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Ingvild Bruun Mikalsen, Øystein Karlstad, Kari Furu, Knut Øymar
BAKGRUNN: Astma kan være vanskelig å diagnostisere hos barn. For barn under skolealder finnes det få tilgjengelige objektive diagnostiske undersøkelser, og retningslinjene for diagnose og behandling er basert på sykehistorie og klinisk undersøkelse. Dette kan gi rom for varierende behandlingspraksis. KUNNSKAPSGRUNNLAG: Data fra Reseptregisteret ble brukt til å studere forskrivning av legemidler mot astma til barn i aldersgruppene 0-4 år og 5-9 år fordelt på fylker fra 2004-15...
February 19, 2018: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
Elisabeth Soegaard Christiansen, Henrik Fomsgaard Kjaer, Esben Eller, Carsten Bindslev-Jensen, Arne Høst, Charlotte Gotthard Mortz, Susanne Halken
BACKGROUND: Atopic diseases are among the most common chronic diseases in adolescents, and it is uncertain whether the prevalence of atopic diseases has reached a plateau or is still increasing. The use of the ISAAC (International Study of Asthma and Allergy in Childhood) questionnaire has provided comparable prevalence rates from many countries, whereas studies including clinical examinations and strict diagnostic criteria are scarce. We aimed to investigate the prevalence of atopic diseases, the pattern of sensitization, and comorbidities at 14 years in a prospective birth cohort...
December 2016: Pediatric Allergy and Immunology
F Bardei, H Bouziane, M Kadiri, B Rkiek, A Tebay, A Saoud
The prevalence of respiratory allergies is increasing and is a serious global health problem. The objective of the study was to determine the prevalence of skin sensitization to inhalant allergens in patients consulting for respiratory allergy, to identify the main allergens involved and to evaluate the profile of skin prick-test reactivity related to sex, age and season. This retrospective study included 379 patients consulting during 2009-2012 in three private medical offices of Tetouan. Of the 379 patients, 39...
August 2016: Revue de Pneumologie Clinique
Ai-Mei Yang, Rong Huang, Shi-Jie Jin
OBJECTIVE: To investigate ORMDL3 polymorphisms in children with asthma in Hunan, China, and to determine the relationship between ORMDL3 polymorphisms and serum osteopontin (OPN) and transforming growth factor-β1 (TGF-β1) levels. METHODS: Peripheral blood samples were collected in children with asthma (n=98; astma group) or without asthma (n=30; control group) from Hunan, China. The asthma group was subdivided into atopic (n=62) and non-atopic (n=36) subgroups...
April 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Semiha Bahceci Erdem, Hikmet Tekin Nacaroglu, Canan Sule Unsal Karkiner, Ilker Gunay, Demet Can
BACKGROUND: Leukotriene receptor antagonists (LTRAs) are drugs which have been widely used more than ten years. As the use of LTRAs increases, our knowledge with respect to their side effects increases as well. OBJECTIVES: The objective of our study was to evaluat the observed side effects of LTRAs used in patients with astma. PATIENTS AND METHODS: 1024 patients treated only with LTRAs owing to asthma or early wheezing were included in the study for a five-year period...
October 2015: Iranian Journal of Pediatrics
Kavita Ghosal, Naren Pandey, Swati Gupta Bhattacharya
INTRODUCTION AND OBJECTIVES: Pollen grains released by plants are dispersed into the air and can become trapped in human nasal mucosa, causing immediate release of allergens triggering severe Type 1 hypersensitivity reactions in susceptible allergic patients. Recent epidemiologic data show that 11-12% of people suffer from this type of disorders in India. Hence, it is important to examine whether pollen grains have a role in dissipating respiratory problems, including allergy and astma, in a subtropical suburban city...
2015: Annals of Agricultural and Environmental Medicine: AAEM
Ingvild Bruun Mikalsen, Liliane Skeiseid, Line Merete Tveit, David Hugo Engelsvold, Knut Øymar
BACKGROUND: The prevalence of childhood asthma has increased, although the rate of hospitalization for asthma seems to decrease. In Norway, the rate of hospital admission for childhood asthma from 1984 to 2000 increased. The aim of this study was to assess further trends in hospital admissions for childhood asthma up to 2010. METHODS: A population-based study including children 1-13 yrs of age hospitalized for asthma during six periods from 1984/1985 to 2009/2010 in Rogaland, Norway, was performed...
December 2015: Pediatric Allergy and Immunology
Füsun Yıldız, Gülbin Bingöl Karakoç, Refika Ersu Hamutçu, Nazan Yardım, Banu Ekıncı, Arzu Yorgancıoğlu
INTRODUCTION: Although chronic respiratory disorders are important causes of morbidity and mortality, health care workers, patients and caretakers are not well informed about these disorders. Therefore these problems are underdiagnosed and undertreated; also preventive measures are not widely taken. Our aim was to evaluate the knowledge of asthma and chronic obstructive pulmonary disease (COPD) in Turkey. This study was designed and performed as a Global Alliance Against Respiratory Disorders (GARD) project...
2013: Tüberküloz Ve Toraks
Douglas C Cowan, Jan O Cowan, Rochelle Palmay, Avis Williamson, D Robin Taylor
BACKGROUND: Statins have anti-inflammatory actions which in theory are potentially beneficial in asthma. Small trials have failed to show a significant benefit, but a systematic study to evaluate the steroid-sparing effect of statin treatment has not been carried out. METHODS: A randomised, placebo-controlled, crossover trial was conducted of simvastatin 40 mg at night with simultaneous stepwise reduction of fluticasone propionate dose until loss of control occurred, followed by an increase until regain of control ('minimum' dose required) in 51 patients with asthma and sputum eosinophils (steroid-free) ≥ 2%...
