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https://www.readbyqxmd.com/read/28922900/grass-pollen-affects-survival-and-development-of-larval-anopheles-arabiensis-diptera-culicidae
#1
Yelfwagash Asmare, Richard J Hopkins, Habte Tekie, Sharon R Hill, Rickard Ignell
Nutrients in breeding sites are critical for the survival and development of malaria mosquitoes, having a direct impact on vectorial capacity. Yet, there is a limited understanding about the natural larval diet and its impact on the individual fitness of mosquitoes. Recent studies have shown that gravid Anopheles arabiensis Patton (Diptera: Culicidae) are attracted by and oviposit in grass-associated habitats. The pollen provided by these grasses is a potential source of nutrients for the larvae. Here, we assess the effect of Typha latifolia L...
September 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28922869/genome-organization-of-sphingobium-indicum-b90a-an-archetypal-hexachlorocyclohexane-hch-degrading-genotype
#2
Helianthous Verma, Abhay Bajaj, Roshan Kumar, Jasvinder Kaur, Shailly Anand, Namita Nayyar, Akshita Puri, Yogendra Singh, Jitendra P Khurana, Rup Lal
Among sphingomonads, Sphingobium indicum B90A is widely investigated for its ability to degrade a manmade pesticide, γ-hexachlorocyclohexane (γ-HCH) and its isomers (α-, β-, δ-, and ε-HCH). In this study, complete genome of strain B90A was constructed using Single Molecule Real Time Sequencing (SMRT) and Illumina platform. The complete genome revealed that strain B90A harbors four replicons: one chromosome (3,654,322 bp) and three plasmids designated as pSRL1 (139,218 bp), pSRL2 (108,430 bp) and pSRL3 (43,761 bp)...
September 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28922664/patchy-particles-made-by-colloidal-fusion
#3
Zhe Gong, Theodore Hueckel, Gi-Ra Yi, Stefano Sacanna
Patches on the surfaces of colloidal particles provide directional information that enables the self-assembly of the particles into higher-order structures. Although computational tools can make quantitative predictions and can generate design rules that link the patch motif of a particle to its internal microstructure and to the emergent properties of the self-assembled materials, the experimental realization of model systems of particles with surface patches (or 'patchy' particles) remains a challenge. Synthetic patchy colloidal particles are often poor geometric approximations of the digital building blocks used in simulations and can only rarely be manufactured in sufficiently high yields to be routinely used as experimental model systems...
September 18, 2017: Nature
https://www.readbyqxmd.com/read/28922652/a-pilot-study-of-loss-aversion-for-drug-and-non-drug-commodities-in-cocaine-users
#4
Justin C Strickland, Joshua S Beckmann, Craig R Rush, William W Stoops
BACKGROUND: Numerous studies in behavioral economics have demonstrated that individuals are more sensitive to the prospect of a loss than a gain (i.e., loss aversion). Although loss aversion has been well described in "healthy" populations, little research exists in individuals with substance use disorders. This gap is notable considering the prominent role that choice and decision-making play in drug use. The purpose of this pilot study was to evaluate loss aversion in active cocaine users...
September 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28922638/reverse-flow-injection-spectrophotometric-determination-of-ciprofloxacin-in-pharmaceuticals-using-iron-from-soil-as-a-green-reagent
#5
Sysay Palamy, Wirat Ruengsitagoon
A novel reverse flow injection spectrophotometric method for the determination of ciprofloxacin was successfully combined with the on-line introduction of an iron solution extracted from soil as green reagent. The assay was optimized by a univariate method to select the optimum conditions for the highest absorbance and highest stability of the complex. Beer-Lambert's law (λmax=440nm) is obeyed in the range 0.5-50μgmL(-1) with a correlation coefficient (r(2)) of 0.9976 and 0.9996 using soil as green reagent from Khon Kaen, Thailand and Vientiane, Laos, respectively...
