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Coronary artery bypass

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https://www.readbyqxmd.com/read/29040496/changes-in-platelet-bax-levels-contribute-to-impaired-platelet-response-to-thrombin-after-cardiopulmonary-bypass-prospective-observational-clinical-and-laboratory-investigations
#1
M Murase, Y Nakayama, D I Sessler, N Mukai, S Ogawa, Y Nakajima
Background: Anucleate platelets can undergo apoptosis in response to various stimuli, as do nucleated cells. Cardiopulmonary bypass (CPB) causes platelet dysfunction and can also activate platelet apoptotic pathways. We therefore evaluated time-dependent changes in blood platelet Bax (a pro-apoptotic molecule) levels and platelet dysfunction after cardiac surgery. Methods: We assessed blood samples obtained from subjects having on-pump or off-pump coronary artery bypass graft surgery (n=20 each)...
October 10, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29036976/-comparison-of-perioperative-serum-thrombomodulin-levels-in-patients-underwent-off-pump-coronary-artery-bypass-grafting-with-and-without-cardiogenic-shock
#2
L Zhang, C Wang, T X Gu, C M Lu, Z W Wang
Objective: To observe the perioperative changes of serum thrombomodulin in patients with and without cardiogenic shock undergoing off-pump coronary artery bypass grafting surgery. Methods: A total of 66 patients with coronary artery disease who underwent off-pump coronary artery bypass grafting surgery between June and December 2015 in our hospital were included in this study.The patients were divided into non-cardiogenic shock group (n=51) and shock group (n=15) according to the absence or presence of cardiogenic shock...
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29035780/long-non-coding-rnas-in-the-atherosclerotic-plaque
#3
Serdal Arslan, Öcal Berkan, Torkia Lalem, Nil Özbilüm, Sabahattin Göksel, Özge Korkmaz, Nilgün Çetin, Yvan Devaux
BACKGROUND AND AIMS: Genetic and environmental factors are important components of the development of atherosclerosis. Long non-coding RNA (lncRNAs) have emerged as regulators of multiple pathophysiological pathways in the cardiovascular system. Here, we investigated potential associations between lncRNAs and atherosclerosis. METHODS: Tissue samples from atherosclerotic coronary artery plaques and non-atherosclerotic internal mammary artery were obtained from 20 patients during coronary artery bypass surgery...
October 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29034751/less-than-two-versus-greater-than-two-hour-invasive-strategy-in-non-st-elevation-myocardial-infarction-a-meta-analysis-of-randomized-controlled-trials
#4
Poonam Velagapudi, Mohit Turagam, Dhaval Kholte, Sahil Khera, Parag Parikh, Omar Hyder, Herbert Aronow, Dawn Abbott
BACKGROUND: Optimal timing for an invasive strategy in non-ST elevation myocardial infarction (NSTEMI) is unclear. Whether clinical outcomes are improved with a less than two (LT2) compared with greater than two hour (GT2) invasive strategy remains to be determined. We performed a meta-analysis of randomized controlled trials (RCTs) comparing LT2 vs GT2 for NSTEMI. METHODS: A comprehensive literature search for RCTs comparing LT2 vs. GT2 in NSTEMI patients was performed...
