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https://www.readbyqxmd.com/read/29332227/accommodative-esotropia-the-state-of-the-art
#1
REVIEW
Andrea Lembo, Massimiliano Serafino, Marika Dello Strologo, Richard A Saunders, Rupal H Trivedi, Edoardo Villani, Paolo Nucci
PURPOSE: To review the state of the art of Accommodative Esotropia (AE) through careful study of what has been reported up to the point in literature. METHODS: A literature search was done on PubMed using key words including "Accommodative esotropia", "Infantile esotropia", "Strabismus" and "Accommodation". We systematically reviewed and critically appraised what has been written about AE and we tried to analyze that according to the current management of AE. RESULTS: Accommodative Esotropia (AE) is a form of strabismus characterized by convergent misalignment of the visual axes that can be associated with hyperopia and abnormal fusional divergence...
January 13, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29332075/patient-evaluation-and-selection-for-movement-disorders-surgery-the-changing-spectrum-of-indications
#2
Steffen Paschen, Günther Deuschl
This report summarizes the state-of-the-art and controversies around patient selection for deep brain stimulation (DBS) for various conditions. Parkinson's disease (PD): several class I studies have shown superiority of DBS over best medical treatment for advanced PD with fluctuations and further inclusion criteria. One class I study suggests that PD patients with early motor complications might gain more quality of life if operated within 3 years after the onset of fluctuations. The subthalamic nucleus (STN) is still the standard target...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29331972/cohort-profile-the-comparative-outcomes-and-service-utilization-trends-coast-study-among-people-living-with-and-without-hiv-in-british-columbia-canada
#3
Oghenowede Eyawo, Mark W Hull, Kate Salters, Hasina Samji, Angela Cescon, Paul Sereda, Viviane D Lima, Bohdan Nosyk, David G T Whitehurst, Scott A Lear, Julio S G Montaner, Robert S Hogg
PURPOSE: The Comparative Outcomes And Service Utilization Trends (COAST) Study in British Columbia (BC), Canada, was designed to evaluate the determinants of health outcomes and health care services use among people living with HIV (PLHIV) as they age in the period following the introduction of combination antiretroviral therapy (cART). The study also assesses how age-associated comorbidities and health care use among PLHIV may differ from those observed in the general population. PARTICIPANTS: COAST was established through a data linkage between two provincial data sources: The BC Centre for Excellence in HIV/AIDS Drug Treatment Program, which centrally manages cART dispensation across BC and contains prospectively collected data on demographic, immunological, virological, cART use and other clinical information for all known PLHIV in BC; and Population Data BC, a provincial data repository that holds individual event-level, longitudinal data for all 4...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29331424/ultra-narrow-surface-lattice-resonances-in-plasmonic-metamaterial-arrays-for-biosensing-applications
#4
Artem Danilov, Gleb Tselikov, Fan Wu, Vasyl G Kravets, Igor Ozerov, Frederic Bedu, Alexander N Grigorenko, Andrei V Kabashin
When excited over a periodic metamaterial lattice of gold nanoparticles (~ 100nm), localized plasmon resonances (LPR) can be coupled by a diffraction wave propagating along the array plane, which leads to a drastic narrowing of plasmon resonance lineshapes (down to a few nm full-width-at-half-maximum) and the generation of singularities of phase of reflected light. These phenomena look very promising for the improvement of performance of plasmonic biosensors, but conditions of implementation of such diffractively coupled plasmonic resonances, also referred to as plasmonic surface lattice resonances (PSLR), are not always compatible with biosensing arrangement implying the placement of the nanoparticles between a glass substrate and a sample medium (air, water)...
