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Hepatocellular carcinoma, li-rads

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https://www.readbyqxmd.com/read/27842889/limitations-of-gd-eob-dtpa-enhanced-mri-can-clinical-parameters-predict-suboptimal-hepatobiliary-phase
#1
M Kobi, V Paroder, M Flusberg, A M Rozenblit, V Chernyak
AIM: To establish cut-off levels of the clinical parameters, which would predict suboptimal 30 minutes delayed hepatobiliary phase (HBP) with high specificity. MATERIALS AND METHODS: This retrospective study included patients with chronic liver disease who underwent hepatocellular carcinoma screening with Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) between 1 January 2011 and 30 November 2014. For each case, HBP was graded as adequate or suboptimal, based on Liver Image Reporting and Data System (LI-RADS) criteria...
November 11, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27801693/change-in-liver-imaging-reporting-and-data-system-characterization-of-focal-liver-lesions-using-gadoxetate-disodium-magnetic-resonance-imaging-compared-with-contrast-enhanced-computed-tomography
#2
Thomas A Hope, Rizwan Aslam, Stefanie Weinstein, Benjamin M Yeh, Carlos U Corvera, Alex Monto, Judy Yee
PURPOSE: The aim of this study was to determine whether gadoxetate-enhanced magnetic resonance imaging (MRI) improves lesion characterization in patients at risk for hepatocellular carcinoma compared with computed tomography (CT). MATERIALS AND METHODS: Forty-nine patients with indeterminate lesions found at contrast-enhanced CT were prospectively enrolled and imaged using gadoxetate-enhanced hepatobiliary phase (HBP) MRI within 30 days of their initial CT. Three readers graded each lesion at CT and MRI using the Liver Imaging Reporting and Data System (LI-RADS) v2014 major criteria and HBP characterization as an ancillary feature...
October 31, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27675631/protocol-rad-0902-a-pilot-study-of-transarterial-chemoembolization-followed-by-stereotactic-radiation-therapy-for-locally-advanced-hepatocellular-carcinoma
#3
L Dover, D DuBay, P Li, D Redden, S Saddekni, S Shen, R Jacob
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27486793/li-rads-ceus-proposal-for-a-contrast-enhanced-ultrasound-algorithm-for-the-diagnosis-of-hepatocellular-carcinoma-in-high-risk-populations
#4
B Schellhaas, D Wildner, L Pfeifer, R S Goertz, A Hagel, M F Neurath, D Strobel
Purpose: To develop a contrast-enhanced ultrasound algorithm (LI-RADS-CEUS = liver imaging reporting and data system with contrast-enhanced ultrasound) for the diagnosis of hepatocellular carcinoma (HCC) in patients at risk. Materials and Methods: A CEUS algorithm (LI-RADS-CEUS) was designed analogously to CT- and MRI-based LI-RADS. LI-RADS-CEUS was evaluated retrospectively in 50 patients at risk with confirmed HCC or non-HCC lesions (test group) with subsequent validation in a prospective cohort of 50 patients (validation group)...
August 3, 2016: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/27474328/liver-imaging-reporting-and-data-system-v2014-categorization-of-hepatocellular-carcinoma-on-gadoxetic-acid-enhanced-mri-comparison-with-multiphasic-multidetector-computed-tomography
#5
Ijin Joo, Jeong Min Lee, Dong Ho Lee, Su Joa Ahn, Eun Sun Lee, Joon Koo Han
PURPOSE: To investigate the Liver Imaging Reporting and Data System (LI-RADS) v2014 categorization of hepatocellular carcinomas (HCCs) on gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-MRI) in comparison with multiphasic multidetector computed tomography (MDCT). MATERIALS AND METHODS: Our Institutional Review Board approved this retrospective study and waived the requirement for informed consent. We included 182 high-risk patients with 216 pathologically confirmed HCCs who underwent both Gd-EOB-MRI at 1...
July 30, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27356833/hepatocellular-carcinoma-with-peliosis-like-change-mimicking-hemangioma-a-li-rads-exception
#6
Giovan Giuseppe Di Costanzo, Giuseppina Marino Marsilia, Raffaella Tortora, Giuseppe Di Costanzo, Alfonso Ragozzino
No abstract text is available yet for this article.
