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Pleural lavage cytology

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https://www.readbyqxmd.com/read/29756323/primary-mediastinal-histiocytic-sarcoma-presenting-as-pleural-effusion
#1
Jie-Yang Jhuang, Wei-Yu Chen, Shih-Sung Chuang
Histiocytic sarcoma (HS) is a rare malignant neoplasm showing morphological and immunophenotypic features of mature tissue histiocytes. As HS may mimic non-Hodgkin lymphoma (NHL) pathologically, before the era of immunohistochemistry, many previously reported cases were misdiagnosed NHL. Up to date, there are only a few reports delineating the cytological features in fine-needle aspiration or bronchoalveolar lavage, but not in the effusion fluid yet. Herein, we report the case of a 61-year-old male with a mediastinal tumor presenting with malignant pleural effusion...
May 13, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29628439/pleural-lavage-cytology-after-lung-resection-in-patients-with-non-small-cell-lung-cancer-and-the-feasibility-of-20-ml-saline-solution
#2
Toru Nakamura, Yoshiro Otsuki, Hidenori Nakamura, Kazuhito Funai
BACKGROUND: There are two issues to be discussed in pleural lavage cytology (PLC) for resected non-small cell lung cancer (NSCLC) whether it should be performed before (pre-PLC) or after (post-PLC) the lung resection and the dose of saline varies widely among the institutions. METHODS: We retrospectively reviewed the clinical records of 466 consecutive patients who underwent a curative resection for NSCLC and received both a pre- and post- PLC using 20 mL of saline from January 2001 to December 2011...
April 5, 2018: Asian Journal of Surgery
https://www.readbyqxmd.com/read/29620164/rapid-point-of-care-testing-for-epidermal-growth-factor-receptor-gene-mutations-in-patients-with-lung-cancer-using-cell-free-dna-from-cytology-specimen-supernatants
#3
Shiho Asaka, Akihiko Yoshizawa, Kazusa Saito, Yukihiro Kobayashi, Hiroshi Yamamoto, Tatsuya Negishi, Rie Nakata, Kazuyuki Matsuda, Akemi Yamaguchi, Takayuki Honda
Epidermal growth factor receptor (EGFR) mutations are associated with responses to EGFR tyrosine kinase inhibitors (EGFR-TKIs) in non-small-cell lung cancer (NSCLC). Our previous study revealed a rapid point-of-care system for detecting EGFR mutations. This system analyzes cell pellets from cytology specimens using droplet-polymerase chain reaction (d-PCR), and has a reaction time of 10 min. The present study aimed to validate the performance of the EGFR d-PCR assay using cell-free DNA (cfDNA) from supernatants obtained from cytology specimens...
June 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29318026/broncholithiasis-associated-with-lower-airway-inflammation-and-subsequent-pyothorax-in-a-cat
#4
Ferran Valls Sanchez, Jennifer Stewart, Catherine Bovens, Jordi Puig
Case summary: A 12-year-old female spayed domestic shorthair cat presented with history of a long-term chronic cough that had worsened during the previous 2 months. Thoracic radiographs revealed numerous mineral opacities throughout the lung fields. Multiple bronchial plugs of pale yellow material were present on bronchoscopy, consistent with broncholithiasis. Bronchoalveolar lavage cytology revealed a mild neutrophilic inflammation and bacterial culture was negative. The cat was diagnosed with chronic inflammatory lower airway disease and broncholithiasis, suspected to be due to mineralisation of secretions in the bronchial lumen...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29093430/epidermal-growth-factor-receptor-gene-mutation-in-pleural-lavage-cytology-findings-of-primary-lung-adenocarcinoma-cases
#5
Takashi Inoue, Yuji Matsumura, Osamu Araki, Yoko Karube, Sumiko Maeda, Satoru Kobayashi, Masayuki Chida
PURPOSE: In the present study, we examined the relationship between intraoperative pleural lavage cytology findings and presence of epidermal growth factor receptor (EGFR) gene mutations. METHODS: We investigated 160 patients who underwent surgical treatment for primary lung adenocarcinoma at our hospital from January 2011 to December 2013 to determine the presence of EGFR gene mutations and pleural lavage cytology. RESULTS: In all, 52 subjects (31...