December 9, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29331117/accurate-virial-coefficients-of-gaseous-krypton-from-state-of-the-art-ab-initio-potential-and-polarizability-of-the-krypton-dimer
#5
Bo Song, Jonathan M Waldrop, Xiaopo Wang, Konrad Patkowski
We have developed a new krypton-krypton interaction-induced isotropic dipole polarizability curve based on high-level ab initio methods. The determination was carried out using the coupled-cluster singles and doubles plus perturbative triples method with very large basis sets up to augmented correlation-consistent sextuple zeta as well as the corrections for core-core and core-valence correlation and relativistic effects. The analytical function of polarizability and our recently constructed reference interatomic potential [J...
January 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29331102/opposite-sex-relationship-questionnaire-for-female-adolescents-development-and-psychometric-evolution
#6
Masoumeh Sibmar, Nasim Bahrami, AbouAli Vedadhir, Hamid Alavi Majd, Averil Parker
Aim The goal of the present study is to adopt state-of-the-art techniques and standards to develop and evaluate a measure, called the opposite-sex relationship questionnaire for female adolescents (OSRQFA), to assess the reasons why adolescent girls would or would not develop, a relationship with an adolescent boy. Methods A mixed-method, sequential, exploratory design was adopted. In the qualitative phase, an in-depth interview approach was used to identify the properties and dimensions to be included in the OSRQFA...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29331065/component-resolved-diagnostics-to-direct-in-venom-immunotherapy-important-steps-towards-precision-medicine
#7
Simon Blank, Maria Beatrice Bilò, Markus Ollert
Stings of Hymenoptera can induce IgE-mediated systemic and even fatal allergic reactions. Venom-specific immunotherapy (VIT) is the only disease-modifying and curative treatment of venom allergy. However, choosing the correct venom for VIT represents a necessary prerequisite for efficient protection against further anaphylactic sting reactions after VIT. In the past, therapeutic decisions based on the measurement of specific IgE (sIgE) levels to whole venom extracts were not always straightforward, especially when the patient was not able to identify the culprit insect...
January 13, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29330506/impact-of-wave-whitecapping-on-land-falling-tropical-cyclones
#8
Nicolas Bruneau, Ralf Toumi, Shuai Wang
Predicting tropical cyclone structure and evolution remains challenging. Particularly, the surface wave interactions with the continental shelf and their impact on tropical cyclones have received very little attention. Through a series of state-of-the-art high-resolution, fully-coupled ocean-wave and atmosphere-ocean-wave experiments, we show here, for the first time, that in presence of continental shelf waves can cause substantial cooling of the sea surface. Through whitecapping there is a transfer of momentum from the surface which drives deeper vertical mixing...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330495/large-unexplained-suite-of-chemically-reactive-compounds-present-in-ambient-air-due-to-biomass-fires
#9
V Kumar, B P Chandra, V Sinha
Biomass fires impact global atmospheric chemistry. The reactive compounds emitted and formed due to biomass fires drive ozone and organic aerosol formation, affecting both air quality and climate. Direct hydroxyl (OH) Reactivity measurements quantify total gaseous reactive pollutant loadings and comparison with measured compounds yields the fraction of unmeasured compounds. Here, we quantified the magnitude and composition of total OH reactivity in the north-west Indo-Gangetic Plain. More than 120% increase occurred in total OH reactivity (28 s-1 to 64 s-1) and from no missing OH reactivity in the normal summertime air, the missing OH reactivity fraction increased to ~40 % in the post-harvest summertime period influenced by large scale biomass fires highlighting presence of unmeasured compounds...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329940/cardiovascular-risk-reduction-in-persons-living-with-hiv-treatment-development-feasibility-and-preliminary-results
#10
Patricia A Cioe, Kate M Guthrie, Matthew S Freiberg, David M Williams, Christopher W Kahler
Persons living with HIV (PLWH) have elevated risks for cardiovascular disease (CVD). Our goal was to develop and pilot test a tailored intervention to improve CVD risk perception and the adoption of heart-healthy behaviors. In-depth qualitative interviews were conducted with 30 PLWH participants to examine learning needs and preferences. An intervention manual was developed and tested in an open pilot with eight participants. Participants were stable on antiretroviral therapy and were recruited from two urban HIV clinics in the northeastern United States...