September 13, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28922552/an-individualized-gene-expression-signature-for-prediction-of-lung-adenocarcinoma-metastases
#6
Lishuang Qi, Tianhao Li, Gengen Shi, Jiasheng Wang, Xin Li, Sainan Zhang, Libin Chen, Yuan Qin, Yunyan Gu, Wenyuan Zhao, Zheng Guo
Our laboratory previously reported an individual-level signature consisting of nine gene pairs, named 9-GPS. This signature was developed by training on microarray expression data and validated using three independent integrated microarray data sets, with samples of stage I non-small cell lung cancer after complete surgical resection. In this study, we first validated the cross-platform robustness of 9-GPS by demonstrating that 9-GPS could significantly stratify the overall survival of 213 stage I lung adenocarcinoma (LUAD) patients detected with RNA-sequencing platform in The Cancer Genome Atlas (log-rank p = 0...
September 18, 2017: Molecular Oncology
https://www.readbyqxmd.com/read/28922515/increased-resource-use-efficiency-amplifies-positive-response-of-aquatic-primary-production-to-experimental-warming
#7
James M Hood, Jonathan P Benstead, Wyatt F Cross, Alexander D Huryn, Philip W Johnson, Gísli M Gíslason, James R Junker, Daniel Nelson, Jón S Ólafsson, Chau Tran
Climate warming is affecting the structure and function of river ecosystems, including their role in transforming and transporting carbon (C), nitrogen (N), and phosphorus (P). Predicting how river ecosystems respond to warming has been hindered by a dearth of information about how otherwise well-studied physiological responses to temperature scale from organismal to ecosystem levels. We conducted an ecosystem-level temperature manipulation to quantify how coupling of stream ecosystem metabolism and nutrient uptake responded to a realistic warming scenario...
September 18, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28922364/association-of-epicardial-adipose-tissue-with-serum-level-of-cystatin-c-in-type-2-diabetes
#8
Tomomi Murai, Noriko Takebe, Kan Nagasawa, Yusuke Todate, Riyuki Nakagawa, Rieko Nakano, Mari Hangai, Yutaka Hasegawa, Yoshihiko Takahashi, Kunihiro Yoshioka, Yasushi Ishigaki
OBJECTIVE: Accumulation of epicardial adipose tissue (EAT) is considered to be a cardiovascular risk factor independent from visceral adiposity, obesity, hypertension and diabetes. We explored the parameters related to EAT accumulation, aiming to clarify the novel pathophysiological roles of EAT in subjects with type 2 diabetes (T2DM). METHODS: We examined the laboratory values, including cystatinC, and surrogate markers used for evaluating atherosclerosis. EAT was measured as the sum of the adipose tissue area, obtained by plain computed tomography scans in 208 subjects with T2DM but no history of coronary artery disease...
2017: PloS One
https://www.readbyqxmd.com/read/28922317/medical-genetic-services-in-a-developing-country-lesson-from-thailand
#9
Chanin Limwongse
PURPOSE OF REVIEW: To give an example of how advances in medical genetics impact a developing country and how Thailand struggle to improve medical genetics services. RECENT FINDINGS: Thailand is an example of developing country with limited resources, low geneticist to population ratio, formally decentralized even though practically centralized healthcare system and growing public interest in medical genetic technology. Nonetheless, efforts have been and still being made in regard to expanding clinical genetics services, improving access to laboratory diagnosis, increasing rare disease medication in national formulary, and training of medical genetics personnel...
September 16, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28922302/resident-knowledge-surgical-skill-and-confidence-in-transobturator-vaginal-tape-placement-the-value-of-a-cadaver-laboratory
#10
Woojin Chong, Keith Downing, Ava Leegant, Erika Banks, Dmitry Fridman, Sherry Downie
OBJECTIVES: The objective of this study is to examine the effect of additional cadaver laboratory use in training obstetrics and gynecology (OBGYN) residents on transobturator vaginal tape (TOT) insertion. METHODS: Thirty-four OBGYN residents were randomized into 2 groups (group 1, control; group 2, intervention; 17 in each group). Before and after the interventions, written knowledge and confidence levels were assessed. Both groups received didactic lectures using a bony pelvis and an instructional video on TOT insertion; group 2 participated in a half day cadaver laboratory...
