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Breast cancer and adolescent

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https://www.readbyqxmd.com/read/28865460/state-of-the-evidence-2017-an-update-on-the-connection-between-breast-cancer-and-the-environment
#1
REVIEW
Janet M Gray, Sharima Rasanayagam, Connie Engel, Jeanne Rizzo
BACKGROUND: In this review, we examine the continually expanding and increasingly compelling data linking radiation and various chemicals in our environment to the current high incidence of breast cancer. Singly and in combination, these toxicants may have contributed significantly to the increasing rates of breast cancer observed over the past several decades. Exposures early in development from gestation through adolescence and early adulthood are particularly of concern as they re-shape the program of genetic, epigenetic and physiological processes in the developing mammary system, leading to an increased risk for developing breast cancer...
September 2, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28859685/an-umbrella-review-of-the-literature-on-the-effectiveness-of-psychological-interventions-for-pain-reduction
#2
Georgios Markozannes, Eleni Aretouli, Evangelia Rintou, Elena Dragioti, Dimitrios Damigos, Evangelia Ntzani, Evangelos Evangelou, Konstantinos K Tsilidis
BACKGROUND: Psychological interventions are widely implemented for pain management and treatment, but their reported effectiveness shows considerable variation and there is elevated likelihood for bias. METHODS: We summarized the strength of evidence and extent of potential biases in the published literature of psychological interventions for pain treatment using a range of criteria, including the statistical significance of the random effects summary estimate and of the largest study of each meta-analysis, number of participants, 95% prediction intervals, between-study heterogeneity, small-study effects and excess significance bias...
August 31, 2017: BMC Psychology
https://www.readbyqxmd.com/read/28845050/preservation-of-fertility-or-ovarian-function-in-patients-with-breast-cancer-or-gynecologic-and-internal-malignancies
#3
Angrit Stachs, Steffi Hartmann, Bernd Gerber
Because of the efficacy of systemic therapies, neoplasias which occur in pediatric and adolescent patients and in young adults have high cure rates. This means that fulfilling their wish to have children has become a more pressing concern, particularly among young women with malignant tumors. Premature ovarian failure is also a not insignificant problem as it has a lasting detrimental effect on quality of life. Every oncology patient who may potentially wish to have children should be informed about their options for preserving fertility prior to starting treatment...
August 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28838083/health-impact-of-childhood-and-adolescent-soy-consumption
#4
Mark Messina, Marcelo Macedo Rogero, Mauro Fisberg, Dan Waitzberg
Soyfoods have been intensely researched, primarily because they provide such abundant amounts of isoflavones. Isoflavones are classified as both plant estrogens and selective estrogen receptor modulators. Evidence suggests that these soybean constituents are protective against a number of chronic diseases, but they are not without controversy. In fact, because soyfoods contain such large amounts of isoflavones, concerns have arisen that these foods may cause untoward effects in some individuals. There is particular interest in understanding the effects of isoflavones in young people...
July 1, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28800472/phthalate-and-bisphenol-a-exposure-during-in-utero-windows-of-susceptibility-in-relation-to-reproductive-hormones-and-pubertal-development-in-girls
#5
Deborah J Watkins, Brisa N Sánchez, Martha Maria Téllez-Rojo, Joyce M Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Karen E Peterson, John D Meeker
BACKGROUND: Over the past several decades, the age of pubertal onset in girls has shifted downward worldwide. As early pubertal onset is associated with increased risky behavior and psychological issues during adolescence and cardiometabolic disease and cancer in adulthood, this is an important public health concern. Exposure to endocrine disrupting chemicals during critical windows of in utero development may play a role in this trend. Our objective was to investigate trimester-specific phthalate and BPA exposure in relation to pubertal development among girls in the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) birth cohort...
