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https://www.readbyqxmd.com/read/28589463/experimental-and-theoretical-description-of-the-optical-properties-of-myrcia-sylvatica-essential-oil
#1
Andriele da Silva Prado, Luciano Almeida Leal, Patrick Pascoal de Brito, Antonio Luciano de Almeida Fonseca, Stefan Blawid, Artemis Marti Ceschin, Rosa Helena Veras Mourão, Antônio Quaresma da Silva Júnior, Demétrio Antonio da Silva Filho, Luiz Antonio Ribeiro Junior, Wiliam Ferreira da Cunha
We present an extensive study of the optical properties of Myrcia sylvatica essential oil with the goal of investigating the suitability of its material system for uses in organic photovoltaics. The methods of extraction, experimental analysis, and theoretical modeling are described in detail. The precise composition of the oil in our samples is determined via gas chromatography, mass spectrometry, and X-ray scattering techniques. The measurements indicate that, indeed, the material system of Myrcia sylvatica essential oil may be successfully employed for the design of organic photovoltaic devices...
July 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28583301/the-toronto-thromboprophylaxis-patient-safety-initiative-topps-a-cluster-randomised-trial
#2
Artemis Diamantouros, Alex Kiss, Tina Papastavros, David U, Merrick Zwarenstein, William H Geerts
BACKGROUND: Although venous thromboembolism (VTE) is one of the most common and most preventable complications of hospital stay, review of the literature demonstrates large evidence-care gaps for VTE prevention. OBJECTIVES: This study aimed to determine if a multi-component quality improvement (QI) strategy, including the support of hospital leadership, use of order sets, audit and feedback, and active pharmacy involvement, could increase the use of appropriate thromboprophylaxis in patients hospitalized for hip fracture surgery (HFS), major general surgery (MGS) and acute medical illness (MED)...
May 27, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28569992/detective-quantum-efficiency-simulation-of-a-se-imaging-detectors-using-artemis
#3
Yuan Fang, Takaaki Ito, Fumito Nariyuki, Takao Kuwabara, Aldo Badano, Karim S Karim
PURPOSE: This work studies the detective quantum efficiency (DQE) of a-Se-based solid state x-ray detectors for medical imaging applications using ARTEMIS, a Monte Carlo simulation tool for modeling x-ray photon, electron and charged carrier transport in semiconductors with the presence of applied electric field. METHODS: ARTEMIS is used to model the signal formation process in a-Se. The simulation model includes x-ray photon and high-energy electron interactions, and detailed electron-hole pair transport with applied detector bias taking into account drift, diffusion, Coulomb interactions, recombination and trapping...
June 1, 2017: Medical Physics
https://www.readbyqxmd.com/read/28562123/the-role-of-total-body-fat-mass-and-trunk-fat-mass-combined-with-other-endocrine-factors-in-menstrual-recovery-and-psychopathology-of-adolescents-with-anorexia-nervosa
#4
Vasileios Karountzos, Irene Lambrinoudaki, Artemis Tsitsika, Efthimios Deligeoroglou
OBJECTIVE: To determine the threshold of total body and trunk fat mass required for menstrual recovery and to assess the impact of body composition in psychopathology of adolescents with Anorexia Nervosa (AN). METHODS: Prospective study of 60 adolescents presented with secondary amenorrhea and diagnosed with AN. Anthropometrics, body composition by dual-energy X-ray absorptiometry, hormonal studies and responses to mental health screens (EAT-26), were obtained at the beginning and at complete weight restoration, in all adolescents, independently of menstrual recovery (Group A) or not (Group B)...
May 31, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28550350/recent-advances-in-the-study-of-immunodeficiency-and-dna-damage-response
#5
REVIEW
Tomohiro Morio
DNA breaks can be induced by exogenous stimuli or by endogenous stress, but are also generated during recombination of V, D, and J genes (V(D)J recombination), immunoglobulin class switch recombination (CSR). Among various DNA breaks generated, DNA double strand break (DSB) is the most deleterious one. DNA damage response (DDR) is initiated when DSBs are detected, leading to DNA break repair by non-homologous end joining (NHEJ). The process is critically important for the generation of diversity for foreign antigens; and failure to exert DNA repair leads to immunodeficiency such as severe combined immunodeficiency and hyper-IgM syndrome...
