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https://www.readbyqxmd.com/read/29350629/conductive-films-of-silver-nanoparticles-as-novel-susceptors-for-induction-welding-of-thermoplastic-composites
#1
Rouhollah Dermanaki Farahani, Mathieu Janier, Martine Dubé
In the present work, a conductive film of silver nanoparticles (nAg) as a novel heating element type, called susceptor was developed and tested for induction welding of carbon fiber/polyphenylene sulfide (CF/PPS) thermoplastic composites, i.e., unidirectional pre-impregnated16 plies of CF/PPS compression-molded in a quasi-isotropic stacking sequence. The nAg were synthesized, dispersed in deionized (DI) water and casted onto a pure PPS film, resulting in a conductive film upon the evaporation of DI water and thermal post-annealing...
January 19, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29346345/the-cytosolic-sensor-sting-is-required-for-intestinal-homeostasis-and-control-of-inflammation
#2
M C C Canesso, L Lemos, T C Neves, F M Marim, T B R Castro, É S Veloso, C P Queiroz, J Ahn, H C Santiago, F S Martins, J Alves-Silva, E Ferreira, D C Cara, A T Vieira, G N Barber, S C Oliveira, A M C Faria
STING (stimulator of interferon genes) is a cytosolic sensor for cyclic dinucleotides and also an adaptor molecule for intracellular DNA receptors. Although STING has important functions in the host defense against pathogens and in autoimmune diseases, its physiological relevance in intestinal homeostasis is largely unknown. In this study, we show that STING-/- mice presented defective protective mechanisms of intestinal mucosa, including decreased number of goblet cells, diminished mucus production, and lower levels of secretory IgA, when compared with wild-type (WT) mice...
December 20, 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/29345552/preceding-race-efforts-affect-pacing-and-short-track-speed-skating-performance
#3
Marco J Konings, Florentina J Hettinga
PURPOSE: In real-life competitive situations, athletes are required to continuously make decisions about how and when to invest their available energy resources. This study attempted to identify how different competitive environments invite elite short-track speed skaters to modify their pacing behaviour during head-to-head competition. METHODS: Lap times of elite 500, 1000 and 1500 m short-track speed skating competitions between 2011-2016 (n=34095 races) were collected...
January 18, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29345402/association-of-long-term-glycaemic-control-on-tear-break-up-times-and-dry-eye-symptoms-in-chinese-patients-with-type-2-diabetes
#4
Andre Ma, Martin Sy Mak, Kendrick Co Shih, Claudia Ky Tsui, Rachel Ky Cheung, Sherman Haynam Lee, Hubert Leung, Joyce Ns Leung, Jason Th Leung, Marco Zhenji Van-Boswell, Michael Tl Wong, Alex Lap-Ki Ng, Chi-Ho Lee, Vishal Jhanji, Louis Tong
Importance Diabetes mellitus is known to be associated with dry eye syndrome (DES), but the effects of long term glycaemic control on tear film metrics and dry eye symptoms are not known in the Chinese population. BACKGROUND: To evaluate tear film stability and dry eye symptoms and their associations with systemic risk factors in Chinese patients with type 2 diabetes (T2DM) Design Cross-sectional study set at the Lo Fong Siu Po Eye Centre (Grantham Hospital), Hong Kong.
January 18, 2018: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29344963/refractory-pulmonary-edema-and-upper-body-hypoxemia-during-veno-arterial-extracorporeal-membrane-oxygenation-a-case-for-atrial-septostomy
#5
Amit Prasad, Ali Ghodsizad, Christoph Brehm, Mark Kozak, Michael Körner, Aly El Banayosy, Kai Singbartl
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides mechanical circulatory support for patients with advanced cardiogenic shock, facilitating myocardial recovery and limiting multi-organ failure. In patients with severely limited left ventricular ejection, peripheral VA-ECMO can further increase left ventricular and left atrial pressures (LAP). Failure to decompress the left heart under these circumstances can result in pulmonary edema and upper body hypoxemia, that is, myocardial and cerebral ischemia...