August 8, 2017: Environmental Research
https://www.readbyqxmd.com/read/28776604/the-role-of-diet-physical-activity-body-fatness-and-breastfeeding-in-breast-cancer-in-young-women-epidemiological-evidence
#6
I Isabelle Romieu, A Amadou, V Chajes
The incidence of breast cancer (BC) is rising worldwide, with an increase in aggressive neoplasias in young women. Traditionally, BC in young women has been thought to be etiologically driven, primarily by genetic/hereditary factors. However, these factors explain only a small proportion of BCs, pointing to a role of the environment. Suspected factors responsible for this increase include lifestyle changes, notably alcohol consumption, diet with high intake of refined carbohydrates and saturated fat and low intake of polyunsaturated fatty acids (PUFA), fiber and vitamins (such as folate, vitamin D, and carotenoids), low physical activity, and body fatness, all of which may act from childhood and adolescent years through adulthood...
July 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28721554/feasibility-of-a-self-help-web-based-intervention-targeting-young-cancer-patients-with-sexual-problems-and-fertility-distress
#7
Maria Wiklander, Johanna Strandquist, Claire Micaux Obol, Lars E Eriksson, Jeanette Winterling, Kenny A Rodriguez-Wallberg, Kerstin Sjögren Fugl-Meyer, Johan Ahlgren, Per Ljungman, Claudia Lampic, Lena Wettergren
PURPOSE: The purpose of the study is to evaluate the feasibility of a self-help web-based intervention to alleviate sexual problems and fertility distress in adolescents and young adults with cancer. METHODS: Twenty-three persons with cancer (19 women and 4 men, age 18-43, 1-5 years post-diagnosis of lymphoma, breast, gynecologic, central nervous system, or testicular cancer) were recruited to test a 2-month web-based program targeting sexual problems or fertility distress...
July 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28702896/breast-cancer-risk-prediction-an-update-to-the-rosner-colditz-breast-cancer-incidence-model
#8
Megan S Rice, Shelley S Tworoger, Susan E Hankinson, Rulla M Tamimi, A Heather Eliassen, Walter C Willett, Graham Colditz, Bernard Rosner
PURPOSE: To update and expand the Rosner-Colditz breast cancer incidence model by evaluating the contributions of more recently identified risk factors as well as predicted percent mammographic density (MD) to breast cancer risk. METHODS: Using data from the Nurses' Health Study (NHS) and NHSII, we added adolescent somatotype (9 unit scale), vegetable intake (servings/day), breastfeeding (months), physical activity (MET-h/week), and predicted percent MD to the Rosner-Colditz model to determine whether these variables improved model discrimination...
July 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28702890/adiposity-during-early-adulthood-changes-in-adiposity-during-adulthood-attained-adiposity-and-mammographic-density-among-premenopausal-women
#9
Aliya Alimujiang, Catherine Appleton, Graham A Colditz, Adetunji T Toriola
PURPOSE: We investigated the associations of adolescent adiposity, changes in adiposity during adulthood, and attained adiposity with volumetric mammographic density measures. METHODS: We recruited 383 premenopausal women who had a routine screening mammogram at the Breast Health Center, Washington University in St. Louis, MO from December 2015 to October 2016. Trained research personnel assessed current adiposity measures. Weight at ages 18 and 30 were self-reported...
July 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28698185/age-at-menarche-and-late-adolescent-adiposity-associated-with-mammographic-density-on-processed-digital-mammograms-in-24-840-women
#10
Stacey E Alexeeff, Nnaemeka U Odo, Jafi A Lipson, Ninah Achacoso, Joseph H Rothstein, Martin J Yaffe, Rhea Y Liang, Luana Acton, Valerie McGuire, Alice S Whittemore, Daniel L Rubin, Weiva Sieh, Laurel A Habel
Background: High mammographic density is strongly associated with increased breast cancer risk. Some, but not all, risk factors for breast cancer are also associated with higher mammographic density.Methods: The study cohort (N = 24,840) was drawn from the Research Program in Genes, Environment and Health of Kaiser Permanente Northern California and included non-Hispanic white females ages 40 to 74 years with a full-field digital mammogram (FFDM). Percent density (PD) and dense area (DA) were measured by a radiological technologist using Cumulus...