December 5, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29329701/automatic-information-extraction-from-unstructured-mammography-reports-using-distributed-semantics
#11
Anupama Gupta, Imon Banerjee, Daniel L Rubin
To date, the methods developed for automated extraction of information from radiology reports are mainly rule-based or dictionary-based, and, therefore, require substantial manual effort to build these systems. Recent efforts to develop automated systems for entity detection have been undertaken, but little work has been done to automatically extract relations and their associated named entities in narrative radiology reports that have comparable accuracy to rule-based methods. Our goal is to extract relations in a unsupervised way from radiology reports without specifying prior domain knowledge...
January 9, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29329666/advances-in-self-healing-materials-based-on-vascular-networks-with-mechanical-self-repair-characteristics
#12
REVIEW
Min Wook Lee, Seongpil An, Sam S Yoon, Alexander L Yarin
Here, we review the state-of-the-art in the field of engineered self-healing materials. These materials mimic the functionalities of various natural materials found in the human body (e.g., the healing of skin and bones by the vascular system). The fabrication methods used to produce these "vascular-system-like" engineered self-healing materials, such as electrospinning (including co-electrospinning and emulsion spinning) and solution blowing (including coaxial solution blowing and emulsion blowing) are discussed in detail...
December 24, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/29329522/a-game-improving-the-assembly-of-pooled-functional-metagenomics-sequence-data
#13
Matteo Chiara, Antonio Placido, Ernesto Picardi, Luigi Ruggiero Ceci, David Stephen Horner, Graziano Pesole
BACKGROUND: Expression screening of environmental DNA (eDNA) libraries is a popular approach for the identification and characterization of novel microbial enzymes with promising biotechnological properties. In such "functional metagenomics" experiments, inserts, selected on the basis of activity assays, are sequenced with high throughput sequencing technologies. Assembly is followed by gene prediction, annotation and identification of candidate genes that are subsequently evaluated for biotechnological applications...
January 12, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29329398/lenup-learning-nucleosome-positioning-from-dna-sequences-with-improved-convolutional-neural-networks
#14
Juhua Zhang, Wenbo Peng, Lei Wang
Motivation: Nucleosome positioning plays significant roles in proper genome packing and its accessibility to execute transcription regulation. Despite a multitude of nucleosome positioning resources available on line including experimental datasets of genome-wide nucleosome occupancy profiles and computational tools to the analysis on these data, the complex language of eukaryotic Nucleosome positioning remains incompletely understood. Results: Here, we address this challenge using an approach based on a state-of-the-art machine learning method...
January 10, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29329294/a-two-stage-flow-based-intrusion-detection-model-for-next-generation-networks
#15
Muhammad Fahad Umer, Muhammad Sher, Yaxin Bi
The next-generation network provides state-of-the-art access-independent services over converged mobile and fixed networks. Security in the converged network environment is a major challenge. Traditional packet and protocol-based intrusion detection techniques cannot be used in next-generation networks due to slow throughput, low accuracy and their inability to inspect encrypted payload. An alternative solution for protection of next-generation networks is to use network flow records for detection of malicious activity in the network traffic...
2018: PloS One
https://www.readbyqxmd.com/read/29329268/anomaly-detection-in-nanofibrous-materials-by-cnn-based-self-similarity
#16
Paolo Napoletano, Flavio Piccoli, Raimondo Schettini
Automatic detection and localization of anomalies in nanofibrous materials help to reduce the cost of the production process and the time of the post-production visual inspection process. Amongst all the monitoring methods, those exploiting Scanning Electron Microscope (SEM) imaging are the most effective. In this paper, we propose a region-based method for the detection and localization of anomalies in SEM images, based on Convolutional Neural Networks (CNNs) and self-similarity. The method evaluates the degree of abnormality of each subregion of an image under consideration by computing a CNN-based visual similarity with respect to a dictionary of anomaly-free subregions belonging to a training set...