September 15, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28922276/risk-factors-for-surgical-site-infection-after-posterior-lumbar-spinal-surgery
#11
Jia-Ming Liu, Hui-Lin Deng, Xuan-Yin Chen, Yang Zhou, Dong Yang, Man-Sheng Duan, Shan-Hu Huang, Zhi-Li Liu
STUDY DESIGN: A retrospective study. OBJECTIVE: The purpose of this study was to identify the independent risk factors for postoperative SSI after posterior lumbar spinal surgery based on the perioperative factors analysis. SUMMARY OF BACKGROUND DATA: Surgical site infection (SSI) is one of the most common complications after spinal surgery. Previous studies have identified different risk factors for postoperative SSI following lumbar spinal surgery...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28922264/validation-of-a-portable-coagulometer-for-routine-in-hospital-use-for-newborns
#12
Antonio E Jerez Calero, Dolores Fernández Jiménez, Manuel Molina Oya, Eduardo Narbona López, José Uberos Fernández
OBJECTIVES: To verify the reliability and clinical benefits of the coagulation tests made by a point of care device in newborn admitted to a neonatal unit. DESIGN: We made a statistical comparison between results obtained by the point of care device versus conventional laboratory analysis. SETTING: Level 3 neonatal unit. PATIENTS: Thirty-one infants admitted to the neonatal unit at the San Cecilio University Hospital (Granada, Spain) were recruited to this study...
September 15, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28922191/acr-spr-str-practice-parameter-for-the-performance-of-cardiac-positron-emission-tomography-computed-tomography-pet-ct-imaging
#13
Rathan M Subramaniam, Warren R Janowitz, Geoffrey B Johnson, Martin A Lodge, Marguerite T Parisi, Mark R Ferguson, Jeffrey C Hellinger, Gregory W Gladish, Narainder K Gupta
This clinical practice parameter has been developed collaboratively by the American College of Radiology (ACR), the Society for Pediatric Radiology (SPR), and the Society of Thoracic Radiology (STR). This document is intended to act as a guide for physicians performing and interpreting positron emission tomography-computed tomography (PET/CT) of cardiac diseases in adults and children. The primary value of cardiac PET/CT imaging include evaluation of perfusion, function, viability, inflammation, anatomy, and risk stratification for cardiac-related events such as myocardial infarction and death...
September 15, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28922103/budd-chiari-syndrome
#14
Tomáš Grus, Lukáš Lambert, Gabriela Grusová, Rohan Banerjee, Andrea Burgetová
Budd-Chiari syndrome (BCS) is a rare disease with an incidence of 0.1 to 10 per million inhabitants a year caused by impaired venous outflow from the liver mostly at the level of hepatic veins and inferior vena cava. Etiological factors include hypercoagulable conditions, myeloprolipherative diseases, anatomical variability of the inferior vena cava, and environmental conditions. Survival rates in treated patients range from 42 to 100% depending on the etiology and the presence of risk factors including parameters of Child-Pugh score, sodium and creatinine plasma levels, and the choice of treatment...
2017: Prague Medical Report
https://www.readbyqxmd.com/read/28922054/economic-burden-of-pneumococcal-infections-in-children-under-5%C3%A2-years-of-age
#15
Mehmet Ceyhan, Yasemin Ozsurekci, Kubra Aykac, Basak Hacibedel, Egemen Ozbilgili
The present study aimed to determine the cost of childhood pneumococcal infections under 5 years of age and to provide further data for future health economy studies. Electronic medical records of children diagnosed with meningitis caused by S. pneumoniae and all-cause pneumonia, and acute otitis media (AOM) between January 2013-April 2014 were retrospectively evaluated. Direct costs for the treatments of hospitalized patients (pneumonia and pneumococcal meningitis) including costs of healthcare services consisted of costs of hospital bed, examination, laboratory analyses, scanning methods, consultation, vascular access procedures, and infusion and intravenous treatments...
