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Pregnancy Cardiology

Kara N Durski, Carol Tituli, Divi Ogaoga, Jennie Musto, Cynthia Joshua, Alfred Dofai, Jennie Leydon, Eric Nilles
INTRODUCTION: During May 2012, a rubella outbreak was declared in Solomon Islands. A suspected case of congenital rubella syndrome (CRS) was reported from one hospital 11 months later in 2013. This report describes the subsequent CRS investigation, findings and measures implemented. METHODS: Prospective CRS surveillance was conducted at the newborn nursery, paediatric and post-natal wards, and the paediatric cardiology and ophthalmology clinics of the study hospital from April to July 2013...
January 2016: Western Pacific Surveillance and Response Journal: WPSAR
Rubab Munir, Sajjad Hussain, Azhar Mahmood Kayani
OBJECTIVE: To describe the demographics, risk factors, and clinical presentation in Pakistani patients with peripartum cardiomyopathy. STUDY DESIGN: A descriptive observational study. PLACE AND DURATION OF STUDY: Rawalpindi Institute of Cardiology, Rawalpindi, from June 2014 to June 2015. METHODOLOGY: Seventy patients meeting criteria of peripartum cardiomyopathy were included in the study. Adetailed history, physical examination and investigations were done...
September 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Nicla A Varnier, Franzisca Pettit, David Rees, Steven Thou, Mark Brown, Amanda Henry
BACKGROUND: Cardiovascular disease affects 0.2-4% of pregnancies. Coupled with the physiological stress of pregnancy, cardiovascular disease may present significant management challenges including appropriate risk:benefit analysis of medical and surgical management options. CASE: A 33-year-old gravida 4 para 1 miscarriage 2 presented at 18 weeks' gestation to the high-risk pregnancy service with a history of coronary artery disease and homozygous familial hypercholesterolaemia...
September 2015: Obstetric Medicine
Magdalena Barlik, Agnieszka Seremak-Mrozikiewicz, Krzysztof Drews, Andrzej Klejewski, Grażyna Kurzawińska, Zdzisław Łowicki, Hubert Wolski
BACKGROUND: Polymorphisms which are presented below may be the cause of inherited thrombophilia and may result in pregnancy loss. The hypothesis is based on a number of cardiology studies which have confirmed the involvement of these polymorphisms in thrombotic incidents. OBJECTIVES: To evaluate the role of polymorphisms of factor VII gene (Arg353Gln, -122T > C) and PAI-1 gene (-675 4G/5G) in the etiology of recurrent miscarriage. MATERIAL AND METHODS: The study group included 152 women with a positive history of ≥ 2 consecutive pregnancy losses (114 and 38 women with 2 and ≥ 3 miscarriages, respectively), while 180 healthy women were recruited as controls...
2016: Ginekologia Polska
Senbeta Guteta, Dejuma Yadeta, Aklilu Azazh, Dufera Mekonnen
BACKGROUND: Valvular heart disease has been a significant cause of heart disease worldwide. In Ethiopia, it particularly affects young individuals and constitutes the major cause of cardiovascular disease. Factors associated with choice of treatment for advanced valvular heart disease are variable. The objective of this study is to review surgery done for Ethiopian patients with valvular heart disease. METHODS: We analyzed data on patients who had valve surgery and follow-up at the Tikur Anbessa Specialized Hospital cardiology unit...
April 2016: Ethiopian Medical Journal
Claire Mounier-Vehier, Jacques Amar, Jean-Marc Boivin, Thierry Denolle, Jean-Pierre Fauvel, Geneviève Plu-Bureau, Vassilis Tsatsaris, Jacques Blacher
High blood pressure in pregnancy remains, by its complications, the leading cause of morbidity and maternal and fetal mortality. The frequency (5 to 10% of pregnancies) and the potential severity of this disease, both for mother and child, encourage to standardize and to optimize our medical practices. This is the main objective of this work. If the short-term complications for the mother and child are well known, long-term ones for the mother beginning to be better identified (in particular, the risk of recurrence in a subsequent pregnancy, the risk of chronic hypertension and the increased risk of cardiovascular events)...
July 2016: La Presse Médicale
Karen Sliwa, Iris M van Hagen, Werner Budts, Lorna Swan, Gianfranco Sinagra, Maryanne Caruana, Manuel Vazquez Blanco, Lodewijk J Wagenaar, Mark R Johnson, Gary Webb, Roger Hall, Jolien W Roos-Hesselink
AIMS: To describe the outcomes of pregnancy in women with pulmonary hypertension. METHODS AND RESULTS: In 2007 the European Registry on Pregnancy and Heart Disease was initiated by the European Society of Cardiology. Consecutive patients with all forms of cardiovascular disease, presenting with pregnancy, were enrolled with the aim of investigating the pregnancy outcomes. This subgroup of the cohort included 151 women with pulmonary hypertension (PH) either diagnosed by right heart catheterization or diagnosed as possible PH by echocardiographic signs, with 26% having pulmonary arterial hypertension (PAH), in three subgroups: idiopathic (iPAH), associated with congenital heart disease (CHD-PAH), or associated with other disease (oPAH), and 74% having PH caused by left heart disease (LHD-PH, n = 112)...