May 26, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28548129/central-pathology-review-with-two-stage-quality-assurance-for-pathological-response-after-neoadjuvant-chemotherapy-in-the-artemis-trial
#6
Jeremy St John Thomas, Elena Provenzano, Louise Hiller, Janet Dunn, Clare Blenkinsop, Louise Grybowicz, Anne-Laure Vallier, Ioannis Gounaris, Jean Abraham, Luke Hughes-Davies, Karen McAdam, Stephen Chan, Rizvana Ahmad, Tamas Hickish, Stephen Houston, Daniel Rea, Carlos Caldas, John Ms Bartlett, David Allan Cameron, Richard Laurence Hayward, Helena Margaret Earl
The ARTemis Trial tested standard neoadjuvant chemotherapy±bevacizumab in the treatment of HER2-negative early breast cancer. We compare data from central pathology review with report review and also the reporting behavior of the two central pathologists. Eight hundred women with HER2-negative early invasive breast cancer were recruited. Response to chemotherapy was assessed from local pathology reports for pathological complete response in breast and axillary lymph nodes. Sections from the original core biopsy and surgical excision were centrally reviewed by one of two trial pathologists blinded to the local pathology reports...
May 26, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28531620/compliance-of-pediatric-patients-with-refractory-epilepsy-to-ketogenic-modified-atkins-diet
#7
Sofia Zouganeli, Euaggelia Tasiou, Melpomeni Giorgi, Maria Tsirouda, Artemis Stefanede, Argirios Dinopoulos
No abstract text is available yet for this article.
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28525534/lymphocyte-density-determined-by-computational-pathology-validated-as-a-predictor-of-response-to-neoadjuvant-chemotherapy-in-breast-cancer-secondary-analysis-of-the-artemis-trial
#8
H R Ali, A Dariush, J Thomas, E Provenzano, J Dunn, L Hiller, A-L Vallier, J Abraham, T Piper, J M S Bartlett, D A Cameron, L Hayward, J D Brenton, P D P Pharoah, M Irwin, N A Walton, H M Earl, C Caldas
Background: HASH(0x4ced220) Patients and methods: HASH(0x4784810) Results: HASH(0x569ce98) Conclusions: HASH(0x4cf8070)
May 19, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28520472/a-study-of-the-microbial-spatial-heterogeneity-of-bahamian-thrombolites-using-molecular-biochemical-and-stable-isotope-analyses
#9
Artemis S Louyakis, Jennifer M Mobberley, Brooke E Vitek, Pieter T Visscher, Paul D Hagan, R Pamela Reid, Reinhard Kozdon, Ian J Orland, John W Valley, Noah J Planavsky, Giorgio Casaburi, Jamie S Foster
Thrombolites are buildups of carbonate that exhibit a clotted internal structure formed through the interactions of microbial mats and their environment. Despite recent advances, we are only beginning to understand the microbial and molecular processes associated with their formation. In this study, a spatial profile of the microbial and metabolic diversity of thrombolite-forming mats of Highborne Cay, The Bahamas, was generated by using 16S rRNA gene sequencing and predictive metagenomic analyses. These molecular-based approaches were complemented with microelectrode profiling and in situ stable isotope analysis to examine the dominant taxa and metabolic activities within the thrombolite-forming communities...
May 2017: Astrobiology
https://www.readbyqxmd.com/read/28501587/functional-requirements-for-djla-and-rraa-mediated-enhancement-of-recombinant-membrane-protein-production-in-the-engineered-escherichia-coli-strains-suptoxd-and-suptoxr
#10
Dimitra Gialama, Dafni Chrysanthi Delivoria, Myrsini Michou, Artemis Giannakopoulou, Georgios Skretas
In previous work, we have generated the engineered Escherichia coli strains SuptoxD and SuptoxR, which upon co-expression of the effector genes djlA or rraA, respectively, are capable of suppressing the cytotoxicity caused by membrane protein (MP) overexpression and of producing dramatically enhanced yields for a variety of recombinant MPs of both prokaryotic and eukaryotic origin. Here, we investigated the functional requirements for DnaJ-like protein A (DjlA)- and regulator of ribonuclease activity A (RraA)-mediated enhancement of recombinant MP production in these strains and show that: (i) DjlA and RraA act independently, that is, the beneficial effects of each protein on recombinant MP production occur through a mechanism that does not involve the other, and in a non-additive manner; (ii) full-length and membrane-bound DjlA is required for exerting its beneficial effects on recombinant MP production in E...
