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https://www.readbyqxmd.com/read/28845551/management-of-side-effects-during-and-post-treatment-in-breast-cancer-survivors
#1
Oxana Palesh, Caroline Scheiber, Shelli Kesler, Karen Mustian, Cheryl Koopman, Lidia Schapira
Cancer-related fatigue, insomnia, and cancer-related cognitive impairment are commonly experienced symptoms that share psychological and physical manifestations. One or more of these symptoms will affect nearly all patients at some point during their course of treatment or survivorship. These side effects are burdensome and reduce patients' quality of life well beyond their cancer diagnosis and associated care treatments. Cancer-related fatigue, insomnia, and cancer-related cognitive impairment are likely to have multiple etiologies that make it difficult to identify the most effective method to manage them...
August 27, 2017: Breast Journal
https://www.readbyqxmd.com/read/28836379/home-based-multidimensional-survivorship-programmes-for-breast-cancer-survivors
#2
REVIEW
Karis Kin Fong Cheng, Yee Ting Ethel Lim, Zhi Min Koh, Wilson Wai San Tam
BACKGROUND: The prognosis and survival rate of women with breast cancer have significantly improved worldwide. Effective home-based multidimensional programmes for breast cancer survivors have gained an ever greater emphasis in survivorship care to maximise women's quality of life for their successful transition to rehabilitation and normal life. It is important to summarise the best available evidence to evaluate the effects of home-based multidimensional survivorship programmes on quality of life in women within 10 years of the completion of surgery or adjuvant cancer therapy for breast cancer, or both...
August 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28832427/resistance-training-reduces-inflammation-and-fatigue-and-improves-physical-function-in-older-breast-cancer-survivors
#3
Monica C Serra, Alice S Ryan, Heidi K Ortmeyer, Odessa Addison, Andrew P Goldberg
OBJECTIVE: Resistance training (RT) reduces fatigue and improves physical function and quality of life (QOL) in breast cancer survivors (BCS). This may be related to reductions in systemic and tissue-specific inflammation. This pilot study examines the hypothesis that RT induces changes in systemic and tissue-specific inflammation that contribute to improvements in physical and behavioral function in postmenopausal BCS. METHODS: Eleven BCS (60 ± 2 years old, body mass index 30 ± 1 kg/m, mean ± SEM) underwent assessments of fatigue (Piper Fatigue Scale), physical function, QOL (SF-36), glucose and lipid metabolism, and systemic, skeletal muscle, and adipose tissue inflammation (n = 9) before and after 16 weeks of moderate-intensity whole-body RT...
August 21, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28690587/brain-connectivity-patterns-dissociate-action-of-specific-acupressure-treatments-in-fatigued-breast-cancer-survivors
#4
Richard E Harris, Eric Ichesco, Chelsea Cummiford, Johnson P Hampson, Thomas L Chenevert, Neil Basu, Suzanna M Zick
Persistent fatigue is a pernicious symptom in many cancer survivors. Existing treatments are limited or ineffective and often lack any underlying biologic rationale. Acupressure is emerging as a promising new intervention for persistent cancer-related fatigue; however, the underlying mechanisms of action are unknown. Our previous investigations suggested that fatigued breast cancer survivors have alterations in brain neurochemistry within the posterior insula and disturbed functional connectivity to the default mode network (DMN), as compared to non-fatigued breast cancer survivors...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28677009/the-effects-of-physical-activity-and-fatigue-on-cognitive-performance-in-breast-cancer-survivors
#5
Diane K Ehlers, Susan Aguiñaga, Josh Cosman, Joan Severson, Arthur F Kramer, Edward McAuley
PURPOSE: Research suggests that physical activity may be a promising treatment for cancer-related cognitive impairment; however, evidence is limited by small samples and self-report measures and little is known about the underlying mechanisms. The purpose of this study was to examine the effects of physical activity on cognitive function in a national sample of breast cancer survivors (BCSs) using objective measures. We hypothesized that physical activity's effects on cognition would be indirect through survivors' self-reported fatigue...
