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José Luis Ruiz-Sandoval, María Eugenia Briseño-Godínez, Erwin Chiquete-Anaya, Antonio Arauz-Góngora, Rogelio Troyo-Sanromán, Juan Didier Parada-Garza, Alma Ramos-Moreno, Fernando Barinagarrementería, Luis Manuel Murillo-Bonilla, Carlos Cantú-Brito
BACKGROUND AND AIMS: Mortality and bad outcome by stroke are higher in developing countries than in industrialized countries. Health-care system efficiency could explain these disparities. Our objective was to identify the impact on short- and middle-term outcomes of patients with acute ischemic stroke (AIS) among public and private Mexican medical care. METHODS: We analyzed data from patients with AIS included in the Primer Registro Mexicano de Isquemia Cerebral (PREMIER) study...
February 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Sahar Askari, Alireza Imani, Hamidreza Sadeghipour, Mahdieh Faghihi, Zohreh Edalatyzadeh, Samira Choopani, Nasser Karimi, Sulail Fatima
Background: Cardiovascular diseases are the leading cause of mortality and long-term disability worldwide. Various studies have suggested a protective effect of lactation in reducing the risk of cardiovascular diseases. Objective: This study was designed to assess the effects of pregnancy and lactation on the vulnerability of the myocardium to an ischemic insult. Methods: Eighteen female rats were randomly divided into three groups: ischemia-reperfusion (IR), in which the hearts of virgin rats underwent IR (n = 6); lactating, in which the rats nursed their pups for 3 weeks and the maternal hearts were then submitted to IR (n = 6); and non-lactating, in which the pups were separated after birth and the maternal hearts were submitted to IR (n = 6)...
May 2017: Arquivos Brasileiros de Cardiologia
Rafael Alexandre Meneguz-Moreno, José de Ribamar Costa, Freddy Antônio Britto Moscoso, Rodolfo Staico, Luiz Fernando Leite Tanajura, Marinella Patrizia Centemero, Auréa Jacob Chaves, Andrea Claudia Leão de Sousa Abizaid, Amanda Guerra de Moraes Rego E Sousa, Alexandre Antonio Cunha Abizaid
Background: Bioresorbable vascular scaffolds (BVS) were developed to improve the long-term results of percutaneous coronary intervention, restoring vasomotion. Objectives: To report very late follow-up of everolimus-eluting Absorb BVS (Abbott Vascular, Santa Clara, USA) in our center. Methods: Observational retrospective study, in a single Brazilian center, from August 2011 to October 2013, including 49 patients submitted to Absorb BVS implantation...
February 2017: Arquivos Brasileiros de Cardiologia
Igor Nagai Yamaki, Ruy Victor Simões Pontes, Felipe Lobato DA Silva Costa, Vitor Nagai Yamaki, Renan Kleber Costa Teixeira, Edson Yuzur Yasojima, Marcus Vinicius Henriques Brito
Objective: to evaluate the effects of blocking the regulation of vascular tone on the ischemia and reperfusion syndrome in rats through the use of lidocaine in the postconditioning technique. Methods: we randomized 35 rats into seven groups of five animals: Group 1- Control; Group 2- Ischemia and Reperfusion; Group 3- Ischemia, Reperfusion and Saline; Group 4- Ischemic Postconditioning; Group 5- Ischemic Postconditioning and Saline; Group 6- Lidocaine; Group 7- Ischemic Postconditioning and Lidocaine...
September 2016: Revista do Colégio Brasileiro de Cirurgiões
Costantino Roberto Frack Costantini, Jose Antonio Ramires, Costantino Ortiz Costantini, Marcos Antonio Denk, Sergio Gustavo Tarbine, Marcelo de Freitas Santos, Daniel Aníbal Zanuttini, Carmen Weigert Silveira, Admar Moraes de Souza, Rafael Michel de Macedo
BACKGROUND: Functional assessment of coronary artery obstruction is used in cardiology practice to correlate anatomic obstructions with flow decrease. Among such assessments, the study of the coronary fractional flow reserve (FFR) has become the most widely used. OBJECTIVE: To evaluate the correlation between FFR and findings of ischemia obtained by noninvasive methods including stress echocardiography and nuclear medicine and the presence of critical coronary artery obstruction...
