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https://www.readbyqxmd.com/read/28637330/occurrence-of-aminoglycoside-modifying-enzymes-ames-among-isolates-of-escherichia-coli-exhibiting-high-levels-of-aminoglycoside-resistance-isolated-from-korean-cattle-farms
#1
Kuastros Mekonnen Belaynehe, Seung Won Shin, Park Hong-Tae, Han Sang Yoo
This study investigated 247 Escherichia coli isolates collected from four cattle farms to characterize aminoglycoside-modifying enzyme (AME) genes, their plasmid replicons and transferability. Out of 247 isolates a high number of isolates (total 202; 81.78%) were found resistant to various antibiotics by disc-diffusion. Of the 247 strains 139 (56.3%) were resistant to streptomycin and other antibiotics resistance followed as tetracycline (12.15%), ampicillin (7%), chloramphenicol (5.7%) and trimethoprim-sulfamethoxazole (0...
June 15, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28630628/staphylococcus-saprophyticus-recovered-from-humans-food-and-recreational-waters-in-rio-de-janeiro-brazil
#2
Viviane Santos de Sousa, Ana Paula de Souza da-Silva, Leif Sorenson, Raphael Paiva Paschoal, Renata Fernandes Rabello, Eloiza Helena Campana, Márcia Soares Pinheiro, Lyssa Oliveira Ferreira Dos Santos, Natacha Martins, Ana Carolina Nunes Botelho, Renata Cristina Picão, Sérgio Eduardo Longo Fracalanzza, Lee Woodland Riley, George Sensabaugh, Beatriz Meurer Moreira
Staphylococcus saprophyticus is an important agent of urinary tract infection (UTI) in young women, but information about this pathogen in human microbiota and in common environment is lacking. The aim of this study was to characterize S. saprophyticus isolates from genitoanal microbiota of 621 pregnant women, 10 minas cheese packs, and five beaches in Rio de Janeiro city and compare PFGE profiles of these isolates with five UTI PFGE clusters described in this city. We investigated 65 S. saprophyticus isolates from microbiota, 13 from minas cheese, and 30 from beaches and 32 UTI isolates...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/28630196/antimicrobial-susceptibility-trends-among-staphylococcus-aureus-from-united-states-hospitals-results-from-7-years-of-the-ceftaroline-aware-surveillance-program-2010-2016
#3
Helio S Sader, Rodrigo E Mendes, Jennifer M Streit, Robert K Flamm
We evaluated trends in Staphylococcus aureus antimicrobial susceptibility in United States hospitals in the 2010-2016 period. A total of 21,056 clinical isolates from 42 medical centers were tested for susceptibility by broth microdilution methods. MRSA rates decreased from 50.0% (2010) to 42.2% (2016). Susceptibility to erythromycin, levofloxacin, and clindamycin increased slightly, whereas susceptibility to ceftaroline, trimethoprim-sulfamethoxazole, and tetracycline remained stable. Ceftaroline retained potent activity against MSSA and MRSA (97...
June 19, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28629795/epidemiological-features-and-antibiotic-resistance-patterns-of-haemophilus-influenzae-originating-from-respiratory-tract-and-vaginal-specimens-in-pediatric-patients
#4
Jian-Ping Li, Chun-Zhen Hua, Li-Ying Sun, Hong-Jiao Wang, Zhi-Min Chen, Shi-Qiang Shang
BACKGROUND: Haemophilus influenzae (H. influenzae) is a common pathogen of respiratory tract infections in children, however, as a possible cause of vulvovaginitis in prepubertal girls, its epidemiological features,antibiotic-resistance patterns, and treatment are seldom noted. METHODS: Specimens obtained from patients were inoculated on Haemophilus selective medium; and drug-sensitivities tests were determined with disc diffusion method. Cefinase disc was used to detect β-lactamase...
