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Pulsed dye laser

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https://www.readbyqxmd.com/read/28425593/medium-sized-nevus-spilus-of-the-neck-treated-with-pulsed-dye-laser
#1
Vito Abrusci, Valentina Benzecry
Patients with large benign melanocytic lesions located on the neck represent a therapeutic challenge since the neck is a high-risk area for hypertrophic scarring and/or retraction. When treating a benign, extensive and visible melanocytic lesion, the choice of therapy mainly depends on the likelihood of improved cosmesis. We report a case of a 33-year-old woman with a medium-sized Nevus Spilus located on the neck, successfully treated with four sessions of pulsed dye laser. We achieved an excellent clinical and cosmetic result in such a challenging area...
April 20, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28413806/ryanodine-and-ip3-receptor-mediated-calcium-signaling-play-a-pivotal-role-in-neurological-infrared-laser-modulation
#2
Gleb P Tolstykh, Cory A Olsovsky, Bennett L Ibey, Hope T Beier
Pulsed infrared (IR) laser energy has been shown to modulate neurological activity through both stimulation and inhibition of action potentials. While the mechanism(s) behind this phenomenon is (are) not completely understood, certain hypotheses suggest that the rise in temperature from IR exposure could activate temperature- or pressure-sensitive ion channels or create pores in the cellular outer membrane, allowing an influx of typically plasma-membrane-impermeant ions. Studies using fluorescent intensity-based calcium ion ([Formula: see text]) sensitive dyes show changes in [Formula: see text] levels after various IR stimulation parameters, which suggests that [Formula: see text] may originate from the external solution...
April 2017: Neurophotonics
https://www.readbyqxmd.com/read/28403266/laser-assisted-photodynamic-therapy-two-novel-protocols-for-enhanced-treatment-results
#3
Mary L Stevenson, Julie K Karen, Elizabeth K Hale
<p>Photodynamic therapy (PDT) uses a topical photosensitizing agent which is activated by a light source to cause destruction of specific cells. Commonly used for the treatment of actinic keratoses and photodamage, PDT can also be used for other conditions including acne and sebaceous hyperplasia. Here we report our experience with two treatment protocols. The first protocol utilizes laser assisted delivery of topical 5-aminolevulinic acid for enhanced efficacy of blue light photodynamic therapy in the treatment of actinic keratoses and photodamage...
April 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28401413/concentration-dependent-approach-for-accurate-determination-of-two-photon-absorption-cross-section-of-fluorescent-dye-molecule
#4
Sandeep Kumar Maurya, Chayan Dutta, Debabrata Goswami
We have investigated the concentration dependent of two-photon induced fluorescence (TPIF) in methanolic solution of Rhodamine 6G and Rhodamine B dye using 120 fs laser pulses at 780 nm, 76 MHz repetition rate. TPIF study of these dyes was compared with their respective one photon fluorescence intensity. We have shown the effect of chopper on TPIF intensity from Rhodamine dyes, which have shown direct influence on the determined TPA Cross section of these dyes.
April 11, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28388282/combined-pulsed-dye-laser-and-fiberoptic-nd-yag-laser-for-the-treatment-of-hypertrophic-port-wine-stain
#5
Mohammed Radmanesh, Ramin Radmanesh
The hypertrophic port wine stain (PWS) is only partially and superficially treated with the Pulsed dye laser(PDL) because of its limited depth of penetration. We used combined PDL and fiberoptic 1444nm Nd-YAG laser to treat a case with hypertrophic PWS. METHOD: After tumescent anesthesia, few holes were made by a 16 gauge needle on different sides of the lesion. The fiberoptic tip was of 1444nm Nd-YAG laser was inserted within the holes and was pushed forward while triggering. In a fan pattern and by a back and forth movement, the subcutaneous and deep dermal areas were coagulated...
April 7, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28375972/striae-distensae-preventative-and-therapeutic-modalities-to-improve-aesthetic-appearance
#6
Nicholas A Ross, Derek Ho, Juliya Fisher, Andrew Mamalis, Edward Heilman, Nazanin Saedi, Jared Jagdeo
BACKGROUND: Striae distensae (SD) are aesthetically troublesome to patients and therapeutically challenging. OBJECTIVE: Herein, the authors comprehensively review the literature pertaining to the history, pathogenesis, clinical presentation, clinical rating scales, and laboratory, imaging, and histologic features of SD. METHODS AND MATERIALS: A review of PubMed, MEDLINE, Scopus, Embase, and Google scholar was conducted, including literature published from 1773 to August 6, 2016...
April 3, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28374298/peri-procedure-laser-scar-therapy-protocol-a-pilot-survey-of-plastic-surgeons-practices
#7
Michael Mirmanesh, Zachary Borab, Madeleine Gantz, Pirko Maguina
BACKGROUND: Scar management using laser phototherapy continues to evolve as it gains wide acceptance among patients and providers. Despite widespread use of laser therapy, there are no guidelines or consensus published regarding optimal pre- and post-procedure patient management. Our objective is to gain insight into the best laser practices; we decided to poll colleagues nationwide. METHODS: An online survey was distributed to members of the American Society of Plastic Surgeons...
