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https://www.readbyqxmd.com/read/28068594/prevention-of-spontaneous-preterm-birth-guidelines-for-clinical-practice-from-the-french-college-of-gynaecologists-and-obstetricians-cngof
#1
REVIEW
Loïc Sentilhes, Marie-Victoire Sénat, Pierre-Yves Ancel, Elie Azria, Guillaume Benoist, Julie Blanc, Gilles Brabant, Florence Bretelle, Stéphanie Brun, Muriel Doret, Chantal Ducroux-Schouwey, Anne Evrard, Gilles Kayem, Emeline Maisonneuve, Louis Marcellin, Stéphane Marret, Nicolas Mottet, Sabine Paysant, Didier Riethmuller, Patrick Rozenberg, Thomas Schmitz, Héloïse Torchin, Bruno Langer
In France, 60,000 neonates are born preterm every year (7.4%), half of them after the spontaneous onset of labor. Among preventable risk factors of spontaneous prematurity, only cessation of smoking is associated with decreased prematurity (level of evidence [LE]1). It is therefore recommended (Grade A). Routine screening and treatment of vaginal bacteriosis is not recommended in the general population (Grade A). The only population for which vaginal progesterone is recommended is that comprising asymptomatic women with singleton pregnancies, no history of preterm delivery, and a short cervix at 16-24 weeks of gestation (Grade B)...
December 30, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28029461/-prevention-of-preterm-birth-by-uterine-cervical-cerclage
#2
L Marcellin
OBJECTIVE: To review the scientific literature on cervical insufficiency and indications of cervical cerclage cervix. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and international obstetrical societies between 1972 and June 2016 have been consulted. RESULTS: Cervical insufficiency is a pathophysiological concept and to date no consensual definition is available: the diagnosis is clinical and discussed retrospectively in case of patients with a history of late miscarriages and/or spontaneous preterm delivery, with asymptomatic dilatation of the cervix (professional consensus)...
October 29, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27958622/comparison-of-two-different-antibiotic-regimens-for-the-prophylaxisis-of-cases-with-preterm-premature-rupture-of-membranes-a-randomized-clinical-trial
#3
Ilker Kahramanoglu, Merve Baktiroglu, Taylan Senol, Ozge Kahramanoglu, Enis Ozkaya, Olcay Ilhan, Fatma Ferda Verit, Seyda Baydogan, Oguz Yucel
OBJECTIVES: The aim of the study was to assess the effect of 1 g ampicillin prophylactic dosage whether it is as effective as the dosage of 2 g to prevent maternal and neonatal morbidity in a randomized manner. MATERIALS AND METHODS: One hundred and fourty eight singleton pregnant women with preterm premature rupture of membranes between 21 and 33 weeks of gestation were followed-up during the study period in our institution. We com-pared the efficacy of two different different dosages of ampicillin...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27836377/-prevention-of-spontaneous-preterm-birth-excluding-preterm-premature-rupture-of-membranes-guidelines-for-clinical-practice%C3%A2-%C3%A2-text-of-the-guidelines-short-text
#4
L Sentilhes, M-V Sénat, P-Y Ancel, E Azria, G Benoist, J Blanc, G Brabant, F Bretelle, S Brun, M Doret, C Ducroux-Schouwey, A Evrard, G Kayem, E Maisonneuve, L Marcellin, S Marret, N Mottet, S Paysant, D Riethmuller, P Rozenberg, T Schmitz, H Torchin, B Langer
OBJECTIVES: To determine the measures to prevent spontaneous preterm birth (excluding preterm premature rupture of membranes)and its consequences. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: In France, premature birth concerns 60,000 neonates every year (7.4 %), half of them are delivered after spontaneous onset of labor...
December 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27825282/relationship-between-maternal-c-reactive-protein-level-and-neonatal-outcome-in-patients-with-preterm-premature-rupture-of-membranes-treated-with-ampicillin-and-azithromycin
#5
Mehmet Serdar Kutuk, Osman Bastug, Ahmet Ozdemir, Mehmet Adnan Ozturk, Mahmut Tuncay Ozgun, Mustafa Basbug, Tamer Gunes, Selim Kurtoglu
This historical cohort study aimed to assess the relationship between antenatal maternal C-reactive protein (CRP) level and neonatal outcome preterm premature rupture of membranes (PPROM). We reviewed the records of 70 singleton pregnancies with PPROM between 24 and 34 weeks. Maternal CRP levels of neonates with respiratory distress syndrome, neonatal sepsis, grade 3-4 intraventricular haemorrhage and stage 2-3 necrotizing enterocolitis, perinatal mortality were compared with those without these complications...
August 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27744438/vaginal-probiotic-administration-in-the-management-of-preterm-premature-rupture-of-membranes
#6
George J Daskalakis, Alexis K Karambelas
OBJECTIVE: To examine the influence of vaginal probiotic administration as an adjunct to standard antibiotic treatment on perinatal outcome in women with preterm premature rupture of membranes (PPROM). MATERIALS AND METHODS: This was a prospective randomized trial of cases with PPROM (24-34 weeks) that were admitted to our department between 2011 and 2015. Forty-nine cases received vaginal probiotics for 10 days in combination with antibiotic prophylaxis and were compared to 57 others that received only antibiotics for the same time period...