June 16, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28629721/a-16-year-retrospective-surveillance-report-on-the-pathogenic-features-and-antimicrobial-susceptibility-of-pseudomonas-aeruginosa-isolates-from-fahju-in-guangzhou-representative-of-southern-china
#5
Jinhong Xie, Ling Yang, Brian M Peters, Lequn Chen, Dingqiang Chen, Bing Li, Lin Li, Guangchao Yu, Zhenbo Xu, Mark E Shirtliff
Pseudomonas aeruginosa is a major pathogen responsible for nosocomial infections. A 16-year retrospective report from 2000 to 2015 was conducted to assess the antimicrobial resistance of P. aeruginosa in Southern China. A total of 1387 P. aeruginosa were collected from inpatients and outpatients. Susceptibility testing results were interpreted according to the Clinical and Laboratory Standards Institute (CLSI, 2015). Piperacillin, piperacillin-tazobactam, ceftazidime, aminoglycosides and carbapenems remained to be active against P...
June 16, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28628813/removal-of-antibiotics-during-the-anaerobic-digestion-of-pig-manure
#6
Lu Feng, Mònica Escolà Casas, Lars Ditlev Mørck Ottosen, Henrik Bjarne Møller, Kai Bester
Antibiotics are frequently used in animals to treat sickness and prevent infection especially in industrial meat production. Some of the antibiotics cannot be completely metabolized and, as an unavoidable result, are excreted and thus end up in manure which is then spread in the environment. Currently increasing amounts of manure is used in biogas production before spreading the residuals on agricultural fields. In this study, the removal patterns of sulfonamides (sulfadiazine, sulfamethizole, sulfamethoxazole) and macrolides (clarithromycin, erythromycin), as well as trimethoprim, were investigated during the anaerobic digestion of pig manure...
June 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28627490/genotyping-and-antimicrobial-resistance-genes-of-yersinia-ruckeri-isolates-from-rainbow-trout-farms
#7
Muhammed Duman, Soner Altun, Murat Cengiz, Izzet Burcin Saticioglu, Ayse Gul Buyukekiz, Pinar Sahinturk
In this study, we compared 142 Yersinia ruckeri isolates collected between 2013 and 2016 from 6 different regions in Turkey. A total of 18 different genogroups were found, though most of the isolates clustered into the same genogroup as serotype O1. As immunization of fish with inactivated Y. ruckeri by injection, immersion, or feeding provide minimal protection against Y. ruckeri infection in Turkey, many fish producers use antimicrobials unrestrictedly, resulting in antimicrobial resistance in aquatic pathogens...
June 19, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/28626822/a-prospective-randomized-trial-of-azithromycin-versus-trimethoprim-sulfamethoxazole-in-treatment-of-toxoplasmic-retinochoroiditis
#8
Alireza Lashay, Ahmad Mirshahi, Najaf Parandin, Hamid Riazi Esfahani, Mehdi Mazloumi, Mohammad Reza Lashay, Mohammad Karim Johari, Elham Ashrafi
PURPOSE: To assess the efficacy of oral azithromycin in the treatment of toxoplasmic retinochoroiditis. METHODS: A randomized interventional comparative study was conducted on 14 patients with ocular toxoplasmosis who were treated with oral azithromycin and 13 patients who were treated with oral trimethoprim/sulfamethoxazole for 6-12 weeks. The achievement of treatment criteria in the two groups and lesion size reduction were considered as primary outcome measures...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28626609/detection-and-drug-resistance-profile-of-escherichia-coli-from-subclinical-mastitis-cows-and-water-supply-in-dairy-farms-in-saraburi-province-thailand
#9
Woranich Hinthong, Natapol Pumipuntu, Sirijan Santajit, Suphang Kulpeanprasit, Shutipen Buranasinsup, Nitat Sookrung, Wanpen Chaicumpa, Pisinee Aiumurai, Nitaya Indrawattana
Subclinical mastitis is a persistent problem in dairy farms worldwide. Environmental Escherichia coli is the bacterium predominantly responsible for this condition. In Thailand, subclinical mastitis in dairy cows is usually treated with various antibiotics, which could lead to antibiotic resistance in bacteria. E. coli is also a reservoir of many antibiotic resistance genes, which can be conveyed to other bacteria. In this study, the presence of E. coli in milk and water samples was reported, among which enteropathogenic E...
