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Solitary Fibrous Tumor

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https://www.readbyqxmd.com/read/29204027/a-simplified-overview-of-world-health-organization-classification-update-of-central-nervous-system-tumors-2016
#1
REVIEW
Anshu Gupta, Tanima Dwivedi
After 8 years, an update of central nervous system (CNS) tumors was published in 2016 after 2007. First time ever, molecular markers along with histology have been used in classification of any tumor. Major changes are seen in glioma and medulloblastoma groups. Few entities have been added such as diffuse midline glioma, H3 K27M-mutant, RELA fusion-positive ependymoma, embryonal tumor with multilayered rosettes, C19MC-altered, and hybrid nerve sheath tumors. Few variants and patterns that no longer have diagnostic and/or biological relevance and have been deleted such as glioblastoma cerebri, protoplasmic and fibrillary astrocytoma, and cellular ependymoma...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29201988/solitary-fibrous-tumor-of-the-vulva-resulting-in-spinal-metastasis-a-case-report
#2
Diana C Pearre, Jerome J Federspiel, Francis C Grumbine
•Solitary fibrous tumors are typically indolent tumors of the pleura.•Primary origin in the female reproductive organs is rare, as are aggressive forms.•We report a case of a vulvar solitary fibrous tumor, notable for extensive spinal metastasis.
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29200960/solitary-fibrous-tumor-occurring-in-the-parotid-gland-a-case-report
#3
Meryem Rais, Amine Kessab, Zahra Sayad, Sanae El Mourabit, Redallah Zrarqi, Salma Benazzou, Malik Boulaadas, Nadia Cherradi
Background: Solitary fibrous tumor is an uncommon spindle cell neoplasm of unknown origin. It has been reported in many anatomic sites, with a rare occurrence in the head and neck region. Solitary fibrous tumors of the parotid gland are exceptional; their clinical and radiologic features are non specific, often mimicking more common salivary gland tumors. Pathologic examination and immunohistochemistry are required to make the correct diagnosis. The prognosis is favorable, with most tumors being benign, and complete surgical resection is the treatment of choice...
2017: BMC Clinical Pathology
https://www.readbyqxmd.com/read/29168109/a-case-of-glomangiopericytoma-at-the-nasal-septum
#4
Takashi Anzai, Tsuyoshi Saito, Sho Tsuyama, Miri Toh, Katsuhisa Ikeda, Shin Ito
Glomangiopericytoma (GPC) is a rare sinonasal perivascular tumor that accounts for < 0.5-1% of all sinonasal tumors. GPC is categorized as a low-grade neoplasm with borderline malignancy and a tendency of local recurrence. GPC is a rare mesenchymal neoplasm characterized by the perivascular proliferation of tumor cells, and it requires being distinguished from solitary fibrous tumors. Here, we report a case of GPC in a 68-year-old male patient who presented at the emergency room of our hospital with a complaint of sudden epistaxis...
November 22, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/29159525/hepatic-tumors-of-vascular-origin-imaging-appearances
#5
Eric C Ehman, Michael S Torbenson, Michael L Wells, Brian T Welch, Scott M Thompson, Ishan Garg, Sudhakar K Venkatesh
A number of benign and malignant neoplasms may arise from the vascular elements within the liver parenchyma. Lesions discussed in this article include angiosarcoma, epithelioid hemangioendothelioma, solitary fibrous tumor (hemangiopericytoma), infantile, and cavernous hemangiomas. Despite a common theme of vascular origin, the pathologic and imaging appearance of these entities can be heterogeneous. Angiosarcomas are bizarrely enhancing, highly aggressive tumors, which often present with metastatic disease...
