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https://www.readbyqxmd.com/read/28544834/in-vitro-pulsatile-flow-measurement-in-prosthetic-heart-valves-an-inter-laboratory-comparison
#1
Stephen M Retta, Jeff Kepner, Salvador Marquez, Bruce A Herman, Mark C S Shu, Laurence W Grossman
BACKGROUND AND AIM OF STUDY: One of the first steps in qualifying a new prosthetic valve for eventual clinical use is preclinical flow performance testing in vitro. Such testing is typically performed in an in-vitro test system that simulates the pumping mechanics of the left ventricle of the heart, generally referred to as a pulse duplicator or duplicator. Historically, test results in these systems have varied from duplicator to duplicator. This collaborative effort between heart valve manufacturers and the Food and Drug Administration (FDA) was designed to evaluate the variability of the pulse duplicator test technology for pulsatile flow performance measurement in an interlaboratory round robin...
January 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28543756/perventricular-device-closure-of-doubly-committed-sub-arterial-ventricular-septal-defects-via-a-left-infra-axillary-approach
#2
Sijie Zhou, Liyun Zhao, Taibing Fan, Bin Li, Weijie Liang, Haoju Dong, Shubo Song, Lin Liu
BACKGROUND: This study sought to evaluate the feasibility, safety, and efficacy of perventricular device closure of a doubly committed sub-arterial ventricular septal defect (dcVSD) through a left infra-axillary approach. METHOD: Forty-five patients, with a dcVSD of less than 8 mm in diameter, were enrolled in this study. The pericardium was exposed and opened through a left infra-axillary mini-incision. Two parallel purse-string sutures were placed on the right ventricle outflow tract and under transesophageal echocardiography guidance, a delivery sheath loaded with the device was inserted into the right ventricle and advanced through the defect into the left ventricle...
May 24, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28543216/bridging-with-tirofiban-during-oral-antiplatelet-interruption-a-single-center-case-series-analysis-including-patients-on-hemodialysis
#3
Elizabeth A Walker, William E Dager
INTRODUCTION: Surgical patients requiring an interruption in dual-antiplatelet therapy (DAPT) within 6 months of cardiac stenting are at risk for thrombotic events. Bridging with short-acting intravenous antiplatelet agents has been proposed to minimize the risk of thrombotic and hemorrhagic complications. METHODS: This was a retrospective analysis of a tirofiban bridging strategy that did not use an initial bolus loading dose. Tirofiban infusions were initiated 24to 48 hours after the last oral antiplatelet dose at a rate of 0...
May 23, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28538468/hearing-preservation-in-pediatric-cochlear-implantation
#4
Matthew L Carlson, Neil S Patel, Nicole M Tombers, Melissa D DeJong, Alyce I Breneman, Brian A Neff, Colin L W Driscoll
OBJECTIVE: Currently, there is a paucity of literature evaluating hearing preservation outcomes in children following cochlear implantation. The objective of the current study is to report pediatric hearing preservation results following cochlear implantation with conventional full-length electrodes. STUDY DESIGN: Retrospective review (2000-2016). SETTING: Tertiary referral center. PATIENTS: All pediatric patients with a ≤ 75 dB preoperative low-frequency pure tone average (LFPTA; 250-500 Hz average), who underwent cochlear implantation with a conventional length electrode...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28535307/intergenerational-impact-of-paternal-lifetime-exposures-to-both-folic-acid-deficiency-and-supplementation-on-reproductive-outcomes-and-imprinted-gene-methylation
#5
Lundi Ly, Donovan Chan, Mahmoud Aarabi, Mylène Landry, Nathalie A Behan, Amanda J MacFarlane, Jacquetta Trasler
STUDY QUESTION: Do paternal exposures to folic acid deficient (FD), and/or folic acid supplemented (FS) diets, throughout germ cell development adversely affect male germ cells and consequently offspring health outcomes? SUMMARY ANSWER: Male mice exposed over their lifetimes to both FD and FS diets showed decreased sperm counts and altered imprinted gene methylation with evidence of transmission of adverse effects to the offspring, including increased postnatal-preweaning mortality and variability in imprinted gene methylation...