October 15, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27687157/comparison-of-antibiotic-regimens-in-preterm-premature-rupture-of-membranes-neonatal-morbidity-and-2-year-follow-up-of-neurologic-outcome
#7
Kylie Hae-Jin Chang, Hyun-Joo Kim, Hee Joon Yu, Jeehun Lee, Jung-Sun Kim, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh, Jong-Hwa Kim
OBJECTIVES: The objective of this study was to compare neonatal morbidity and neurologic outcome at 2 years between groups treated with antibiotics regimens consisting clarithromycin and erythromycin in preterm premature rupture of the membranes (pPROM) patients delivered before 32 weeks of gestation. METHODS: This was a retrospective study comparing neonatal morbidity as primary outcome measures and the neurological outcome at 2 years as secondary outcome. RESULTS: A total of 166 women were included: 80 treated with erythromycin and 86 treated with clarithromycin...
October 20, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27593156/an-area-based-study-on-intrapartum-antibiotic-prophylaxis-for-preventing-group-b-streptococcus-early-onset-disease-advances-and-limitations
#8
Alberto Berardi, Cecilia Rossi, Maria Letizia Bacchi Reggiani, Annalisa Bastelli, Maria Grazia Capretti, Claudio Chiossi, Valentina Fiorini, Lucia Gambini, Sara Gavioli, Marcello Lanari, Luigi Memo, Irene Papa, Luana Pini, Maria Vittoria Rizzo, Andrea Zucchini, Fabio Facchinetti, Fabrizio Ferrari
INTRODUCTION: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking. MATERIALS AND METHODS: This was a 3-month retrospective area-based study including all regional deliveries  ≥35 weeks' gestation (in 2012). The sensitivity, specificity, positive and negative predictive values, odds ratio and receiver operating characteristic (ROC) curve for intrapartum antibiotic prophylaxis (IAP) among full-term and preterm deliveries and prolonged membrane rupture (PROM) were calculated...
September 5, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27551580/prophylactic-antibiotics-in-twin-pregnancies-complicated-by-previable-preterm-premature-rupture-of-membranes
#9
Olivia Myrick, Sarah Dotters-Katz, Matthew Grace, Tracy Manuck, Kim Boggess, William Goodnight
OBJECTIVE: This study aims to determine if antibiotics given for latency to women with twins and previable preterm premature rupture of membranes (PPROM) affect the duration from membrane rupture to delivery. METHODS: A retrospective cohort study of twin pregnancies at a single center from 2000 to 2015 with previable (14 (0/7)-22 (6/7) weeks) PPROM was conducted. Women who were not candidates for expectant management or who elected for immediate delivery were excluded...
July 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27510868/-an-analysis-of-181-cases-with-blood-stream-infection-caused-by-streptococcus-agalactiae-in-children-from-2011-to-2015-a-multi-center-retrospective-study
#10
C Z Hua, H Yu, J Q Zhuang, X L Li, H M Xu, Q E Luo, H P Lu, H M Yu, Y Cao, Y P Chen, T Zhang, C M Jing, L Z Du, C Q Wang, Z L Lin, H Zhang, X J Chen, Z Y Hua
OBJECTIVE: To analyze the clinical characteristics of blood stream infection caused by Streptococcus agalactiae in children and the drug-resistance of the isolates. METHOD: All cases with Streptococcus agalactiae growth in blood or cerebrospinal fluid cultures from January 1, 2011 to December 31, 2015 were enrolled by checking the laboratory information system (LIS) from 7 Class 3 Grade A hospitals (4 in Zhejiang, 2 in Shanghai and 1 in Chongqing). Clinical data were collected for analysis...
August 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27436434/staphylococcus-aureus-infection-of-human-gestational-membranes-induces-bacterial-biofilm-formation-and-host-production-of-cytokines
#11
Ryan S Doster, Leslie A Kirk, Lauren M Tetz, Lisa M Rogers, David M Aronoff, Jennifer A Gaddy
Staphylococcus aureus, a metabolically flexible gram-positive pathogen, causes infections in a variety of tissues. Recent evidence implicates S. aureus as an emerging cause of chorioamnionitis and premature rupture of membranes, which are associated with preterm birth and neonatal disease. We demonstrate here that S. aureus infects and forms biofilms on the choriodecidual surface of explanted human gestational membranes. Concomitantly, S. aureus elicits the production of proinflammatory cytokines, which could ultimately perturb maternal-fetal tolerance during pregnancy...
