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https://www.readbyqxmd.com/read/29773124/otolaryngology-and-the-global-burden-of-disease
#1
REVIEW
James E Saunders, Zane Rankin, Kathryn Y Noonan
The Global Burden of Disease (GBD) project provides longitudinal analysis of the global burden of otolaryngologic diseases by measuring the all-cause mortality, years of life lost, the years of life lived with disability, and disability-adjusted life years. Hearing loss burden is assessed overall and as sequelae of other diseases, such as otitis media or meningitis. Using these measures, we can appreciate the high prevalence and disability related to hearing loss globally. Other otolaryngologic diseases that contribute to the GBD include otitis media, cleft lip and palate, head and neck cancer, facial trauma, and oral disorders...
June 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29771829/repairing-a-facial-cleft-by-polyether-ether-ketone-implant-combined-with-titanium-mesh
#2
Yuan Deng, Weiwei Tang, Zhengkang Li
The Tessier Number 4 cleft is one of the rarest, most complex craniofacial anomalies that presents difficulties in surgical treatment. In this article, we report a case of simultaneous facial depression, eye displacement, and medial canthus deformity. In this case, the maxillary bony defect was reconstructed using computer-assisted design computer-assisted manufacturing (CAD-CAM) polyether-ether-ketone (PEEK) material, and the orbital floor defect was repaired with AO prefabricated titanium mesh. Additionally, the medial canthus was modified with canthopexy and a single Z-plasty flap...
May 15, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29758316/double-limbal-dermoid-with-tessier-s-paramedian-facial-cleft
#3
Nirupama Kasturi, Jayashree Rajkumar
No abstract text is available yet for this article.
May 11, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29752048/assessment-of-regional-asymmetry-of-the-face-before-and-after-surgical-correction-of-unilateral-cleft-lip
#4
Dhelal Al-Rudainy, Xiangyang Ju, Steve Stanton, Felicity V Mehendale, Ashraf Ayoub
This study was carried out on 26 unilateral cleft lip and palate (UCLP) cases with mean age 3.6 ± 0.7 months.3D facial images were captured for each infant 2-3 days before the repair of cleft lip and at 4 months following surgery at a mean age of 8.2 ± 1.8 months, using a stereophotogrammetry imaging system. An iterative closest point (ICP) algorithm was used to superimpose the 3D facial model to its mirror image using VRMesh software. After the superimposition, the face model was divided into seven anatomical regions...
April 6, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29745448/early-development-of-the-human-dentition-revisited
#5
REVIEW
Maria Hovorakova, Herve Lesot, Miroslav Peterka, Renata Peterkova
In this review, classical data on the early steps in human odontogenesis are summarized and updated with specific insights into the development of the upper and lower embryonic jaws to help in understanding some oral pathologies. The initial step of human odontogenesis is classically characterized by two parallel horseshoe-shaped epithelial laminae. These originate from the oral epithelium and an ingrowth into the jaw mesenchyme: the internal dental lamina gives rise to deciduous tooth primordia, while the external vestibular lamina represents the developmental base of the oral vestibule...
May 10, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29744331/anatomical-repair-of-a-bilateral-tessier-no-3-cleft-by-midfacial-advancement
#6
Ji-Hyeon Oh, Young-Wook Park
Background: Bilateral Tessier number 3 clefts are extremely rare, and their surgical treatments have not been well established. Case presentation: The authors describe the case of a patient with a right Tessier number 3, 11 facial cleft with microphthalmia, a left Tessier number 3 facial cleft with anophthalmia, and cleft palate. We repaired simultaneously the bilateral soft tissue clefts by premaxillary repositioning, cleft lip repair, facial cleft repair by nasal lengthening, midfacial advancement, and an upper eyelid transposition flap with repositioning both the medial canthi...
December 2018: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29742362/assessing-attentional-bias-in-secondary-cleft-lip-deformities-an-eye-tracking-study
#7
Alexander Morzycki, Alison Wong, Paul Hong, Michael Bezuhly
OBJECTIVE: Using a well-established measure of attention, we aimed to objectively identify differences in severity between types of simulated secondary cleft lip deformities. DESIGN: Volunteer participants viewed a series of images of a child digitally modified to simulate different secondary unilateral cleft lip deformities (long lip, short lip, white roll/vermilion disjunction, and vermilion excess), a lip scar with no secondary deformity, or a normal lip. Eye movements were recorded using a table-mounted eye-tracking device...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29724746/a-descriptive-study-of-chlorhexidine-as-a-disinfectant-in-cleft-palate-surgery
#8
Gieljam Johannes Roode, Kurt-Wilhelm Bütow
OBJECTIVES: Chlorhexidine is seen as the golden standard of disinfectants. It is widely used to clean surgical sites. Many articles indicate resistance of pathogens to chlorhexidine. One study indicated that pathogenic micro-organisms were isolated from the soft palate cleft region in 57% of patients with facial clefts. The objective was to determine if chlorhexidine application is effective in removing pathogens from the surgical site in these patients. Secondly, if any pathogens were isolated, are they resistant to any other antimicrobials...
