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international journal of epidemiology

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https://www.readbyqxmd.com/read/29298301/mapping-of-global-scientific-research-in-comorbidity-and-multimorbidity-a-cross-sectional-analysis
#1
Ferrán Catalá-López, Adolfo Alonso-Arroyo, Matthew J Page, Brian Hutton, Rafael Tabarés-Seisdedos, Rafael Aleixandre-Benavent
BACKGROUND: The management of comorbidity and multimorbidity poses major challenges to health services around the world. Analysis of scientific research in comorbidity and multimorbidity is limited in the biomedical literature. This study aimed to map global scientific research in comorbidity and multimorbidity to understand the maturity and growth of the area during the past decades. METHODS AND FINDINGS: This was a cross-sectional analysis of the Web of Science...
2018: PloS One
https://www.readbyqxmd.com/read/29227721/chinese-guidelines-for-childhood-asthma-2016-major-updates-recommendations-and-key-regional-data
#2
Jianguo Hong, Yixiao Bao, Aihuan Chen, Changchong Li, Li Xiang, Chuanhe Liu, Zhimin Chen, Deyu Zhao, Zhou Fu, Yunxiao Shang
OBJECTIVE: With increased industrialization and urbanization in China, pediatric asthma is becoming more prevalent. Despite a growing body of evidence, there remains a significant unmet need for adequate management of childhood asthma. The Subspecialty Group of Respiratory Diseases of the Society of Pediatrics, the Chinese Medical Association, and the editorial board of the Chinese Journal of Pediatrics have recently updated the "Guidelines for diagnosis and optimal management of asthma in children," first published in 2008...
December 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29221480/prevalence-and-etiologies-of-pulmonary-hypertension-in-africa-a-systematic-review-and-meta-analysis
#3
Jean Joel Bigna, Jean Jacques Noubiap, Jobert Richie Nansseu, Leopold Ndemnge Aminde
BACKGROUND: Despite the recent increasing worldwide attention towards pulmonary hypertension (PH), its epidemiology remains poorly described in Africa. Accordingly, we performed a systematic review and meta-analysis of PH prevalence, incidence and etiologies in Africa. METHODS: We searched PubMed, EMBASE, African Journals Online, and Africa Index Medicus. Published observational studies until September 20, 2017, including adult participants residing in Africa were considered...
December 8, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29217379/major-epidemiological-factors-associated-with-leptospirosis-in-malaysia
#4
REVIEW
Bashiru Garba, Abdul Rani Bahaman, Siti Khairani Bejo, Zunita Zakaria, Abdul Rahim Mutalib, Faruku Bande
INTRODUCTION: Leptospirosis is a zoonotic disease caused by a diverse pathogenic leptospira species and serovars. The disease is transmitted directly following contact with infected urine and other body fluids or indirectly after contact with water or soil contaminated with infected urine. OBJECTIVES: While a wide range of domestic and wild animals are known to be reservoirs of the disease, occupation, international travel and recreation are beginning to assume a center stage in the transmission of the disease...
February 2018: Acta Tropica
https://www.readbyqxmd.com/read/29188817/dietary-sugar-intake-was-associated-with-increased-body-fatness-but-decreased-cardiovascular-mortality-in-chinese-elderly-an-11-year-prospective-study-of-mr-and-ms-os-hong-kong
#5
Z-M Liu, S L A Tse, D Chan, C Wong, Sy-S Wong
BACKGROUND/OBJECTIVES: Epidemiological studies suggest that sugar intake contributes to weight gain and increased risk of cardiovascular diseases (CVD). However, this association is largely undefined in the elderly population. Our aim was to investigate the effect of sugar consumption on the subsequent changes in body fatness and CVD mortality in Chinese elderly. METHODS: A total of 2000 men and 2000 women aged ⩾65 years were recruited from 2001 to 2003. Dietary sugar intake was estimated based on a validated 329-item food frequency questionnaire and a local sugar database...