July 19, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27401661/prevalence-and-antibiotic-susceptibility-of-mycoplasma-hominis-and-ureaplasma-urealyticum-in-pregnant-women
#12
Min Young Lee, Myeong Hee Kim, Woo In Lee, So Young Kang, You La Jeon
Mycoplasma hominis (M. hominis) and Ureaplasma urealyticum (U. urealyticum) are important opportunistic pathogens that cause urogenital infections and complicate pregnancy. The aim of this study was to investigate the prevalence, effects on pregnancy outcomes, and antimicrobial susceptibilities of M. hominis and U. urealyticum. We tested vaginal swabs obtained from 1035 pregnant women for the presence of genital mycoplasmas between June 2009 and May 2014. The laboratory and clinical aspects of genital mycoplasmas infection were reviewed retrospectively, and the identification and antimicrobial susceptibility of genital mycoplasmas were determined using the Mycoplasma IST-2 kit...
September 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27280063/the-effect-of-a-universal-cervical-length-screening-program-on-antepartum-management-and-birth-outcomes
#13
Scott A Shainker, Anna M Modest, Michele R Hacker, Steven J Ralston
Objective The objective of this study was to evaluate the effect of a universal cervical length screening program on the incidence of antepartum interventions. Study Design This retrospective cohort study included women delivering ≥ 20 weeks of gestation with singleton pregnancies before and after implementing universal cervical length screening. Antepartum interventions included admission for threatened preterm birth, ≥ 2 cervical length measurements, cervical cerclage, neonatology consultation, betamethasone, antibiotic administration for preterm premature rupture of membranes, and tocolysis...
April 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27214190/obstetric-care-consensus-no-4-periviable-birth
#14
(no author information available yet)
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
June 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27214184/obstetric-care-consensus-no-4-summary-periviable-birth
#15
(no author information available yet)
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
June 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27137630/increased-risk-of-early-onset-neonatal-sepsis-after-laser-surgery-for-twin-to-twin-transfusion-syndrome
#16
Liselotte E M van Kempen, Depeng Zhao, Sylke J Steggerda, Vincent Bekker, Johanna M Middeldorp, Dick Oepkes, Enrico Lopriore
OBJECTIVE: To investigate the occurrence of early-onset neonatal sepsis (EOS) in twin-twin transfusion syndrome (TTTS) managed with laser surgery. STUDY DESIGN: We performed a prospective cohort study of all consecutive TTTS cases treated with laser surgery (TTTS group) delivered at the Leiden University Medical Center. We recorded the occurrence of EOS, defined as a positive blood culture ≤72 hours postpartum (proven sepsis) or administration of a full course of antibiotics due to risk factors or signs of sepsis, in the absence of a positive blood culture (suspected sepsis)...
June 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/27103153/periviable-birth-interim-update
#17
Jeffrey L Ecker, Anjali Kaimal, Brian M Mercer, Sean C Blackwell, Raye Ann O deRegnier, Ruth M Farrell, William A Grobman, Jamie L Resnik, Anthony C Sciscione
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
August 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27054940/cervical-cerclage-during-periviability-can-we-stabilize-a-moving-target
#18
Joshua D Dahlke, Jeffrey D Sperling, Suneet P Chauhan, Vincenzo Berghella
The American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine recently published consensus guidelines on periviable birth recommending that obstetric interventions (antenatal corticosteroids, tocolysis, magnesium sulfate, antibiotics for preterm premature rupture of membranes or group B streptococcus prophylaxis, and cesarean delivery for fetal indications) may be considered at 23 0/7 weeks of gestation and neonatal resuscitation at 22 0/7 weeks of gestation. Cervical cerclage significantly decreases preterm delivery and improves perinatal outcomes in women with a singleton pregnancy, prior spontaneous preterm birth, and transvaginal cervical length less than 25 mm before 24 0/7 weeks of gestation or in women who experience painless cervix dilation in the second trimester...
May 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26875954/antepartum-and-intrapartum-interventions-to-prevent-preterm-birth-and-its-sequelae
#19
REVIEW
T A J Nijman, E O G van Vliet, B Koullali, B W Mol, M A Oudijk
Preterm birth is the main cause of neonatal morbidity and mortality. This review provides an overview of antepartum and intrapartum management of threatened preterm birth. The most effective method to identify women at high risk of delivering within seven days is the combination of cervical length and fetal fibronectin test. Antenatal corticosteroids administered for 48 h improve neonatal outcome. Although tocolysis has been shown to prolong pregnancy, there is no evidence that tocolytic therapy improves neonatal outcomes...
April 2016: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/26831896/neonatal-and-maternal-outcomes-following-midtrimester-preterm-premature-rupture-of-the-membranes-a-retrospective-cohort-study
#20
Laura Aoife Linehan, Jennifer Walsh, Aoife Morris, Louise Kenny, Keelin O'Donoghue, Eugene Dempsey, Noirin Russell
BACKGROUND: Preterm premature rupture of membranes (PPROM) complicates 1% of all pregnancies and occurs in one third of all preterm deliveries. Midtrimester PPROM is often followed by spontaneous miscarriage and elective termination of ongoing pregnancies is offered in many countries. The aim of this retrospective descriptive cohort study was to investigate the natural history of midtrimester PPROM in a jurisdiction where termination of pregnancy in the absence of maternal compromise is unavailable...
2016: BMC Pregnancy and Childbirth
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