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Fulminant myocarditis

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https://www.readbyqxmd.com/read/28496024/a-survival-case-of-fulminant-right-side-dominant-eosinophilic-myocarditis
#1
Keishi Moriwaki, Kaoru Dohi, Taku Omori, Muneyoshi Tanimura, Emiyo Sugiura, Shiro Nakamori, Toshiki Sawai, Kyoko Imanaka-Yoshida, Norikazu Yamada, Masaaki Ito
A 59-year-old Japanese woman was admitted to a nearby hospital with dyspnea and general malaise. Transthoracic echocardiography revealed right ventricular (RV) dilatation with severely reduced systolic function and leftward shift of the intraventricular septum. She was initially diagnosed with acute right heart failure, and fell into cardiogenic shock requiring an intra-aortic balloon pump and inotropic agents. An endomyocardial biopsy (EMB) demonstrated extensive interstitial edema, infiltration of inflammatory cells including numerous eosinophils, and myocytolysis with eosinophil degranulation...
May 12, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28489781/clinical-characteristics-and-outcomes-of-patients-with-myocarditis-mimicking-st-segment-elevation-myocardial-infarction-analysis-of-a-case-series
#2
Shuang Wu, Yan-Min Yang, Jun Zhu, Huai-Bin Wan, Juan Wang, Han Zhang, Xing-Hui Shao
Acute myocarditis mimicking ST-segment elevation myocardial infarction (STEMI) is highly deceptive for an accurate diagnosis, and a systematic study is lacking with regard to the clinical features and prognosis of this distinct clinical entity.Patients with suspected STEMI and eventually diagnosed with myocarditis by cardiac magnetic resonance (CMR) from January 2012 to April 2016 at Fuwai Hospital were identified by reviewing medical records and electronic databases. Follow-up was conducted by clinical visits and phone contacts in a median duration of 17 months...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28485549/immune-related-fulminant-myocarditis-in-a-patient-receiving-ipilimumab-therapy-for-relapsed-chronic-myelomonocytic-leukaemia
#3
David D Berg, Muthiah Vaduganathan, Anju Nohria, Matthew S Davids, Edwin P Alyea, Matthew Torre, Robert F Padera
No abstract text is available yet for this article.
May 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28451456/immunosuppressive-treatment-in-fulminant-myocarditis-and-gene-expression-pattern-associated-with-but-no-histological-confirmation-of-giant-cell-myocarditis
#4
Friedrich Fruhwald, Dirk Lassner, Sonja Fruhwald, Ulrich M Gross, Otto Dapunt, Heinz-Peter Schultheiss
A healthy woman with acute onset of pulmonary oedema and severely depressed left ventricular function underwent endomyocardial biopsy under the clinical suspicion of fulminant myocarditis. While awaiting the results of biopsy, the situation deteriorated to Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) and extracorporeal membrane oxygenation was implanted. Finally, immunohistochemistry in biopsy specimen corresponded to fulminant lymphocytic myocarditis, although active myocarditis was excluded...
May 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28409501/successful-treatment-of-fulminant-lyme-myocarditis-with-mechanical-circulatory-support-in-a-young-male-adult-a-case-report
#5
Željko Župan, Dino Mijatović, Igor Medved, Snježana Kraljić, Jurica Juranić, Berislav Barbalić, Marin Oštrić
We describe the case of fulminant myocarditis due to Lyme disease and use of mechanical circulatory support (MCS) for the treatment of the Lyme carditis associated with refractory cardiogenic shock. Fulminant Lyme myocarditis in young adult male patient led to a sudden onset of acute, severe biventricular heart failure with progressive cardiogenic shock, and multiorgan failure immediately after admission.
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28349221/total-artificial-heart-implantation-for-biventricular-failure-due-to-eosinophilic-myocarditis
#6
Masashi Kawabori, Chitaru Kurihara, Yair Miller, Kent A Heck, Roberta C Bogaev, Andrew B Civitello, William E Cohn, O H Frazier, Jeffrey A Morgan
Idiopathic hypereosinophilic syndrome is a condition of unknown etiology characterized by proliferation of eosinophils and their infiltration into tissues. Although cardiac involvement is rare, eosinophilic myocarditis can lead to life-threating fulminant congestive heart failure. Treatment of patients with eosinophilic myocarditis is challenging as heart failure can be caused by biventricular dysfunction. To our knowledge, this is the first case reported in the literature describing a patient with acute severe biventricular heart failure caused by eosinophilic myocarditis with mural left ventricular apical thrombus who was successfully treated with implantation of a total artificial heart as a bridge to heart transplant...
