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preterm prom antibiotic

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https://www.readbyqxmd.com/read/27836377/-prevention-of-spontaneous-preterm-birth-excluding-preterm-premature-rupture-of-membranes-guidelines-for-clinical-practice%C3%A2-%C3%A2-text-of-the-guidelines-short-text
#1
L Sentilhes, M-V Sénat, P-Y Ancel, E Azria, G Benoist, J Blanc, G Brabant, F Bretelle, S Brun, M Doret, C Ducroux-Schouwey, A Evrard, G Kayem, E Maisonneuve, L Marcellin, S Marret, N Mottet, S Paysant, D Riethmuller, P Rozenberg, T Schmitz, H Torchin, B Langer
OBJECTIVES: To determine the measures to prevent spontaneous preterm birth (excluding preterm premature rupture of membranes)and its consequences. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: In France, premature birth concerns 60,000 neonates every year (7.4 %), half of them are delivered after spontaneous onset of labor...
November 8, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27825282/relationship-between-maternal-c-reactive-protein-level-and-neonatal-outcome-in-patients-with-preterm-premature-rupture-of-membranes-treated-with-ampicillin-and-azithromycin
#2
Mehmet Serdar Kutuk, Osman Bastug, Ahmet Ozdemir, Mehmet Adnan Ozturk, Mahmut Tuncay Ozgun, Mustafa Basbug, Tamer Gunes, Selim Kurtoglu
This historical cohort study aimed to assess the relationship between antenatal maternal C-reactive protein (CRP) level and neonatal outcome preterm premature rupture of membranes (PPROM). We reviewed the records of 70 singleton pregnancies with PPROM between 24 and 34 weeks. Maternal CRP levels of neonates with respiratory distress syndrome, neonatal sepsis, grade 3-4 intraventricular haemorrhage and stage 2-3 necrotizing enterocolitis, perinatal mortality were compared with those without these complications...
August 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27744438/vaginal-probiotic-administration-in-the-management-of-preterm-premature-rupture-of-membranes
#3
George J Daskalakis, Alexis K Karambelas
OBJECTIVE: To examine the influence of vaginal probiotic administration as an adjunct to standard antibiotic treatment on perinatal outcome in women with preterm premature rupture of membranes (PPROM). MATERIALS AND METHODS: This was a prospective randomized trial of cases with PPROM (24-34 weeks) that were admitted to our department between 2011 and 2015. Forty-nine cases received vaginal probiotics for 10 days in combination with antibiotic prophylaxis and were compared to 57 others that received only antibiotics for the same time period...
October 15, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27687157/comparison-of-antibiotic-regimens-in-preterm-premature-rupture-of-membranes-neonatal-morbidity-and-2-year-follow-up-of-neurologic-outcome
#4
Kylie Hae-Jin Chang, Hyun-Joo Kim, Hee Joon Yu, Jeehun Lee, Jung-Sun Kim, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh, Jong-Hwa Kim
OBJECTIVES: The objective of this study was to compare neonatal morbidity and neurologic outcome at 2 years between groups treated with antibiotics regimens consisting clarithromycin and erythromycin in preterm premature rupture of the membranes (pPROM) patients delivered before 32 weeks of gestation. METHODS: This was a retrospective study comparing neonatal morbidity as primary outcome measures and the neurological outcome at 2 years as secondary outcome. RESULTS: A total of 166 women were included: 80 treated with erythromycin and 86 treated with clarithromycin...
October 20, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27593156/an-area-based-study-on-intrapartum-antibiotic-prophylaxis-for-preventing-group-b-streptococcus-early-onset-disease-advances-and-limitations
#5
Alberto Berardi, Cecilia Rossi, Maria Letizia Bacchi Reggiani, Annalisa Bastelli, Maria Grazia Capretti, Claudio Chiossi, Valentina Fiorini, Lucia Gambini, Sara Gavioli, Marcello Lanari, Luigi Memo, Irene Papa, Luana Pini, Maria Vittoria Rizzo, Andrea Zucchini, Fabio Facchinetti, Fabrizio Ferrari
INTRODUCTION: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking. MATERIALS AND METHODS: This was a 3-month retrospective area-based study including all regional deliveries  ≥35 weeks' gestation (in 2012). The sensitivity, specificity, positive and negative predictive values, odds ratio and receiver operating characteristic (ROC) curve for intrapartum antibiotic prophylaxis (IAP) among full-term and preterm deliveries and prolonged membrane rupture (PROM) were calculated...
September 5, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27551580/prophylactic-antibiotics-in-twin-pregnancies-complicated-by-previable-preterm-premature-rupture-of-membranes
#6
Olivia Myrick, Sarah Dotters-Katz, Matthew Grace, Tracy Manuck, Kim Boggess, William Goodnight
OBJECTIVE: This study aims to determine if antibiotics given for latency to women with twins and previable preterm premature rupture of membranes (PPROM) affect the duration from membrane rupture to delivery. METHODS: A retrospective cohort study of twin pregnancies at a single center from 2000 to 2015 with previable (14 (0/7)-22 (6/7) weeks) PPROM was conducted. Women who were not candidates for expectant management or who elected for immediate delivery were excluded...