November 30, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29175884/epidemiology-of-obesity-and-overweight-in-sub-saharan-africa-a-protocol-for-a-systematic-review-and-meta-analysis
#6
Sibhatu Biadgilign, Tennyson Mgutshini, Demewoz Haile, Bereket Gebremichael, Yonatan Moges, Kelemu Tilahun
INTRODUCTION: Globally, overweight and obesity were estimated to cause 3.4 million deaths, 3.9% of years of life lost and 3.8% of disability-adjusted life years in 2010. Despite the fact that obesity and overweight is a problem of high-income countries, low- and middle-income countries (LMICs), in particular urban settings of sub-Saharan African countries, face the challenge of an increasing trend. The aim of this systematic review and meta-analysis will be to determine the prevalence of obesity and overweight individuals in sub-Saharan Africa and to help guide policy planners in the decision-making process for the increase in non-communicable diseases in Africa...
November 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/29151596/comparison-of-regional-fat-measurements-by-dual-energy-x-ray-absorptiometry-and-conventional-anthropometry-and-their-association-with-markers-of-diabetes-and-cardiovascular-disease-risk
#7
S K Vasan, C Osmond, D Canoy, C Christodoulides, M J Neville, C Di Gravio, C H D Fall, F Karpe
BACKGROUND/OBJECTIVE: Fat distribution is a strong and independent predictor of type 2 diabetes (T2D) and cardiovascular disease (CVD) and is usually determined using conventional anthropometry in epidemiological studies. Dual-energy X-ray absorptiometry (DXA) can measure total and regional adiposity more accurately. Nonetheless, whether DXA provides more precise estimates of cardiovascular risk in relation to total and regional adiposity is not known. We determined the strength of the associations between DXA- and conventional anthropometry determined fat distribution and T2D and CVD risk...
November 20, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29151594/adipocytes-sustain-pancreatic-cancer-progression-through-a-non-canonical-wnt-paracrine-network-inducing-ror2-nuclear-shuttling
#8
C Carbone, G Piro, N Gaianigo, F Ligorio, R Santoro, V Merz, F Simionato, C Zecchetto, G Falco, G Conti, P T Kamga, M Krampera, F Di Nicolantonio, L De Franceschi, A Scarpa, G Tortora, D Melisi
BACKGROUND: Solid epidemiological evidences connect obesity with incidence, stage, and survival in pancreatic cancer. However, the underlying mechanistic basis linking adipocytes to pancreatic cancer progression remain largely elusive. We hypothesized that factors secreted by adipocytes could be responsible for epithelial-to-mesenchymal transition (EMT) induction and, in turn, a more aggressive phenotype in models of pancreatic preneoplastic lesions. METHODS: We studied the role of factors secreted by two adipogenic model systems from primary human Bone Marrow Stromal Cells (hBMSC) in an in vitro experimental cell transformation model system of human pancreatic ductal epithelial (HPDE) cell stably expressing activated KRAS (HPDE/KRAS),RESULTS:We measured a significant induction of EMT and aggressiveness in HPDE and HPDE/KRAS cell lines when cultured with medium conditioned by fully differentiated adipocytes (ADIPO(CM)) if compared with the same cells cultured with medium conditioned by hBMSC (hBMSC(CM)) from two different healthy donors...
November 20, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29146647/initial-non-operative-management-of-uncomplicated-appendicitis-in-children-a-protocol-for-a-multicentre-randomised-controlled-trial-apac-trial
#9
Max Knaapen, Johanna H van der Lee, Roel Bakx, Sarah-May L The, Ernst W E van Heurn, Hugo A Heij, Ramon R Gorter
INTRODUCTION: Based on epidemiological, immunological and pathology data, the idea that appendicitis is not necessarily a progressive disease is gaining ground. Two types are distinguished: simple and complicated appendicitis. Non-operative treatment (NOT) of children with simple appendicitis has been investigated in several small studies. So far, it is deemed safe. However, its effectiveness and effect on quality of life (QoL) have yet to be established in an adequately powered randomised trial...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29064483/coupling-external-with-internal-exposure-metrics-of-trihalomethanes-in-young-females-from-kuwait-and-cyprus
#10
Stephanie Gängler, Konstantinos C Makris, Walid Bouhamra, Douglas W Dockery
The Eastern Mediterranean and the Middle Eastern regions are both understudied in terms of possible environmental health risks for their populations. Water scarcity and desalination treatment provide the general population of countries from these regions (e.g., Kuwait and Cyprus) with unique tap water characteristics. This study investigated the association between external (tap water and 24 h personal air samples) and internal (urine) THM exposure metrics that reflected information about THM-related habits and activities collected using questionnaires and time activity diaries...
