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Urethral pressure profilometry

Mario Klünder, Bastian Amend, Oliver Sawodny, Arnulf Stenzl, Michael Ederer, Alexandra Kelp, Karl-Dietrich Sievert, Ronny Feuer
INTRODUCTION: Recently, a new urodynamic method for the assessment of stress urinary incontinence called high definition urethral pressure profilometry (HD-UPP) has been introduced. This method combines a novel microtip catheter with advanced signal processing to enable spatial data location and the reconstruction of a pressure image inside the urethra. In order to assess the reproducibility of HD-UPP data, we statistically evaluate HD-UPP datasets and compare them to data from a double balloon air-charged system...
August 30, 2016: Neurourology and Urodynamics
Emilee J Luckring, Kathleen Ham, Christopher A Adin, Mary A McLoughlin, Jason W Stull
OBJECTIVE: To describe a laparoscopic approach for placement of a percutaneously controlled artificial urethral sphincter (AUS) in female cadaver dogs and compare the change in urethral pressure and lumen diameter after filling the device. STUDY DESIGN: Experimental study. ANIMALS: Canine female cadavers (n = 10). METHODS: A laparoscopic technique was used to implant the AUS in 10 cadaver dogs. Maximum urethral closure pressure (MUCP), cystourethral leak point pressure (CLPP), and urethral luminal area were measured at 0, 25, 50, and 75% cuff inflation...
June 28, 2016: Veterinary Surgery: VS
Bartosz Dybowski, Anna Burdzińska, Katarzyna Siewruk, Michał Dąbrowski, Leszek Pączek, Piotr Radziszewski
OBJECTIVES: To investigate the effects of propofol and isoflurane on urethral pressure profilometry of female dogs and goats, and to identify the method of anesthesia that least influences urethral pressure profilometry and to assess its reproducibility. METHODS: The effects of premedication with midazolam, propofol sedation and isoflurane anesthesia were assessed in five female dogs. The effects of propofol and isoflurane were compared in seven goats, whereas in another group of 19 goats, the state of deep propofol sedation was compared with the state of recovery from propofol sedation...
August 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
Mayank Mohan Agarwal, Saurabh Jain, Ravimohan Mavuduru, Shrawan K Singh, Arup K Mandal
INTRODUCTION: Dysfunctional voiding results from a disturbance in the coordination between sphincter relaxation and detrusor contraction. Video urodynamic studies with electromyography (EMG) are used for diagnosis but have limitations of availability and interpretation. We identified a plateau type voiding detrusor pressure tracing pattern in these patients with a potential of helping diagnosis. MATERIALS AND METHODS: Urodynamic data and tracings of adult patients having been diagnosed with external urethral sphincter dysfunction (EUSD) were retrospectively analyzed...
April 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
Kuralay Sharipova, Zane Pilsetniece, Ye Bekmukhambetov, Egils Vjaters
INTRODUCTION: The aim of the study was to analyse the correlation of subjective complaints and urethral pressure profilometry (UPP) data in women with different types of urinary incontinence (UI): stress UI (SUI), urgency UI (UUI), and mixed UI (MixUI). METHODS: A study group of 405 women with complaints about UI were surveyed (UDI-6; ICIQ-UI) to determine the subjectively dominant type of UI, and UPP was performed for all these women. The variables analysed by UPP were the maximum urethral closure pressure at rest (MUCPrest), maximum urethral closure pressure at cough stress (MUCPstress), functional urethral length at rest (FULrest), functional urethral length during cough stress (FULstress) test and pressure transmission ratio (PTR)...
2016: Urologia Internationalis
Mario Klünder, Oliver Sawodny, Bastian Amend, Michael Ederer, Alexandra Kelp, Karl-Dietrich Sievert, Arnulf Stenzl, Ronny Feuer
BACKGROUND: Urethral pressure profilometry (UPP) is used in the diagnosis of stress urinary incontinence (SUI) which is a significant medical, social, and economic problem. Low spatial pressure resolution, common occurrence of artifacts, and uncertainties in data location limit the diagnostic value of UPP. To overcome these limitations, high definition urethral pressure profilometry (HD-UPP) combining enhanced UPP hardware and signal processing algorithms has been developed. In this work, we present the different signal processing steps in HD-UPP and show experimental results from female minipigs...
