Víctor Pérez, Gloria Villalba-Martínez, Matilde Elices, Rosa María Manero, Purificación Salgado, José María Ginés, Rocío Guardiola, Carlos Cedrón, María Polo, Ignacio Delgado-Martínez, Gerardo Conesa, Santiago Medrano, Maria J Portella
BACKGROUND: Up to 20% of the cases of anorexia nervosa (AN) are chronic and treatment-resistant. Recently, the efficacy of deep brain stimulation (DBS) for severe cases of AN has been explored, with studies showing an improvement in body mass index and other psychiatric outcomes. While the effects of DBS on cognitive domains have been studied in patients with other neurological and psychiatric conditions so far, no evidence has been gathered in AN. METHODS: Eight patients with severe, chronic, treatment-resistant AN received DBS either to the nucleus accumbens (NAcc) or subcallosal cingulate (SCC; four subjects on each target)...
July 2022: European Eating Disorders Review: the Journal of the Eating Disorders Association