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https://www.readbyqxmd.com/read/28551932/-hormone-replacement-therapy-after-gynecological-malignancies
#1
REVIEW
Nadav Michaan, Dan Grisaru
Treatment of gynecological malignancies can cause an abrupt onset of menopausal symptoms along with associated long term morbidity. Hormone replacement therapy (HRT) is the most effective treatment to alleviate these symptoms but the safety of HRT among gynecologic oncology patients remains controversial. We conducted a review of the published literature on the risk of recurrent disease among gynecologic cancer patients using HRT. Our research revealed a shortage of prospective, randomized trials on this important subject...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551920/-women-s-cardiac-health-from-theory-to-activism
#2
REVIEW
Avital Porter
Cardiovascular disease (CVD) is the leading cause of death in the western world, in both genders. Although awareness of the importance of prevention, diagnosis and optimal treatment of CVD has risen in general, most women are not fully aware of their CVD risk. Moreover, women are not alert to the burden of risk in their reproductive years (e.g. complicated pregnancy and/or peri-menopausal period) and their impact on future CVD. Unique Female issues such as: fertile age, menopause, oral contraceptives, hormonal and metabolic disorders during pregnancy, labor, as well as psychological matters, and healthy life-style are major contributors to primary and secondary prevention of CVD...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28551911/-extrinsic-and-intrinsic-factors-for-falls-that-caused-hip-fracture
#3
Atzmon Tsur, Nael Shakeer, Zvi Segal, Dorit Itah, Dana Eluz
INTRODUCTION: Among the reasons described as possibly causing falls in older and elderly people are extrinsic factors such as bumping into objects, slipping on a wet floor, etc., and intrinsic factors - those that occur suddenly without warning. OBJECTIVES: To investigate the connection between the reasons for falls, extrinsic or intrinsic and different medical and nonmedical factors. METHODS: The survey included 82 people, 53 women and 29 men, who fell and broke their hip, underwent surgery, and were treated at the Rehabilitation Department...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551903/-against-all-odds-promoting-research-clinical-development-and-medical-services-of-the-conflict-in-the-galilee-medical-center
#4
Jacob Bornstein
The Galilee Medical Center (GMC) is unique in several aspects. Firstly, in the clinical aspect: In recent years, led by the Director of Medical Center, Dr. Masad Barhoum, a considerable momentum of development has taken place to reduce health discrepancies between the center and the periphery. Despite the under- financing of the health system in the Galilee, the GMC opened new clinical departments, introduced advanced medical technology and key staff members were added. This approach is depicted in publications presented in the current issue...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551891/-bisphosphonates-and-ocular-inflammation
#5
Daniel Rappoport, Hana Leiba
Bisphosphonates are a group of drugs used for treatment in several bone diseases such as osteoporosis in women, Paget's disease, hypercalcemia of malignancy, primary malignancies of the bone and metastatic bone disease (breast and prostate carcinoma). Numerous reports in the medical literature described ocular side effects in patients treated with these drugs. We report on two patients, treated with bisphosphonates due to malignancy, who presented with unilateral and bilateral uveitis. Treatment of the ocular inflammation should include local and systemic treatment and stopping the systemic use of bisphosphonates...
February 2017: Harefuah
https://www.readbyqxmd.com/read/28551878/underreporting-of-congenital-rubella-in-italy-2010-2014
#6
Cristina Giambi, Antonino Bella, Antonietta Filia, Martina Del Manso, Gloria Nacca, Silvia Declich, Maria Cristina Rota
In accordance with the goals of the World Health Organization Regional Committee for Europe, the Italian national Measles and Rubella Elimination Plan 2010-2015 aimed to reduce the incidence of congenital rubella cases to <1 case/100,000 live births by 2015. In Italy, a passive national surveillance system for congenital rubella and rubella in pregnancy is active since 2005. We estimated the degree of underreporting of congenital rubella, performing a capture-recapture analysis of cases detected through two independent sources: the national surveillance system and the national hospital discharge database, in the years 2010-2014...
May 28, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28551840/pregnancy-after-endometrial-scratching-in-infertile-couples-undergoing-ovulation-induction-and-intrauterine-insemination-cycles-a-randomized-controlled-trial
#7
Tuhina Goel, Reeta Mahey, Neerja Bhatla, Mani Kalaivani, Sangeeta Pant, Alka Kriplani
PURPOSE: To study the effect of endometrial scratching in infertile couples undergoing ovulation induction and intrauterine insemination (IUI) cycles. METHODS: A prospective randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology, AIIMS, New Delhi, India. One hundred forty-four women with primary/secondary infertility were recruited. Couples were either unexplained or male factor infertility. Subjects were randomized into intervention (scratching) and control group...