January 18, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29343411/consequence-of-enhanced-lc3-trafficking-for-a-live-attenuated-m-tuberculosis-vaccine
#6
Stefan Köster, Thais Klevorn, Kadamba Papavinasasundaram, Christopher M Sassetti, Cynthia Portal-Celhay, Jennifer A Philips
Development of a new vaccine against tuberculosis is urgently needed. Recent work has demonstrated that two related LC3-associated trafficking pathways, autophagy and LC3-associated phagocytosis (LAP), enhance antigen presentation and might play a role in vaccine efficacy. Mycobacterium tuberculosis inhibits both LC3-trafficking pathways. Moreover, the vaccine strain, BCG, induces even less LC3-trafficking than M. tuberculosis, which may help explain its limited efficacy. To determine whether enhanced LC3-trafficking can improve efficacy of a live, attenuated M...
January 15, 2018: Vaccine
https://www.readbyqxmd.com/read/29343172/quantification-of-brake-data-acquired-with-a-brake-power-meter-during-simulated-cross-country-mountain-bike-racing
#7
Matthew C Miller, Philip W Fink, Paul W Macdermid, Stephen R Stannard
There is currently a dearth of information describing cycling performance outside of propulsive and physiological variables. The aim of the present study was to utilise a brake power meter to quantify braking during a multi-lap cross-country mountain bike time trial and to determine how braking affects performance. A significant negative association was determined between lap time and brake power (800.8 ± 216.4 W, mean ± SD; r = -0.446; p < 0.05), while the time spent braking (28.0 ± 6.4 s) was positively associated with lap time (314...
January 17, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29338918/filling-pressures-in-fontan-revisited-comparison-between-pulmonary-artery-wedge-ventricular-end-diastolic-and-left-atrial-pressures-in-adults
#8
William R Miranda, Alexander C Egbe, Donald J Hagler, Nathaniel W Taggart, Rick A Nishimura, Heidi M Connolly, Carole A Warnes
BACKGROUND: Pulmonary artery wedge pressure (PAWP) has been shown to correlate better with left atrial pressure (LAP) than ventricular end-diastolic pressure (VEDP) in acquired heart disease. The correlation between VEDP and PAWP and their performance as surrogates for LAP in Fontan patients is unknown. METHODS: Offline single-beat simultaneous measurement of PAWP and VEDP was performed in 50 adult Fontan patients and non-simultaneous hemodynamic data abstracted for calculation of pulmonary vascular resistance (PVR)...
December 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29338126/physical-exercise-and-glaucoma-a-review-on-the-roles-of-physical-exercise-on-intraocular-pressure-control-ocular-blood-flow-regulation-neuroprotection-and-glaucoma-related-mental-health
#9
REVIEW
Ming Ming Zhu, Jimmy Shiu Ming Lai, Bonnie Nga Kwan Choy, Jennifer Wei Huen Shum, Amy Cheuk Yin Lo, Alex Lap Ki Ng, Jonathan Cheuk Hung Chan, Kwok Fai So
The benefits of physical exercise on health and well-being have been studied in a wide range of systemic and ocular diseases, including glaucoma, a progressive optic neuropathy characterized by accelerated apoptosis of retinal ganglion cells (RGCs). Elevated intraocular pressure (IOP) and insufficient ocular perfusion have been postulated to be the two main theories in glaucoma development and progression. The effects of exercise in these two aspects have been demonstrated by numerous researches. A review in 2009 focusing on these two theories concluded that exercise results in transient IOP reduction but an inconsistent elevation in ocular perfusion...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29332171/long-term-patient-related-outcome-measures-of-septoplasty-a-systematic-review
#10
REVIEW
Chi Lap Nicholas Tsang, Theresa Nguyen, Torunn Sivesind, Anders Cervin
PURPOSE: Septoplasty is a common rhinological procedure intended to relieve symptoms of chronic nasal obstruction. However, there remains a question as to whether patients obtain symptom improvement and are satisfied with surgical outcomes in the months and years after septoplasty. This review aims to evaluate the long-term efficacy of functional septoplasty for nasal septal deviation. METHODS: A systematic review of the literature was conducted from November 2014 to March 2016 using the Cochrane, EMBASE, and PubMed databases...
