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Solitary Fibrous Tumor

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https://www.readbyqxmd.com/read/28644098/intracranial-solitary-fibrous-tumors-hemangiopericytomas-first-report-of-malignant-progression
#1
Caroline Apra, Karima Mokhtari, Philippe Cornu, Matthieu Peyre, Michel Kalamarides
OBJECTIVE Meningeal solitary fibrous tumors/hemangiopericytomas (MSFTs/HPCs) are rare intracranial tumors resembling meningiomas. Their classification was redefined in 2016 by the World Health Organization (WHO) as benign Grade I fibrohyaline type, intermediate Grade II hypercellular type, and malignant highly mitotic Grade III. This grouping is based on common histological features and identification of a common NAB2-STAT6 fusion. METHODS The authors retrospectively identified 49 cases of MSFT/HPC. Clinical data were obtained from the medical records, and all cases were analyzed according to this new 2016 WHO grading classification in order to identify malignant transformations...
June 23, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28621469/solitary-fibrous-tumor-of-the-breast-a-case-report-and-the-review-of-the-literature
#2
Nikolaos S Salemis
Solitary fibrous tumors (SFT) are rare mesenchymal neoplasms. They were first described as spindle-cell tumors originating from the pleura, but they may arise in any anatomical site. SFT of the breast is an exceedingly rare clinical entity. Our literature review yielded only 21 cases reported so far. We describe a case of a SFT of the breast in a premenopausal patient who presented with a gradually enlarging palpable breast mass. Diagnostic evaluation and management are discussed along with a review of the relevant literature...
June 16, 2017: Breast Journal
https://www.readbyqxmd.com/read/28620640/solitary-fibrous-tumor-of-retromolar-pad-a-rare-challenging-case
#3
Ali Lotfi, Sepideh Mokhtari, Mohammad Moshref, Maryam Shahla, Saede Atarbashi Moghadam
Solitary fibrous tumor has a wide spectrum of histopathologic features and many tumors show similar microscopic features. This similarity poses diagnostic challenges to the pathologists and immunohistochemical analysis is required in many cases. Moreover, it is a rare entity in orofacial region which consequently would make its diagnosis more challenging in oral cavity. The knowledge of various microscopic patterns of this tumor contributes to a proper diagnosis and prevents unnecessary treatment. This study reports a case of solitary fibrous tumor in the retromolar pad area and discusses its various histological features and differential diagnoses...
June 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28614212/phosphaturic-mesenchymal-tumors-clinicopathologic-immunohistochemical-and-molecular-analysis-of-22-cases-expanding-their-morphologic-and-immunophenotypic-spectrum
#4
Abbas Agaimy, Michael Michal, Simion Chiosea, Fredrik Petersson, Ladislav Hadravsky, Glenn Kristiansen, Raymund E Horch, Jan Schmolders, Arndt Hartmann, Florian Haller, Michal Michal
Phosphaturic mesenchymal tumor (PMT) is a rare neoplasm of uncertain histogenesis that has been linked to tumor-induced osteomalacia (TIO) since 1959. The neoplastic cells produce increased amount of FGF23 which results in TIO via uncontrolled renal loss of phosphate (phosphaturia), and consequently diminished bone mineralization. To date, ∼300 cases have been reported. Although there is increasing evidence that PMT can be diagnosed by reproducible histopathologic features, firm diagnosis has been often restricted to cases associated with TIO and, hence, diagnosis of "nonphosphaturic variants" remained challenging...
June 13, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28595233/-solitary-fibrous-tumor-originating-from-the-visceral-pleura-presenting-an-extrapleural-sign-report-of-a-case
#5
Kyosuke Matsunaga, Yusuke Takanashi, Shogo Tajima, Takamitsu Hayakawa, Hiroshi Neyatani
We report a case of solitary fibrous tumor (SFT) originating from the visceral pleura, which presented an extrapleural sign on chest computed tomography (CT) and magnetic resonance imaging (MRI). A 44-year-old woman presented at our hospital for a growing mass visible in chest X-rays. Chest CT and MRI detected a 27×12 mm lesion on the intrathoracic side of the right 3rd intercostal space. The extrapleural signs strongly suggested the tumor to be chest wall origin. However, the tumor was found to be pedunculate with an umbrella-like appearance locating on the visceral pleura of the lung...
June 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28555487/is-stereotactic-radiosurgery-a-treatment-option-for-intracranial-solitary-fibrous-tumors
#6
Edson Oliveira, Frederico Guerreiro, José P Lavrador, José Pimentel, António Gonçalves-Ferreira, Herculano Carvalho, João P Farias
No abstract text is available yet for this article.
August 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28552537/comparison-and-evaluation-of-risk-factors-for-meningeal-pleural-and-extrapleural-solitary-fibrous-tumors-a-clinicopathological-study-of-92-cases-confirmed-by-stat6-immunohistochemical-staining
#7
Ji Min Kim, Yoon-La Choi, Yu Jin Kim, Hyung Kyu Park
Solitary fibrous tumors (SFTs) are an uncommon type of mesenchymal tumors that are presumably fibroblastic in nature. SFTs are translocation-associated neoplasms that can be consistently diagnosed through the evaluation of NAB2/STAT6 gene fusion. Currently, SFTs have a different grading system and criteria according to their primary sites, and the differences and similarities in SFTs according to their primary sites are still poorly understood. Therefore, we compared SFTs according to their primary sites and histologic appearance, and validated the current grading system of SFTs...
