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https://www.readbyqxmd.com/read/27925295/parents-perceptions-are-that-their-child-s-health-related-quality-of-life-is-more-impaired-when-they-have-a-wheat-rather-than-a-grass-allergy
#1
Nora Borres, Nora Nilsson, Isabel Drake, Sigrid Sjölander, Caroline Nilsson, Gunilla Hedlin, Björn Nordlund
AIM: It is unknown whether food allergies have greater impact on quality of life than respiratory allergies. This study compared health-related quality of life (HRQoL) in children allergic to wheat or grass. METHODS: We surveyed 63 children with wheat allergies (median age of five) and 72 with grass allergies (median age 12), with their parents. The Child Health Questionnaires for parents (CHQ-PF28) and children (CHQ-CF87) were applied. RESULTS: The parents of children in the wheat group recorded significantly lower CHQ-PF28 scores for the impact of their child's allergy on general behaviour, general health perceptions, parental impact of emotions and time and family activities, than the parents of children with grass allergies (p values <0...
December 7, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27923649/food-allergy-trends-and-epinephrine-autoinjector-presence-in-summer-camps
#2
Natalie R Schellpfeffer, Harvey L Leo, Michael Ambrose, Andrew N Hashikawa
BACKGROUND: Pediatric campers with food allergies are at greater risk for exposure and anaphylaxis. A diagnosis of asthma increases risk for anaphylaxis. Epidemiological investigations of food-allergic children at high risk for allergic reactions requiring intervention in camp settings are lacking. OBJECTIVE: The objectives of this study were to estimate the prevalence of food allergies among otherwise healthy campers in summer camps throughout the United States and Canada, and to assess asthma comorbidity and determine rates of epinephrine autoinjector prescriptions present in this population...
December 3, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27922230/consensus-statement-on-diagnosis-treatment-and-follow-up-of-cow-s-milk-protein-allergy-among-infants-and-children-in-turkey
#3
Aydan Kansu, Aysel Yüce, Buket Dalgıç, Bülent Enis Şekerel, Fügen Çullu-Çokuğraş, Haluk Çokuğraş
The present paper aims to provide experts' consensus on diagnosis and management of cow's milk protein allergy (CMPA) among infants and children in Turkey, based on review of available evidence-based guidelines, publications and experts' clinical experience. The experts agreed that CMPA diagnosis should be based on symptomatic evaluation and diagnostic elimination diet as followed by implementation of an open challenge test after disappearance of symptoms and confirmation of CMPA diagnosis in re-appearance of symptoms...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27920409/prevalence-of-igg-mediated-food-intolerance-among-patients-with-allergic-symptoms
#4
Zahid Shakoor, Abrar AlFaifi, Bayan AlAmro, Lama Nabil AlTawil, Rana Yazid AlOhaly
BACKGROUND: Food intolerance mediated by food specific IgG antibodies has been implicated in a variety of disorders. OBJECTIVES: To assess the prevalence of food specific IgG antibodies among patients clinically presenting with allergic symptoms lacking laboratory evidence of allergy. DESIGN: Descriptive retrospective cross-sectional study. SETTING: King Khalid University Hospital, Riyadh between 2010-2015. PATIENTS AND METHODS: Patients were screened for food specific IgG antibodies...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27920408/asthma-and-other-allergic-diseases-among-saudi-schoolchildren-in-najran-the-need-for-a-comprehensive-intervention-program
#5
Jobran M Alqahtani
BACKGROUND: In the last three decades, an increasing incidence of allergic diseases has been associated with increasing morbidity and mortality in children and young adults. OBJECTIVES: The study aimed to investigate the prevalence and risk factors associated with allergic diseases among Saudi schoolchildren in the southwestern Saudi region of Najran, and to determine the sensitization of patients to a set of allergens. DESIGN: Cross-sectional observational study...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27919315/implication-of-alternative-minimal-clinically-important-difference-threshold-estimation-methods-on-technology-assessment
#6
Diana Brixner, Eli O Meltzer, Kellie Morland, Cathryn A Carroll, Ullrich Munzel, Brian J Lipworth
OBJECTIVES: Various minimal clinically important difference (MCID) threshold estimation techniques have been applied to seasonal allergic rhinitis (SAR). The objectives of this study are to (i) assess the difference in magnitude of alternative SAR MCID threshold estimates and (ii) evaluate the impact of alternative MCID estimates on health technology assessment (HTA). METHODS: Data describing change from baseline of the reflective Total Nasal Symptom Score (rTNSS) for four intranasal SAR treatments were obtained from United States Food and Drug Administration-approved prescribing information...