January 13, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29331957/mitral-valve-anatomic-predictors-of-hemodynamic-success-with-transcatheter-mitral-valve-repair
#11
Jeremy J Thaden, Joseph F Malouf, Vuyisile T Nkomo, Sorin V Pislaru, David R Holmes, Guy S Reeder, Charanjit S Rihal, Mackram F Eleid
BACKGROUND: Mitral regurgitation is a heterogeneous disease. Determining which patients derive optimal outcomes from transcatheter edge-to-edge mitral valve repair (TMVR) remains challenging. We sought to determine whether baseline mitral valve anatomic characteristics are predictive of left atrial pressure (LAP) changes during TMVR with MitraClip. METHODS AND RESULTS: Consecutive patients with severe mitral regurgitation undergoing TMVR (n=112) underwent continuous intraprocedural LAP monitoring and retrospective echocardiographic analysis for specific mitral anatomic characteristics...
January 13, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29331340/hsp72-protects-from-liver-injury-via-attenuation-of-hepatocellular-death-oxidative-stress-and-jnk-signaling
#12
Kateryna Levada, Nurdan Guldiken, Xiaoji Zhang, Giovanna Vella, Fa-Rong Mo, Laura P James, Johannes Haybaeck, Sonja M Kessler, Alexandra K Kiemer, Thomas Ott, Daniel Hartmann, Norbert Hüser, Marianne Ziol, Christian Trautwein, Pavel Strnad
BACKGROUND AND AIMS: Heat shock protein (Hsp) 72 is a molecular chaperone that is upregulated in response to stress and possesses broad cytoprotective functions. To determine its hepatic function, we studied its expression in human liver disorders and its biological significance in newly generated transgenic animals. AIM AND METHODS: Double transgenic mice overexpressing Hsp72 (gene HSPA1A) under the control of a tissue-specific tetracycline-inducible system (Hsp72-LAP mice) were produced...
January 10, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29330941/hydrophobic-and-hydrophilic-effects-on-water-structuring-and-adhesion-in-denture-adhesives
#13
Simrone K Gill, Nima Roohpour, Yiran An, Julien E Gautrot, Paul D Topham, Brian J Tighe
Denture adhesives are designed to be moisture-sensitive through the inclusion of a blend of polymer salts with varying degrees of water-sensitivity. This enables the adhesive to mix with saliva in vivo and activate its high tack, through the formation of a mucilaginous layer. We report for the first time, the use of differential scanning calorimetry (DSC) to study a series of hydrophobic and hydrophilic polymeric systems in order to correlate water-structuring behavior with adhesion strength. Adhesive bonding of the more hydrophobic variants was higher than that of a commercial-based control and a more hydrophilic polymer system in both lap shear and tensile configurations...
January 13, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29330837/computer-simulated-modeling-of-healthy-and-diseased-right-ventricular-and-pulmonary-circulation
#14
Jody Chou, Joseph B Rinehart
We have previously developed a simulated cardiovascular physiology model for in-silico testing and validation of novel closed-loop controllers. To date, a detailed model of the right heart and pulmonary circulation was not needed, as previous controllers were not intended for use in patients with cardiac or pulmonary pathology. With new development of controllers for vasopressors, and looking forward, for combined vasopressor-fluid controllers, modeling of right-sided and pulmonary pathology is now relevant to further in-silico validation, so we aimed to expand our existing simulation platform to include these elements...
January 12, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29330042/differences-in-the-ct-findings-between-vulnerable-plaque-and-culprit-lesions-in-acute-coronary-syndrome
#15
Eun Ju Chun, Jin Hee Han, Seung Min Yoo, Hwa Yeon Lee, In Sup Song, Charles S White
BACKGROUND: The CT finding of "vulnerable plaque" is widely regarded as similar to that of a culprit lesion in an acute coronary syndrome (ACS). However, this hypothesis may not be accurate, since "vulnerable plaques" may substantially change their morphology when they rupture to cause an ACS. METHODS: We retrospectively evaluated coronary CT angiography data sets of 25 patients with ACS who had vulnerable (n = 10) or culprit plaques (n = 15). We analyzed CT features including positive remodeling (PR), low attenuation plaque (LAP), the napkin ring sign (NRS), degree of stenosis (normal, <50%, 50-99%, 100%), and myocardial hypoperfusion in the left ventricle...