2016: Biomedical Engineering Online
Mario Klunder, Ronny Feuer, Bastian Amend, Alexandra Kelp, Arnulf Stenzl, Karl-Dietrich Sievert, Oliver Sawodny, Michael Ederer
Urethral Pressure Profilometry (UPP) is a tool in the diagnosis of urinary incontinence. The pressure profile along the urethra is measured by a special catheter in order to assess the contraction strength of the sphincter muscle. The use of microtip catheters with several pressure sensors and an integrated acceleration sensor enables signal reconstruction of the pressure distribution on the urethra's inside. Experimental data from minipigs exhibit artifact patterns in the pressure data. It is shown that these artifacts are caused by vascular pulsation in the sphincter structure...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Maria Zubieta, Rebecca L Carr, Marcus J Drake, Kari Bø
INTRODUCTION AND HYPOTHESIS: Stress urinary incontinence (SUI) is managed with pelvic floor muscle training (PFMT), but the mechanism of treatment action is unclear. Resting maximal urethral closure pressure (MUCP) is lower in women with SUI, but it is unknown whether PFMT can alter resting MUCP. This systematic review evaluated whether voluntary pelvic floor muscle (PFM) contraction increases MUCP above its resting value (augmented MUCP) and the effect of PFMT on resting and augmented MUCP...
May 2016: International Urogynecology Journal
Mario Klünder, Bastian Amend, Martin Vaegler, Alexandra Kelp, Ronny Feuer, Karl-Dietrich Sievert, Arnulf Stenzl, Oliver Sawodny, Michael Ederer
INTRODUCTION: Urethral pressure profilometry (UPP) is used in the diagnosis of stress urinary incontinence (SUI). SUI is a significant medical, social, and economic problem, affecting about 12.5% of the population. A novel microtip catheter was developed for UPP featuring an inclination sensor and higher angular resolution compared to systems in clinical use today. Therewith, the location of each measured pressure sample can be determined and the spatial pressure distribution inside the urethra reconstructed...
July 24, 2015: Neurourology and Urodynamics
Odunayo Kalejaiye, Monika Vij, Marcus John Drake
INTRODUCTION: The relevant terminology for stress urinary incontinence (SUI) is affected by the context, namely the clinical assessment (the symptom of SUI elicited on history taking and the sign of SUI observed during examination) or diagnostic investigations (urodynamic stress incontinence). In some cases, SUI may only be observed after the reduction in coexistent prolapse (occult SUI). Classifying SUI often relies on distinguishing between intrinsic sphincter deficiency (ISD), and urethral malposition or hypermobility, although this potentially an over-simplification...
September 2015: World Journal of Urology
Cecile Tawadros, Katherine Burnett, Laura F Derbyshire, Thomas Tawadros, Noel W Clarke, Christopher D Betts
OBJECTIVE: To investigate by electromyography (EMG), the presence of complex repetitive discharges (CRDs) and decelerating bursts (DBs) in the striated external urethral sphincter during the menstrual cycle in female volunteers with no urinary symptoms and complete bladder emptying. SUBJECTS AND METHODS: Healthy female volunteers aged 20-40 years, with regular menstrual cycles and no urinary symptoms were recruited. Volunteers completed a menstruation chart, urinary symptom questionnaires, pregnancy test, urine dipstick, urinary free flow and post-void ultrasound bladder scan...
September 2015: BJU International
Wei Xin Yang, Hong Jun Zhu, Wei Guo Chen, Da Wei Zhang, Min Su, Jin Fa Feng, Chuan Dao Liu, Ping Cai
OBJECTIVE: To evaluate the effects of transrectal ultrasound-guided trocar catheter transurethral botulinum toxin A (BTX-A) injection into the external urethral sphincter (EUS) for treating detrusor external sphincter dyssynergia (DESD) in men with spinal cord injury (SCI). DESIGN: Descriptive study. SETTING: Hospital rehabilitation department. PARTICIPANTS: Patients (N=15; mean age, 40.5y; range, 22-64y) with suprasacral SCI with confirmed DESD determined by urodynamic study...
April 2015: Archives of Physical Medicine and Rehabilitation
Anna C Kirby, Jasmine Tan-Kim, Charles W Nager
OBJECTIVES: Female stress urinary incontinence is caused by urethral dysfunction during dynamic conditions, but current technology has limitations in measuring urethral pressures under these conditions. An 8-French high-resolution manometry (HRM) catheter currently in clinical use in gastroenterology may accurately measure urethral pressures under dynamic conditions because it has a 25-millisecond response rate and circumferential pressure sensors along the length of the catheter (ManoScan ESO; Given Imaging, Yoqneam, Israel)...