May 10, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28486722/lasik-for-the-correction-of-high-hyperopic-astigmatism-with-epithelial-thickness-monitoring
#11
Dan Z Reinstein, Glenn I Carp, Timothy J Archer, Tim Buick, Marine Gobbe, Elizabeth L Rowe, Mario Jukic, Emma Brandon, Johnny Moore, Tara Moore
PURPOSE: To evaluate outcomes of high hyperopic LASIK using the MEL 80 excimer laser (Carl Zeiss Meditec, Jena, Germany). METHODS: Retrospective analysis of 830 consecutive high hyperopic LASIK procedures using the MEL 80 excimer laser and either the VisuMax femtosecond laser (Carl Zeiss Meditec) or zero compression Hansatome microkeratome (Bausch & Lomb, Rochester, NY). Inclusion criteria were attempted hyperopic correction of +4.00 diopters [D] or higher in one axis and corrected distance visual acuity (CDVA) of 20/20 or better...
May 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28459938/disease-free-and-overall-survival-at-3-5-years-for-neoadjuvant-bevacizumab-added-to-docetaxel-followed-by-fluorouracil-epirubicin-and-cyclophosphamide-for-women-with-her2-negative-early-breast-cancer-artemis-trial
#12
H M Earl, L Hiller, J Dunn, C Blenkinsop, L Grybowicz, A-L Vallier, I Gounaris, J Abraham, L Hughes-Davies, K McAdam, S Chan, R Ahmad, T Hickish, D Rea, C Caldas, J M S Bartlett, D A Cameron, E Provenzano, J Thomas, R L Hayward
Background: The ARTemis trial previously reported that addition of neoadjuvant bevacizumab (Bev) to docetaxel followed by fluorouracil, epirubicin and cyclophosphamide (D-FEC) in HER2 negative breast cancer improved the pathological complete response (pCR) rate. We present disease-free (DFS) and overall survival (OS) with central pathology review. Patients and Methods: Patients were randomised to 3 cycles of D followed by 3 cycles of FEC (D-FEC), ± 4 cycles of Bev (Bev+D-FEC)...
April 27, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28440405/copy-number-variation-analysis-in-familial-nonsyndromic-congenital-anomalies-of-the-kidney-and-urinary-tract-evidence-for-the-causative-role-of-a-transposable-element-associated-genomic-rearrangement
#13
Ekaterini Siomou, Artemis G Mitsioni, Vasileios Giapros, Ioanna Bouba, Dimitrios Noutsopoulos, Ioannis Georgiou
Most congenital anomalies of the kidney and urinary tract (CAKUT) are sporadic, but familial occurrence has been described, suggesting a genetic contribution. Copy‑number variations (CNVs) were detected in patients with CAKUT to identify possible novel genomic regions associated with CAKUT. CNVs were investigated in 7 children with CAKUT from three unrelated families using array comparative genomic hybridization: female monozygotic twins with bilateral duplex collecting system/vesicoureteral reflux (VUR)/unilateral renal hypodyspasia (URHD); two male siblings with VUR/URHD; 3 male second cousins, one with bilateral VUR/URHD, one with bilateral VUR and one with ureterovesical junction obstruction (UVJO)...
June 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28436970/unconditioned-unrelated-donor-bone-marrow-transplantation-for-il7r%C3%AE-and-artemis-deficient-scid
#14
C C Dvorak, K Patel, J M Puck, J Wahlstrom, M J Dorsey, R Adams, J Facchino, M J Cowan
No abstract text is available yet for this article.
April 24, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28426205/euro-6-unregulated-pollutant-characterization-and-statistical-analysis-of-after-treatment-device-and-driving-condition-impact-on-recent-passenger-car-emissions
#15
Simon Martinet, Yao Liu, Cédric Louis, Patrick Tassel, Pascal Perret, Agnès Chaumond, Michel André
This study aims to measure and analyze unregulated compound emissions for two Euro 6 diesel and gasoline vehicles. The vehicles were tested on a chassis dynamometer under various driving cycles: Artemis driving cycles (urban, road, and motorway), the New European Driving Cycle (NEDC) and the World Harmonized Light-Duty Test Cycle (WLTC) for Europe, and world approval cycles. The emissions of unregulated compounds (such as total particle number (PN) (over 5.6 nm); black carbon (BC); NO2; benzene, toluene, ethylbenzene, and xylene (BTEX); carbonyl compounds; and polycyclic aromatic hydrocarbons (PAHs)) were measured with several online devices, and different samples were collected using cartridges and quartz filters...