January 2017: Arquivos Brasileiros de Cardiologia
Douglas Bastos Neves, Marcela Balbo Rusi, Luiz Gustavo Guedes Diaz, Paolo Salvalaggio
Primary graft dysfunction is a multifactorial syndrome with great impact on liver transplantation outcomes. This review article was based on studies published between January 1980 and June 2015 and retrieved from PubMed database using the following search terms: "primary graft dysfunction", "early allograft dysfunction", "primary non-function" and "liver transplantation". Graft dysfunction describes different grades of graft ischemia-reperfusion injury and can manifest as early allograft dysfunction or primary graft non-function, its most severe form...
2016: Einstein
Esbeidira Aranet Arroyo-Martínez, Alejandra Meaney, Gabriela Gutiérrez-Salmeán, Juan Miguel Rivera-Capello, Vidal González-Coronado, Alejandro Alcocer-Chauvet, Genaro Castillo, Nayelli Nájera, Guillermo Ceballos, Eduardo Meaney
BACKGROUND: Remote ischemic preconditioning (RIPC) represents an attractive therapy for myocardial protection, particularly when ischemic events can be anticipated. Although several hypothetic mechanisms have been proposed, no definite molecular pathways have been elucidated. OBJECTIVE: We evaluated the effect of brachial circulation cuff occlusion on myocardial ischemic tolerance, necrosis, and nitric oxide (NO) in patients with ischemic heart disease undergoing elective percutaneous coronary interventions (PCI)...
August 2016: Arquivos Brasileiros de Cardiologia
Elisa Santacruz-Cerdán, Karina Arcano, Francisco Arrieta Blanco, Andrés Ortiz Flores, Raquel Mateo Lobo, José Ignacio Botella Carretero, Clotilde Vázquez Martínez, Isabel Zamarrón Cuesta
The use of home parenteral nutrition (HPN) in patients who can not obtain their nutritional requirements by the enteral route is increasing in recent years, allowing normalization lifestyle of patients. Neoplasm and mesenteric ischaemia are some of the diseases that most frequently require HPN in Spain. However, HPN is one of the cornerstones of the treatment of much less frequent illnesses as in the case of encapsulating peritoneal sclerosis. We present the case of a patient with encapsulating peritoneal sclerosis and HPN support for more than 7 years with a peripherally inserted central catheter (PICC) for over 6 years without complications and the autonomy to perform his normal business activity...
February 16, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Ángela Sala-Hernández, Salvador Pous-Serrano, Elí Lucas-Mera, Nicolás Carvajal-Amaya
Acute colonic volvulus accounts for 10% of all intestinal obstructions being the transverse colon volvulus an exceptional localization (2-4%). Late diagnosis is made as there are no pathognomonic clinical or radiological findings for this pathology. We present the case of an 81 year-old male with acute transverse colon volvulus that involved the gastric antrum causing irreversible ischemia. Subtotal gastrectomy, subtotal colectomy and reconstruction with Y en Roux gastrojejunostomy and ileosigmoid anastomosis was performed given the good overall status of the patient...
March 2016: Revista Española de Enfermedades Digestivas
Pedro Elias Marques, André Gustavo Oliveira, Lynne Chang, Heitor Affonso Paula-Neto, Gustavo Batista Menezes
The liver has come a long way since it was considered only a metabolic organ attached to the gastrointestinal tract. The simultaneous ascension of immunology and intravital microscopy evidenced the liver as a central axis in the immune system, controlling immune responses to local and systemic agents as well as disease tolerance. The multiple hepatic cell populations are organized in a vascular environment that promotes intimate cellular interactions, including initiation of innate and adaptive immune responses, rapid leukocyte recruitment, pathogen clearance and production of a variety of immune mediators...
