICU). Medical staff should always check the condition of sputum in the trachea. This is time-consuming and the necessary skills are difficult to acquire. Currently, there are few automatic approaches to serve as alternatives to this manual approach. Results: We develop an automatic approach to diagnose the condition of the sputum...
October 13, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29040146/the-role-of-preoperative-imaging-in-the-management-of-nonsyndromic-lambdoid-craniosynostosis
#12
Kavitha Ranganathan, Antonio Rampazzo, Asra Hashmi, Karin Muraszko, Jennifer Strahle, Christian J Vercler, Steven R Buchman
BACKGROUND: The necessity of imaging for patients with craniosynostosis is controversial. Lambdoid synostosis is known to be associated with additional anomalies, but the role of imaging in this setting has not been established. The purpose of this study was to evaluate the impact of preoperative imaging on intraoperative and postoperative management among patients undergoing operative intervention for lambdoid craniosynostosis. METHODS: A retrospective review of patients undergoing cranial vault remodeling for lambdoid craniosynostosis between January 2006 and 2014 was conducted...
October 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29039692/imaging-spectrum-of-immunomodulating-chemotherapeutic-and-radiation-therapy-related-intracranial-effects
#13
Christie Mary Lincoln, Peter Fata, Susan Sotardi, Michael Pohlen, Tomas Uribe, Jacqueline A Bello
OBJECTIVE: A wide range of treatment-related side effects result in specific neurologic symptoms and signs and neuroimaging features. Even to the most seasoned neuroradiologist, elucidating therapy-related side effects from other common mimics can be challenging. We provide a pictorial survey of some common and uncommon medication induced and therapy related neuroimaging manifestations, discuss pathophysiology and common pitfalls in imaging and diagnosis. METHODS/RESULTS: A case based review is utilized to depict scenarios on a routine basis in a general radiology or neuroradiology practice such as medication induced PRES to the more challenging cases of pseudoprogression and pseudoregression in temozolmide and bevacizumab therapy in gliobastoma treatment protocols...
October 17, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29037595/cellular-characterization-of-optical-coherence-tomography-and-outer-retinal-bands-using-specific-immunohistochemistry-markers-and-clinical-implications
#14
Nicolás Cuenca, Isabel Ortuño-Lizarán, Isabel Pinilla
PURPOSE: Optical coherence tomography has been a technological breakthrough in the diagnosis, treatment, and follow-up of many ocular diseases, especially retinal and neuro-ophthalmologic pathologic conditions. Until now, several controversies have arisen over the specific cell types that the bands observed in the OCT represent, especially over the 4 outer retinal bands. DESIGN: To correlate the 4 outer hyperreflective bands observed in the OCT with the histologic structures using human retinal sections and immunocytochemistry at the fovea level...
October 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29036892/adaptive-enhancement-of-x-band-marine-radar-imagery-to-detect-oil-spill-segments
#15
Peng Liu, Ying Li, Jin Xu, Xueyuan Zhu
Oil spills generate a large cost in environmental and economic terms. Their identification plays an important role in oil-spill response. We propose an oil spill detection method with improved adaptive enhancement on X-band marine radar systems. The radar images used in this paper were acquired on 21 July 2010, from the teaching-training ship "YUKUN" of the Dalian Maritime University. According to the shape characteristic of co-channel interference, two convolutional filters are used to detect the location of the interference, followed by a mean filter to erase the interference...
October 14, 2017: Sensors
https://www.readbyqxmd.com/read/29036114/stochastic-calculus-analysis-of-optical-time-of-flight-range-imaging-and-estimation-of-radial-motion
#16
Lee Streeter
Time-of-flight range imaging is analyzed using stochastic calculus. Through a series of interpretations and simplifications, the stochastic model leads to two methods for estimating linear radial velocity: maximum likelihood estimation on the transition probability distribution between measurements, and a new method based on analyzing the measured correlation waveform and its first derivative. The methods are tested in a simulated motion experiment from (-40)-(+40)  m/s, with data from a camera imaging an object on a translation stage...
July 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29036073/principles-of-image-reconstruction-in-optical-interferometry-tutorial
#17
Éric Thiébaut, John Young
This paper provides a general introduction to the problem of image reconstruction from interferometric data. A simple model of the interferometric observables is given, and the issues arising from sparse Fourier data are discussed. The effects of various regularizations are described. In the proposed general framework, most existing algorithms can be understood. For an astronomer, such an understanding is crucial not only for selecting and using an algorithm but also to ensure correct interpretation of the resulting image...
June 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29034359/the-definition-rationale-and-effects-of-thresholding-in-oct-angiography
#18
Emily D Cole, Eric M Moult, Sabin Dang, WooJhon Choi, Stefan B Ploner, ByungKun Lee, Ricardo Louzada, Eduardo Novais, Julia Schottenhamml, Lennart Husvogt, Andreas Maier, James G Fujimoto, Nadia K Waheed, Jay S Duker
PURPOSE: To examine the definition, rationale, and effects of thresholding in OCT angiography (OCTA). DESIGN: A theoretical description of OCTA thresholding in combination with qualitative and quantitative analysis of the effects of OCTA thresholding in eyes from a retrospective case series. PARTICIPANTS: Four eyes were qualitatively examined: 1 from a 27-year-old control, 1 from a 78-year-old exudative age-related macular degeneration (AMD) patient, 1 from a 58-year-old myopic patient, and 1 from a 77-year-old nonexudative AMD patient with geographic atrophy (GA)...
September 2017: Ophthalmology retina
https://www.readbyqxmd.com/read/29034066/novel-spect-technologies-and-approaches-in-cardiac-imaging
#19
Piotr Slomka, Guang-Uei Hung, Guido Germano, Daniel S Berman
Recent novel approaches in myocardial perfusion single photon emission CT (SPECT) have been facilitated by new dedicated high-efficiency hardware with solid-state detectors and optimized collimators. New protocols include very low-dose (1 mSv) stress-only, two-position imaging to mitigate attenuation artifacts, and simultaneous dual-isotope imaging. Attenuation correction can be performed by specialized low-dose systems or by previously obtained CT coronary calcium scans. Hybrid protocols using CT angiography have been proposed...
December 1, 2016: Cardiovasc Innov Appl
https://www.readbyqxmd.com/read/29033687/interpretation-and-diplomacy-aspects-of-authority-and-care-in-imaging-reports
#20
Werner Albert Golder
Whereas the creative performance of the physician for nuclear medicine is measured against his/her written report, the value of the message will not only be judged by the precision of the medical statement. The same result can be attributed to different words. Numerous habitual and accidental factors exert influence on the decision on what is said and what is not said, how it is assessed, and what is ignored. The less certain a diagnosis is, and the less favorable its possible consequences are, the more subtleties and paraphrases should be expected within the report...
October 2017: World Journal of Nuclear Medicine
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