July 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27304548/liver-imaging-reporting-and-data-system-li-rads-version-2014-understanding-and-application-of-the-diagnostic-algorithm
#7
Chansik An, Gulbahor Rakhmonova, Jin-Young Choi, Myeong-Jin Kim
Liver Imaging Reporting and Data System (LI-RADS) is a system for interpreting and reporting of computed tomography and magnetic resonance imaging of the liver in patients at risk for hepatocellular carcinoma (HCC). LI-RADS has been developed to address the limitations of prior imaging-based criteria including the lack of established consensus regarding the exact definitions of imaging features, binary categorization (either definite or not definite HCC), and failure to consider non-HCC malignancies. One of the most important goals of LI-RADS is to facilitate clear communication between all the personnel involved in the diagnosis and treatment of HCC, such as radiologists, hepatologists, surgeons, and pathologists...
June 2016: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/27241148/-diagnostic-value-of-liver-imaging-reporting-and-data-system-mri-on-primary-hepatocellular-carcinoma
#8
Wei Zhao, Wenzheng Li, Xiaoping Yi, Yigang Pei, Hui Liu, Liqing Zhang, Huaping Liu
OBJECTIVE: To evaluate the diagnostic value of liver imaging reporting and classification criteria of data system (LI-RADS) MRI on primary hepatic carcinoma (HCC).
 METHODS: The MRI images of 100 patients (72 patients with HCC, 4 with regenerative nodules, 13 with hemangioma, 4 with liver cyst, 3 with Liver abscess, 2 with inflammatory pseudotumor, 1 with hepatic arteriovenous fistula, 1 with Limitations of steatosis) with liver disease were collected in Xiangya Hospital from January, 2014 to January, 2015...
April 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27193793/rate-of-observation-and-inter-observer-agreement-for-li-rads-major-features-at-ct-and-mri-in-184-pathology-proven-hepatocellular-carcinomas
#9
Eric C Ehman, Spencer C Behr, Sarah E Umetsu, Nicholas Fidelman, Ben M Yeh, Linda D Ferrell, Thomas A Hope
PURPOSE: To compare frequency and inter-reader agreement for LI-RADS v2014 major features at CT vs. MRI in pathology-proven cases of hepatocellular carcinoma. METHODS: Pathology reports and imaging studies from patients having undergone liver transplant or hepatectomy for hepatocellular carcinoma were reviewed. Size, location, washout, and capsule appearance for each lesion were recorded by two radiologists. Cohen's kappa and intraclass correlation coefficients (ICC) were calculated...
May 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27174029/reliability-validity-and-reader-acceptance-of-li-rads-an-in-depth-analysis
#10
Borna K Barth, Olivio F Donati, Michael A Fischer, Erika J Ulbrich, Christoph A Karlo, Anton Becker, Burkhard Seifert, Caecilia S Reiner
RATIONALE AND OBJECTIVES: This study aimed to analyze interreader agreement and diagnostic accuracy of Liver Imaging Reporting and Data System (LI-RADS) in comparison to a nonstandardized 5-point scale and to assess reader acceptance of LI-RADS for clinical routine. MATERIALS AND METHODS: Eighty-four consecutive patients at risk for hepatocellular carcinoma who underwent liver magnetic resonance imaging were included in this Health Insurance Portability and Accountability Act-compliant retrospective study...
September 2016: Academic Radiology
https://www.readbyqxmd.com/read/27115054/imaging-outcomes-of-liver-imaging-reporting-and-data-system-version-2014-category-2-3-and-4-observations-detected-at-ct-and-mr-imaging
#11
Masahiro Tanabe, Akihiko Kanki, Tanya Wolfson, Eduardo A C Costa, Adrija Mamidipalli, Marilia P F D Ferreira, Cynthia Santillan, Michael S Middleton, Anthony C Gamst, Yuko Kono, Alexander Kuo, Claude B Sirlin
Purpose To determine the proportion of untreated Liver Imaging Reporting and Data System (LI-RADS) version 2014 category 2, 3, and 4 observations that progress, remain stable, or decrease in category and to compare the cumulative incidence of progression in category. Materials and Methods In this retrospective, longitudinal, single-center, HIPAA-compliant, institutional review board-approved study, 157 patients (86 men and 71 women; mean age ± standard deviation, 59.0 years ± 9.7) underwent two or more multiphasic computed tomographic (CT) or magnetic resonance (MR) imaging examinations for hepatocellular carcinoma surveillance, with the first examination in 2011 or 2012...