February 20, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29039588/a-panel-of-markers-for-identification-of-malignant-and-non-malignant-cells-in-culture-from-effusions
#6
Fabiana Pirani Carneiro, Maria Imaculada Muniz-Junqueira, Fabio Pittella-Silva, Marcos de Vasconcelos Carneiro, Gustavo Henrique Soares Takano, Leonora Maciel de Sousa Vianna, Luciano Barbosa De Andrade, Tercia Maria Mendes Lousa De Castro, Isabela Peres, Tatiana Karla Dos Santos Borges, Vânia Moraes Ferreira, Andrea Barretto Motoyama
The aim of the present study was to identify cell types in primary culture from malignant and non-malignant effusions. Effusion samples were subjected to cytology and culture. Immunocytochemistry was performed in cytological slides to evaluate malignancy (positivity for malignancy markers) and in culture slides for identification of cell types in growth. A total of 143 effusion samples (pleural n=76; peritoneal n=37; pericardial n=4; and peritoneal lavage n=26) were analyzed. Cell growth was observed in 34...
October 11, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28875338/the-significance-of-scc-and-cea-mrna-in-the-pleural-cavity-after-lymphadenectomy-in-esophageal-cancer-patients-who-underwent-preoperative-treatment
#7
Keijiro Sugimura, Hiroshi Miyata, Masaaki Motoori, Takeshi Omori, Yoshiyuki Fujiwara, Masahiko Yano
BACKGROUND: This report focuses on the surgical manipulation and spread of cancer cells. Our previous study suggested an association between a poor prognosis and positive pleural lavage cytology after resection of esophageal cancer without preoperative treatment. However, little is known regarding the clinical significance of the lavage procedure in esophageal cancer patients who undergo preoperative treatment. METHODS: A cohort of 94 patients with squamous cell carcinoma of the esophagus who underwent esophagectomy with radical lymph node dissection was prospectively analyzed for free cancer cells in the pleural cavity after mediastinal lymphadenectomy...
March 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/28838382/assessing-the-prognostic-impact-of-the-international-association-for-the-study-of-lung-cancer-proposed-definitions-of-complete-uncertain-and-incomplete-resection-in-non-small-cell-lung-cancer-surgery
#8
Matteo Gagliasso, Giuseppe Migliaretti, Francesco Ardissone
OBJECTIVE: The aim of this study was to assess the prognostic impact of the definitions of complete, uncertain, and incomplete resection in non-small cell lung cancer (NSCLC) surgery, as proposed by the International Association for the Study of Lung Cancer (IASLC). PATIENTS AND METHODS: Single institution retrospective study of consecutive patients undergoing surgery for NSCLC between 1998 and 2007. Complete resection was defined by absence of gross and microscopic residual disease; systematic nodal dissection; no extracapsular extension in distal lymph nodes; and negativity of the highest mediastinal node removed...
September 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28485830/diagnosis-and-management-of-pyothorax-in-a-domestic-ferret-mustela-putorius-furo
#9
Izidora Sladakovic, Benjamin M Brainard, Selena L Lane, Scott A Secrest, Andrew J Fox, Jaime L Tarigo, Corry K Yeuroukis, Susan Sanchez, Laila M Proenca, Joerg Mayer
OBJECTIVE: To describe the diagnosis, management, and outcome of pyothorax in a domestic ferret (Mustela putorius furo). CASE SUMMARY: A domestic ferret was evaluated for a history of lethargy, anorexia, and pyrexia. Pleural effusion was detected with radiography and ultrasonography, and a diagnosis of pyothorax was made following cytologic evaluation of pleural fluid. Bilateral thoracostomy tubes were placed for thoracic drainage and lavage, and the ferret was treated with intravenous crystalloid fluids, antimicrobials, and analgesics...
July 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28474203/characteristics-and-timing-of-recurrence-during-postoperative-surveillance-after-curative-resection-for-lung-adenocarcinoma
#10
Terumoto Koike, Tatsuya Goto, Akihiko Kitahara, Seijiro Sato, Masayuki Saitoh, Takehisa Hashimoto, Osamu Namura, Masashi Takahashi, Shin-Ichi Toyabe, Masanori Tsuchida
PURPOSE: To establish the most effective methods of postoperative surveillance to detect early recurrence of lung adenocarcinoma. METHODS: The subjects of this retrospective study were 485 patients with p-stage I-III lung adenocarcinoma, who underwent postoperative surveillance. We examined the sites and detection modes of recurrence and calculated the recurrence-free probabilities. Patients with stage I disease were divided into low- and high-risk recurrence groups using a risk score calculated by assigning points proportional to risk factor regression coefficients...