April 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28358185/lasers-in-the-treatment-of-acne
#8
Marina Perper, John Tsatalis, Ariel E Eber, Jessica Cervantes, Keyvan Nouri
Acne is a chronic disease of the pilosebaceous units, presenting as inflammatory or noninflammatory lesions, affecting primarily the face but also the back and chest. The mainstay of treatment remains topical retinoids, benzoyl peroxide, azelaic acid, antibiotics, and isotretinoin, many of which result in poor compliance, lack of durable remission, and incur adverse effects. The use of lasers to treat acne is continuously increasing because of their minimal complications, limited number of office-based treatments required, potential benefits of simultaneously treating acne scarring, and the rapid onset of results...
March 28, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28338214/light-therapies-for-acne-abridged-cochrane-systematic-review-including-grade-assessments
#9
REVIEW
J Barbaric, R Abbott, P Posadzki, M Car, L H Gunn, A M Layton, A Majeed, J Car
We undertook a Cochrane review of randomized controlled trials (RCTs) evaluating the effects of light-based interventions for acne vulgaris. We searched the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, LILACS, ISI Web of Science, and grey literature sources (September 2015). We used the Grading of Recommendations Assessment, Development and Evaluation Working Group approach to assess the quality of evidence (QE). We included 71 RCTs (4211 participants, median sample size 31). Results from a single study (n = 266, low QE) showed little or no difference in effectiveness on participants' assessment of improvement between 20% aminolevulinic acid (ALA) photodynamic therapy (PDT), activated by blue light, versus vehicle plus blue light, whereas another study (n = 180) of a comparison of ALA-PDT (red light) concentrations showed 20% ALA-PDT was no more effective than 15%, but better than 10% and 5% ALA-PDT...
March 24, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28285560/prospective-pilot-study-on-combined-use-of-pulsed-dye-laser-and-1-topical-rapamycin-for-treatment-of-non-facial-cutaneous-capillary-malformation
#10
Eun Jin Doh, Jungyoon Ohn, Min Ji Kim, Young Gull Kim, Soyun Cho
BACKGROUND: The regeneration or revascularization of blood vessels after pulsed dye laser (PDL) treatment is one of the causes of treatment failures of cutaneous capillary malformations (CM). Recently, topical administration of rapamycin was introduced as a possible adjunctive therapeutic option to minimize post-laser revascularization in facial CM. OBJECTIVES: We evaluated the effect of combined use of 1% topical rapamycin with PDL compared to PDL alone in cutaneous CM of trunk or extremities and tried to identify the optimal duration of topical rapamycin application...
March 13, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28274357/laser-and-light-based-treatments-of-acne-and-acne-scarring
#11
Macrene Alexiades
The treatment of acne and acne scarring with lasers and light-based and energy-based technologies has become an integral component of our therapeutic arsenal. Lasers including infrared wavelengths and pulsed dye lasers; light devices including blue light, red light, and broadband light; and photodynamic therapy with aminolevulinic acid and methylaminolevulinic acid have been shown to be effective in the treatment of acne vulgaris. The optimal outcomes are achieved with photodynamic therapy combined with medical therapy...
March 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28272080/pulsed-dye-laser-therapy-in-the-treatment-of-warts-a-review-of-the-literature
#12
David Veitch, Georgios Kravvas, Firas Al-Niaimi
BACKGROUND: Warts or verrucae vulgaris are common cutaneous infections with currently no definitive curative treatments available. OBJECTIVE: To determine the efficacy of pulsed dye laser (PDL) in the treatment of warts. MATERIALS AND METHODS: A literature search was performed using the PubMed and MEDLINE databases. A search using {(Wart[s], verruca or condylomata)} AND [(Pulsed dye laser)] was used. Forty-four articles were identified as relevant to this review...
April 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28213832/dynamic-fluorescence-microscopy-of-cellular-uptake-of-intercalating-model-drugs-by-ultrasound-activated-microbubbles
#13
B H A Lammertink, R Deckers, M Derieppe, I De Cock, I Lentacker, G Storm, C T W Moonen, C Bos
PURPOSE: The combination of ultrasound and microbubbles can facilitate cellular uptake of (model) drugs via transient permeabilization of the cell membrane. By using fluorescent molecules, this process can be studied conveniently with confocal fluorescence microscopy. This study aimed to investigate the relation between cellular uptake and fluorescence intensity increase of intercalating model drugs. PROCEDURES: SYTOX Green, an intercalating fluorescent dye that displays >500-fold fluorescence enhancement upon binding to nucleic acids, was used as a model drug for ultrasound-induced cellular uptake...