July 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27510868/-an-analysis-of-181-cases-with-blood-stream-infection-caused-by-streptococcus-agalactiae-in-children-from-2011-to-2015-a-multi-center-retrospective-study
#7
C Z Hua, H Yu, J Q Zhuang, X L Li, H M Xu, Q E Luo, H P Lu, H M Yu, Y Cao, Y P Chen, T Zhang, C M Jing, L Z Du, C Q Wang, Z L Lin, H Zhang, X J Chen, Z Y Hua
OBJECTIVE: To analyze the clinical characteristics of blood stream infection caused by Streptococcus agalactiae in children and the drug-resistance of the isolates. METHOD: All cases with Streptococcus agalactiae growth in blood or cerebrospinal fluid cultures from January 1, 2011 to December 31, 2015 were enrolled by checking the laboratory information system (LIS) from 7 Class 3 Grade A hospitals (4 in Zhejiang, 2 in Shanghai and 1 in Chongqing). Clinical data were collected for analysis...
August 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27436434/staphylococcus-aureus-infection-of-human-gestational-membranes-induces-bacterial-biofilm-formation-and-host-production-of-cytokines
#8
Ryan S Doster, Leslie A Kirk, Lauren M Tetz, Lisa M Rogers, David M Aronoff, Jennifer A Gaddy
Staphylococcus aureus, a metabolically flexible gram-positive pathogen, causes infections in a variety of tissues. Recent evidence implicates S. aureus as an emerging cause of chorioamnionitis and premature rupture of membranes, which are associated with preterm birth and neonatal disease. We demonstrate here that S. aureus infects and forms biofilms on the choriodecidual surface of explanted human gestational membranes. Concomitantly, S. aureus elicits the production of proinflammatory cytokines, which could ultimately perturb maternal-fetal tolerance during pregnancy...
July 19, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27401661/prevalence-and-antibiotic-susceptibility-of-mycoplasma-hominis-and-ureaplasma-urealyticum-in-pregnant-women
#9
Min Young Lee, Myeong Hee Kim, Woo In Lee, So Young Kang, You La Jeon
Mycoplasma hominis (M. hominis) and Ureaplasma urealyticum (U. urealyticum) are important opportunistic pathogens that cause urogenital infections and complicate pregnancy. The aim of this study was to investigate the prevalence, effects on pregnancy outcomes, and antimicrobial susceptibilities of M. hominis and U. urealyticum. We tested vaginal swabs obtained from 1035 pregnant women for the presence of genital mycoplasmas between June 2009 and May 2014. The laboratory and clinical aspects of genital mycoplasmas infection were reviewed retrospectively, and the identification and antimicrobial susceptibility of genital mycoplasmas were determined using the Mycoplasma IST-2 kit...
December 0: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27280063/the-effect-of-a-universal-cervical-length-screening-program-on-antepartum-management-and-birth-outcomes
#10
Scott A Shainker, Anna M Modest, Michele R Hacker, Steven J Ralston
Objective The objective of this study was to evaluate the effect of a universal cervical length screening program on the incidence of antepartum interventions. Study Design This retrospective cohort study included women delivering ≥ 20 weeks of gestation with singleton pregnancies before and after implementing universal cervical length screening. Antepartum interventions included admission for threatened preterm birth, ≥ 2 cervical length measurements, cervical cerclage, neonatology consultation, betamethasone, antibiotic administration for preterm premature rupture of membranes, and tocolysis...
April 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27214190/obstetric-care-consensus-no-4-periviable-birth
#11
(no author information available yet)
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
June 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27214184/obstetric-care-consensus-no-4-summary-periviable-birth
#12
(no author information available yet)
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
June 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27137630/increased-risk-of-early-onset-neonatal-sepsis-after-laser-surgery-for-twin-to-twin-transfusion-syndrome
#13
Liselotte E M van Kempen, Depeng Zhao, Sylke J Steggerda, Vincent Bekker, Johanna M Middeldorp, Dick Oepkes, Enrico Lopriore
OBJECTIVE: To investigate the occurrence of early-onset neonatal sepsis (EOS) in twin-twin transfusion syndrome (TTTS) managed with laser surgery. STUDY DESIGN: We performed a prospective cohort study of all consecutive TTTS cases treated with laser surgery (TTTS group) delivered at the Leiden University Medical Center. We recorded the occurrence of EOS, defined as a positive blood culture ≤72 hours postpartum (proven sepsis) or administration of a full course of antibiotics due to risk factors or signs of sepsis, in the absence of a positive blood culture (suspected sepsis)...
June 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/27103153/periviable-birth-interim-update
#14
Jeffrey L Ecker, Anjali Kaimal, Brian M Mercer, Sean C Blackwell, Raye Ann O deRegnier, Ruth M Farrell, William A Grobman, Jamie L Resnik, Anthony C Sciscione
Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks to 25 6/7 weeks of gestation. When delivery is anticipated near the limit of viability, families and health care teams are faced with complex and ethically challenging decisions. Multiple factors have been found to be associated with short-term and long-term outcomes of periviable births in addition to gestational age at birth...