September 2015: Journal of Hepatology
Mara Graziele Maciel Silveira, Antônio Carlos Sobral Sousa, Marcos Antônio Almeida Santos, Irlaneide da Silva Tavares, Stephanie Macedo Andrade, Luiza Dantas Melo, Loren Suyane Oliveira de Andrade, Emmanuel Lima Almeida Santos, Joselina Luzia Menezes Oliveira
BACKGROUND: Physical stress echocardiography is an established methodology for diagnosis and risk stratification of coronary artery disease in patients with physical capacity. In obese (body mass index ≥ 30 kg/m2) the usefulness of pharmacological stress echocardiography has been demonstrated; however, has not been reported the use of physical stress echocardiography in this growing population group. OBJECTIVE: To assess the frequency of myocardial ischemia in obese and non-obese patients undergoing physical stress echocardiography and compare their clinical and echocardiographic differences...
May 2015: Arquivos Brasileiros de Cardiologia
Ana Carla Pereira de Araujo, Bruno F de Oliveira Santos, Flavia Ricci Calasans, Ibraim M Francisco Pinto, Daniel Pio de Oliveira, Luiza Dantas Melo, Stephanie Macedo Andrade, Irlaneide da Silva Tavares, Antonio Carlos Sobral Sousa, Joselina Luzia Menezes Oliveira
Background: Studies have demonstrated the diagnostic accuracy and prognostic value of physical stress echocardiography in coronary artery disease. However, the prediction of mortality and major cardiac events in patients with exercise test positive for myocardial ischemia is limited. Objective: To evaluate the effectiveness of physical stress echocardiography in the prediction of mortality and major cardiac events in patients with exercise test positive for myocardial ischemia. Methods: This is a retrospective cohort in which 866 consecutive patients with exercise test positive for myocardial ischemia, and who underwent physical stress echocardiography were studied...
October 28, 2014: Arquivos Brasileiros de Cardiologia
C León-Jiménez, J L Ruiz-Sandoval, E Chiquete, M Vega-Arroyo, A Arauz, L M Murillo-Bonilla, A Ochoa-Guzmán, K Carrillo-Loza, A Ramos-Moreno, F Barinagarrementeria, C Cantú-Brito
INTRODUCTION: Information regarding hospital arrival times after acute ischaemic stroke (AIS) has mainly been gathered from countries with specialised stroke units. Little data from emerging nations is available. We aim to identify factors associated with achieving hospital arrival times of less than 1, 3, and 6 hours, and analyse how arrival times are related to functional outcomes after AIS. METHODS: We analysed data from patients with AIS included in the PREMIER study (Primer Registro Mexicano de Isquemia Cerebral) which defined time from symptom onset to hospital arrival...
May 2014: Neurología: Publicación Oficial de la Sociedad Española de Neurología
Joana Mota, Amparo Castellano, Felicidade Santiago, Patrícia Carvalho, A Sofia Madeira, J M Pereira De Moura, J M Nascimento Costa
INTRODUCTION: Systemic sclerosis (SSc) is a systemic disease, characterized by fibrosis and vasculopathy, with variable internal organ involvement. Skin is very often involved, namely digital ulcers (DU), seldom treatment resistant, responsible for important functional limitation. The DU can evolve from sclerodactily with superficial ulcers, isquemic lesions, deep necrosis, gangrene, loss of tissue, and consequently, to finger amputation. METHODS: The authors describe the case of a 36 year old female patient, with SSc diagnosed 6 years previously, with skin, lung and gut manifestations...
September 2011: Acta Médica Portuguesa
Natalia Lausada, Pablo Stringa, Ana Cabanne, Diego Ramisch, Mariana Machuca, Flavio Galvao, Silvia Coronato, Jorge Clemente Raimondi, Gabriel Gondolesi
INTRODUCTION: The intestine is a highly sensitive tissue to ischemia-reperfusion (IR) injury that will early respond increasing its permeability. Later this response is translated in morphologic and histological changes that reveal the degree of damage. The heterotopic intestinal transplantation model in rats allows to evaluate the evolution of intestinal tissue injury after ischemia-reperfusion without affecting the long survival rate. OBJECTIVE: The aim of this paper is to establish a relationship between the ischemic reperfusion injury with the long-term survival METHODS: Ten intestinal transplants were analyzed in adult, Wistar, inbred, male rats...