June 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28551649/rare-neoplasm-mimicking-neuoroendocrine-pancreatic-tumor-a-case-report-of-solitary-fibrous-tumor-with-review-of-the-literature
#8
Francesco E D'Amico, Cesare Ruffolo, Maurizio Romano, Marina DI Domenico, Marta Sbaraglia, Angelo P Dei Tos, Tiziana Garofalo, Antonio Giordano, Iccolò Bassi, Marco Massani
BACKGROUND: Solitary fibrous tumors (SFTs) are rare biological entities described mainly in the pleura. To date, in the pancreas, only 14 cases have been reported in the English literature. CASE REPORT: A 52-year-old male was diagnosed incidentally with a suspected neuroendocrine tumor (NET) of the pancreas. He underwent pancreatic enucleation of the mass, which, at final pathology, showed spindle cell proliferation set in a collagenous background and featuring the presence of hemangiopericytoma-like blood...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28550821/solitary-fibrous-tumors-of-the-pleura-current-diagnostic-tools
#9
Robert R J Coebergh van den Braak, Klaas A Hartholt, Ben J Pannekoek, Frank Smedts, Maarten van der Elst
No abstract text is available yet for this article.
March 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28549594/-recommendations-for-the-organ-donation-from-patients-with-brain-or-medullary-primitive-tumors-on-behalf-of-the-association-of-the-neuro-oncologists-of-french-expression-anocef-and-the-club-of-neuro-oncology-of-the-french-society-of-neurosurgery
#10
Didier Frappaz, Emilie Le Rhun, Arnaud Dagain, Benoît Averland, Luc Bauchet, Alexandre Faure, Christian Guillaume, Sonia Zouaoui, François Provot, Florence Vachiery, Luc Taillandier, Khê Hoang-Xuan
Requests of organs to be transplanted increase. As a matter of urgency, it is not always easy to decide if a patient carrier of a brain tumor can be candidate in the donation. After a review of the literature, the members of the Association of the Neuro-oncologists of French Expression (ANOCEF) and the Club of Neuro-oncology of the French Society of Neurosurgery propose consensual recommendations in case of donor carrier of primitive tumor intra-cranial or intra-medullary. A contact with the neuro-oncologist/neurosurgeon will allow to discuss the indication in case of glioma of grade I/II/III, according to the grade, the current status (absence of progressive disease), the number of surgeries and of lines of treatment...
May 23, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28538410/extrapleural-solitary-fibrous-tumor-in-thymic-area-a-case-report
#11
Eun Kyung Jung, Young Yoon Kim, Dong Hoon Lee, Kyung Hwa Lee, Joon Kyoo Lee
RATIONALE: Solitary fibrous tumor (SFT) is a rare benign soft tissue mesenchymal neoplasm. There have been a few reports of extrapleural SFTs although it can occur anywhere in the body. PATIENT CONCERNS: A 30-year-old male presented with an anterior neck mass since one month. DIAGNOSES: Based on physical and radiologic examination, preliminary differential diagnosis was thymic neoplasm or intrathoracic goiter. INTERVENTIONS: We performed surgical excision of the neck mass...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28533644/atypical-parathyroid-adenoma-with-multiple-brown-tumors-as-initial-presentation-a-rare-entity
#12
V S Krishna Mohan, Manishi L Narayan, Arun Mukka, Bharath Bachimanchi, Amit Kumar Chowhan, B Vijayalakshmi Devi, Suresh Vaikkakara, Alok Sachan
Brown tumors seen in hyperparathyroidism are rare, non-neoplastic lesions because of abnormal bone metabolism, and they can mimic benign bone tumors or malignancy. Although biopsy is considered as the gold standard for diagnosis, it can be inconclusive. As the diagnosis of brown tumors is often challenging, a high index of suspicion is essential for diagnosis. We present a case of 21-year-old woman who presented with multiple painful bony lesions, which were initially misdiagnosed as fibrous dysplasia. Due to persistent bone pain and deterioration in her physical mobility, she was referred to tertiary care centre...