September 2016: European Journal of Heart Failure
Ebru Ertekin, Iris M van Hagen, Amar M Salam, Titia P E Ruys, Mark R Johnson, Jana Popelova, William A Parsonage, Zeinab Ashour, Avraham Shotan, José M Oliver, Gruschen R Veldtman, Roger Hall, Jolien W Roos-Hesselink
OBJECTIVES: To describe the incidence, onset, predictors and outcome of ventricular tachyarrhythmia (VTA) in pregnant women with heart disease. BACKGROUND: VTA during pregnancy will cause maternal morbidity and even mortality and will have impact on fetal outcome. Insufficient data exist on the incidence and outcome of VTA in pregnancy. METHODS AND RESULTS: From January 2007 up to October 2013, 99 hospitals in 39 countries enrolled 2966 pregnancies in women with structural heart disease...
October 1, 2016: International Journal of Cardiology
Marc-André Koerten, Koichiro Niwa, András Szatmári, Balint Hajnalka, Zoltán Ruzsa, Nicole Nagdyman, Eva Niggemeyer, Brigitte Peters, Karl-Theodor M Schneider, Bettina Kuschel, Yoshiko Mizuno, Felix Berger, Harald Kaemmerer, Ulrike M M Bauer
BACKGROUND: The 2011 guidelines of the European Society of Cardiology (ESC) on the management of cardiovascular diseases during pregnancy define the maternal predictors for neonatal complications. The aim of this study was to determine whether these are associated with an increased number of miscarriages/stillbirths and terminations of pregnancy (TOPs) also in patients with congenital heart defects (CHD). METHODS AND RESULTS: The 634 women from Germany, Hungary and Japan were surveyed concerning the issues of sexuality and reproductive health, as well as their general life situation and medical care...
July 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
Rogelio Castillo-Luna, Osvaldo Miranda-Araujo
BACKGROUND: Pulmonary hypertension is a disease of poor prognosis when is associated with pregnancy. A maternal mortality of 30-56% and a neonatal survival of approximately 85% is reported. Surveillance of patients with severe pulmonary hypertension during pregnancy must be multidisciplinary, to provide information and optimal treatment during and after gestation. Targeted therapy for pulmonary arterial hypertension during pregnancy significantly reduces mortality. The critical period with respect to mortality, is the first month after birth...
December 2015: Ginecología y Obstetricia de México
L Chu, J Zhang, Y N Li, X Meng, Y Y Liu
OBJECTIVE: To investigate the clinical treatment of infective endocarditis with vegetations in pregnant women and the outcomes of the gestation. METHODS: Nine cases of pregnant women diagnosed as infective endocarditis with vegetations in Beijing Anzhen Hospital, Capital Medical University from January 2001 to October 2015 were enrolled in retrospective analysis. Consultations were held by doctors from department of obstetrics, anesthesiology, cardiology, cardial surgery and extracorporeal circulation to decide the individualized treatment plan for the 9 cases of pregnant women after admissions...
May 25, 2016: Zhonghua Fu Chan Ke za Zhi
Qin Fu, Jianhua Lin
OBJECTIVE: To compare the predictive accuracy of three risk assessment systems for cardiac complications among pregnant women with congenital heart disease (CHD). METHODS: In a retrospective study, data were assessed from women with CHD at more than 20weeks of pregnancy who attended Shanghai Obstetrical Cardiology Intensive Care Center, China, between January 1, 1993 and December 31, 2014. CARPREG and ZAHARA risk scores, and modified WHO (mWHO) risk classification were applied retrospectively...
August 2016: International Journal of Gynaecology and Obstetrics
Zijo Begic, Senka Mesihovic Dinarevic, Senad Pesto, Edin Begic, Amra Dobraca, Izet Masic
INTRODUCTION: The most common clinical sign in pediatric cardiology is a heart murmur (organic and inorganic). Organic are sign of heart disease, while inorganic (basically divided into accidental and functional) murmurs occur on anatomically healthy heart. AIM: To determine the justification of the application of the methods of cardiac treatment. PATIENTS AND METHODS: Study included 116 children aged from 1 to 15 years, who were referred due to cardiac treatment to Pediatric Clinic, of Sarajevo University Clinical Center...