January 5, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29329981/molecular-cloning-and-characterization-of-leucine-aminopeptidase-gene-from-taenia-pisiformis
#16
Shaohua Zhang, Xuepeng Cai, Xuenong Luo, Shuai Wang, Aijiang Guo, Junling Hou, Run Wu
Leucine aminopeptidase (LAP, EC: 3.4.11.1) is an important metalloexopeptidase that catalyze the hydrolysis of amino-terminal leucine residues from polypeptides and proteins. In this study, a full length of cDNA encoding leucine aminopeptidase of Taenia pisiformis (TpLAP) was cloned by rapid amplification of cDNA-ends using the polymerase chain reaction (RACE-PCR) method. The full-length cDNA of the TpLAP gene is 1823 bp and contains a 1569 bp ORF encoding 533 amino acids with a putative mass of 56.4 kDa...
January 9, 2018: Experimental Parasitology
https://www.readbyqxmd.com/read/29328215/cascaded-four-wave-mixing-in-the-xuv-region
#17
Lap Van Dao, Khoa Anh Tran, Peter Hannaford
We present a detailed study of the wave-mixing process in the extreme ultraviolet (XUV) region (around 30 nm) by using two collinear multiple-cycle laser pulses with incommensurate frequencies (wavelengths 1400 and 800 nm). The experimental data provide evidence for the coherent accumulation of wave-mixing fields and a high third-order response of the medium in this spectral range. We show that the time evolution of the mixing fields can be used to study the coherence dynamics of the free-electron wave packet with a lifetime of 200-750 fs...
January 1, 2018: Optics Letters
https://www.readbyqxmd.com/read/29327655/accuracy-between-optical-and-inertial-motion-capture-systems-for-assessing-trunk-speed-during-preferred-gait-and-transition-periods
#18
Martin Kokholm Fleron, Niels Christian Hauerbach Ubbesen, Francesco Battistella, David Leandro Dejtiar, Anderson Souza Oliveira
Motion capture through inertial sensors is becoming popular, but its accuracy to describe kinematics during changes in walking speed is unknown. The aim of this study was to determine the accuracy of trunk speed extracted using an inertial motion system compared to a gold standard optical motion system, during steady walking and stationary periods. Eleven participants walked on pre-established paths marked on the floor. Between each lap, a 1-second stationary transition period at the initial position was included prior to the next lap...
January 12, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29327029/bio-inspired-robust-non-iridescent-structural-color-with-self-adhesive-amorphous-colloidal-particle-arrays
#19
Panmiao Liu, Jialun Chen, Zexi Zhang, Zhuoying Xie, Xin Du, Zhongze Gu
Here we propose a new method for constructing highly color fast non-iridescent structural color materials by assembling self-adhesive poly-dopamine coated SiO2 nanoparticles (PDA@SiO2) for amorphous colloidal arrays through a "spraying" process. Simply by alkaline vapor treatment, the adhesive forces and fastness of the amorphous colloidal arrays were significantly improved. This was demonstrated by lap shear tests of tape tearing and cohesive failure as well as a series of fastness tests like sandpaper abrasion, finger wiping and ultrasonic cleaning...
January 12, 2018: Nanoscale
https://www.readbyqxmd.com/read/29322661/utility-of-three-novel-insulin-resistance-related-lipid-indexes-for-predicting-type-2-diabetes-mellitus-among-people-with-normal-fasting-glucose-in-rural-china
#20
Bingyuan Wang, Ming Zhang, Yu Liu, Xizhuo Sun, Lu Zhang, Chongjian Wang, Li Linlin, Yongcheng Ren, Chengyi Han, Yang Zhao, Junmei Zhou, Chao Pang, Lei Yin, Tianping Feng, Jingzhi Zhao, Dongsheng Hu
BACKGROUND: Inexpensive and easily measurable indexes are needed to predict type 2 diabetes mellitus (T2DM) early in rural areas of China. We aimed to compare triglyceride glucose (TyG), visceral adiposity (VAI), and lipid accumulation product (LAP) along with traditional individual measures and their ratios for predicting T2DM. METHODS: Data for 11,113 people with baseline normal fasting glucose in a rural Chinese cohort were followed for a median of 6.0 years...
January 11, 2018: Journal of Diabetes
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