April 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28528063/an-involuntary-and-unexpected-treatment-of-nutcracker-esophagus
#13
Diane Mege, Alban Benezech, Henri de Lesquen, Véronique Vitton, Pascal-Alexandre Thomas
A 76-year-old woman complained of painful dysphagia and loss of weight. Esophagoscopy results were negative, whereas computed tomography (CT) disclosed a 25-mm mediastinal tumor without a connection to the esophagus. A diagnosis of nutcracker esophagus was made on high-resolution esophageal manometry. Peroral endoscopic esophageal myotomy failed to improve the symptoms. Right video thoracoscopy allowed resection of the tumor, which looked like a neurogenic tumor of the posterior mediastinum that developed from the right vagus nerve...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28515414/mediastinal-solitary-fibrous-tumor-diagnosed-by-endobronchial-ultrasound-directed-biopsy
#14
Alaina J Webb, Ahmed S Yassin, Ali Saeed, Hemang Yadav, James P Utz
BACKGROUND Solitary fibrous tumors of the middle mediastinal space are uncommon and often not discovered until symptoms secondary to compression of adjacent structures occur. Diagnosis requires surgical biopsy and histological tissue analysis. We describe the ECHO appearance of the solitary fibrous tumor and successful non-invasive EBUS diagnosis. This method of diagnosis allowed for surgical planning for resection and allowed us to exclude non-surgical diseases, such as small cell carcinoma. CASE REPORT A 32-year-old man presented to his primary care physician with worsening intermittent chronic chest pain with recent progressive dysphagia, cough, and dyspnea...
May 18, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28512044/spinal-solitary-fibrous-tumor-hemangiopericytoma-a-clinicopathological-and-radiological-analysis-of-eleven-cases
#15
Xiaoping Yi, Desheng Xiao, Yujiao He, Hongling Yin, Guanghui Gong, Xueying Long, Weihua Liao, Xuejun Li, Lunquan Sun, Youming Zhang, Bo Zhang
PURPOSE: To retrospectively review the clinicopathological features and computed tomography (CT) and magnetic resonance imaging (MRI) findings of spinal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) tumors. MATERIALS AND METHODS: Eleven patients with surgically and pathologically confirmed spinal SFT/HPC were enrolled. Their clinicopathological data and imaging findings were retrospectively reviewed. RESULTS: There were eight male and three female patients with a median age of 42 years (range, 26-65 years)...
May 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28493803/soft-tissue-sarcomas-of-the-abdomen-and-pelvis-radiologic-pathologic-features-part-2-uncommon-sarcomas
#16
Angela D Levy, Maria A Manning, Markku M Miettinen
Soft-tissue sarcomas occurring in the abdomen and pelvis are an uncommon but important group of malignancies. Recent changes to the World Health Organization classification of soft-tissue tumors include the movement of gastrointestinal stromal tumors (GISTs) into the soft-tissue tumor classification. GIST is the most common intraperitoneal sarcoma. Liposarcoma is the most common retroperitoneal sarcoma, and leiomyosarcoma is the second most common. GIST, liposarcoma, and leiomyosarcoma account for the majority of sarcomas encountered in the abdomen and pelvis and are discussed in part 1 of this article...
May 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28490698/-diagnosis-and-differential-diagnosis-for-solitary-fibrous-tumor-in-the-abdomen-and-pelvis-by-ct
#17
Huaping Liu, Wenzheng Li, Xiaoping Yi, Yigang Pei, Hui Liu, Wei Zhao, Wenguang Liu, Jiale Hou, Obin Ghimire
To study the CT features for solitary fibrous tumor (SFT) in the abdomen and pelvis and to improve the diagnostic accuracy.
 Methods: Fourteen patients with SFT were collected in our hospital from January, 2011 to December, 2015. Characteristic of images were analyzed and compared for 10 SFT, which located outside the abdominal organs with extragastrointestinal stromal tumors (EGIST), leiomyosarcoma, and schwannoma.
 Results: Necrosis and cystic formation were frequently present in SFT in the abdomen and pelvis...
April 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28487319/rare-solitary-fibrous-tumor-in-the-pulmonary-artery-mimicking-pulmonary-embolism
#18
Rui Luo, Hui Xu, Pingyang Zhang, Fei Ye, Feng Wang
No abstract text is available yet for this article.
May 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28484679/rare-solitary-fibrous-tumor-in-the-pediatric-neck-a-case-report-and-review-of-the-literature
#19
G Zachary White, Eric L Cox, Erich J Schwartz, Shant A Korkigian
Solitary fibrous tumors (SFT) are a rare type of mesenchymal-derived tumor not commonly found in the pediatric population, especially in the head and neck. Tumors of this nature are most commonly seen in the adult population and are identified with unique immunohistochemical markers, specifically signal transducer and activator of transcription 6 (STAT6) and hematopoietic progenitor cell antigen (CD34). Including SFTs in the differential diagnosis while working up a mass can be difficult considering their relatively non-descript appearance on imaging and the low yield immunohistochemical staining that must be ordered to confirm diagnosis...
April 6, 2017: Curēus
https://www.readbyqxmd.com/read/28469319/fine-needle-aspiration-cytology-of-solitary-fibrous-tumor-of-the-orbit
#20
Vani Krishnamurthy, S Suchitha, M Asha, G V Manjunath
Solitary fibrous tumor (SFT) is a distinct and a rare spindle cell neoplasm, commonly known to occur in the pleura and other serosal sites. With the advent of immunohistochemistry, varied extraserosal sites are being recognized as common locations for this rare tumor. We report a case of SFT in a 50-year-old male patient who presented with multiple swellings in the eyelid, with emphasis on the cytological features.
April 2017: Journal of Cytology
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