April 2016: Acta Informatica Medica: AIM
Marc G Cribbs, David A Briston, Ali N Zaidi
OBJECTIVES: The growing number of women with CHD presents unique challenges, including those related to pregnancy, which can lead to significant morbidity and mortality. We sought to evaluate the perception of paediatric cardiologists towards the reproductive health of women with CHD. METHODS: Paediatric cardiologists in the United States of America were invited to participate in a cross-sectional, anonymous survey. Information solicited included knowledge of contraceptive methods, experience caring for pregnant women with CHD, and referral patterns including the utilisation of high-risk obstetric and adult CHD specialists...
April 11, 2016: Cardiology in the Young
Joanna Koss, Mariola Bidzan, Jerzy Smutek, Leszek Bidzan
BACKGROUND: The aim of this study was to analyze the influence of the level of perinatal depression on the labor-associated fear and emotional attachment of children born to women during high-risk pregnancies and in the first days after delivery. MATERIAL/METHODS: 133 women aged between 16 and 45 years took part in the study. The first group included 63 pregnant women (mean age=28.59, SD=5.578) with a high-risk pregnancy (of maternal origin, for example, cardiologic disorders and diabetes)...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Iris M van Hagen, Eric Boersma, Mark R Johnson, Sara A Thorne, William A Parsonage, Pilar Escribano Subías, Agata Leśniak-Sobelga, Olga Irtyuga, Khaled A Sorour, Nasser Taha, Aldo P Maggioni, Roger Hall, Jolien W Roos-Hesselink
AIMS: To validate the modified World Health Organization (mWHO) risk classification in advanced and emerging countries, and to identify additional risk factors for cardiac events during pregnancy. METHODS AND RESULTS: The ongoing prospective worldwide Registry Of Pregnancy And Cardiac disease (ROPAC) included 2742 pregnant women (mean age ± standard deviation, 29.2 ± 5.5 years) with established cardiac disease: 1827 from advanced countries and 915 from emerging countries...
May 2016: European Journal of Heart Failure
Malavika Prabhu, Allison Bryant
The incidence of congenital cardiac disease among reproductive-aged women is increasing. Understanding the unique physiology of pregnancy and the postpartum period is critical to helping women achieve successful pregnancy outcomes. Risk assessment models estimate the cardiac, obstetric, and neonatal risks a woman may face and influence the conversations regarding pregnancy and contraception management. This review focuses on some of the most common congenital cardiac lesion encountered during pregnancy, as well as key aspects of antepartum, intrapartum, and postpartum care for these women...
May 2016: Current Treatment Options in Cardiovascular Medicine
Marcelo Rodríguez, Jose Moreno, Rolando Márquez, Ricardo Eltit, Felipe Martinez, Alvaro Sepúlveda-Martínez, Mauro Parra-Cordero
OBJECTIVE: To evaluate the fetal mechanical PR interval in fetuses from pregnancies with intrahepatic cholestasis of pregnancy (ICP). METHODS: A case-control study was conducted in the Maternal-Fetal Medicine Unit at Hospital Carlos Van Buren between 2011 and 2013. Fetal echocardiography was performed in patients with ICP and normal pregnancies. Demographic and clinical characteristics were compared using the Mann-Whitney U test for continuous variables. A p value <0...
March 10, 2016: Fetal Diagnosis and Therapy
Matthew P Romagano, Joanne N Quiñones, Amy Ahnert, Rafael Martinez, John C Smulian
BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia is a genetic disorder in which ventricular tachycardia occurs in the absence of structural heart disease or a prolonged QT interval. If untreated, there is a high incidence of sudden cardiac death. Management of this cardiac condition during pregnancy merits a multidisciplinary approach. CASE: A nulliparous woman with catecholaminergic polymorphic ventricular tachycardia presented at 15 weeks of gestation...
April 2016: Obstetrics and Gynecology
Leonid Barbarash, Natalya Rutkovskaya, Olga Barbarash, Yuri Odarenko, Alexander Stasev, Evgenya Uchasova
BACKGROUND: The problem of prosthetic heart valve selection in fertile women with acquired heart defects remains crucial in modern cardiology. Mechanical heart valves require lifelong indirect anticoagulant therapy, which has significant fetal toxicity and is unacceptable for women planning pregnancy. Bioprosthetic heart valves are the best choice for fertile women; however, their durability is limited, and reoperations are required. CASE PRESENTATION: We describe the clinical case of a 21-year-old Russian woman with infectious endocarditis who underwent heart valve replacement with an epoxy-treated mitral valve prosthesis...
2016: Journal of Medical Case Reports
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