October 18, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29061634/association-between-statistical-significance-and-time-to-publication-among-systematic-reviews-a-study-protocol-for-a-meta-epidemiological-investigation
#11
Yasushi Tsujimoto, Yusuke Tsutsumi, Yuki Kataoka, Hiraku Tsujimoto, Yosuke Yamamoto, Davide Papola, Gordon H Guyatt, Shunichi Fukuhara, Toshi A Furukawa
INTRODUCTION: Many studies have indicated the impact of bias in dissemination and publication in medical research. Existence of such bias among clinical trials has been repeatedly pointed out, but it has not been well studied in the field of systematic reviews (SRs). We therefore aim to investigate whether or not time lag bias and publication bias in SRs based on statistical significance in results exist. In addition, we will examine at what stage of paper publication process such bias, if any, creeps in...
October 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29019346/occupational-exposure-to-pesticides-development-of-a-job-exposure-matrix-for-use-in-population-based-studies-pestipop
#12
Camille Carles, Ghislaine Bouvier, Yolande Esquirol, Camille Pouchieu, Lucile Migault, Clément Piel, Pascale Fabbro-Peray, Séverine Tual, Pierre Lebailly, Isabelle Baldi
Occupational exposure to pesticides concerns a wide population of workers not only in agriculture. The reliability of self-reported information on pesticide use is questionable because of the diversity of use. The PESTIPOP job-exposure matrix has been designed to assess pesticide occupational exposure in the general population. The matrix is composed of two axes: the first axis corresponding to jobs (combinations of occupations and industries) and the second one to pesticide exposure. The estimated exposure metric is the probability of exposure coupled with a reliability assessment (low, medium or high)...
October 11, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29018068/epidemiology-of-venous-thromboembolism-in-africa-a-systematic-review-and-meta-analysis-protocol
#13
Celestin Danwang, Mazou N Temgoua, Valirie Ndip Agbor, Aurel T Tankeu, Jean Jacques Noubiap
INTRODUCTION: Venous thromboembolism (VTE) is among the three major causes of cardiovascular diseases worldwide after ischaemic heart disease and stroke. Knowledge on the global epidemiology of this condition is deficient in Africa. Accurate data are needed to evaluate the burden of VTE in Africa to design effective preventive and treatment strategies. This systematic review and meta-analysis aims to summarise epidemiological data on VTE in Africa and to evaluate the use of prophylaxis in African patients at risk of VTE...
October 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28990589/which-anthropometric-measures-best-reflect-neonatal-adiposity
#14
L-W Chen, M-T Tint, M V Fortier, I M Aris, Lp-C Shek, K H Tan, S-Y Chan, P D Gluckman, Y-S Chong, K M Godfrey, V S Rajadurai, F Yap, M S Kramer, Y S Lee
BACKGROUND: Studying the determinants and the long-term consequences of fetal adipose accretion requires accurate assessment of neonatal body composition. In large epidemiological studies, in-depth body composition measurement methods are usually not feasible for cost and logistical reasons, and there is a need to identify anthropometric measures that adequately reflect neonatal adiposity. METHODS: In a multiethnic Asian mother-offspring cohort in Singapore, anthropometric measures (weight, length, abdominal circumference, skinfold thicknesses) were measured using standardized protocols in newborn infants, and anthropometric indices [weight/length, weight/length(2) (body mass index, BMI), weight/length(3) (ponderal index, PI)] derived...
October 9, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28982825/detectaweb-project-study-protocol-of-a-web-based-detection-of-mental-health-of-children-and-adolescents
#15
Jose A Piqueras, Mariola Garcia-Olcina, Maria Rivera-Riquelme, Tiscar Rodriguez-Jimenez, Agustin E Martinez-Gonzalez, Pim Cuijpers
INTRODUCTION: Traditionally, research and practice addressing mental health has been conducted within a unidimensional model, explaining mental health as the presence/absence of psychological problems (distress or psychopathological symptoms). More recently, accumulative evidence has supported a bi-dimensional model, which conceptualises psychological problems and psychological strengths (well-being) as related-yet-distinct continua that, when considered together, yields a more comprehensive understanding of individuals...