June 2011: Acta Gastroenterologica Latinoamericana
B Tarazona, W Ramos, J Arce, J Yarinsueca, S Morales, G Ronceros, C Galarza, J Pérez
INTRODUCTION: To determinate the etiology and risk factors for a first episode of cerebral ischemia in young adults at three hospitals of Lima and Callao-Peru. METHODS: Multicentric study carried out at three national hospitals in Lima. The sample included 30 patients with a first episode of stroke and 60 controls matched by age and sex 2:1 with the patients. Serum biochemistry studies, EKGs and echocardiograms were done. Etiologies were classified based on the classification of Baltimore-Washington Cooperative Young Stroke Study...
October 2010: Neurología: Publicación Oficial de la Sociedad Española de Neurología
Alexandre Coutinho Teixeira de Freitas, Mônica Beatriz Parolin, Lucinei Stadnik, Júlio Cezar Uili Coelho
BACKGROUND: Liver transplantation is the main treatment option for hepatocellular carcinoma in patients with cirrhosis. AIM: Three months and 3 years survival were analysed in patients with cirrhosis and hepatocellular carcinoma and in patients with only cirrhosis. METHODS: Charts of patients subjected to cadaveric liver transplantation at the Clinical Hospital of the Federal University of Paraná, Curitiba, PR, Brazil, between January 5th of 2001 and February 17th of 2006 were reviewed...
July 2007: Arquivos de Gastroenterologia
Jaume Marrugat, Roberto Elosua, Elena Aldasoro, María José Tormo, Hermelinda Vanaclocha, Antonio Segura, Miquel Fiol, Concepción Moreno-Iribas, Gloria Pérez, José María Arteagoitia, Lluis Cirera, Adolfo Cabadés, Gema Vega, José Ignacio Ayestarán, Vega García, Iraida Hurtado-de-Saracho, José García, Oscar Zurriaga, Javier Muñiz, Joan Sala
BACKGROUND: Myocardial infarction (MI) incidence and mortality display a high geographic variation. AIMS: The objective of the present study was to analyze MI mortality, cumulative incidence rate variability in seven regions of Spain from 1997 to 1998. METHODS AND RESULTS: Standardized methods were used to identify, find, register, and classify MI cases that were classified as definite, possible, insufficient-data MI, and non-MI. The total population of the seven monitored regions was 7,364,682 inhabitants...
2004: European Journal of Epidemiology
D A Martínez, J l Aguayo, G Morales, M l Aguirán, F Illán
OBJECTIVE: The ulcers, infections and isquemia of the foot are the main causes of hospitalisation of the diabetic patient and, very frequently, they are reason for the amputation of the limb. The objective of this investigation consists of evaluating the results of a multidisciplinary clinical pathway designed by the set of specialists of different departments from our hospital, as well as of the associated personnel of infirmary, implied in the management of this pathology. PATIENTS AND METHODS: We have analysed the evolution of a series of clinical and socio-economic indicators comparing, in the patients admitted with diagnose of complicated diabetic foot, the previous period to the implantation of the clinical pathway years 1998, 1999 and 2000) with the later period to this implantation (years 2001 and 2002)...
September 2004: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna
R Barrero Candau, M P Pérez Espejo, M A Gentil Govantes, F J Torrubia Romero, N Cruz Navarro, J Leal Arenas, P Montañés Medina
UNLABELLED: FUNDAMENTAL: [corrected] To know which risk factor of delayed graft function in our patients. MATERIAL AND METHODS: We analyzed 469 transplants, 270 had good initial function and 199 had delayed function graft. Variables studies in booth groups were: age, sex and dead cause of donant, type of extraction and place were it was done, implantation side, vases multiple, isquemia times, age and receptor sex, HLA compatibility, retransplant, Ac Anti-VHC, PTH pretransplant, years in waiting list, hiperinmunization, number of transfusion, and type of inmunosupretion...
July 2003: Actas Urologicas Españolas
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