October 16, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29034031/coronary-artery-bypass-surgery-in-end-stage-renal-disease-patients
#5
REVIEW
Daijiro Hori, Atsushi Yamaguchi, Hideo Adachi
The number of patients requiring hemodialysis is continuously increasing around the world. Hemodialysis affects patient quality of life and it is also associated with a higher risk for cardiovascular events. In addition to traditional risk factors for cardiovascular events such as hypertension, hyperlipidemia, and diabetes, hemodialysis is associated with hyperphosphatemia, chronic inflammation, vascular calcification, and anemia which accelerate atherosclerosis, vascular stiffness, and cardiac ischemia. Treatment strategy for coronary revascularization in this progressive disease remains controversial...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033836/delivery-of-antioxidant-and-anti-inflammatory-agents-for-tissue-engineered-vascular-grafts
#6
REVIEW
Kenyatta S Washington, Chris A Bashur
The treatment of patients with severe coronary and peripheral artery disease represents a significant clinical need, especially for those patients that require a bypass graft and do not have viable veins for autologous grafting. Tissue engineering is being investigated to generate an alternative graft. While tissue engineering requires surgical intervention, the release of pharmacological agents is also an important part of many tissue engineering strategies. Delivery of these agents offers the potential to overcome the major concerns for graft patency and viability...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29032613/management-of-ventricular-perforation-during-revascularization-of-an-intramyocardial-left-anterior-descending-artery
#7
Chinwe Nwokocha, Ghannam A Al-Dossari, Vincent R Conti, Abe DeAnda, Patrick T Roughneen
Ventricular perforation during exposure of an intramyocardial left anterior descending artery (LAD) in preparation for coronary artery bypass grafting is a known surgical complication. In this report, we discuss the management of this complication which avoids closure of the LAD and a myocardial infarction.
October 15, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29031174/dynamic-right-ventricular-outflow-obstruction-a-rare-cause-of-hypotension-during-anestesia-induction
#8
Maria Enrica Antoniucci, Christian Colizzi, Gabriella Arlotta, Maria Calabrese, Michele Corrado, Sergio Guarneri, Lorenzo Martinelli, Andrea Scapigliati, Roberto Zamparelli, Franco Cavaliere
INTRODUCTION: Dynamic obstruction of right ventricle outflow tract (RVOTO) is a rare condition that may acutely cause severe heart failure. It has been reported in some hypertrophic cardiomyopathies, after lung transplantation, and in some cases of hemodynamic instability after cardiopulmonary bypass. PRESENTATION OF CASE: We report the case of a 71-year-old man who developed severe hypotension during the induction of general anesthesia for surgical coronary revascularization...
October 5, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29029526/percutaneous-coronary-intervention-using-drug-eluting-stents-versus-coronary-artery-bypass-graft-surgery-in-left-main-coronary-artery-disease-an-updated-meta-analysis-of-randomized-clinical-trials
#9
Lei Gao, Yuqi Liu, Zhijun Sun, Yabin Wang, Feng Cao, Yundai Chen
OBJECTIVES: To compare the safety and efficacy of percutaneous coronary intervention (PCI) using drug-eluting stent (DES) and coronary artery bypass graft (CABG) for the treatment of left main coronary artery (LMCA) disease. BACKGROUND: Several new randomized trials have recently examined the clinical outcomes of PCI and CABG in LMCA disease. However, the results of these studies were inconsistent. MATERIALS AND METHODS: We searched five online electronic databases to identify all the randomized clinical trials assessing the outcomes of PCI using DES and CABG in patients with LMCA...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29029034/ten-year-experience-of-endocardial-linear-infarct-exclusion-technique-for-ischaemic-cardiomyopathy
#10
Suguru Ohira, Sachiko Yamazaki, Satoshi Numata, Hidetake Kawajiri, Kazuki Morimto, Kiyoshi Doi, Hitoshi Yaku
OBJECTIVES: To report the mid-term results of our surgical ventricular restoration procedure, called the endocardial linear infarct exclusion technique (ELIET), for ischaemic cardiomyopathy. METHODS: From 2006 to 2015, 43 consecutive patients who underwent surgical ventricular restoration with ELIET for ischaemic cardiomyopathy were retrospectively analysed. RESULTS: The mean age of patients at surgery was 65.3 ± 9.2 years and EuroSCORE II was 13...