May 3, 2018: Clinical Medicine & Research
https://www.readbyqxmd.com/read/29720198/translation-and-validation-of-the-french-version-of-the-child-perceptions-questionnaire-for-children-aged-from-8-to-10-years-old-cpq-8-10
#9
Marie-Laure Boy-Lefèvre, Noéline Razanamihaja, Sylvie Azogui-Lévy, Andréa Vigneron, Laurence Jordan, Ariane Berdal, Muriel de la Dure-Molla
BACKGROUND: The Child Perceptions Questionnaire (CPQ) belongs to a set of questionnaires measuring Child Oral Health Quality of Life (COHQOL). The CPQ is used to collect the perceptions of children on the impact of oral diseases on their quality of life. This cross-sectional study was aimed to translate the CPQ8-10 into French language and evaluate its psychometric properties. METHODS: The translation process complied with international recommendations. The final French version was tested on children aged 8-10 years old attending consultations in a Parisian public hospital and divided into three groups: children with oral-facial clefts, children with dental anomalies linked to a rare disease other than clefts and children presumed to be healthy and without anomalies...
May 3, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29719267/high-resolution-epigenomic-atlas-of-human-embryonic-craniofacial-development
#10
Andrea Wilderman, Jennifer VanOudenhove, Jeffrey Kron, James P Noonan, Justin Cotney
Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within intronic sequences. However, systematic identification of regulatory sequences important for forming the human face has not been performed. Here, we describe comprehensive epigenomic annotations from human embryonic craniofacial tissues and systematic comparisons with multiple tissues and cell types...
May 1, 2018: Cell Reports
https://www.readbyqxmd.com/read/29709332/surgical-indication-of-furlow-palatoplasty-to-treat-submucous-cleft-palate
#11
Joon Hyun Kwon, Jeong Woo Lee, Jung Dug Yang, Ho Yun Chung, Byung Chae Cho, Kang Young Choi
This study investigated the effects of Furlow palatoplasty on children with submucous cleft palate (SMCP) and identified surgical indications by comparing SMCP and control patients. Twenty-three SMCP children (average age 28.9 months) who were nonsyndromic and underwent surgery between April 2010 and December 2016 were included. Facial computed tomography (CT) was performed preoperatively and at least 1 year postoperatively after a language test. Facial CT measurements were taken for 140 children aged 0-6 years without deformities (control group)...
March 29, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29708800/birth-prevalence-of-orofacial-clefts-in-kuwait-from-hospital-based-registration-retrospective-study
#12
Wasmiya A Alhayyan, Sharat C Pan, Fawzi M AlQatami
INTRODUCTION: Cleft lip and palate (CLAP) are the most common craniofacial anomalies and birth defects globally. Despite the fact that a tertiary care registry of clefts has existed in Kuwait since 2008, to date there is no published data regarding the prevalence of orofacial clefts in this population. OBJECTIVE: To tabulate the pattern of orofacial clefts from tertiary care center registration during 2009 through 2014 and to estimate the prevalence and trend using population-based records...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29707466/quantifying-soft-tissue-shape-and-symmetry-patients-with-cleft-lip-palate-and-facial-paralysis
#13
Carroll Ann Trotman, Julian Faraway, Tessa Hadlock, Caroline Banks, Nathan Jowett, Daniel Regan
Background: The objective of this study was to demonstrate simple three-dimensional analyses of facial soft tissue shape and asymmetry. Methods: There were 2 study samples: one retrospective comprised patients with repaired cleft lip and palate (CL/P) and control subjects; and the other prospective comprised patients with unilateral facial paralysis (FP) and control subjects. The data collected were digitized three-dimensional facial landmarks. Scores for shape and asymmetry of subjects' faces and for different facial regions were generated using Procrustes methods...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29707444/applications-of-computer-technology-in-complex-craniofacial-reconstruction
#14
Kristopher M Day, Kyle S Gabrick, Larry A Sargent
Background: To demonstrate our use of advanced 3-dimensional (3D) computer technology in the analysis, virtual surgical planning (VSP), 3D modeling (3DM), and treatment of complex congenital and acquired craniofacial deformities. Methods: We present a series of craniofacial defects treated at a tertiary craniofacial referral center utilizing state-of-the-art 3D computer technology. All patients treated at our center using computer-assisted VSP, prefabricated custom-designed 3DMs, and/or 3D printed custom implants (3DPCI) in the reconstruction of craniofacial defects were included in this analysis...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29679588/growth-and-development-of-craniofacial-structures-in-patients-at-different-ages-with-unrepaired-submucous-cleft-palate
#15
Congcong Cao, Xue Xu, Qian Zheng, Bing Shi, Jingtao Li, Yan Wang
PURPOSE: Submucous cleft palate (SMCP) is a particular subtype of cleft palate deformity; research related to the craniofacial features of patients with SMCP is comparatively rare. The study objective was to perform a cephalometric comparison of the craniofacial features of patients with SMCP and non-cleft controls at different ages. MATERIALS AND METHODS: The sample in this cross-sectional study was composed of 2 groups: SMCP patients and non-cleft controls. The primary predictor variables were study group (cleft and non-cleft) and age...