May 23, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28534597/metabolomics-for-improving-pregnancy-outcomes-in-women-undergoing-assisted-reproductive-technologies
#6
REVIEW
Charalampos S Siristatidis, Eleni Sertedaki, Dennis Vaidakis
BACKGROUND: In order to overcome the low effectiveness of assisted reproductive technologies (ART) and the high incidence of multiple births, metabolomics is proposed as a non-invasive method to assess oocyte quality, embryo viability, and endometrial receptivity, and facilitate a targeted subfertility treatment. OBJECTIVES: To evaluate the effectiveness and safety of metabolomic assessment of oocyte quality, embryo viability, and endometrial receptivity for improving live birth or ongoing pregnancy rates in women undergoing ART, compared to conventional methods of assessment...
May 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28533807/malignant-soft-tissue-sarcoma-of-the-shoulder-treated-by-surface-mould-brachytherapy-boost-in-an-adjuvant-setting
#7
Ashutosh Mukherji, Mourougan Sinnatamby
PURPOSE: Soft tissue sarcomas of the extremities account for half of all soft tissue sarcomas. Radiotherapy and surgery have been the standard modalities in the treatment of this type of cancer. Brachytherapy can be used as the sole therapy, if the target volume is localized and easily accessible. This work reports three cases of shoulder soft tissue sarcomas with positive deep resected margins, treated with a combination of external beam radiotherapy and surface mould brachytherapy boost technique...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28533802/interobserver-variations-of-target-volume-delineation-and-its-impact-on-irradiated-volume-in-accelerated-partial-breast-irradiation-with-intraoperative-interstitial-breast-implant
#8
Ritu Raj Upreti, Ashwini Budrukkar, Tabassum Wadasadawala, Shagun Misra, Lavanya Gurram, Rima Pathak, Deepak D Deshpande
PURPOSE: To investigate the interobserver variations in delineation of lumpectomy cavity (LC) and clinical target volume (CTV), and its impact on irradiated volume in accelerated partial breast irradiation using intraoperative multicatheter brachytherapy. MATERIAL AND METHODS: Delineation of LC and CTV was done by five radiation oncologists on planning computed tomography (CT) scans of 20 patients with intraoperative interstitial breast implant. Cavity visualization index (CVI), four-point index ranging from (0 = poor) to (3 = excellent) was created and assigned by observers for each patient...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28531369/should-high-bmi-be-a-reason-for-ivf-treatment-denial
#9
S Friedler, O Cohen, G Liberty, B Saar-Ryss, S Meltzer, T Lazer
Our aim was to examine the influence of BMI on the live-birth rate following IVF/ICSI and evaluate its specific contribution among other factors thus enabling accurate reproductive policy development. All patients that underwent IVF/ICSI at our center during January 2012-July 2015 were included in this retrospective study. A total of 1654 ICSI cycles were divided into four groups according to the patient's BMI (kg/m(2)): group I (normal weight): <25 (943 cycles); group II (overweight): 25-30 (403 cycles); group III (obese): 30-35 (212 cycles); group IV (morbid obesity): >35 (96 cycles)...
May 20, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28530033/concomitant-contraceptive-implant-and-efavirenz-use-in-women-living-with-hiv-perspectives-on-current-evidence-and-policy-implications-for-family-planning-and-hiv-treatment-guidelines
#10
REVIEW
Rena C Patel, Chelsea Morroni, Kimberly K Scarsi, Tabitha Sripipatana, James Kiarie, Craig R Cohen
INTRODUCTION: Preventing unintended pregnancies is important among all women, including those living with HIV. Increasing numbers of women, including HIV-positive women, choose progestin-containing subdermal implants, which are one of the most effective forms of contraception. However, drug-drug interactions between contraceptive hormones and efavirenz-based antiretroviral therapy (ART) may reduce implant effectiveness. We present four inter-related perspectives on this issue. DISCUSSION: First, as a case study, we discuss how limited data prompted country-level guidance against the use of implants among women concomitantly using efavirenz in South Africa and its subsequent negative effects on the use of implants in general...