July 4, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28666465/the-association-between-physical-activity-and-health-related-quality-of-life-among-breast-cancer-survivors
#6
Woo-Kyoung Shin, Sihan Song, So-Youn Jung, Eunsook Lee, Zisun Kim, Hyeong-Gon Moon, Dong-Young Noh, Jung Eun Lee
BACKGROUND: The quality of life for breast cancer survivors has become increasingly important because of their high survival rate and prolonged life expectancy. The purpose of this study was to examine the association of physical activity following diagnosis and health-related quality of life (HRQOL) in breast cancer survivors. METHODS: We conducted a cross-sectional study of breast cancer survivors. A total of 231 women aged 21-78 years who had been diagnosed with stages I to III breast cancer and had breast cancer surgery at least 6 months prior were recruited from three hospitals between September 2012 and April 2015 and were included in this study...
June 30, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28665541/feasibility-of-the-mobile-mindfulness-based-stress-reduction-for-breast-cancer-mmbsr-bc-program-for-symptom-improvement-among-breast-cancer-survivors
#7
Cecile A Lengacher, Richard R Reich, Sophia Ramesar, Carissa B Alinat, Manolete Moscoso, Lakeshia Cousin, Victoria R Marino, Maya N Elias, Carly L Paterson, Carmen S Rodriguez, Hsiao-Lan Wang, Kevin E Kip, Hongdao Meng, Jong Y Park
OBJECTIVE: The purpose of this pilot study was to test the feasibility of delivering the mobile Mindfulness-Based Stress Reduction for Breast Cancer (mMBSR(BC)) program using an iPad and to evaluate its impact on symptom improvement. METHODS: A single group, pre-posttest design was implemented among female stages 0-III breast cancer survivors (BCS) who completed treatment. Data were collected at baseline and week 6 on measures of psychological and physical symptoms and quality of life...
June 30, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28636526/does-health-coaching-grow-capacity-in-cancer-survivors-a-systematic-review
#8
Suzette Barakat, Kasey Boehmer, Marwan Abdelrahim, Sangwoo Ahn, Abdulrahman A Al-Khateeb, Neri Álvarez Villalobos, Larry Prokop, Patricia J Erwin, Kirsten Fleming, Valentina Serrano, Gabriela Spencer-Bonilla, Mohammad Hassan Murad
Interventions that grow patient capacity to do the work of health care and life are needed to support the health of cancer survivors. Health coaching may grow capacity. This systematic review of health coaching interventions explored coaching's ability to grow capacity of cancer survivors. The authors included randomized trials or quasi-experimental studies comparing coaching to alternative interventions, and adhered to PRISMA reporting guidelines. Data were analyzed using the Theory of Patient Capacity (BREWS: Capacity is affected by factors that influence ability to reframe Biography ["B"], mobilize or recruit Resources ["R"], interact with the Environment of care ["E"], accomplish Work ["W"]), and function Socially ["S"])...
June 21, 2017: Population Health Management
https://www.readbyqxmd.com/read/28624715/impact-of-physical-activity-in-group-versus-individual-physical-activity-on-fatigue-in-patients-with-breast-cancer-a-pilot-study
#9
Christine Desbiens, Myriam Filion, Marie-Chantale Brien, Jean-Charles Hogue, Christian Laflamme, Julie Lemieux
BACKGROUND: Physical activity improves the quality of life of cancer survivors, but whether there is a difference between individual vs. group physical activity is unknown. OBJECTIVES: To compare fatigue at 12 weeks in breast cancer survivors after participation in a program of group vs. individual video-assisted physical activity. METHODS: This was a randomized phase II pilot study carried out in breast cancer survivors at a tertiary breast cancer center...
June 15, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28621820/the-efficacy-of-internet-based-cognitive-behavioral-therapy-for-severely-fatigued-survivors-of-breast-cancer-compared-with-care-as-usual-a-randomized-controlled-trial
#10
Harriët J G Abrahams, Marieke F M Gielissen, Rogier R T Donders, Martine M Goedendorp, Agnes J van der Wouw, Constans A H H V M Verhagen, Hans Knoop
BACKGROUND: Severe fatigue is a common and distressing symptom affecting approximately one in four survivors of breast cancer. The current study examined the efficacy of Internet-based cognitive behavioral therapy (ICBT) for severe fatigue in survivors of breast cancer compared with care as usual (CAU). METHODS: The authors conducted a parallel-group randomized controlled trial. Severely fatigued, disease-free survivors of breast cancer who had completed cancer treatment at least 3 months previously were eligible...