March 28, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29671724/facial-disfigurement-and-identity-a-review-of-the-literature-and-implications-for-facial-transplantation
#16
William J Rifkin, Rami S Kantar, Safi Ali-Khan, Natalie M Plana, J Rodrigo Diaz-Siso, Manos Tsakiris, Eduardo D Rodriguez
Facial disfigurement can significantly affect personal identity and access to social roles. Although conventional reconstruction can have positive effects with respect to identity, these procedures are often inadequate for more severe facial defects. In these cases, facial transplantation (FT) offers patients a viable reconstructive option. However, FT's effect on personal identity has been less well examined, and ethical questions remain regarding the psychosocial ramifications of the procedure. This article reviews the literature on the different roles of the face as well as psychological and social effects of facial disfigurement...
April 1, 2018: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29665341/the-median-mandibular-symphysis-tessier-30-cleft-3d-imaging-analysis-and-review-of-the-literature
#17
Siddharth Mahajan, Pravin K Patel, Yao Duan, Neil Warshawsky
Atypical craniofacial clefts of the upper facial region have been well documented; however, the mandibular clefts remain rare and reported as isolated case reports. We report a case of a median mandibular cleft within the context of a Tessier 0-14 axis that we have followed over a 5-year period without surgical/orthodontic intervention. The mandibular symphysis cleft remained open without evidence of the fusion, in contrast to ossification of the metopic dysraphism. Within this context, we present a review of the median mandibular cleft cases from 1819 to 2015...
May 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29663709/soft-tissue-nasal-asymmetry-as-an-indicator-of-orofacial-cleft-predisposition
#18
Charles Zhang, Steven F Miller, Jasmien Roosenboom, George L Wehby, Lina M Moreno Uribe, Jacqueline T Hecht, Frederic W B Deleyiannis, Kaare Christensen, Mary L Marazita, Seth M Weinberg
The biological relatives of offspring with nonsyndromic orofacial clefts have been shown to exhibit distinctive facial features, including excess asymmetry, which are hypothesized to indicate the presence of genetic risk factors. The significance of excess soft tissue nasal asymmetry in at-risk relatives is unclear and was examined in the present study. Our sample included 164 unaffected parents from families with a history of orofacial clefting and 243 adult controls. Geometric morphometric methods were used to analyze the coordinates of 15 nasal landmarks collected from three-dimensional facial surface images...
April 16, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29661814/psychometric-findings-and-normative-values-for-the-cleft-q-based-on-2434-children-and-young-adult-patients-with-cleft-lip-and-or-palate-from-12-countries
#19
Anne F Klassen, Karen Wy Wong Riff, Natasha M Longmire, Asteria Albert, Gregory C Allen, Mustafa Asim Aydin, Stephen B Baker, Stefan J Cano, Andrew J Chan, Douglas J Courtemanche, Marieke M Dreise, Jesse A Goldstein, Timothy E E Goodacre, Karen E Harman, Montserrat Munill, Aisling O Mahony, Mirta Palomares Aguilera, Petra Peterson, Andrea L Pusic, Rona Slator, Mia Stiernman, Elena Tsangaris, Sunil S Tholpady, Federico Vargas, Christopher R Forrest
BACKGROUND: Patients with cleft lip and/or palate can undergo numerous procedures to improve appearance, speech, dentition and hearing. We developed a cleft-specific patient-reported outcome instrument to facilitate rigorous international measurement and benchmarking. METHODS: Data were collected from patients aged 8-29 years with cleft lip and/or palate at 30 hospitals in 12 countries between October 2014 and November 2016. Rasch measurement theory analysis was used to refine the scales and to examine reliability and validity...
April 16, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29652578/mr-imaging-of-the-fetal-face-comprehensive-review
#20
Murali Nagarajan, Kedar G Sharbidre, Sudeep H Bhabad, Sharon E Byrd
The human face is a complex anatomic structure with an equally complex embryologic development. Derangement of the developmental process can result in various structural anomalies, which range from a mainly cosmetic deformity, such as cleft lip, to potentially life-threatening conditions such as arhinia. These anomalies (a) can occur as isolated anomalies; (b) can be associated with intracranial, spinal, or dental anomalies; or (c) can be a part of various syndromes, thus serving as diagnostic clues in such cases...
April 13, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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