2017: PeerJ
https://www.readbyqxmd.com/read/28626538/septic-thrombophlebitis-with-persistent-methicillin-resistant-staphylococcus-aureus-bacteremia-and-de-novo-resistance-to-vancomycin-and-daptomycin
#10
Yael Koton, Zafrir Or, Naiel Bisharat
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with significant risk of mortality, especially when it occurs while on appropriate antimicrobial therapy. We herein describe an unusual case of a patient with prosthetic aortic tissue valve, who suffered from central venous catheter related MRSA bacteremia with septic thrombus formation in the superior vena cava. MRSA bacteremia persisted despite removal of the catheter and appropriate antimicrobial therapy including vancomycin, rifampin, and daptomycin...
May 31, 2017: Infectious Disease Reports
https://www.readbyqxmd.com/read/28621638/urologic-complications-after-renal-transplant-a-single-center-experience
#11
Hakan Sözen, Metin Onaran, Onur Özen, Aydın Dalgıç
OBJECTIVES: Urologic complications after kidney transplant are associated with significant morbidity, mortality, and prolonged hospital stay. An intervention or second surgical procedure is frequently required. Here, we report urologic complications in adult kidney recipients. MATERIALS AND METHODS: Since 2006, 171 adult kidney transplant procedures have been performed at the Gazi University Transplantation Center (Ankara, Turkey). Among these patients, there were 65 adult female (38%) and 106 adult male (62%) recipients...
June 16, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28618755/isolation-rates-and-antibiotic-susceptibilities-of-different-enterobacteriaceae-species-as-urinary-tract-infection-agents-in-turkey-a-systematic-review
#12
Caner Yürüyen, Yeşim Gürol, Sabire Ferda Kaleağasioğlu, Elif Çiğdem Kaspar, Gülden Yilmaz
BACKGROUND/AIM: In Turkey, few systematic reviews have analyzed the results of studies on the isolation rates of urinary tract infection agents and their antibiotic susceptibilities. This review was done to fill this gap and enable the correct application of guideline-based medical therapy by determining the isolation rates and antibiotic susceptibilities of different Enterobacteriaceae species in Turkey. MATERIALS AND METHODS: Relevant studies found from various databases with the help of previously specified search strategies were examined and eliminated according to eligibility criteria...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28616377/blue-after-splenectomy
#13
Taaran Cariappa Ballachanda Subbaiah, Jeremy P Feldman
INTRODUCTION: We present a 51 year old, African American, female who presented with persistent hypoxemia. She had been taking dapsone for many years for prophylaxis against Pneumocystic Jiroveci with no symptoms but eventually developed methemoglobinemia only after a splenectomy. From our literature review there are no documented cases that have demonstrated this relationship between dapsone, splenic function and methemoglobin and we hope to share our perplexing case and shed light on the interaction...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28615465/emergency-department-urinary-antibiograms-differ-by-specific-patient-groups
#14
S Jorgensen, M Zurayk, S Yeung, J Terry, M Dunn, P Nieberg, A Wong-Beringer
Background: Patients presenting to the ED represent a heterogeneous population comprised of all ages, from the community and skilled-nursing facilities (SNF), and at varying risk for resistant pathogens. The aim of this study was to compare patient group-specific urinary antibiograms in ED.Methods: Adults presented to ED with an ICD 9/10 UTI diagnosis during 7/15 - 6/16 were randomly selected (n=500) to extract relevant demographic, laboratory, and clinical data from the medical record. Urinary E. coli antibiograms were compared between: institutional vs...
June 14, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28614268/pulmonary-and-cutaneous-infection-caused-by-nocardia-farcinica-in-a-patient-with-nephrotic-syndrome-a-case-report
#15
Ning Zhu, Yuan Zhu, Yi Wang, Shaoshao Dong
RATIONALE: Nocardia species is known as conditional pathogenic bacteria. Disseminated infection caused by Nocardia species is rare and occurs primarily in immunosuppressed patients. Signs and symptoms of this infection are frequently nonspecific making early diagnosis and treatment difficult. PATIENT CONCERNS: We report a case of subcutaneous and pulmonary nocardiosis due to Nocardia farcinica (N farcinica) in a patient with nephrotic syndrome who is undergoing long-term corticosteroid therapy...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28614157/probable-donor-derived-cytomegalovirus-disease-after-keratolimbal-allograft-transplantation
#16
Albert Y Cheung, Amit Govil, Scott R Friedstrom, Edward J Holland
PURPOSE: To report a case of probable donor-derived cytomegalovirus (CMV) infection after keratolimbal allograft (KLAL) transplantation. METHODS: Observational case report. RESULTS: A 41-year-old man with a history of aniridic keratopathy and limbal stem cell deficiency underwent KLAL in his right eye. Preoperatively, he was negative for CMV IgG and IgM. Postoperatively, he was maintained on tacrolimus and mycophenolate mofetil for systemic immunosuppression; he was also on prophylactic valganciclovir (for CMV) and trimethoprim/sulfamethoxazole (for pneumocystis pneumonia) for 1 month...