November 20, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29159031/solitary-fibrous-tumor-of-the-abdominal-wall-re-surfacing-as-unilateral-pleural-effusion-and-mass-a-case-report-and-review-of-the-literature
#6
Xia Bi, Jixian Zhai, Carrie D Chun
Background: Solitary fibrous tumors (SFTs) are rare fibroblastic mesenchymal neoplasms that were initially described in the pleura, but have been increasingly recognized to occur in other parts of the body. They have been traditionally regarded as indolent tumors that are rare to metastasize after surgical resection. Here, we describe a case of a Filipino female who initially presented with unilateral pleural effusion and mass, and was ultimately diagnosed with recurrent solitary fibrous tumor that originated from the abdominal wall...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29138700/retroperitoneal-solitary-fibrous-tumor-a-patternless-tumor
#7
D Myoteri, D Dellaportas, C Nastos, I Gioti, G Gkiokas, E Carvounis, T Theodosopoulos
Introduction: Solitary fibrous tumor is a rare type of mesenchymal, spindle-cell tumor reported mostly in the pleura. Retroperitoneal occurrence is rare and histopathological diagnosis is challenging. Case Presentation: A 55-year-old woman with nonspecific abdominal pain was found to have a retroperitoneal/pelvic mass adjacent to the upper rectum. The patient underwent surgical resection in clear margins of this pelvic tumor, entering the total mesenteric excision surgical plane...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/29131777/malignant-solitary-fibrous-tumor-of-the-liver-airp-best-cases-in-radiologic-pathologic-correlation
#8
Cátia Esteves, Tiago Maia, José Manuel Lopes, Madalena Pimenta
Editor's Note.-RadioGraphics continues to publish radiologic-pathologic case material selected from the American Institute for Radiologic Pathology (AIRP) "best case" presentations. The AIRP conducts a 4-week Radiologic Pathology Correlation Course, which is offered five times per year. On the penultimate day of the course, the best case presentation is held at the American Film Institute Silver Theater and Cultural Center in Silver Spring, Md. The AIRP faculty identifies the best cases, from each organ system, brought by the resident attendees...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29127695/management-of-the-other-retroperitoneal-sarcomas
#9
REVIEW
Piotr L Rutkowski, John T Mullen
The focus of this review is on the management of the less common sarcomas occurring in the retroperitoneal space, including solitary fibrous tumor (SFT), malignant peripheral nerve sheath tumor (MPNST), perivascular epithelioid cell tumor (PEComa), and undifferentiated pleomorphic sarcoma (UPS) of the psoas muscle. As for other retroperitoneal sarcomas, surgical resection is the mainstay of curative therapy, and multidisciplinary preoperative assessment, including percutaneous needle biopsy for histologic confirmation, is the basis for personalized management, as the surgical management, and the integration of systemic therapy and radiation therapy is unique to each histologic subtype...
November 11, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29127512/surgical-management-of-spinal-solitary-fibrous-tumor-hemangiopericytoma-a-case-series-of-20-patients
#10
Qi Jia, Zhenhua Zhou, Dan Zhang, Jian Yang, Chao Liu, Ting Wang, Zhipeng Wu, Cheng Yang, Haifeng Wei, Jian Zhao, Tielong Liu, Wang Zhou, Xinghai Yang, Jianru Xiao
PURPOSE: Spinal solitary fibrous tumor/hemangiopericytoma (SFT/HPC), a rare mesenchymal tumor that arises from pericytes of Zimmerman, comprises only 0.08% of all primary bone tumors and 0.1% of primary malignant bone tumor and rarely occurs in the spine. We attempt to correlate the clinical factors and different treatment options with the recurrence rate and overall survival of SFT/HPC over time. METHODS: A retrospective study of 20 patients with spinal osseous SFT/HPCs who were surgically treated in our center between 2003 and 2015 was performed...
November 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29120140/genetic-aberration-in-solitary-fibrous-tumors-and-its-clinical-relevance
#11
Jie Chen, Aimee Crago, Biqiang Zheng, Chunmeng Wang, Yingqiang Shi, Yong Chen
No abstract text is available yet for this article.
December 2017: Minerva Medica
https://www.readbyqxmd.com/read/29106748/solitary-fibrous-tumor-of-the-female-genital-tract-a-clinicopathologic-analysis-of-25-cases
#12
Eric J Yang, Brooke E Howitt, Christopher Dm Fletcher, Marisa R Nucci
AIMS: Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm of fibroblastic origin, first described as a tumor of the pleura and now well established at extrapleural sites. However, SFT in the female genital tract is rare and therefore not fully characterized. MATERIAL AND RESULTS: We describe a series of 25 SFTs arising throughout the gynecologic tract, including vulva (14 cases), vagina (1), cervix (1), uterus (6), ovary (2) and fallopian tube (1)...
November 6, 2017: Histopathology
https://www.readbyqxmd.com/read/29100675/skull-base-plasmacytoma-a-unique-case-of-poems-syndrome-with-a-plasmacytoma-causing-craniocervical-instability
#13
Hannah Gilder, Meghan E Murphy, Mohammed Ali Alvi, Panagiotis Kerezoudis, Daniel Shepherd, Patrick R Maloney, Michael J Yaszemski, Jonathan M Morris, Angela Dispenzieri, Jane M Matsumoto, Mohamad Bydon
INTRODUCTION: Plasmacytomas, considered to be the solitary counterparts of multiple myeloma, are neoplastic monoclonal plasma cell proliferations within soft tissue or bone. Plasmacytomas often present as a collection of findings known as POEMS-syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein spike, and Skin changes). CASE DESCRIPTION: We present a report of a 47 yo male diagnosed with POEMS-syndrome secondary to a skull base plasmacytoma. The mass resulted in marked instability of the cranio-cervical junction due to bony erosion...