October 2016: Radiology
https://www.readbyqxmd.com/read/27108359/comparison-of-diffusion-weighted-imaging-and-t2-weighted-single-shot-fast-spin-echo-implications-for-li-rads-characterization-of-hepatocellular-carcinoma
#12
Robert M Hicks, Judy Yee, Michael A Ohliger, Stefanie Weinstein, Jeffrey Kao, Nabia S Ikram, Thomas A Hope
PURPOSE: To evaluate the performance of diffusion-weighted imaging (DWI) and T2-weighted single shot fast spin-echo (SSFSE) imaging of the liver in the detection of hepatocellular carcinoma (HCC) in reference to the LI-RADS classification system. METHODS: MR images of 40 patients with 68 LI-RADS grade 3-5 lesions were analyzed. Two readers independently reviewed sequences and characterized lesion signal intensity, followed by consensus evaluation. CE-MRI served as reference standard...
September 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27087012/diagnostic-accuracy-of-liver-imaging-reporting-and-data-system-li-rads-v2014-for-intrahepatic-mass-forming-cholangiocarcinomas-in-patients-with-chronic-liver-disease-on-gadoxetic-acid-enhanced-mri
#13
Ijin Joo, Jeong Min Lee, Sang Min Lee, Jeong Sub Lee, Jin Young Park, Joon Koo Han
PURPOSE: To investigate the utility of Liver Imaging Reporting and Data System (LI-RADS) v2014 for intrahepatic mass-forming cholangiocarcinomas (IMCC) on gadoxetic acid-enhanced magnetic resonance imaging (MRI). MATERIALS AND METHODS: This retrospective study was approved by our Institutional Review Board with waiver of informed consent. Pathologically confirmed IMCCs (n = 35) and hepatocellular carcinomas (HCCs) (n = 71) in patients with chronic hepatitis B or cirrhosis who had undergone gadoxetic acid-enhanced 3...
April 18, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/26885632/liver-imaging-reporting-and-data-system-v2014-with-gadoxetate-disodium-enhanced-magnetic-resonance-imaging-validation-of-li-rads-category-4-and-5-criteria
#14
Sang Hyun Choi, Jae Ho Byun, So Yeon Kim, So Jung Lee, Hyung Jin Won, Yong Moon Shin, Pyo Nyun Kim
OBJECTIVES: The aim of this study was to validate the Liver Imaging Reporting and Data System (LI-RADS) v2014 category 4 (LR-4) and 5 (LR-5) criteria on gadoxetate disodium-enhanced magnetic resonance imaging (MRI) in patients with chronic liver disease. MATERIALS AND METHODS: Between January and December 2012, 300 patients with chronic liver disease who had hepatic nodules 3.0 cm or smaller at surveillance ultrasonography and gadoxetate disodium-enhanced MRI were included...
August 2016: Investigative Radiology
https://www.readbyqxmd.com/read/26866746/imaging-features-of-biphenotypic-primary-liver-carcinoma-hepatocholangiocarcinoma-and-the-potential-to-mimic-hepatocellular-carcinoma-li-rads-analysis-of-ct-and-mri-features-in-61-cases
#15
Theodora A Potretzke, Benjamin R Tan, Maria B Doyle, Elizabeth M Brunt, Jay P Heiken, Kathryn J Fowler
OBJECTIVE: The purpose of this study was to determine the frequency with which biphenotypic primary liver carcinoma (also called hepatocholangiocarcinoma) may be misclassified as hepatocellular carcinoma (HCC) when only Liver Imaging Reporting and Data System (LI-RADS) major features are used and after consideration of ancillary features. MATERIALS AND METHODS: A review of all pathologically proven biphenotypic primary liver carcinomas diagnosed at one institution from 2006 to 2014 was performed...