July 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28693484/active-children-through-individual-vouchers-evaluation-active-protocol-for-a-mixed-method-randomised-control-trial-to-increase-physical-activity-levels-in-teenagers
#11
Michaela James, Danielle Christian, Samantha Scott, Charlotte Todd, Gareth Stratton, Sarah McCoubrey, Julian Halcox, Suzanne Audrey, Elizabeth Ellins, Sinead Brophy
BACKGROUND: Many teenagers are insufficiently active despite the health benefits of physical activity (PA). There is strong evidence to show that inactivity and low fitness levels increase the risk of non-communicable diseases such as coronary heart disease (CHD), type 2 diabetes and breast and colon cancers (Lee et al. Lancet 380:219-29, 2012). A major barrier facing adolescents is accessibility (e.g. cost and lack of local facilities). The ACTIVE project aims to tackle this barrier through a multi-faceted intervention, giving teenagers vouchers to spend on activities of their choice and empowering young people to improve their fitness and PA levels...
July 11, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28655118/giant-juvenile-fibroadenoma-in-a-9-year-old-a-case-presentation-and-review-of-the-current-literature
#12
Michalina Kupsik, Brian Yep, Suela Sulo, Heidi Memmel
Juvenile fibroadenoma is the most common breast mass in adolescents accounting for 0.5-4% of all cases of fibroadenomas. Giant fibroadenomas are well-circumscribed, firm breast masses characterized by proliferation of epithelial and connective tissue. They are defined as being larger than 5 cm or weighing more than 500 g. The peak age has been reported between the ages of 17 and 20, with less than 5% of these in patients less than 18-years-old.We present a 9-year-old, pre-menstrual, Nigerian female with no known family history of breast masses or cancers who developed spontaneous giant fibroadenoma measuring approximately 13  cm × 13 cm...
June 23, 2017: Breast Disease
https://www.readbyqxmd.com/read/28652281/implementation-of-a-school-based-educational-program-to-increase-breast-cancer-awareness-and-promote-intergenerational-transmission-of-knowledge-in-a-rural-mexican-community
#13
Enrique Soto-Perez-de-Celis, David D Smith, Maria Patricia Rojo-Castillo, Arti Hurria, Alba Milena Pavas-Vivas, Rina Gitler-Weingarten, Alejandro Mohar, Yanin Chavarri-Guerra
BACKGROUND: Rural women have limited access to breast cancer education, which partially contributes to late diagnosis and treatment. In this pilot study, we tested the feasibility of implementing a school-based breast cancer educational program for adolescents in a rural Mexican community. We hypothesized that the adolescents' knowledge on breast cancer would increase as a result of the program, and that there would be intergenerational transmission of that knowledge to their older female relatives...
June 26, 2017: Oncologist
https://www.readbyqxmd.com/read/28647059/-silhouettes-at-different-age-of-life-retrospective-appreciation-of-corpulence-and-his-impact-on-prevalence-of-hypertension-at-60years
#14
F Thomas, J P Empana, M A Charles, P Boutouyrie, X Jouven, B Pannier, N Danchin
PURPOSE OF THE STUDY: In epidemiological studies, recall of weight and height are not readily available at different ages of life. In order to improve the knowledge of the weight history, Sörensen et al. in 1983, developed a tool from silhouettes allowing an individual to evaluate his corpulence at different ages of life. Validity studies showed that measured weight and size were correlated to 80% in the reported silhouette. Studies have also shown that silhouettes are a good way to trace the weight history in an individual's life...
June 21, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/28602452/disease-severity-presentation-and-clinical-outcomes-among-adolescents-with-malignant-breast-neoplasms-a-20-year-population-based-outcomes-study-from-the-seer-database-1973-2009
#15
Vijayashree Murthy, Shonali Pawar, Ronald S Chamberlain
INTRODUCTION: Primary breast cancer in adolescents is extremely rare and thus is not widely studied. This study aimed to evaluate trends, characteristics, and outcomes among a cohort of adolescents with breast cancer. PATIENTS AND METHODS: A total of 657,712 female patients with breast cancer from Surveillance Epidemiology and End Results (SEER) database (1973-2009) were analyzed, and 91 adolescents were identified. Three age groups (under 20 years, 20-50 years or premenopausal, and > 50 years or postmenopausal) were compared for tumor size, stage, receptor status, and outcomes...