October 31, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29090207/solitary-fibrous-tumor-in-buccal-cheek-mucosa
#14
Chung-Min Yoon, Jeong-Min Cho, Kwang-Ryeol Lim, Seok-Kwun Kim, Su-Jin Kim, Keun-Cheol Lee
A solitary fibrous tumor is a relatively uncommon neoplasm that usually occurs in the pleura but occurs extremely rarely in the oral cavity. Reported herein is a rare case of a solitary fibrous tumor in the buccal cheek mucosa. A 50-year-old man visited the authors' hospital due to a buccal cheek mass whose size had increased. Excisional biopsy was done under local anesthesia. After the excisional biopsy, the patient was diagnosed to have a solitary fibrous tumor. In immunohistochemistry, the patient's solitary fibrous tumor was characterized by the expression of CD34 and CD99 on the neoplastic cells, and negativity for Bcl-2 and S-100...
September 2017: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29075420/solitary-fibrous-tumor-of-the-floor-of-the-mouth
#15
Renata-Miranda Rodrigues, Aethel-Gladys de Oliveira Fernandes, Silvia-Paula de Oliveira, Danielle-Resende Camisasca, André-Aguiar Marques, Simone-de Queiroz Chaves Lourenço
BACKGROUND: A solitary fibrous tumor (SFT) of the oral cavity is an extremely rare entity. Its diagnosis is complicated because of its diverse morphology and similarity to other mesenchymal diseases. CASE REPORT: A rare case of SFT involving floor of the mouth is presented. The tumor was well circumscribed and almost spherical, measuring approximately 3 cm in diameter. Patient was submitted to biopsy and histopathologic examination showed a tumor composed of spindle to epithelioid cells showing pale to eosinophilic cytoplasm, oval or elongated nuclei with inconspicuous nucleoli...
September 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29050079/-pineal-malignant-solitary-fibrous-tumor-report-of-two-cases
#16
H J Huang, Y H Yu, Z Y Zheng
No abstract text is available yet for this article.
October 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29039030/size-and-location-are-the-most-important-risk-factors-for-malignant-behavior-in-resected-solitary-fibrous-tumors
#17
Sepideh Gholami, Michael R Cassidy, Amanda Kirane, Deborah Kuk, Bhumika Zanchelli, Christina R Antonescu, Samuel Singer, Murray Brennan
PURPOSE: While previously thought to be clinically indolent, recent data suggest significant late metastatic capacity of solitary fibrous tumors (SFTs). We define prognostic factors for recurrence and disease-specific death (DSD) in resected primary SFTs. METHODS: Resected primary SFTs from 1982 to 2015 were identified from a prospective, single institutional database. Risk factors for local (LR) and distant recurrence (DR), and DSD were assessed using competing risk analysis...
December 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29028514/solitary-fibrous-tumor-in-the-abdomen-and-pelvis-a-case-series-with-radiological-findings-and-treatment-recommendations
#18
Adrian Fernandez, Miles Conrad, Ryan M Gill, Won-Tak Choi, Vishal Kumar, Spencer Behr
This study presents the radiological findings of seven cases of solitary fibrous tumor (SFT) in the abdomen and pelvis. A retrospective search of the pathology database at our institution was performed to identify cases of SFT in the abdomen and pelvis. After identifying seven cases, cross-sectional imaging was reviewed and characterized. We conclude that SFTs in the abdomen and pelvis should be considered with well-defined, circular, hypervascular masses. Pelvic SFTs should be considered with homogenous, avidly enhancing masses...
October 7, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29016372/the-peculiar-case-of-a-large-right-lower-quadrant-solitary-fibrous-tumor-with-vasculature-arising-from-the-splenic-artery-and-vein
#19
Andrew Jeremy Lukaszewicz, Harold Hayes, Mary Maunglay, Raman Muhar, Grygori Gerasymchuk, Shameem Menon
We present the interesting case of a patient with peritoneal solitary fibrous tumor (SFT). The patient initially presented with right lower quadrant pain. Computed tomography findings revealed the presence of a large mass near the cecum, with both arterial and venous blood supply arising directly from the splenic artery and vein. The patient ultimately underwent surgical excision of the mass, and pathological examination was consistent with benign SFT. Not only is the location of our patient's tumor exceedingly rare, but also, to our knowledge, it is the first reported case of SFT with such a unique vascular supply...
November 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28976138/leiomyosarcoma-of-maxilla-a-case-report-with-review-of-literature
#20
Renuka Gupta, Madhusudan Astekar, Ramakant Dandriyal, Manjunath Bs
One challenging feature of head and neck pathology is that a dizzying array of spindle cell lesions occurs here which ranges all the way from reactive, very aggressive forms to malignant lesions. Leiomyosarcoma is one such malignant tumour of mesenchymal origin exhibiting smooth muscle differentiation; presenting generally nonspecific signs and symptoms. Here we present a case of leiomyosarcoma in a 21 year old female patient associated with single reddish pink swelling present in the posterior right maxillary tuberosity region with moderate facial asymmetry...
September 2017: Journal of Experimental Therapeutics & Oncology
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