March 2015: Female Pelvic Medicine & Reconstructive Surgery
Yoshifumi Kadono, Satoru Ueno, Hiroshi Yaegashi, Mitsuo Ofude, Kouji Izumi, Yuji Maeda, Atsushi Mizokami, Sotaro Miwa, Tohru Miyagi, Mikio Namiki
OBJECTIVE: To evaluate continence status and mechanism of urinary incontinence immediately after robot-assisted radical prostatectomy (RARP) by performing urodynamic evaluation. METHODS: A total of 87 patients with localized prostate cancer who underwent RARP were included. Filling cystometry, urethral pressure profilometry, and abdominal leak point pressure (ALPP) tests were performed before and immediately after RARP. RESULTS: The mean urine loss ratio (ULR), calculated by dividing the total urine volume by the weight of urine loss after RARP, was 17...
July 2014: Urology
Saurabh Jain, Mayank Mohan Agarwal, Ravimohan Mavuduru, Shrawan K Singh, Arup K Mandal
OBJECTIVE: To investigate the accuracy of micturitional urethral pressure profilometry (MUPP) for diagnosis, grading, and localization of bladder outlet obstruction (BOO) in men with obstructive lower urinary tract symptoms. METHODS: This prospective study included adult men with voiding symptoms qualifying for urodynamics (UDS). Patients with urethral stricture, urinary-tract infection, and inflammatory diseases of the bladder were excluded. Patients were subjected to UDS followed by VCUG the same day...
March 2014: Urology
René Yiou, Etienne Audureau, Catherine-Marie Loche, Marie Dussaud, Odile Lingombet, Michele Binhas
AIMS: To evaluate pain and embarrassment associated with invasive urodynamics and to determine underlying factors. METHODS: One hundred seventy one consecutive patients referred to our department for invasive urodynamics were evaluated using visual numeric rating scales for sensations of apprehension, pain, and embarrassment during several steps of the procedure (scores ranging from 0 [no symptom] to 10 [worst imaginable symptom]). We also investigated the influence of sex, age, information provided before urodynamics, and medical indication on these sensations...
February 2015: Neurourology and Urodynamics
Zongliang Zhang, Haiyan Qi, Rongxiang Zhou, Xunbo Jin
The present study aimed to report the urodynamic data from 46 male patients who underwent an orthotopic N-shaped neobladder replacement following a radical cystectomy during a 12-month period and to provide urodynamic evidence for the improvement of this technique. A total of 46 consecutive male patients underwent a radical cystectomy and orthotopic N-shaped neobladder substitution due to muscle-invasive bladder cancer. Uroflowmetry, cystometry and urethral pressure profilometry were analyzed at 3-12 months following the surgery...
October 2013: Oncology Letters
Stéphanie Noël, Laurent Massart, Annick Hamaide
BACKGROUND: Vesico-urethral function may be evaluated in humans and dogs by conventional urodynamic testing (cystometry and urethral pressure profilometry) or by electromyography. These techniques are performed under general anaesthesia in dogs. However, anaesthesia can depress bladder and urethral pressures and inhibit the micturition reflex. The primary objective of this pilot study was to evaluate the use of telemetry for urodynamic investigation in dogs. We also aimed to determine the applicability of telemetry to toxicologic studies by assessing the repeatability of telemetric recordings...
2013: BMC Veterinary Research
Vesna S Antovska
INTRODUCTION: Burch colposuspension is a standard treatment for stress urinary incontinence. However, it is associated with recurrence and urinary retention. We describe a modification of this technique to overcome these problems and evaluate the results in comparison with the standard procedure. MATERIALS AND METHODS: A total of 145 patients with isolated stress urinary incontinence (SUI), underwent either our modified pleated colposuspension (PC); n = 97) or standard Burch colposuspension (BC) (n = 48)...
July 2013: Indian Journal of Urology: IJU: Journal of the Urological Society of India
Gerda Trutnovsky, Rodrigo Guzman Rojas, Kristy Pamela Mann, Hans P Dietz
OBJECTIVE: This study aims to explore the effects of menopause and hormone therapy on the symptoms and signs of stress urinary incontinence and urge urinary incontinence. METHODS: Records of women who attended a tertiary urogynecological unit were reviewed retrospectively. A standardized interview included evaluations of symptoms, menopause age (ie, time since last menstrual period or onset of menopausal symptoms), current or previous hormone use, and visual analogue scales for bother...
April 2014: Menopause: the Journal of the North American Menopause Society
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