February 17, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28192297/controlling-and-tracking-of-colloidal-nanostructures-through-two-photon-fluorescence
#14
Dipankar Mondal, Debabrata Goswami
Multiphoton absorbing dye-coated trapped spherical bead at the focal plane of femtosecond optical tweezers shows nonlinear optical (NLO) phenomena. One such NLO process of two-photon fluorescence (TPF) has been used for the background-free imaging of a femtosecond laser-trapping event. Due to the high peak powers of femtosecond laser pulses with low average powers, it is possible to not only trap single nanospheres, but encourage optically directed self-assembly. The TPF signatures of trapped particles show evidence of such a directed self-assembly process which, in turn, can provide information about the structural dynamics during the process of cluster formation...
October 7, 2016: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28191657/prospective-open-label-rater-blinded-and-self-controlled-pilot-study-of-the-treatment-of-proliferating-superficial-infantile-hemangiomas-with-0-5-topical-timolol-cream-versus-595-nm-pulsed-dye-laser
#15
Hanru Ying, Yun Zou, Wenxin Yu, Yajing Qiu, Gang Ma, Lei Chang, Yifei Gu, Dongze Lyu, Xiaoxi Lin
Topical timolol and 595-nm pulsed dye laser (PDL) are both widely used in the treatment of superficial infantile hemangiomas (IH). However, to date, there is no reliable study comparing the therapeutic outcomes between the two treatment options. We designed the present study to evaluate and compare the efficacy and safety of timolol cream and PDL in the treatment of superficial proliferating IH. Twenty-one patients with superficial IH were included in the study. Each lesion was divided into two regions; one part was treated with 0...
February 13, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28181222/systematic-review-of-laser-therapy-in-xanthelasma-palpebrarum
#16
REVIEW
Austin H Nguyen, Adam M Vaudreuil, Christopher J Huerter
Xanthelasma palpebrarum is a benign periorbital xanthoma with substantial cosmetic and psychosocial burden for patients. Treatment modalities should be considered based on efficacy as well as cosmetic outcome. Laser modalities in the treatment of xanthelasma palpebrarum have not been comprehensively reviewed and discussed. Accordingly, this study seeks to systematically and critically review the available literature discussing laser treatment of xanthelasma palpebrarum. PubMed was systematically reviewed for reports on laser therapy in the treatment of xanthelasma palpebrarum...
March 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28166093/cutaneous-involvement-in-adult-multisystemic-langerhans-cell-histiocytosis-successfully-treated-with-pulsed-dye-laser
#17
Ximena Calderón-Castrat, Monica Roncero-Riesco, María T Alonso-San Pablo, Ángel Santos-Briz, Emilia Fernández-López
No abstract text is available yet for this article.
February 3, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28134994/retrospective-analysis-of-the-treatment-of-melasma-lesions-exhibiting-increased-vascularity-with-the-595-nm-pulsed-dye-laser-combined-with-the-1927-nm-fractional-low-powered-diode-laser
#18
REVIEW
Elizabeth R C Geddes, Ashlyn B Stout, Paul M Friedman
BACKGROUND: Melasma presents a significant challenge to laser surgeons. Aggressive treatments often result in rebound melasma or post-inflammatory pigmentary alteration. Recent reports suggest melasma pathogenesis may have a vascular component. Spectrocolorimetry can detect subtle or sub-clinical telangiectatic erythema within melasma lesions. For certain patients identified by spectrocolorimetry, effective melasma treatment may include vascular-targeted therapy together with pigment-specific treatment modalities...
January 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28118926/treatment-of-nail-psoriasis-with-pulse-dye-laser-plus-calcipotriol-betametasona-gel-vs-nd-yag-plus-calcipotriol-betamethasone-gel-an-intrapatient-left-to-right-controlled-study
#19
L C Arango-Duque, M Roncero-Riesco, T Usero Bárcena, I Palacios Álvarez, E Fernández López
BACKGROUND: Treatment of nail psoriasis remains a challenging and often disappointing situation. OBJECTIVE: To compare the efficacy, adverse reactions and tolerability of treatment of nail psoriasis with PDL vs. Nd:YAG, in association with betametasona calcipotriol gel. METHODS: An open, prospective intrapatient left-to-right study was designed. The right hand of each patient received treatment with PDL and the left hand with Nd:YAG. Betamethasone calcipotriol gel was applied once a day during the first week after each laser session...
January 21, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28095541/safety-and-efficacy-evaluation-of-pulsed-dye-laser-treatment-co-sub-2-sub-ablative-fractional-resurfacing-and-combined-treatment-for-surgical-scar-clearance
#20
Joel L Cohen, Roy Geronemus
BACKGROUND & OBJECTIVE: Surgical scars are an unwanted sequela following surgical procedures. Several different treatment modalities and approaches are currently being employed to improve the cosmesis of surgical scars with each having varying degrees of success. The objective of this study was to assess the ef cacy and safety pulsed dye laser treatment, CO2 ablative fractional resurfacing, and a combined treatment with these two modalities for the cosmetic improvement of surgical scarring that occurred following the surgical removal of skin cancer from different anatomic areas...
November 1, 2016: Journal of Drugs in Dermatology: JDD
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