December 2017: Surgery Today
https://www.readbyqxmd.com/read/28195650/cell-tube-block-a-new-technique-to-produce-cell-blocks-from-fluid-cytology-samples
#11
Ricardo Marcos, Marta Santos, Carla Marrinhas, Mario Caniatti
BACKGROUND: Cell blocks are widely used in human cytopathology. Several techniques have been proposed to convert fluid specimens into solid material, which after embedding in paraffin can be used for histochemistry, immunohistochemistry, or molecular testing. In contrast, only in the last few years, have cell blocks begun to be used in the veterinary field. OBJECTIVES: The purpose of the study was to present the production and features of cell tube blocks (CTB) with veterinary liquid samples...
March 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/27987590/prognostic-impact-of-pleural-lavage-cytology-in-patients-with-primary-lung-cancer
#12
Kenji Tomizawa, Masaya Nishino, Yuichi Sesumi, Yoshihisa Kobayashi, Katsuaki Sato, Masato Chiba, Masaki Shimoji, Kenichi Suda, Shigeki Shimizu, Takao Sato, Toshiki Takemoto, Tetsuya Mitsudomi
OBJECTIVES: Positive pleural lavage cytology (PLC) has been reported to have a negative prognostic impact in patients with surgically resected non-small cell lung cancer (NSCLC). However, positive PLC does not upgrade the stage according to the 7th edition of TNM classification for lung cancer. The objectives of this study were to evaluate the prognostic impact of positive PLC in patients with NSCLC and to clarify its contribution to TNM classification. MATERIALS AND METHODS: Seven hundred fifty-four patients who underwent surgical resection of NSCLC from January 2007 through December 2013 were retrospectively studied...
December 2016: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/27476564/-lung-cancer-incidentally-detected-by-a-subcutaneous-nodule-at-the-drainage-site-for-pneumothorax
#13
Jumpei Okamoto, Isao Matsumoto, Daisuke Saito, Shuhei Yoshida, Munehisa Takada, Masaya Tamura, Hirofumi Takemura, Hiroko Ikeda
A 43-year-old male patient underwent thoracic drainage for the treatment of right pneumothorax. After 6 months, the patient visited our department because of a subcutaneous nodule found at the drainage site. Chest computed tomography revealed a mass lesion associated with a cavity in the right upper lobe of the lung and a subcutaneous nodule. Surgical resection was performed and both the pulmonary lesion and subcutaneous nodule were found to be adenocarcinoma. Although immunohistochemical analysis suggested that the pulmonary lesion was primary lung cancer, there were neither intrathoracic exposure of the tumor nor tumor cells in the pleural lavage cytology...
August 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27458805/prognostic-value-of-pleural-lavage-cytology-in-patients-with-lung-cancer-resection-an-updated-meta-analysis
#14
Chun-Mei Wang, Zhou-Gui Ling, Yan-Bin Wu, Shuang-Qi Cai, Zhen-Ming Tang, Cong Wu, Yi-Qiang Chen
OBJECTIVE: Pleural lavage cytology (PLC) is considered as a possible tool for assessing prognosis of lung cancer patients. We aimed to comprehensively review the prognosis value of PLC in patients undergoing surgical resection. METHODS: We searched 4 electronic databases for relevant studies comparing positive PLC and negative PLC. The primary outcomes included survival rate and recurrence rate at maximum follow-up. RESULTS: The meta-analysis included 28 studies, with a total of 20,714 patients...
2016: PloS One
https://www.readbyqxmd.com/read/27159517/pathology-image-of-the-month-cough-and-shortness-of-breath-in-a-noncompliant-patient-with-hiv-aids
#15
Reggie Thomasson, Tracy Dewenter, Robin R McGoey
A 37- year-old man with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) was admitted to the intensive care unit following a four month history of progressive shortness of breath, productive cough, and flu-like symptoms. His HIV/AIDS was diagnosed at the age of 19 (CD4 count =15; viral load = 294,436 copies/ mL) and was complicated by hemodialysis-dependent, HIV-associated nephropathy, prior Pneumocystis pneumonia and known noncompliance with prescribed antiretroviral therapy. Chest film at admission was interpreted as diffuse bilateral interstitial and airspace opacities with a right sided layering density representative of laminar pleural effusion...