April 28, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28416701/defective-synaptic-connectivity-and-axonal-neuropathology-in-a-human-ipsc-based-model-of-familial-parkinson-s-disease
#16
Georgia Kouroupi, Era Taoufik, Ioannis S Vlachos, Konstantinos Tsioras, Nasia Antoniou, Florentia Papastefanaki, Dafni Chroni-Tzartou, Wolfgang Wrasidlo, Delphine Bohl, Dimitris Stellas, Panagiotis K Politis, Kostas Vekrellis, Dimitra Papadimitriou, Leonidas Stefanis, Piotr Bregestovski, Artemis G Hatzigeorgiou, Eliezer Masliah, Rebecca Matsas
α-Synuclein (αSyn) is the major gene linked to sporadic Parkinson's disease (PD), whereas the G209A (p.A53T) αSyn mutation causes a familial form of PD characterized by early onset and a generally severe phenotype, including nonmotor manifestations. Here we generated de novo induced pluripotent stem cells (iPSCs) from patients harboring the p.A53T mutation and developed a robust model that captures PD pathogenic processes under basal conditions. iPSC-derived mutant neurons displayed novel disease-relevant phenotypes, including protein aggregation, compromised neuritic outgrowth, and contorted or fragmented axons with swollen varicosities containing αSyn and Tau...
May 2, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28409283/body-composition-and-lung-function-in-children-with-cystic-fibrosis-and-meconium-ileus
#17
Artemis Doulgeraki, Argyri Petrocheilou, Glykeria Petrocheilou, George Chrousos, Stavros-Eleftherios Doudounakis, Athanasios G Kaditis
The aim of this study was to explore whether history of meconium ileus (MI) at birth in children and adolescents with cystic fibrosis (CF) adversely affects body composition and lung function in later life. Data of children and adolescents with CF who underwent spirometry and DXA as part of their routine care were analyzed. Associations between MI (explanatory variable) and areal bone mineral density (total body less head-TBLH aBMD), lean tissue mass (LTM), and fat mass (FM) (outcomes) were assessed using general linear models...
April 13, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28407234/mediterranean-diet-decreases-adolescent-waist-circumference
#18
Flora Bacopoulou, Georgios Landis, Anastasios Rentoumis, Artemis Tsitsika, Vasiliki Efthymiou
BACKGROUND: To explore the effects of a multicomponent-multilevel school-based educational intervention on the nutritional habits and abdominal obesity indices of a representative adolescent sample. MATERIALS AND METHODS: A representative sample of 1610 adolescents aged 12-17 years in 23 public high schools of three municipalities in the Attica region in Greece participated in a programme funded by the European Union (August 2013-August 2014). Participants underwent dietary assessment with the use of the Mediterranean Diet Quality Index in children and adolescents (KIDMED), blood pressure (BP) assessment and screening for general and abdominal obesity by measuring body mass index, waist circumference (WC) and waist-to-height ratio (WHtR), at baseline and following a 6-month school-based intervention...
April 13, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28403798/treating-older-hiv-1-infected-subjects-with-cobicistat-boosted-darunavir-in-a-48-week-phase-3-trial
#19
Kimberley Brown, Brooke Patterson-Browning, Chris Liu, Meera Patel, Lisa Stewart, Richard E Nettles
BACKGROUND: An aging HIV-1-infected population warrants examination of the acceptability of individual antiretroviral regimens. In a previous study of ritonavir-boosted darunavir (ARTEMIS), similar safety/efficacy profiles were observed in younger (≤45 years) and older (>45 years) HIV-1-infected subjects. OBJECTIVE: To evaluate safety and efficacy outcomes in HIV-1-infected younger versus older subjects treated with cobicistat-boosted darunavir. METHOD: In a 48-week, phase 3b, open-label trial, HIV-1-infected adults were administered darunavir 800 mg and cobicistat 150 mg once-daily with 2 nucleos(t)ide reverse transcriptase inhibitors (N[t]RTIs)...
April 7, 2017: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/28386247/gamola2-a-comprehensive-software-package-for-the-annotation-and-curation-of-draft-and-complete-microbial-genomes
#20
Eric Altermann, Jingli Lu, Alan McCulloch
Expert curated annotation remains one of the critical steps in achieving a reliable biological relevant annotation. Here we announce the release of GAMOLA2, a user friendly and comprehensive software package to process, annotate and curate draft and complete bacterial, archaeal, and viral genomes. GAMOLA2 represents a wrapping tool to combine gene model determination, functional Blast, COG, Pfam, and TIGRfam analyses with structural predictions including detection of tRNAs, rRNA genes, non-coding RNAs, signal protein cleavage sites, transmembrane helices, CRISPR repeats and vector sequence contaminations...
2017: Frontiers in Microbiology
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