June 13, 2017: Cornea
https://www.readbyqxmd.com/read/28606485/a-10-year-surveillance-of-antimicrobial-susceptibility-patterns-in-shigella-sonnei-isolates-circulating-in-jiangsu-province-china
#17
Bing Gu, Ting Xu, Haiquan Kang, Yanling Xu, Genyan Liu, Shiyang Pan, Huimin Qian, Ping Ma
OBJECTIVES: The rapid emergence of drug-resistant Shigella sonnei is a serious public health problem. This study aimed to characterise the antimicrobial resistance patterns, molecular subtypes, and integron types and resistance gene cassettes in S. sonnei from Jiangsu Province, China. METHODS: In total, 340 S. sonnei were collected in 2002-2011 throughout Jiangsu Province. Antimicrobial susceptibility testing, pulsed-field gel electrophoresis (PFGE), PCR amplification of integrons, restriction fragment length polymorphism (RFLP) and DNA sequencing of cassette regions were performed...
June 9, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28606284/-efficacy-of-clindamycin-primaquine-as-the-salvage-treatment-for-pneumocystis-pneumonia-in-non-hiv-infected-patients
#18
X Wang, G F Wang, Z Jin, J J Huang, X D Mu, W Zhang
Objective: To evaluate the efficacy of clindamycin-primaquine as the salvage treatment for pneumocystis pneumonia (PCP) in non-HIV-infected patients. Methods: Clinical data of non-HIV-infected patients with PCP who were treated with clindamycin-primaquine as the salvage treatment in Peking University First Hospital from Jan 2010 to May 2016 were collected and reviewed in this retrospective study. Clinical outcomes were analyzed to evaluate the efficacy of clindamycin-primaquine as a salvage treatment. Results: A total of 19 non-HIV-infected patients with PCP were included...
June 13, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28604274/routine-prophylactic-antimicrobial-use-is-associated-with-increased-phenotypic-and-genotypic-resistance-in-commensal-escherichia-coli-isolates-recovered-from-healthy-fattening-pigs-on-farms-in-thailand
#19
Kittitat Lugsomya, Thanitta Chatsuwan, Waree Niyomtham, Padet Tummaruk, David J Hampson, Nuvee Prapasarakul
This study examined antimicrobial resistance (AMR) profiles in commensal Escherichia coli derived from healthy fattening pigs in Thai farms that used prophylactic antimicrobials (in-feed tiamulin fumarate and amoxicillin) [PAs], therapeutic antimicrobials (injectable enrofloxacin or gentamicin) [TAs], or no antimicrobials [NAs]. Commensal E. coli were used as a proxy for overall AMR on the farms. There was a high level of multidrug resistance in all three categories of farm, with isolates showing resistance to β-lactams (amoxicillin, ampicillin, and piperacillin) and tetracyclines (tetracycline), and commonly possessing tetA, blaTEM, and plasmid replicons FIB and F...
June 12, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28603631/hepatic-expression-profiles-in-retroviral-infection-relevance-to-drug-hypersensitivity-risk
#20
Yat Yee Wong, Brian Johnson, Thomas C Friedrich, Lauren A Trepanier
HIV-infected patients show a markedly increased risk of delayed hypersensitivity (HS) reactions to potentiated sulfonamide antibiotics (trimethoprim/sulfamethoxazole or TMP/SMX). Some studies have suggested altered SMX biotransformation in HIV infection, but hepatic biotransformation pathways have not been evaluated directly. Systemic lupus erythematosus (SLE) is another chronic inflammatory disease with a higher incidence of sulfonamide HS, but it is unclear whether retroviral infection and SLE share risk factors for drug HS...
June 2017: Pharmacology Research & Perspectives
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