May 11, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28529111/the-results-of-total-hip-arthroplasty-after-sugioka-transtrochanteric-anterior-rotational-osteotomy-for-osteonecrosis
#11
Takeshi Utsunomiya, Goro Motomura, Satoshi Ikemura, Satoshi Hamai, Jun-Ichi Fukushi, Yasuharu Nakashima
BACKGROUND: Since Sugioka transtrochanteric anterior rotational osteotomy (ARO) for osteonecrosis of the femoral head (ONFH) changes the morphology of the proximal femur, total hip arthroplasty (THA) after previous ARO is considered a technically demanding procedure. The purpose of this study was to compare the clinicoradiologic outcomes of THA after ARO with those of THA without any antecedent surgery for ONFH. METHODS: Twenty-four hips in 20 patients who underwent cementless THA after ARO (postosteotomy group) were retrospectively reviewed and compared with patients who underwent cementless THA without any antecedent surgery for ONFH during the same period (primary group)...
April 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28525324/in-vitro-effect-of-leptin-on-anterior-pituitary-cells-lh-secretory-activity-during-early-pregnancy-in-pig
#12
G Siawrys, A Gajewska
Leptin modulates reproductive activity but its potential influence on LH secretion from anterior pituitary (AP) cells during implantation period in pigs (days 14-16 of pregnancy) remained unexplored. This study focused on determination whether leptin affects basal and GnRH-induced LH secretion and intracellular accumulation and whether leptin receptor (OB-Rb) mRNA is expressed in the AP gland during implantation in pigs. Four individual AP glands were developed into separate primary cultures. 2×105 cells/ml were preincubated (72 h) and next, for 3...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28521965/evaluation-of-the-papilla-level-adjacent-to-implants-placed-in-fresh-healing-or-healed-sites-a-systematic-review
#13
REVIEW
M C Goiato, R A de Medeiros, E V F da Silva, D M Dos Santos
A better understanding of factors that can lead to papilla formation or recession, such as the type of site where the implant was placed, is of fundamental importance to the aesthetic success of the rehabilitation. The aim of this study was to perform a systematic review of the literature regarding the formation or recession of papilla adjacent to implants placed in fresh, healing or healed sites. The protocol for this study was registered in the PROSPERO database (registration number CRD 42016033784). An electronic search was performed by two independent reviewers who applied the inclusion and exclusion criteria on the PubMed/MEDLINE, Scopus, and Embase databases from January 2005 up to February 2016...
May 15, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28520812/the-effect-of-platelet-rich-plasma-on-osseous-healing-in-dogs-undergoing-high-tibial-osteotomy
#14
Samuel P Franklin, Emily E Burke, Shannon P Holmes
OBJECTIVES: The purpose of this study was to investigate whether platelet-rich plasma (PRP) enhances osseous healing in conjunction with a high tibial osteotomy in dogs. STUDY DESIGN: Randomized controlled trial. METHODS: Sixty-four client-owned pet dogs with naturally occurring rupture of the anterior cruciate ligament and that were to be treated with a high tibial osteotomy (tibial plateau leveling osteotomy) were randomized into the treatment or control group...
2017: PloS One
https://www.readbyqxmd.com/read/28518180/the-effects-of-laser-with-different-parameters-and-crosshatching-on-fibroblast-adhesion-and-proliferation-to-implant-surfaces
#15
Hakki Çelebi, Pembegül Uyar Arpacı, Ilhami Çelik, Serhan Akman
PURPOSE: To compare the adhesion and proliferation effect of HGF-1 cells on pure titanium disks when the surfaces are unprocessed (machined surfaces after slicing) or modified with a laser. MATERIALS AND METHODS: Twenty-eight titanium disks were divided into four groups. Three surface topographies were created using an erbium fiber laser: group 1 (unidirectional application [no crosshatch]), group 2 (crosshatching in two directions), and group 3 (crosshatching in three directions)...