May 27, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28551774/continuous-glucose-monitoring-for-patients-with-type-1-diabetes-on-multiple-daily-injections-of-insulin-pros-and-cons
#8
Maria Ida Maiorino, Michela Petrizzo, Giuseppe Bellastella, Katherine Esposito
Continuous glucose monitoring associated with intensive insulin regimens represents a useful tool to lower HbA1c in selected adults with type 1 diabetes. Recent randomized controlled trials demonstrated greater glycemic benefits in type 1 diabetic patients treated with multiple daily injections of insulin and continuous glucose monitoring over usual care. These positive outcomes, however, are counter-balanced by several limitations that restrict the use of continuous glucose monitoring in the real life, including the apparent lack of benefits in children and pregnant diabetic women, the high cost, the stringent patients' selection, and the presence of a multi-disciplinary team with specific expertise...
May 27, 2017: Endocrine
https://www.readbyqxmd.com/read/28551770/quality-of-life-following-prophylactic-gynecological-surgery-experiences-of-female-lynch-mutation-carriers
#9
Holly Etchegary, Elizabeth Dicks, Laura Tamutis, Lesa Dawson
Lynch syndrome (LS) is a genetic condition conferring an elevated risk of gastrointestinal, gynecologic and other malignancies, often before the age of 50. Current guidelines recommend prophylactic gynecologic surgery to manage inherited cancers for female mutation carriers. Data is lacking on women's quality of life following surgery. In this pilot study, we explored how women described their quality of life post-prophylactic gynecologic surgery and the factors that affected post-surgery experiences. A qualitative interview study was the chosen design...
May 27, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28551762/prophylactic-occlusion-balloon-placement-in-internal-iliac-arteries-for-the-prevention-of-postpartum-haemorrhage-due-to-morbidly-adherent-placenta-short-term-outcomes
#10
Salvatore Alessio Angileri, Leto Mailli, Claudio Raspanti, Anna Maria Ierardi, Gianpaolo Carrafiello, Anna-Maria Belli
PURPOSE: To evaluate outcomes of uterine conserving surgery with occlusion balloon technique. A critical review of the complications was performed. MATERIALS AND METHODS: Between 2010 and 2016, pregnant women, with a prenatal diagnosis of morbidly adherent placenta (MAP), were treated with occlusion balloon catheters in both internal iliac arteries. Parameters such as need for hysterectomy, incidence of PPH, grade of MAP, estimated blood loss during delivery (EBL) and transfusion requirements, mean recovery time and duration of the balloon inflation, were collected and reviewed...
May 27, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28551760/genetic-and-environmental-influences-on-longitudinal-trajectories-of-functional-biological-age-comparisons-across-gender
#11
Deborah Finkel, Ola Sternäng, Åke Wahlin
We used an alternate age variable, functional biological age (fBioAge), which was based on performance on functional body measures. The aim was to examine development of fBioAge across the adult life span, and to also examine potential gender differences and genetic and environmental influences on change with age. We used longitudinal data (n = 740; chronological age (ChronAge) range 45-85 at baseline) from the Swedish Adoption/Twin Study of Aging. The rate of increase in fBioAge was twice as fast after ChronAge 75 than before...
May 27, 2017: Behavior Genetics
https://www.readbyqxmd.com/read/28551701/innervation-of-the-male-breast-psychological-and-physiological-consequences
#12
REVIEW
Laurent Misery, Matthieu Talagas
Breasts, including the nipple and areola, have two functions: lactation and as an erogenous area. Male breasts are much less studied that those of women. In men, breasts have only an erotic function. Because there is dense and very well organized innervation of the nipple-areola complex in men, nipple erection occurs frequently and via different mechanisms from penile erection. Although it seems to be less important for men than for women and it is poorly studied, the erotic value of breast stimulation is notable...