December 6, 2016: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/27917623/impact-of-ige-mediated-food-allergy-on-parental-quality-of-life-in-iranian-patients
#7
Seyed Mohammad Fathi, Marzieh Tavakol, Nima Rezaei, Masoud Movahedi, Asghar Aghamohammadi, Mansoureh Shariat, Bamdad Sadeghi, Nasrin Behniafard, Behzad Darabi, Alireza Hajikhani, Ibrahim Abdollahpour, Mohammad Gharagozlou
Food allergy is a common disorder especially in the first years of life. Strict avoidance of the responsible food is the most effective therapeutic measure so far. But this continuous vigilance could be stressful for the patient and family and decreases their quality of life (QOL). This survey was designed to evaluate the impact of IgE-mediated food allergy on parental QOL in Iranian patients and to develop a valid Persian version of "Food Allergy Quality Of Life- Parental Burden (FAQL-PB) questionnaire". 90 patients (28 females, 62 males) and their parents who were referred to the clinic of Allergy in Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran were enrolled...
October 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27909880/il-9-producing-cells-in-the-development-of-ige-mediated-food-allergy
#8
REVIEW
Dana Shik, Sunil Tomar, Jee-Boong Lee, Chun-Yu Chen, Andrew Smith, Yui-Hsi Wang
Food allergy is a harmful immune reaction driven by uncontrolled type 2 immune responses. Considerable evidence demonstrates the key roles of mast cells, IgE, and TH2 cytokines in mediating food allergy. However, this evidence provides limited insight into why only some, rather than all, food allergic individuals are prone to develop life-threatening anaphylaxis. Clinical observations suggest that patients sensitized to food through the skin early in life may later develop severe food allergies. Aberrant epidermal thymic stromal lymphopoietin and interleukin (IL) 33 production and genetic predisposition can initiate an allergic immune response mediated by dendritic cells and CD4(+)TH2 cells in inflamed skin...
December 1, 2016: Seminars in Immunopathology
https://www.readbyqxmd.com/read/27905314/dutch-guideline-on-food-allergy
#9
M S van Maaren, A E J Dubois
The diagnosis of food allergy is established in cases where an immediate allergic reaction has occurred in the last year to a clearly identifiable allergenic food combined with sensitisation to this allergenic food. In all other cases, a food challenge test is required to establish or reject the diagnosis of food allergy. Although the double-blind placebo-controlled food challenge (DBPCFC) test is considered the gold standard, false-positive and false-negative outcomes occur. The incidence of false-positive outcomes is unknown because the results of DBPCFC tests cannot be further confirmed by other tests...
November 2016: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/27893940/community-healthcare-professionals-overestimate-the-risk-of-fatal-anaphylaxis-for-food-allergic-children
#10
H J Hanna, J Emmanuel, S Naim, T Umasunthar, R J Boyle
BACKGROUND: Fatal food anaphylaxis is rare, but a major concern for people with food allergy and their carers. We evaluated whether community healthcare professionals accurately estimate risk of fatal anaphylaxis for food allergic children, and whether accurate risk estimation is related to competence in recognizing and managing anaphylaxis. METHODS: We enrolled 90 community healthcare professionals in a cross-sectional survey - 30 primary care nurses, 30 school first aiders, 30 community pharmacists...