May 8, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28561716/breast-cancer-after-childhood-adolescent-and-young-adult-cancer-it-s-not-just-about-chest-radiation
#16
David Hodgson, Flora van Leeuwen, Andrea Ng, Lindsay Morton, Tara O Henderson
Women who have been treated for a childhood, adolescent, or young adult cancer are at an increased risk for developing breast cancer at a young age, and breast cancer accounts for the most common subsequent malignant neoplasm among female childhood and adolescent cancer survivors. Risk of breast cancer in these survivors appears to be a multifaceted relationship between constitutional factors, exposures to radiation therapy (RT) and chemotherapy, and genetic predisposition. Given the significant morbidities and mortality associated with a breast cancer diagnosis, it is imperative that health care providers understand the risks, biology and genetics, recommended surveillance guidelines for early detection, and potential prevention strategies for women who have survived pediatric and young adult cancer...
2017: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/28551081/exposure-to-stress-across-the-life-course-and-its-association-with-anxiety-and-depressive-symptoms-results-from-the-australian-women-s-wellness-after-cancer-program-wwacp
#17
Charrlotte Seib, Alexandra McCarthy, Amanda McGuire, Janine Porter-Steele, Sarah Balaam, Robert S Ware, Debra Anderson
OBJECTIVES: Earlier life stressors can increase the risk of persistent anxiety and depressive symptoms in women after cancer, though our understanding of the underlying mechanisms is limited. In this study, we tested alternative life course models to determine which best described associations between exposure to stressors in childhood, adolescence, and adulthood, and self-reported health in women previously treated for breast, gynaecological, and blood cancer. STUDY DESIGN: Data were drawn from 351 Australian women within 2 years of completing active cancer treatment who were participating in the Women's Wellness After Cancer Program (WWACP) randomised controlled trial...
May 19, 2017: Maturitas
https://www.readbyqxmd.com/read/28541571/childhood-adolescent-and-young-adult-cancer-incidence-in-japan-in-2009-2011
#18
Kota Katanoda, Akiko Shibata, Tomohiro Matsuda, Megumi Hori, Kayo Nakata, Yoshitaka Narita, Chitose Ogawa, Wataru Munakata, Akira Kawai, Hiroshi Nishimoto
Little is known about cancer incidence among children and youths in Japan. We aimed to describe cancer incidence in Japan focusing on childhood, adolescence and young adulthood (AYA). Cancer incidence data were obtained from the Monitoring of Cancer Incidence in Japan project. For the 2009-2011 incidence, the data were collected from 40 prefectures, of which data from 27 prefectures meeting quality standards were analyzed (population coverage: 38.6%). Cancers diagnosed in 0-39 years of age were classified according to the International Classification of Childhood Cancer (version 3)...
August 1, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28525533/phenol-concentrations-during-childhood-and-subsequent-measures-of-adiposity-among-young-girls
#19
Andrea L Deierlein, Mary S Wolff, Ashley Pajak, Susan M Pinney, Gayle C Windham, Maida P Galvez, Michael Rybak, Antonia M Calafat, Lawrence H Kushi, Frank M Biro, Susan L Teitelbaum
Phenolic compounds represent a class of environmental chemicals with potentially endocrine-disrupting capabilities. We investigated longitudinal associations between childhood exposure to phenols, from both manmade and natural sources, and subsequent measures of adiposity among girls enrolled in the Breast Cancer and the Environment Research Program between 2004 and 2007. Baseline (ages 6-8 years) urinary concentrations were obtained for creatinine and phenol metabolites: enterolactone, genistein, daidzein, benzophenone-3, bisphenol A, the sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichlorophenol, and triclosan...
September 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28523418/breast-cancer-and-exposure-to-tobacco-smoke-during-potential-windows-of-susceptibility
#20
Alexandra J White, Aimee A D'Aloisio, Hazel B Nichols, Lisa A DeRoo, Dale P Sandler
PURPOSE: An association between smoking and breast cancer is unresolved, although a higher risk from exposure during windows of susceptibility has been proposed. The objective of this prospective study was to evaluate the association between tobacco smoke and breast cancer with a focus on timing of exposure, especially during early life. METHODS: Sister study participants (n = 50,884) aged 35-74 were enrolled from 2003 to 2009. Women in the United States and Puerto Rico were eligible if they were breast cancer-free but had a sister with breast cancer...
July 2017: Cancer Causes & Control: CCC
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