May 18, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28516965/benefits-of-active-middle-ear-implants-over-hearing-aids-in-patients-with-sloping-high-tone-hearing-loss-comparison-with-hearing-aids
#16
J M Lee, J H Jeon, I S Moon, J Y Choi
In this retrospective chart review we compared the subjective and objective benefits of active middle ear implants (AMEIs) with conventional hearing aids (HAs) in patients with sloping high tone hearing loss. Thirty-four patients with sensorineural hearing loss were treated with AMEIs. Of these, six had sloping high tone hearing loss and had worn an HA for more than 6 months. Objective assessments, a pure-tone audiogram, as well as a word recognition test, and the Korean version of the Hearing in Noise Test (K-HINT), and a subjective assessment, the Abbreviated Profile of Hearing Aid Benefit (APHAB) questionnaire, were performed...
June 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28512551/consensus-statements-and-clinical-recommendations-on-treatment-indications-surgical-procedures-prosthetic-protocols-and-complications-following-all-on-4-standard-treatment-9th-mozo-grau-ticare-conference-in-quintanilla-spain
#17
REVIEW
Miguel Penarrocha-Diago, María Penarrocha-Diago, Regino Zaragozí-Alonso, David Soto-Penaloza, Meeting On Behalf Of The Ticare Consensus
OBJECTIVES: The present consensus report critically evaluates the scientific evidence based on a comprehensive systematic review of the All-On-4 treatment concept, focusing primarily on the treatment indications, surgical procedures and prosthetic protocols, and secondarily on the mechanical and biological complications involved. MATERIAL AND METHODS: A systematic review was made in advance of the meeting. Consensus statements, treatment guidelines and recommendations for future research were based on within-group as well as plenary debates and discussions of the systematic review...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28511422/posterior-chamber-scleral-fixation-of-intraocular-lenses-in-post-vitrectomised-aphakic-eyes
#18
Francis Kwasi Obeng, Vipan Kumar Vig, Preetam Singh, Rajbir Singh, Bodhraj Dhawan, Nikhil Sahajpal
INTRODUCTION: The best method of aphakia correction is in the bag implantation of Posterior Chamber Intraocular Lens (PCIOL). When this ideal procedure is not possible due to lack of integrity of posterior capsule or zonules, the other alternatives are broadly categorized into two: extraocular and intraocular. Whereas, the former includes contact lenses and aphakic glasses, the latter ones are further divided into anterior and posterior chamber methods. Anterior Chamber Intraocular Lenses (ACIOL) can be with or without iris claw...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510732/efficacy-of-bistrifluron-termite-bait-on-coptotermes-lacteus-isoptera-rhinotermitidae-in-southern-australia
#19
Garry A Webb
Bistrifluron, a benzoylphenyl urea compound, was evaluated for efficacy against Coptotermes lacteus (Froggatt), a mound-building species in southern Australia. Bistrifluron bait (tradename Xterm) was delivered as containerized pellets inserted into plastic in-ground feeding stations implanted in the sides of mounds. Termites actively tunneled in the gaps between pellets and removed bait from the canisters. Two separate trials were conducted, one commencing on 22 September 2011 and the second commencing on 30 November 2011...
May 16, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28508917/dowel-pinning-for-metacarpal-and-metatarsal-fractures-in-dogs
#20
Matthias Kornmayer, Ulrike Matis
OBJECTIVE: To evaluate a dowel pinning technique for metacarpal and metatarsal fractures in dogs. MATERIAL AND METHODS: Medical records of 13 dogs with complete clinical and radiographic follow-up examinations after a median observation time of 5 months were evaluated retrospectively. Assessment included fracture data, number of stabilized bones versus number of fractured bones and parameters of internal fixation including postoperative axial alignment and position of implants assessed on serial radiographs...
May 16, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
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