October 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28963300/influence-of-allocation-concealment-and-intention-to-treat-analysis-on-treatment-effects-of-physical-therapy-interventions-in-low-back-pain-randomised-controlled-trials-a-protocol-of-a-meta-epidemiological-study
#16
Matheus Oliveira Almeida, Bruno T Saragiotto, Chris G Maher, Leonardo Oliveira Pena Costa
INTRODUCTION: Meta-epidemiological studies examining the influence of methodological characteristics, such as allocation concealment and intention-to-treat analysis have been performed in a large number of healthcare areas. However, there are no studies investigating these characteristics in physical therapy interventions for patients with low back pain. The aim of this study is to investigate the influence of allocation concealment and the use of intention-to-treat analysis on estimates of treatment effects of physical therapy interventions in low back pain clinical trials...
September 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28948026/design-of-the-subpopulations-and-intermediate-outcome-measures-in-copd-spiromics-air-study
#17
Nadia N Hansel, Laura M Paulin, Amanda J Gassett, Roger D Peng, Neil Alexis, Vincent S Fan, Eugene Bleecker, Russell Bowler, Alejandro P Comellas, Mark Dransfield, MeiLan K Han, Victor Kim, Jerry A Krishnan, Cheryl Pirozzi, Christopher B Cooper, Fernando Martinez, Prescott G Woodruff, Patrick J Breysse, R Graham Barr, Joel D Kaufman
INTRODUCTION: Population-based epidemiological evidence suggests that exposure to ambient air pollutants increases hospitalisations and mortality from chronic obstructive pulmonary disease (COPD), but less is known about the impact of exposure to air pollutants on patient-reported outcomes, morbidity and progression of COPD. METHODS AND ANALYSIS: The Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air Pollution Study (SPIROMICS AIR) was initiated in 2013 to investigate the relation between individual-level estimates of short-term and long-term air pollution exposures, day-to-day symptom variability and disease progression in individuals with COPD...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28932373/cohort-profile-update-the-amirkola-health-and-ageing-project-ahap
#18
Ali Bijani, Reza Ghadimi, Ebrahim Mikaniki, Farzan Kheirkhah, Seyyed Ali Mozaffarpur, Mina Motallebnejad, Haleh Esmaili, Fatemeh Majidi, Robert Graham Cumming, Seyed Reza Hosseini
The original cohort study of AHAP started in 2011 on 1616 elderly residents of Amirkola, northern part of Iran near the Caspian Sea. The main goal of this study was to comprehensively evaluate the health of the elderly in the region with the emphasis on chronic diseases such as osteoporosis. The first cohort profile was published in the International Journal of Epidemiology in 2014. The phase 1 AHAP showed the elevated level of some diseases and conditions including osteoporosis, metabolic syndrome, obesity, vision problems and relatively low levels of oral health...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28883539/role-of-adipose-tissue-in-melanoma-cancer-microenvironment-and-progression
#19
E Zoico, E Darra, V Rizzatti, M Tebon, G Franceschetti, G Mazzali, A P Rossi, F Fantin, M Zamboni
BACKGROUND: An epidemiological association between excess weight and increased risk of cancer has been described in melanoma, for which the physiopathological mechanisms are still unknown. The study of tumor microenvironment and of the role of adipocytes in cancer development, progression and metastasis has recently received great interest. However, the role of peritumoral adipocytes has been characterized only in a few types of cancer and in melanoma it still remains to be defined. METHODS: We investigated the interactions between adipocytes and melanoma cells using an in vitro co-culture system...
September 8, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28863029/requirements-for-trial-registration-and-adherence-to-reporting-guidelines-in-critical-care-journals-a-meta-epidemiological-study-of-journals-instructions-for-authors
#20
Matthew T Sims, Jake X Checketts, Cole Wayant, Matt Vassar
BACKGROUND: The purpose of this study was to investigate the policies of critical care journals with regard to guideline adoption and clinical trial registration to understand the extent to which journals use these mechanisms to improve reporting practices. METHODS: The current study's sample comprised 37 critical care journals cataloged in the Expanded Science Citation Index of the 2015 Journal Citation Reports and Google Scholar Metrics h5-index critical care subcategory...
August 31, 2017: International Journal of Evidence-based Healthcare
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