May 27, 2017: Journal of Mammary Gland Biology and Neoplasia
https://www.readbyqxmd.com/read/28551689/perinatal-mortality-and-morbidity-of-growth-restricted-fetuses-and-newborns-own-experience-first-report
#13
Katarzyna Pankiewicz, Tomasz Maciejewski
AIM: to evaluate the outcome of pregnancies complicated by fetal growth restriction with particular emphasis on the factors (fetal and maternal) related to perinatal mortality and morbidity of the fetus and newborn. MATERIAL AND METHODS: Retrospective analysis of the documentation of 53 women admitted with the diagnosis of fetal growth restriction based on ultrasound examination (fetal biometry and fetal vessel Doppler abnormalities). 38 (71.7%) patients were referred to our department with the diagnosis of fetal growth restriction, whereas 15 (28...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28551687/recent-highlights-of-research-on-androgen-receptors-in-women
#14
Kamil Zaręba, Iwona Sidorkiewicz
In this brief review we present an outline of the current state of research on examples of hyperandrogenism that can be strongly associated with diverse modifications in the androgen signaling pathway. We discuss the most prominent clinical features of androgen excess and correlate them with studies on androgen receptor (AR) alterations. For the first time we summarize the confirmed localizations of all known AR receptors in women. The knowledge of ARs may be the basis for AR-targeted therapies of androgenic disorders in women, including malignancy, as it has recently been demonstrated for triple-negative breast cancer...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28551675/urinary-tract-resections-in-advanced-stage-cervical-cancer-a-series-of-eight-cases
#15
Dana Nuti Oprescu, Nicolae Bacalbasa, Irina Balescu, Alexandru Filipescu
BACKGROUND/AIM: Cervical cancer is one of the most frequent malignancies in women worldwide and is unfortunately diagnosed in advanced stages of the disease. Whenever local invasion is present, neoadjuvant therapy might be needed in order to limit the degree of local invasion. However, in certain cases local invasion persists even after completing the neoadjuvant radiochemotherapy; in these patients more extensive resections might be needed in order to achieve a radical resection. PATIENTS AND METHODS: We present a case series of eight patients in whom segmental ureteral or uretero-vesical resections were performed as part of the radical resections for locally advanced cervical tumors...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28551577/bioactive-growth-hormone-in-older-men-and-women-it-s-relationship-to-immune-markers-and-healthspan
#16
William J Kraemer, Mary J Kennett, Andrea M Mastro, Roger J McCarter, Connie J Rogers, William H DuPont, Shawn D Flanagan, William J Turbitt, Maren S Fragala, Emily M Post, Wesley C Hymer
OBJECTIVE: The consequences of age-related decline in the somatotropic axis of humans are complex and remain largely unresolved. We tested the hypothesis that hGH measurements of plasma by bioassay vs immunoassay from samples obtained from free-living, elderly individuals would reveal a dichotomy in GH activities that are correlated with the functional status of the donors, i.e. their healthspan. DESIGN: Forty-one men and women of advanced age (men: N=16, age, 80...
May 8, 2017: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/28551568/a-marginal-structural-modeling-strategy-investigating-short-and-long-term-exposure-to-neighborhood-poverty-on-bmi-among-u-s-black-and-white-adults
#17
D Phuong Do, Cheng Zheng
We apply a marginal structural modeling (MSM) strategy to investigate the relationship between neighborhood poverty and BMI level among U.S. black and white adults. This strategy appropriately adjusts for factors that may be simultaneously mediators and confounders (e.g., income, health behavior), strengthening causal inference and providing the total (direct and indirect) neighborhood effect estimate. Short and long-term neighborhood poverty were positively associated with being overweight for both black and white women...
May 25, 2017: Health & Place
https://www.readbyqxmd.com/read/28551531/transcranial-direct-current-stimulation-tdcs-and-its-influence-on-analgesics-effectiveness-in-patients-suffering-from-migraine-headache
#18
Anna Przeklasa-Muszyńska, Magdalena Kocot-Kępska, Jan Dobrogowski, Maciej Wiatr, Joanna Mika
BACKGROUND: Headache is one of the most common conditions troubling nearly 45% of the world's population. Migraine headache itself, being more common among women, affects 7-18% of people. As much as 20-30% of the population report accompanying aura and neurological symptoms. In many cases, migraine headache can be effectively treated with suitably selected pharmacotherapies which include drugs used in symptomatic treatment. Frequent occurrence of the condition is treated with prophylaxis, which often fails...
March 1, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28551528/factor-structure-and-psychometric-properties-of-a-spanish-translation-of-the-body-appreciation-scale-2-bas-2
#19
Viren Swami, Antonio Alías García, David Barron
We examined the psychometric properties of a Spanish translation of the Body Appreciation Scale-2 (BAS-2) in a community sample of 411 women and 389 men in Almería, Spain. Participants completed the 10-item BAS-2 along with measures of appearance evaluation, body areas satisfaction, self-esteem, life satisfaction, and self-reported body mass index (BMI). Exploratory factor analyses with one split-half subsample revealed that BAS-2 scores had a one-dimensional factor structure in women and men. Confirmatory factor analysis with a second split-half subsample showed the one-dimensional factor structure had acceptable fit and was invariant across sex...
May 25, 2017: Body Image
https://www.readbyqxmd.com/read/28551527/placental-weight-in-the-first-pregnancy-and-risk-for-preeclampsia-in-the-second-pregnancy-a-population-based-study-of-186-859-women
#20
Johanne Dypvik, Sandra Larsen, Camilla Haavaldsen, Anne M Jukic, Lars J Vatten, Anne Eskild
OBJECTIVE: To study whether placental weight in the first pregnancy is associated with preeclampsia in the second pregnancy. STUDY DESIGN: In this population-based study, we included all women with two consecutive singleton pregnancies reported to the Medical Birth Registry of Norway during 1999-2012 (n=186 859). Placental weight in the first pregnancy was calculated as z-scores, and the distribution was divided into five groups of equal size (quintiles). We estimated crude and adjusted odds ratios with 95% confidence intervals for preeclampsia in the second pregnancy according to quintiles of placental weight z-scores in the first pregnancy...
May 17, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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