October 2010: Thorax
Helen Kopnina
INTRODUCTION: There are few studies pertaining to asthma patients' views on complementary and alternative medicine (CAM). The driving question behind the study is why some asthma patients choose noncompliance to conventional western medicine and resort to other modalities, often deemed as being 'alternative,' 'complementary,' or 'integrated.' Does the patients' emancipation movement lead to greater awareness of the benefits of alternative medicine? Does the patients' identity as asthma sufferers play a role in their decision? METHOD: Case studies based on semistructured interviews were conducted between June 2009 and January 2010 with 19 asthma patients in The Netherlands who have chosen complementary and alternative medicine (CAM)...
August 2010: Journal of Asthma: Official Journal of the Association for the Care of Asthma
Janusz Ciółkowski, Barbara Stasiowska, Henryk Mazurek
UNLABELLED: After the GINA 2006 publication, asthma therapy is based on control of symptoms. However there are suggestions of monitoring of airway inflammation. Aim of the study was to compare clinical criteria of asthma control with cellular markers of lower airway inflammation in induced sputum in a group of young asthmatics. To assess relationship between sputum eosinophilia, asthma severity and spirometry. MATERIAL AND METHODS: A group of 154 young patients with chronic asthma (8-21 years) underwent sputum induction by inhalation of 4,5% saline solution...
March 2009: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Pernille Christensen, Simon Francis Thomsen, Niels Rasmussen, Vibeke Backer
Recent studies suggest that exercise-induced inspiratory stridor (EIIS) is an important and often overlooked differential diagnosis of exercise-induced asthma. EIIS is characterised by astma-like symptoms, but differs by inspiratory limitation, fast recovery, and a lack of effect of inhaled bronchodilators. The prevalence of EIIS is reported to be 5-27%, and affects both children and adults. The pathophysiology, the pathogenesis, and the treatment of the condition are not yet clarified. At present, a population-based study is being conducted in order to address these points...
November 19, 2007: Ugeskrift for Laeger
Ingibjœrg Georgsdóttir, Evald Sæmundsen, Ingibjœrg Símonardóttir, Jónas G Halldórsson, Snæfríður Thorn Egilson, Thornóra Leósdóttir, Brynhildur Ingvarsdóttir, Einar Sindrason, Atli Dagbjartsson
OBJECTIVE: Survival of extremely low birthweight infants (BW<1000g) in Iceland has increased in recent years, especially since the availability of surfactant therapy for Respiratory Distress Syndrome of Prematurity. This study was part of a geographically defined national study on survival, health, development and longterm outcome of extremely low birthweight (ELBW) infants in Iceland focusing on health, development and disabilities with reference to a control group. MATERIAL AND METHODS: Information from the National Birth Registry on births in Iceland of ELBW infants weighing 500-999g was collected in two periods 1982-90 and 1991-95, before and after surfactant therapy became available...
July 2003: Læknablađiđ
B J Vlieg-Boerstra, S van der Heide, C M A Bijleveld, J Kukler, E J Duiverman, S A A Wolt-Plompen, A E J Dubois
OBJECTIVE: The purpose of this investigation was to verify if avoidance of allergenic foods in children adhering to a food allergen avoidance diet from birth was complete and feasible, and whether dietary assessment can be used as a tool in predicting the outcome of double-blind, placebo-controlled food challenges (DBPCFCs). DESIGN: Children adhering to an allergen avoidance diet from birth underwent DBPCFCs. The investigator-dietician verified whether the elimination was complete, using food frequency questionnaires for common allergenic foods...
December 2006: European Journal of Clinical Nutrition
R Meerwaldt, R J Odink, R Landaeta, F Aarts, B Brunekreef, J Gerritsen, W M C Van Aalderen, M O Hoekstra
BACKGROUND: The Th1/Th 2 concept is a model to understand the pathophysiology of certain diseases. Atopic diseases (asthma, eczema and hayfever) are characterized by a chronic inflammatory reaction that is dominated by Th 2 cells, and type 1 diabetes mellitus (DM) is Th1 cell dominated. Because it is known that Th1 and Th 2 cells reciprocally counteract each other, it can be speculated that the prevalence of Th 2-mediated disease is lower in patients with Th1-mediated disease. OBJECTIVE: To compare the prevalence of atopic diseases between children with DM and age-matched controls...
February 2002: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
T M Zinchenko
A total of 103 women were examined with bronchial asthma, who demonstrated disturbances in the intrapsychic adaptation presenting as hystero-hypochondriacal and anxious alterations in the personality pattern with formation of a certain modus of thinking and behavior. Differences have been ascertained in the personality profile of patients with varying clinicopathogenetic forms of bronchial astma in those groups of patients differing in age, degree of severity of the condition duration of the analysis.
July 2001: Likars'ka Sprava
S Pedersen
No abstract text is available yet for this article.
1997: Ugeskrift for Laeger
H Mikkelsen, J C Larsen, F Tarding
It is well known that synthetic food colours especially some azo dyes can provoke hypersensitivity reactions such as urticaria, angioneurotic oedema, and astma (Michaëlsson and Juhlin, 1973, Granholt and Thune, 1975). Natural food colours are scarcely investigated with respect to potential allergic properties. Annatto extract, a commonly used food colour in edible fats e.g. butter, has been tested in patients. Among 61 consecutive patients suffereing from chornic urticaria and/or angioneurotic oedema 56 patients were orally provoked by annatto extract during elimination diet...
1978: Archives of Toxicology. Supplement., Archiv Für Toxikologie. Supplement
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