September 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029030/outcomes-of-surgery-for-infective-endocarditis-a-single-centre-experience-of-801-patients
#11
Sameh M Said, Zaid M Abdelsattar, Hartzell V Schaff, Kevin L Greason, Richard C Daly, Alberto Pochettino, Lyle D Joyce, Joseph A Dearani
OBJECTIVES: Infective endocarditis (IE) remains a life-threatening disease, despite the improvement in diagnostic and therapeutic measures. We reviewed our outcomes for all adults who underwent surgery for endocarditis at our centre. METHODS: Between January 1995 and December 2013, 801 patients [586 men (73%)] underwent surgery for IE. Mean age was 60 ± 14.7 years. Native endocarditis (NE) was present in 372 patients (46%), and 379 (47%) patients had active IE...
October 3, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029008/complete-arterial-revascularization-using-bilateral-internal-mammary-artery-in-t-graft-technique-for-multivessel-coronary-artery-disease-in-on-or-off-pump-approach-does-gender-lose-its-historical-impact-on-clinical-outcome
#12
Friedrich-Christian Rieß, Christian-Alexander Behrendt, Wagma Amin, Stefan Heller, Lorenz Hansen, Stephan Winkel, Jan Stripling, Henrik Christian Rieß
OBJECTIVES: Higher rates of mortality and morbidity have been reported in women undergoing coronary artery bypass grafting (CABG) compared with men. Different revascularization techniques (on-pump and off-pump) might influence this outcome. METHODS: We retrospectively analysed 3445 consecutively recruited patients (all comers) undergoing complete arterial CABG (CACABG) at a single centre between January 2000 and December 2012. CACABG was performed in all patients using bilateral skeletonized internal mammary artery in T-graft technique, either on-pump (n = 2216) or off-pump (n = 1229)...
September 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29028651/endoscopic-conduit-harvest-in-coronary-artery-bypass-grafting-surgery-an-ismics-systematic-review-and-consensus-conference-statements
#13
Francis D Ferdinand, John K MacDonald, Husam H Balkhy, Gianluigi Bisleri, Ho Young Hwang, Patricia Northrup, Richard H J Trimlett, Lai Wei, Bob B Kiaii
OBJECTIVE: The purpose of this consensus conference was to develop and update evidence-informed consensus statements and recommendations on harvesting saphenous vein and radial artery via an open as compared with endoscopic technique by systematically reviewing and performing a meta-analysis of randomized and nonrandomized clinical trials. METHODS: All randomized controlled trials and nonrandomized controlled trials included in the first the International Society for Minimally Invasive Cardiothoracic Surgery Consensus Conference and Statements, in 2005 up to November 30, 2015, were included in a systematic review and meta-analysis...
October 13, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29027271/surgical-treatment-of-coronary-artery-aneurysms
#14
Erik Beckmann, Saad Rustum, Steffen Marquardt, Constanze Merz, Malakh Shrestha, Andreas Martens, Axel Haverich, Issam Ismail
INTRODUCTION: Coronary artery aneurysms (CAA) are rare. We present our experience with the surgical treatment of patients with CAAs. METHODS: Between March 2000 and October 2016, 15 patients with CAA underwent surgery. RESULTS: Mean age of patients was 60 ± 16 years and 47% (n = 7) were male. Kawasaki syndrome was present in two (13%) patients and 7% (n = 1) patients had Marfan syndrome. Isolated CAAs were found in 73% (n = 11) and involvement of multiple vessels was present in 27% (n = 4) of patients...
October 13, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29027034/low-intensity-led-therapy-%C3%AE-640%C3%A2-%C3%A2-%C3%A2-20%C3%A2-nm-on-saphenectomy-healing-in-patients-who-underwent-coronary-artery-bypass-graft-a-randomized-double-blind-study
#15
Raimundo de Barros Araújo Júnior, Isabel Clarisse Albuquerque Gonzaga, Gilderlene Alves Fernandes, Andréa Conceição Gomes Lima, Paulo Sergio Tajra Cortelazzi, Rauirys Alencar de Oliveira, Renata Amadei Nicolau
Myocardial revascularization surgery (CABG) is the most appropriate treatment for coronary artery disease. Currently, the great challenge is to reduce postoperative complications, such as wound infections, dehiscence, pain, and patients' quality of life. The saphenectomy is the target of complications in 10% of cases, which can cause greater morbidity, time, and cost of hospitalization. Studies show that low-intensity laser or light-emitted diode (LED) therapy promotes positive biomodulation of the tissue repair process, culminating in a lower incidence of dehiscence, pain reduction, and improvement in quality of life...