March 27, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/28320995/fulminant-myocarditis-with-prolonged-active-lymphocytic-infiltration-after-hemodynamic-recovery
#7
Muneyoshi Tanimura, Kaoru Dohi, Kyoko Imanaka-Yoshida, Taku Omori, Keishi Moriwaki, Shiro Nakamori, Norikazu Yamada, Masaaki Ito
Fulminant myocarditis is a highly mortal syndrome. Meanwhile, the clinical course in surviving patients is generally self-limiting. This is a rare case of fulminant myocarditis with prolonged lymphocytic infiltration after hemodynamic recovery. A 64-year-old man was diagnosed with fulminant myocarditis and required intensive care with veno-arterial extracorporeal membrane oxygenation. Left ventricular function gradually improved but complete atrioventricular block (CAVB) persisted. Follow-up endomyocardial biopsies (EMBs) showed prolonged active infiltration of lymphocytes along with (18)F-FDG uptake in (18)F-FDG PET/CT until about 70 days after the onset...
April 6, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28260935/post-influenza-aspergillosis-do-not-underestimate-influenza-b
#8
REVIEW
Eric Fl Nulens, Marc Jc Bourgeois, Marijke Bml Reynders
Our objective is to highlight and focus on post-influenza aspergillosis, triggered by influenza B virus. This relatively new clinical entity is often associated with a fulminant course of respiratory decline and high mortality. A 51-year immunocompetent woman, without any medical history or risk factors for developing a complicated influenza infection, was admitted to the intensive care unit. During admission, she presented with an afebrile flu-like syndrome, myocarditis, rhabdomyolysis, multiple organ failure, and evolved to severe respiratory distress...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/28255801/factors-and-values-at-admission-that-predict-a-fulminant-course-of-acute-myocarditis-data-from-tokyo-ccu-network-database
#9
Osamu Inaba, Yasuhiro Satoh, Mitsuaki Isobe, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
Prognosis of acute myocarditis is generally benign, but fulminant cases exist which require advanced life support devices, such as percutaneous cardio-pulmonary support (PCPS) and ventricular assist devices (VAD), and lead to fatal outcomes. The purpose of this study was to identify predictors and their values at admission which might foreshadow a fulminant course of myocarditis. Data from 138 patients (mean age 42.0 years, 79 males) with a diagnosis of acute myocarditis in the Tokyo CCU Network database from 2007 to 2009 were analyzed retrospectively...
March 3, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28226202/predictors-of-acute-myocarditis-in-complicated-scrub-typhus-an-endemic-province-in-the-republic-of-korea
#10
Jung Yeon Chin, Ki-Woon Kang, Kyung Min Moon, Jongwoo Kim, Yu Jeong Choi
Background/Aims: Scrub typhus is known as a self-limited infectious disease. Cardiac complication is uncommon and usually not life-threatening. Until now, few cases of fulminant myocarditis by scrub typhus have been reported. So, we investigated incidence and predictors of acute myocarditis in severe scrub typhus. Methods: We retrospectively reviewed 89 patients among 91 scrub typhus confirmed patients who examined an echocardiogram and cardiac biomarkers from 2005 to 2015 in the intensive care unit at our hospital...
February 23, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28220466/cardiovascular-toxicities-associated-with-cancer-immunotherapies
#11
REVIEW
Daniel Y Wang, Gosife Donald Okoye, Thomas G Neilan, Douglas B Johnson, Javid J Moslehi
PURPOSE OF REVIEW: We review the cardiovascular toxicities associated with cancer immune therapies and discuss the cardiac manifestations, potential mechanisms, and management strategies. RECENT FINDINGS: The recent advances in cancer immune therapy with immune checkpoint inhibitors and adoptive cell transfer have improved clinical outcomes in numerous cancers. The rising use of cancer immune therapy will lead to a higher incidence in immune-related adverse events...
March 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28161113/-myocarditis
#12
G Hékimian, A Combes
Acute myocarditis must be considered in patients with recent onset of cardiac failure or arrhythmia. Fulminant myocarditis is a distinct entity characterized by sudden onset of severe congestive heart failure or cardiogenic shock, usually following a flu-like illness, parvovirus B19, human herpesvirus 6, coxsackie virus and adenovirus being the most frequently viruses responsible for the disease. In this setting, early recognition of patients rapidly progressing to refractory cardiac failure and their immediate transfer to a medical-surgical center experienced in mechanical circulatory support is warranted...
February 1, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28131563/successful-extracorporeal-membrane-oxygenation-in-a-patient-with-fulminant-lupus-myocarditis
#13
Raúl Castellanos-Moreira, Sebastián Rodríguez-García, Teresa López-Sobrino, Aina Capdevila, Sergio Prieto-González, Gerard Espinosa
No abstract text is available yet for this article.
January 25, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28018687/fatal-dengue-myocarditis-despite-the-use-of-extracorporeal-membrane-oxygenation
#14
Yee-Huang Ku, Wen-Liang Yu
Dengue is an important mosquitoes-borne viral disease which is endemic in tropics and subtropics region. Rapid spreading of disease to previously unaffected region was found in recent years. Atypical manifestations, such as myocarditis, were reported during large outbreak. There is a wide range of clinical manifestations of cardiac involvement in dengue, but rarely fatal. Here we reported a case of fulminant dengue myocarditis in fatal outcome despite cardiac mechanical support.