June 16, 2017: Cancer
https://www.readbyqxmd.com/read/28616125/mechanisms-of-neurotoxic-symptoms-as-a-result-of-breast-cancer-and-its-treatment-considerations-on-the-contribution-of-stress-inflammation-and-cellular-bioenergetics
#11
REVIEW
Tamara E Lacourt, Cobi J Heijnen
PURPOSE OF REVIEW: Breast cancer and its treatment are associated with a range of neurotoxic symptoms, such as fatigue, cognitive impairment, and pain. Although these symptoms generally subside after treatment completion, they become chronic in a significant subset of patients. We here summarize recent findings on neuroinflammation, stress, and mitochondrial dysfunction as mechanistic pathways leading to neurotoxic symptom experience in breast cancer patients and survivors. RECENT FINDINGS: Neuroinflammation related to stress or cancer treatment and stress resulting from diagnosis, treatment, or (cancer-related) worrying are important predictors of a neurotoxic symptom experience, both during and after treatment for breast cancer...
2017: Current Breast Cancer Reports
https://www.readbyqxmd.com/read/28553684/predictors-of-distress-in-female-breast-cancer-survivors-a-systematic-review
#12
REVIEW
Ania Syrowatka, Aude Motulsky, Siyana Kurteva, James A Hanley, William G Dixon, Ari N Meguerditchian, Robyn Tamblyn
PURPOSE: Unmanaged distress has been shown to adversely affect survival and quality of life in breast cancer survivors. Fortunately, distress can be managed and even prevented with appropriate evidence-based interventions. Therefore, the objective of this systematic review was to synthesize the published literature around predictors of distress in female breast cancer survivors to help guide targeted intervention to prevent distress. METHODS: Relevant studies were located by searching MEDLINE, Embase, PsycINFO, and CINAHL databases...
September 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28551083/the-effects-of-yoga-and-self-esteem-on-menopausal-symptoms-and-quality-of-life-in-breast-cancer-survivors-a-secondary-analysis-of-a-randomized-controlled-trial
#13
Anna K Koch, Sybille Rabsilber, Romy Lauche, Sherko Kümmel, Gustav Dobos, Jost Langhorst, Holger Cramer
OBJECTIVES: Previous research has found that yoga can enhance quality of life and ease menopausal symptoms of breast cancer survivors. The study examined whether self-esteem mediated the effects of yoga on quality of life, fatigue and menopausal symptoms, utilizing validated outcome measures. STUDY DESIGN: This is a secondary analysis of a randomized controlled trial comparing the effects of yoga with those of usual care in 40 breast cancer survivors who suffered from menopausal symptoms...
May 13, 2017: Maturitas
https://www.readbyqxmd.com/read/28500901/the-course-of-cancer-related-fatigue-up-to-ten-years-in-early-breast-cancer-patients-what-impact-in-clinical-practice
#14
Alessandra Fabi, Chiara Falcicchio, Diana Giannarelli, Gabriella Maggi, Francesco Cognetti, Patrizia Pugliese
Little is known about the cancer related fatigue (CRF) along cancer course and risk factors that could predict CRF development and persistence in breast cancer (BC) survivors. This prospective study detected incidence, timing of onset, duration of CRF, impact on QoL and psychological distress. Seventy-eight early BC patients, undergoing chemotherapy (CT) followed or not by hormonal therapy were assessed for QoL and psychological distress by EORTC QLQC30 and HADs questionnaires. Fatigue was investigated with mix methods, structured interview and psychometric measures...
May 10, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28489508/tai-chi-chih-compared-with-cognitive-behavioral-therapy-for-the-treatment-of-insomnia-in-survivors-of-breast-cancer-a-randomized-partially-blinded-noninferiority-trial
#15
RANDOMIZED CONTROLLED TRIAL
Michael R Irwin, Richard Olmstead, Carmen Carrillo, Nina Sadeghi, Perry Nicassio, Patricia A Ganz, Julienne E Bower
Purpose Cognitive behavioral therapy for insomnia (CBT-I) and Tai Chi Chih (TCC), a movement meditation, improve insomnia symptoms. Here, we evaluated whether TCC is noninferior to CBT-I for the treatment of insomnia in survivors of breast cancer. Patients and Methods This was a randomized, partially blinded, noninferiority trial that involved survivors of breast cancer with insomnia who were recruited from the Los Angeles community from April 2008 to July 2012. After a 2-month phase-in period with repeated baseline assessment, participants were randomly assigned to 3 months of CBT-I or TCC and evaluated at months 2, 3 (post-treatment), 6, and 15 (follow-up)...