October 13, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29026892/prompt-diagnosis-of-st-elevation-myocardial-infarction-with-papillary-muscle-rupture-by-point-of-care-ultrasound-in-the-emergency-department
#16
Koon Ho Cheung, Colin Graham Alexander
A previously healthy 61-year-old man presented to the emergency department with chest pain and dyspnoea for 6 hours. Examination revealed distress with an apical pansystolic murmur. Initial electrocardiogram showed sinus tachycardia and ST elevation in leads II, III, and aVF compatible with an inferior ST-elevation myocardial infarction. Point-of-care echocardiography in the emergency department showed a flail anterior mitral leaflet and severe mitral regurgitation, leading to a provisional diagnosis of papillary muscle rupture...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29025278/angiogenic-growth-factors-for-coronary-artery-disease-current-status-and-prospects
#17
Ming Guo, Jun-He Shi, Pei-Li Wang, Da-Zhuo Shi
Although there have been advances in coronary artery bypass grafting and percutaneous coronary intervention, patients who have ischemic coronary artery disease (CAD) are ineligible for revascularization due to suboptimal anatomy. Cardiac angiogenesis is not only a physiological response to ischemia or hypoxia but also a potential target of therapeutic strategies. For some time now, preclinical studies show a great enthusiasm on therapeutic angiogenesis for ischemic CAD. However, the latest trials provided the limited evidence on its efficacy...
January 1, 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29023185/effectiveness-of-low-intensity-laser-therapy-on-tissue-repair-following-saphenectomy-in-patients-who-underwent-coronary-artery-bypass-graft-a-randomized-double-blind-study
#18
Isabel Clarisse Albuquerque Gonzaga, Raimundo de Barros Araújo, Andréa Conceição Gomes Lima, Gilderlene Alves Fernandes, Paulo Sérgio Cortellazi, Rauirys Alencar de Oliveira, Renata Amadei Nicolau
OBJECTIVE: To verify the effectiveness of low-intensity laser therapy (LLLT) on tissue repair following saphenectomy during postoperative period in patients having undergone coronary artery bypass graft (CABG). MATERIALS AND METHODS: A randomized clinical trial, controlled and double-blind study was conducted with 40 volunteers, divided into 2 groups: a placebo group (PG, n = 20) and a laser group (LG, n = 20). The patients in the LG group were irradiated with laser during saphenectomy (InGaAlP, λ 660 nm, energy density 6 J/cm(2)) daily from the first to the fourth postoperative day...
October 12, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29022414/iatrogenic-breast-infarct-following-coronary-artery-bypass-graft-surgery-with-harvesting-of-left-internal-mammary-artery
#19
Jacob Sweeney, Matthew Skovgard, Syed Hoda
No abstract text is available yet for this article.
October 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29021274/prevalence-and-outcomes-of-left-sided-valvular-heart-disease-associated-with-chronic-kidney-disease
#20
Zainab Samad, Joseph A Sivak, Matthew Phelan, Phillip J Schulte, Uptal Patel, Eric J Velazquez
BACKGROUND: Chronic kidney disease (CKD) is an adverse prognostic marker for valve intervention patients; however, the prevalence and related outcomes of valvular heart disease in CKD patients is unknown. METHODS AND RESULTS: Included patients underwent echocardiography (1999-2013), had serum creatinine values within 6 months before index echocardiogram, and had no history of valve surgery. CKD was defined as diagnosis based on the International Classification of Diseases, Ninth Revision or an estimated glomerular filtration rate <60 mL/min per 1...
October 11, 2017: Journal of the American Heart Association
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