December 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27886644/oral-administration-with-diosgenin-enhances-the-induction-of-intestinal-t-helper-1-like-regulatory-t-cells-in-a-murine-model-of-food-allergy
#11
Chung-Hsiung Huang, Chia-Chi Wang, Yu-Chin Lin, Masatoshi Hori, Tong-Rong Jan
Although the development of T helper (Th)1-like regulatory T (Treg) cells under Th1 inflammatory conditions has been reported, the role of Th1-like Treg cells in Th2 allergic responses remains mostly unclear. We previously demonstrated that diosgenin, the major sapogenin contained in the Chinese yam, attenuated food allergy and augmented Th1 and Treg immune responses. In this study, we hypothesized that diosgenin may enhance the induction of Th1-like Treg cells in the gut of mice with food allergy. Ovalbumin (OVA)-sensitized BALB/c mice were gavaged daily with diosgenin and received repeatedly intragastric ovalbumin challenges to induce intestinal allergic responses...
November 23, 2016: International Immunopharmacology
https://www.readbyqxmd.com/read/27886387/coping-strategies-alexithymia-and-anxiety-in-young-patients-with-food-allergy
#12
Laura Polloni, Audrey DunnGalvin, Emilia Ferruzza, Roberta Bonaguro, Francesca Lazzarotto, Alice Toniolo, Nicolò Celegato, Antonella Muraro
BACKGROUND: Food allergy is major public health concern affecting nearly 15 million Americans and 80 million Europeans. Risk of anaphylaxis and implications for social activities affect patients' quality of life and psychological wellbeing. We previously found that young patients reported higher levels of alexithymia (difficulty in recognizing and expressing emotions) compared to healthy peers, and may influence affect, management style and clinical outcomes. This study aimed to explore links between coping strategies, alexithymia and anxiety among food-allergic adolescents and young adults...
November 25, 2016: Allergy
https://www.readbyqxmd.com/read/27883239/individually-dosed-omalizumab-an-effective-treatment-for-severe-peanut-allergy
#13
J Brandström, M Vetander, G Lilja, S G O Johansson, A-C Sundqvist, F Kalm, C Nilsson, A Nopp
BACKGROUND: Treatment with omalizumab has shown a positive effect on food allergies, but no dosages are established. Basophil allergen threshold sensitivity (CD-sens) can be used to objectively measure omalizumab treatment efficacy and correlates with the outcome of Double Blind Placebo Controlled Food Challenge to peanut. OBJECTIVE: To evaluate if individualized omalizumab treatment monitored by CD-sens could be an effective intervention for suppression of allergic reactions to peanut...
November 24, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27883236/long-term-reduction-in-food-allergy-susceptibility-in-mice-by-combining-breastfeeding-induced-tolerance-and-tgf-%C3%AE-enriched-formula-after-weaning
#14
Akila Rekima, Patricia Macchiaverni, Mathilde Turfkruyer, Sebastien Holvoet, Lénaïck Dupuis, Nour Baiz, Isabella Annesi-Maesano, Annick Mercenier, Sophie Nutten, Valérie Verhasselt
BACKGROUND: Oral tolerance induction in early life is a promising approach for food allergy prevention. Its success requires the identification of factors necessary for its persistence. OBJECTIVES: We aimed to assess in mice duration of allergy prevention by breastfeeding-induced oral tolerance and whether oral TGF-β supplementation after weaning would prolong it. METHODS: We quantified ovalbumin (OVA) and OVA specific immunoglobulins levels by ELISA in milk from the EDEN birth cohort...
November 24, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27880051/multimorbidities-of-asthma-allergies-and-airway-illnesses-in-childhood-chance-or-not-chance
#15
Wei Liu, Chen Huang, Xueying Wang, Jiao Cai, Yu Hu, Zhijun Zou, Louise B Weschler, Li Shen, Jan Sundell
OBJECTIVES: We investigated patterns of multimorbidities among asthma, allergies, and respiratory illnesses in preschool children. We examined lifetime multimorbidities of asthma, allergic rhinitis, eczema, food allergy, pneumonia, and ear infections; and current (in the last year before the survey) multimorbidities of wheeze, dry cough, rhinitis, eczema, and common cold during childhood. We further analyzed whether prevalences of these multimorbidities were due to chance. METHODS: A cross-sectional study was conducted in 72 kindergartens of Shanghai, China...