August 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28470368/breast-cancer-survivors-preferences-for-technology-supported-exercise-interventions
#16
Siobhan M Phillips, David E Conroy, Sarah Kozey Keadle, Christine A Pellegrini, Gillian R Lloyd, Frank J Penedo, Bonnie Spring
PURPOSE: The purpose of this study was to explore breast cancer survivors' interest in and preferences for technology-supported exercise interventions. METHODS: Post-treatment survivors [n = 279; M age = 60.7 (SD = 9.7)] completed a battery of online questionnaires in August 2015. Descriptive statistics were calculated for all data. Logistic regression analyses were conducted to examine relationships between survivors' interest in a technology-supported exercise interventions and demographic, disease, and behavioral factors...
May 3, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28444532/the-utrecht-cohort-for-multiple-breast-cancer-intervention-studies-and-long-term-evaluation-umbrella-objectives-design-and-baseline-results
#17
D A Young-Afat, C H van Gils, H J G D van den Bongard, H M Verkooijen
PURPOSE: In oncology, RCTs are often beset by slow recruitment, limited generalizability, and strong preferences for interventions by patients and physicians. The cohort multiple randomized controlled trial (cmRCT) is an innovative design with the potential to overcome those challenges. In cmRCT, a prospective cohort serves as an infrastructure for multiple RCTs. We implemented cmRCT in a clinical breast cancer setting by creating UMBRELLA-a large prospective cohort of breast cancer and DCIS patients/survivors...
July 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28432781/cognitive-functioning-and-emotion-processing-in-breast-cancer-survivors-and-controls-an-erp-pilot-study
#18
Janine Wirkner, Mathias Weymar, Andreas Löw, Carmen Hamm, Anne-Marie Struck, Clemens Kirschbaum, Alfons O Hamm
Diagnosis and treatment of breast cancer is a very emotionally aversive and stressful life event, which can lead to impaired cognitive functioning and mental health. Breast cancer survivors responding with repressive emotion regulation strategies often show less adaptive coping and adverse outcomes. We investigated cognitive functioning and neural correlates of emotion processing using ERPs. Self-report measures of depression, anxiety, and fatigue, as well as hair cortisol as an index of chronic stress, were assessed...
April 22, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28411330/a-restorative-yoga-intervention-for-african-american-breast-cancer-survivors-a-pilot-study
#19
Teletia R Taylor, Judith Barrow, Kepher Makambi, Vanessa Sheppard, Sherrie Flynt Wallington, Chloe Martin, Danyella Greene, Sri Lakshmi Hyndavi Yeruva, Sara Horton
BACKGROUND: Data show that yoga is effective for improving health-related outcomes in breast cancer survivors. While breast cancer is the most commonly diagnosed cancer among African-American women (AAW), AAW are less likely to engage in yoga compared to other ethnic groups. The goals of the current study were to assess the feasibility of an 8-week restorative yoga program among African-American breast cancer survivors (AA BCS). Specifically, study aims were to (1) measure changes in study outcomes in a restorative yoga (RY) group compared to a wait list control group, (2) assess adherence to the RY program, and (3) assess program satisfaction among study participants...
April 14, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28393991/-quality-of-life-in-chilean-breast-cancer-survivors
#20
M Elisa Irarrázaval, Pascale Kleinman, Fernando Silva R, Loreto Fernández González, Camilo Torres, Marcela Fritis, Carolina Barriga, Herman Waintrub
BACKGROUND: Quality of Life (QOL) assessment may evaluate the impact of diseases and their treatment on the overall well-being of patients. AIM: To assess QOL in Chilean breast cancer survivors. PATIENTS AND METHODS: Ninety one female breast cancer patients aged 60 ± 10 years, who finished their oncologic treatment at least a year prior to the assessment, who were disease free and in medical follow-up were included in the study. They completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 core questionnaire and the breast cancer module QLQ-BR23...
December 2016: Revista Médica de Chile
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