July 2015: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27138544/pathology-image-of-the-month-cough-and-shortness-of-breath-in-a-noncompliant-patient-with-hiv-aids
#16
Reggie Thomasson Md, Tracy Dewenter Md, Robin R McGoey Md
A 37- year-old man with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) was admitted to the intensive care unit following a four month history of progressive shortness of breath, productive cough, and flu-like symptoms. His HIV/AIDS was diagnosed at the age of 19 (CD4 count =15; viral load = 294,436 copies/ mL) and was complicated by hemodialysis-dependent, HIV-associated nephropathy, prior Pneumocystis pneumonia and known noncompliance with prescribed antiretroviral therapy. Chest film at admission was interpreted as diffuse bilateral interstitial and airspace opacities with a right sided layering density representative of laminar pleural effusion...
July 2015: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27055072/malignant-pleural-effusions-because-of-lung-cancer
#17
REVIEW
José M Porcel
PURPOSE OF REVIEW: The discovery of a pleural effusion in the setting of lung cancer has diagnostic, prognostic, and therapeutic challenges, some of which are addressed in this review. RECENT FINDINGS: Around 20% of patients with lung cancer have minimal pleural effusions, which are not amenable to a diagnostic thoracentesis. These patients have a poorer overall survival (∼7.5 months) than those without effusions (∼12-18 months), although slightly better than those with proven malignant fluids (∼5...
July 2016: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/27038519/uvaol-attenuates-pleuritis-and-eosinophilic-inflammation-in-ovalbumin-induced-allergy-in-mice
#18
Lais Costa Agra, Marvin Paulo Lins, Patrícia da Silva Marques, Salete Smaniotto, Christianne Bandeira de Melo, Vincent Lagente, Emiliano Barreto
Uvaol, a triterpene present in olives and virgin olive oil, has been shown to possess anti-inflammatory properties and antioxidant effects. However, until now, no studies have demonstrated its potential effects on allergic inflammation. The aim of this study was to evaluate the anti-inflammatory effects of uvaol in a mouse model of allergy characterized by eosinophil-dominant inflammation in actively sensitized mice. The anti-inflammatory effect of uvaol was analyzed in two murine models of allergic inflammation (pleurisy and asthma)...
June 5, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27012585/the-impact-of-pleural-lavage-cytology-both-before%C3%A2-and-after-lung-resection-on-recurrence-of%C3%A2-non-small-cell-lung-cancer
#19
COMPARATIVE STUDY
Fumihiro Shoji, Koji Yamazaki, Hidenori Kouso, Ryo Mori, Sadanori Takeo
BACKGROUND: Pleural lavage cytology (PLC) involves cytologic examination during surgery for non-small cell lung cancer (NSCLC). The timing regarding the performance of PLC is potentially important; however, a consensus remains to be established. We sought to retrospectively analyze the impact of PLC both before (pre-PLC) and after (post-PLC) lung resection on recurrence in NSCLC. METHODS: From July 1994 to December 2011, 700 consecutive patients with surgically resected NSCLC were selected...
June 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26992116/role-of-epstein-barr-virus-status-and-immunophenotypic-studies-in-the-evaluation-of-exfoliative-cytology-specimens-from-patients-with-post-transplant-lymphoproliferative-disorders
#20
Sarah E Gibson, Jennifer Picarsic, Steven H Swerdlow, Liron Pantanowitz
BACKGROUND: Post-transplant lymphoproliferative disorders (PTLDs) are well characterized in tissue sections, but their evaluation in exfoliative cytology specimens is limited. This study reports a 25-year experience with PTLDs in exfoliative cytology specimens. METHODS: All solid organ or allogeneic stem cell transplant recipients with PTLDs and exfoliative cytology specimens from 1987 to 2011 were identified. The cytomorphology, Epstein-Barr virus (EBV) status, flow cytometry, immunohistochemistry, and molecular studies were reviewed from all exfoliative cytology specimens previously diagnosed as atypical lymphoid proliferations or PTLDs...
June 2016: Cancer Cytopathology
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