September 18, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28922052/applications-of-emerging-transmission-electron-microscopy-technology-in-pcd-research-and-diagnosis
#16
Amelia Shoemark
Primary Ciliary Dyskinesia (PCD) is a heterogeneous genetic condition characterized by dysfunction of motile cilia. Patients suffer from chronic infection and inflammation of the upper and lower respiratory tract. Diagnosis of PCD is confirmed by identification of a hallmark defect of ciliary ultrastructure or by identification of biallelic pathogenic mutations in a known PCD gene. Since the first description of PCD in 1976, assessment of ciliary ultrastructure by transmission electron microscopy (TEM) has been central to diagnosis and research...
September 18, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28921969/flow-electrolysis-cells-for-the-synthetic-organic-chemistry-laboratory
#17
Derek Pletcher, Robert A Green, Richard C D Brown
Electrosynthesis has much to offer to the synthetic organic chemist. But in order to be widely accepted as a routine procedure in an organic synthesis laboratory, electrosynthesis needs to be presented in a much more user-friendly way. The literature is largely based on electrolysis in a glass beaker or H-cells that often give poor performance for synthesis with a very slow rate of conversion and, often, low selectivity and reproducibility. Flow cells can lead to much improved performance. Electrolysis is participating in the trend toward continuous flow synthesis, and this has led to a number of innovations in flow cell design that make possible selective syntheses with high conversion of reactant to product with a single passage of the reactant solution through the cell...
September 18, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28921879/natural-and-artificial-mn4ca-cluster-for-water-splitting-reaction
#18
Chunxi Zhang, Changhui Chen, Yanxi Li, Guoqing Zhao, Ruoqing Yao
The oxygen-evolving center (OEC) in photosystem II (PSII) is a unique biological catalyst that splits water into electrons, protons and O2 by using solar energy. Recent crystallographic studies have revealed that the structure of the OEC is an asymmetric Mn4Ca-cluster, which provides a blueprint to develop man-made water-splitting catalysts in artificial photosynthesis. Although it is a great challenge to mimic the whole structure and function of the OEC in the laboratory, significant advances have recently been achieved...
September 17, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28921647/pharmacogenomics-implementation-at-the-national-institutes-of-health-clinical-center
#19
Tristan M Sissung, Jon W McKeeby, Jharana Patel, Juan J Lertora, Parag Kumar, Willy A Flegel, Sharon D Adams, Ellen J Eckes, Frank Mickey, Teri M Plona, Stephanie D Mellot, Ryan N Baugher, Xiaolin Wu, Daniel R Soppet, Mary E Barcus, Vivekananda Datta, Kristen M Pike, Gary DiPatrizio, William D Figg, Barry R Goldspiel
The National Institutes of Health Clinical Center (NIH CC) is the largest hospital in the United States devoted entirely to clinical research, with a highly diverse spectrum of patients. Patient safety and clinical quality are major goals of the hospital, and therapy is often complicated by multiple cotherapies and comorbidities. To this end, we implemented a pharmacogenomics program in 2 phases. In the first phase, we implemented genotyping for HLA-A and HLA-B gene variations with clinical decision support (CDS) for abacavir, carbamazepine, and allopurinol...
October 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28921603/trace-dna-sampling-success-from-evidence-items-commonly-encountered-in-forensic-casework
#20
Renata Dziak, Amy Peneder, Alicia Buetter, Cecilia Hageman
Trace DNA analysis is a significant part of a forensic laboratory's workload. Knowing optimal sampling strategies and item success rates for particular item types can assist in evidence selection and examination processes and shorten turnaround times. In this study, forensic short tandem repeat (STR) casework results were reviewed to determine how often STR profiles suitable for comparison were obtained from "handler" and "wearer" areas of 764 items commonly submitted for examination. One hundred and fifty-five (155) items obtained from volunteers were also sampled...
September 15, 2017: Journal of Forensic Sciences
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