January 12, 2018: Sensors
https://www.readbyqxmd.com/read/29329265/multiple-octave-spanning-vibration-sensing-based-on-simultaneous-vector-demodulation-of-499-fizeau-interference-signals-from-identical-ultra-weak-fiber-bragg-gratings-over-2-5-km
#17
Yi Li, Li Qian, Ciming Zhou, Dian Fan, Qiannan Xu, Yandong Pang, Xi Chen, Jianguan Tang
Multi-point vibration sensing at the low frequency range of 0.5-100 Hz is of vital importance for applications such as seismic monitoring and underwater acoustic imaging. Location-resolved multi-point sensing using a single fiber and a single demodulation system can greatly reduce system deployment and maintenance costs. We propose and demonstrate the demodulation of a fiber-optic system consisting of 500 identical ultra-weak Fiber Bragg gratings (uwFBGs), capable of measuring the amplitude, frequency and phase of acoustic signals from 499 sensing fibers covering a total range of 2...
January 12, 2018: Sensors
https://www.readbyqxmd.com/read/29329264/engineering-ru-pt-core-shell-catalysts-for-enhanced-electrochemical-oxygen-reduction-mass-activity-and-stability
#18
Ariel Jackson, Alaina Strickler, Drew Higgins, Thomas Francisco Jaramillo
Improving the performance of oxygen reduction reaction (ORR) electrocatalysts is essential for the commercial efficacy of many renewable energy technologies, including low temperature polymer electrolyte fuel cells (PEFCs). Herein, we report highly active and stable carbon-supported Ru@Pt core-shell nanoparticles (Ru@Pt/C) prepared by a wet chemical synthesis technique. Through rotating disc electrode testing, the Ru@Pt/C achieves an ORR Pt mass-based activity of 0.50 A mgPt-1 at 0.9 V versus the reversible hydrogen electrode (RHE), which exceeds the activity of the state-of-the-art commercial Pt/C catalyst as well as the Department of Energy 2020 PEFC electrocatalyst activity targets for transportation applications...
January 12, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29328962/so-you-think-computational-approaches-to-understanding-glycosaminoglycan-protein-interactions-are-too-dry-and-too-rigid-think-again
#19
REVIEW
Nehru Viji Sankaranarayanan, Balaji Nagarajan, Umesh R Desai
Glycosaminoglycans (GAGs) play key roles in virtually all biologic responses through their interaction with proteins. A major challenge in understanding these roles is their massive structural complexity. Computational approaches are extremely useful in navigating this bottleneck and, in some cases, the only avenue to gain comprehensive insight. We discuss the state-of-the-art on computational approaches and present a flowchart to help answer most basic, and some advanced, questions on GAG-protein interactions...
January 9, 2018: Current Opinion in Structural Biology
https://www.readbyqxmd.com/read/29328646/vibrational-properties-of-bulk-boric-acid-2a-and-3t-polymorphs-and-their-two-dimensional-layers-measurements-and-density-functional-theory-calculations
#20
Mauricelio Bezerra da Silva, Regina C R Santos, Paulo T C Freire, Ewerton W S Caetano, Valder N Freire
Boric acid (H3BO3) is being used effectively nowadays in traps/baits for the management of Aedes aegypti L. and Aedes albopictus Skuse species of mosquitoes, which are the main spreading vectors worldwide for diseases like malaria, dengue and zika. Previously, we have published results on the structural, electronic and optical properties of its molecular triclinic H3BO3-2A and trigonal H3BO3-3T polymorphs within the framework of density functional theory (DFT). Due to the renewed importance of these materials, the focus of this work is on the vibrational properties of the bulk boric acid 2A and 3T polymorphs...
January 12, 2018: Journal of Physical Chemistry. A
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