August 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27054940/cervical-cerclage-during-periviability-can-we-stabilize-a-moving-target
#15
Joshua D Dahlke, Jeffrey D Sperling, Suneet P Chauhan, Vincenzo Berghella
The American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine recently published consensus guidelines on periviable birth recommending that obstetric interventions (antenatal corticosteroids, tocolysis, magnesium sulfate, antibiotics for preterm premature rupture of membranes or group B streptococcus prophylaxis, and cesarean delivery for fetal indications) may be considered at 23 0/7 weeks of gestation and neonatal resuscitation at 22 0/7 weeks of gestation. Cervical cerclage significantly decreases preterm delivery and improves perinatal outcomes in women with a singleton pregnancy, prior spontaneous preterm birth, and transvaginal cervical length less than 25 mm before 24 0/7 weeks of gestation or in women who experience painless cervix dilation in the second trimester...
May 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26875954/antepartum-and-intrapartum-interventions-to-prevent-preterm-birth-and-its-sequelae
#16
REVIEW
T A J Nijman, E O G van Vliet, B Koullali, B W Mol, M A Oudijk
Preterm birth is the main cause of neonatal morbidity and mortality. This review provides an overview of antepartum and intrapartum management of threatened preterm birth. The most effective method to identify women at high risk of delivering within seven days is the combination of cervical length and fetal fibronectin test. Antenatal corticosteroids administered for 48 h improve neonatal outcome. Although tocolysis has been shown to prolong pregnancy, there is no evidence that tocolytic therapy improves neonatal outcomes...
April 2016: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/26831896/neonatal-and-maternal-outcomes-following-midtrimester-preterm-premature-rupture-of-the-membranes-a-retrospective-cohort-study
#17
Laura Aoife Linehan, Jennifer Walsh, Aoife Morris, Louise Kenny, Keelin O'Donoghue, Eugene Dempsey, Noirin Russell
BACKGROUND: Preterm premature rupture of membranes (PPROM) complicates 1% of all pregnancies and occurs in one third of all preterm deliveries. Midtrimester PPROM is often followed by spontaneous miscarriage and elective termination of ongoing pregnancies is offered in many countries. The aim of this retrospective descriptive cohort study was to investigate the natural history of midtrimester PPROM in a jurisdiction where termination of pregnancy in the absence of maternal compromise is unavailable...
2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/26644969/persistent-microbial-dysbiosis-in-preterm-premature-rupture-of-membranes-from-onset-until-delivery
#18
Elizabeth A Baldwin, Marina Walther-Antonio, Allison M MacLean, Daryl M Gohl, Kenneth B Beckman, Jun Chen, Bryan White, Douglas J Creedon, Nicholas Chia
Background. Preterm Premature Rupture of Membranes (PPROM) is a major leading cause of preterm births. While the cause for PPROM remains unidentified, it is anticipated to be due to subclinical infection, since a large proportion of PPROM patients display signs of chorioamnionitis. Since subclinical infections can be facilitated by dysbiosis, our goal was to characterize the vaginal microbiome and amniotic fluid discharge upon PPROM, through latency antibiotic treatment, and until delivery, to detect the presence of pathogens, microbiota alteration, and microbial response to treatment...
2015: PeerJ
https://www.readbyqxmd.com/read/26605446/is-preterm-premature-rupture-of-membranes-latency-influenced-by-single-versus-multiple-agent-antibiotic-prophylaxis-in-group-b-streptococcus-positive-women-delivering-preterm
#19
COMPARATIVE STUDY
Anita Smith, Victoria M Allen, Jennifer Walsh, Krista Jangaard, Colleen M O'Connell
OBJECTIVE: To evaluate the influence of antibiotic regimen on the duration of latency (time from preterm pre-labour rupture of membranes [PPROM] to delivery) and significant infectious neonatal morbidity from rupture of membranes to delivery < 37 weeks' gestational age in women known to be group B Streptococcus (GBS) positive. METHODS: We obtained data from the Nova Scotia Atlee Perinatal Database. In a retrospective, cohort, population-based study, we included pregnancies complicated by PPROM but excluded pregnancies in this group requiring immediate delivery...
September 2015: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/26527114/the-postnatal-morbidity-associated-with-second-trimester-miscarriage
#20
Aoife Morris, Sarah Meaney, Niamh Spillane, Keelin O'Donoghue
OBJECTIVE(S): To describe the complications, and their incidence, associated with the management and delivery of a distinct second-trimester miscarriage cohort. METHODS: A retrospective cohort study was undertaken in a large, tertiary-referral university hospital (8500 deliveries per annum). All cases of pregnancy loss occurring between 14(+0) and 23(+6) were identified from July 2009 to June 2013 (n = 181). Medical notes were reviewed and the number of complications among this cohort was identified...
November 3, 2015: Journal of Maternal-fetal & Neonatal Medicine
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