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28005585/penicillin-induced-fulminant-myocarditis-a-case-report-and-review-of-the-literature
#15
REVIEW
Mehdi Ben Khelil, Youssef Chkirbene, Mona Mlika, Slim Haouet, Moncef Hamdoun
Drug-induced eosinophilic myocarditis is uncommon with few cases reported in the literature. It is a rare but potentially life-threatening disease.We report the case of an 11-year-old girl without medical history who developed an acute malaise and chills, followed by severe shortness of breath and a cardiopulmonary arrest 1 hour after an intramuscular injection of penicillin.At autopsy, we observed in the external examination nonspecific asphyxia signs, an injection mark, and the absence of traumatic signs...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/27994968/a-retrospective-study-cardiac-mri-of-fulminant-myocarditis-in-children-can-we-evaluate-the-short-term-outcomes
#16
Haipeng Wang, Bin Zhao, Haipeng Jia, Fei Gao, Junyu Zhao, Cuiyan Wang
BACKGROUND: Fulminant myocarditis (FM) is an inflammatory disease of the myocardium that results in ventricular systolic dysfunction and causes acute-onset heart failure. Cardiac magnetic resonance (CMR) has become the primary noninvasive tool for the diagnosis and evaluation of myocarditis. The aim of our study was to assess the CMR findings at different course of FM and the short-term outcomes of fulminant myocarditis (FM) in children. METHODS: Eight FM children with CMR examinations were included in our study...
2016: PeerJ
https://www.readbyqxmd.com/read/27909839/biventricular-support-using-a-centrifugal-pump-in-a-6%C3%A2-year-old-with-fulminant-myocarditis
#17
Hiromu Kehara, Tamaki Takano, Takamitsu Terasaki, Kenji Okada
We experienced a case of ventricular assist with both a pulsatile-flow and a continuous-flow pump in a pediatric patient, and herein report the clinical course and characteristics of the pumps. A 6-year-old female was diagnosed with fulminant myocarditis and transferred to our hospital for mechanical support. After 12 days of extracorporeal membrane oxygenation, we implanted a left ventricular assist device (LVAD) and a right ventricular assist device (RVAD) using centrifugal Gyro pumps with a membrane oxygenator in a paracorporeal fashion...
December 1, 2016: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/27878629/clinical-outcomes-in-pediatric-patients-hospitalized-with-fulminant-myocarditis-requiring-extracorporeal-membrane-oxygenation-a-meta-analysis
#18
REVIEW
Haolan Xiong, Bingqing Xia, Jingyu Zhu, Binfei Li, Wenqi Huang
We conducted a meta-analysis to provide the survival rates for pediatric patients hospitalized with fulminant myocarditis requiring ECMO. The literature search was conducted using Embase, PubMed, MEDLINE and Elsevier for studies published before April 1, 2016. We focus on survival rates for pediatric patients hospitalized with fulminant myocarditis requiring ECMO, and studies that reported only on adult patients were excluded. Summary of the survival rates was obtained using fixed-effect or random-effect meta-analysis which determined by I (2)...
February 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/27858465/established-and-novel-treatment-options-in-acute-myocarditis-with-or-without-heart-failure
#19
REVIEW
George Lazaros, Evangelos Oikonomou, Dimitris Tousoulis
Acute myocarditis is a disorder characterized by an unpredictable clinical course which ranges from asymptomatic, incidentally discovered forms, to cases with fulminant course and adverse outcome. The most challenging issues in the context of acute myocarditis are the appearance of difficult to treat heart failure in the acute phase and the potential progression in the long-term to dilated cardiomyopathy. Areas covered: With respect to available treatment options in acute myocarditis, in the absence of specific guidelines, management is supportive and overall empirical, especially for the oligo- or asymptomatic patients with preserved ejection fraction...
January 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/27829640/experiences-with-aggressive-cardiac-rehabilitation-in-pediatric-patients-receiving-mechanical-circulatory-supports
#20
Rie Amao, Teruhiko Imamura, Yusuke Sawada, Sachiko Endo, Shinichi Ozaki, Kenichi Okamura, Akihiro Masuzawa, Tetsuhiro Takaoka, Yasutaka Hirata, Takahiro Shindo, Minoru Ono, Nobuhiko Haga
Although some patients with fulminant myocarditis can be rescued owing to the improvements in mechanical circulatory support therapy, there are few reports providing evidence of cardiac rehabilitation during mechanical circulatory supports, particularly among pediatric patients. We treated two pediatric patients who underwent aggressive cardiac rehabilitation during mechanical support. Five days after the initiation of extracorporeal membrane oxygenation therapy aggressive cardiac rehabilitation was started in a 10-year-old girl with fulminant myocarditis...
December 2, 2016: International Heart Journal
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