July 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/26797357/differences-in-liver-imaging-and-reporting-data-system-categorization-between-mri-and-ct
#16
Michael T Corwin, Ghaneh Fananapazir, Michael Jin, Ramit Lamba, Mustafa R Bashir
OBJECTIVE: The purpose of this study is to determine whether focal liver observations are categorized differently by CT and MRI using the Liver Imaging and Reporting Data System (LI-RADS). MATERIALS AND METHODS: We performed a retrospective review of 58 patients at risk for hepatocellular carcinoma who underwent liver protocol CT and MRI within 1 month of each other. Two readers assigned a LI-RADS category for all focal liver observations in consensus. A significant category upgrade was defined as a change from LI-RADS categories 1 and 2 or nonvisualization to LI-RADS categories 3-5, from LI-RADS category 3 to category 4 or 5, from LI-RADS category 4 to category 5, or from any category to LI-RADS category 5V...
February 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/26559157/how-reader-perception-of-capsule-affects-interpretation-of-washout-in-hypervascular-liver-nodules-in-patients-at-risk-for-hepatocellular-carcinoma
#17
Keitaro Sofue, Claude B Sirlin, Brian C Allen, Rendon C Nelson, Carl L Berg, Mustafa R Bashir
PURPOSE: To determine whether reader perception of a capsule affects reader interpretation of washout in hypervascular liver nodules at dynamic magnetic resonance imaging (MRI) in patients at risk for hepatocellular carcinoma (HCC). MATERIALS AND METHODS: This retrospective study was Institutional Review Board (IRB)-approved and Health Insurance Portability and Accountability Act (HIPAA)-compliant, with waiver of informed consent. MRI reports for 111 hypervascular liver nodules (median 2...
June 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/26262514/update-on-the-liver-imaging-reporting-and-data-system-what-the-pathologist-needs-to-know
#18
REVIEW
An Tang, Mark A Valasek, Claude B Sirlin
Hepatocellular carcinoma (HCC) is frequently diagnosed noninvasively with imaging techniques. Computed tomography and magnetic resonance imaging play critical roles in the detection, diagnosis, and staging of HCC. Standardization in the interpretation and reporting of imaging modalities has not existed until recently. In 2008, the American College of Radiology supported the development of the Liver Imaging Reporting and Data System (LI-RADS) for standardized terminology, interpretation, and reporting of imaging examinations for the diagnosis of HCC inpatients at risk for HCC...
September 2015: Advances in Anatomic Pathology
https://www.readbyqxmd.com/read/26119393/classifying-ct-mr-findings-in-patients-with-suspicion-of-hepatocellular-carcinoma-comparison-of-liver-imaging-reporting-and-data-system-and-criteria-free-likert-scale-reporting-models
#19
COMPARATIVE STUDY
Yu-Dong Zhang, Fei-Peng Zhu, Xun Xu, Qing Wang, Chen-Jiang Wu, Xi-Sheng Liu, Hai-Bin Shi
PURPOSE: To compare the Liver Imaging Reporting and Data System (LI-RADS) and a criteria-free Likert scale (LS) reporting models for classifying computed tomography/magnetic resonance imaging (CT/MR) findings of suspicious hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Imaging data of 281 hepatic nodules in 203 patients were retrospectively included. Imaging characteristics including diameter, arterial hyperenhancement, washout, and capsule were reviewed independently by two groups of readers using LI-RADS and LS (range, score 1-5)...
February 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/26104079/added-value-of-a-gadoxetic-acid-enhanced-hepatocyte-phase-image-to-the-li-rads-system-for-diagnosing-hepatocellular-carcinoma
#20
Ningxin Chen, Utaroh Motosugi, Hiroyuki Morisaka, Shintaro Ichikawa, Katsuhiro Sano, Tomoaki Ichikawa, Masanori Matsuda, Hideki Fujii, Hiroshi Onishi
PURPOSE: We investigated the added value of the hypointensity on hepatocyte-phase (HP) imaging of gadoxetic acid-enhanced MRI (EOB-MRI) in the 2014 version of the Liver Imaging Reporting and Data System (LI-RADS) for distinguishing hepatocellular carcinoma (HCC) from benign hepatic lesions in patients with chronic liver disease. METHODS: We retrospectively evaluated targeted lesions (111 HCCs, 28 benign hepatic lesions) of 139 patients (101 men, 38 women; aged 18 to 89 years, mean age, 68 ± 11 years) with chronic liver disease...
2016: Magnetic Resonance in Medical Sciences: MRMS
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