November 23, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27879501/introducing-allergenic-food-into-infants-diets-systematic-review
#16
Katelin Larson, Jessica McLaughlin, Mallory Stonehouse, Brittany Young, Kristin Haglund
PURPOSE: The purpose of this evidence-based review was to explore the association between timing of introduction of potentially allergenic foods to infants and development of food allergies. METHODS: CINAHL, Medline, PubMed, Science Direct, and Web of Science were searched using the terms solid food, complementary food, or infant feeding combined with allergy or hypersensitivity for articles published in English in 2000 or later. Inclusion criteria were 1) primary research articles with 2) a focus on association between introduction of complementary foods including potentially allergenic foods into diets of infants less than 12 months of age and development of food allergies...
November 22, 2016: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/27873335/lip-b-1-is-a-novel-allergenic-protein-isolated-from-the-booklouse-liposcelis-bostrychophila
#17
O Ishibashi, K Sakuragi, Y Fukutomi, Y Kawakami, Y Kamata, M Sakurai, S Nakayama, H Uchiyama, H Kobayashi, H Kojima, T Inui
BACKGROUND: Booklice, belonging to the order Psocoptera, are small household insect pests that are distributed worldwide. Liposcelis bostrychophila (L. bostrychophila), a common home-inhabiting species of booklouse, infests old books, sheets of paper and stored food. Recent entomological and serological studies demonstrated that L. bostrychophila accounted for the majority of detectable insects in house dust and could be a potent inducer of respiratory allergy. Our recent proteomic analysis identified a potent allergenic protein from L...
November 22, 2016: Allergy
https://www.readbyqxmd.com/read/27873194/lupin-and-other-potentially-cross-reactive-allergens-in-peanut-allergy
#18
REVIEW
Maurizio Mennini, Lamia Dahdah, Oscar Mazzina, Alessandro Fiocchi
PURPOSE OF REVIEW: The presence of IgE cross-reactivity between peanut allergens and allergens from other legumes and tree nuts has been demonstrated, but the identification of the involved individual allergens is still limited. The aim of this review is to describe new allergenic findings, of potential relevance for cross-reactivity among peanut and lupin. RECENT FINDINGS: Seventeen allergens of peanut have been included in the official allergen nomenclature database to date...
November 2016: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/27866183/resolution-of-allergic-rhinitis-and-reactive-bronchospasm-with-supplements-and-food-specific-immunoglobulin-g-elimination-a-case-report
#19
Laura Kwiatkowski, Jessica Mitchell, Jeffrey Langland
Context • Allergies are a common affliction, whether they are respiratory, food related, or dermatological. People often resort to continuous use of over-the-counter medications, such as antihistamines, to manage their symptoms. Controversy still remains over testing serum immunoglobulin (Ig) G to diagnose food allergies. Objective • This study intended to examine the benefits of treatment of a pediatric patient with natural supplements and an elimination diet for IgG food allergies. Design • The research team reported a case study...
October 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27864967/chemokine-receptors-in-allergic-diseases
#20
REVIEW
Laure Castan, Antoine Magnan, Grégory Bouchaud
Under homeostatic conditions, as well as in various diseases, leucocyte migration is a crucial issue for the immune system that is mainly organized through the activation of bone marrow-derived cells in various tissues. Immune cell trafficking is orchestrated by a family of small proteins called chemokines. Leucocytes express cell-surface receptors that bind to chemokines and trigger transendothelial migration. Most allergic diseases, such as asthma, rhinitis, food allergies and atopic dermatitis, are generally classified by the tissue rather than the type of inflammation; making the chemokine/chemokine receptor system a key point of the immune response...
November 16, 2016: Allergy
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