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https://www.readbyqxmd.com/read/28806321/liver-imaging-reporting-and-data-system-discordance-between-computed-tomography-and-gadoxetate-enhanced-magnetic-resonance-imaging-for-detection-of-hepatocellular-carcinoma-major-features
#1
Victoria Chernyak, Milana Flusberg, Amy Law, Mariya Kobi, Viktoriya Paroder, Alla M Rozenblit
PURPOSE: The goal of this study was to compare agreement between computed tomography (CT) and magnetic resonance imaging (MRI) in the evaluation of the major Liver Imaging Reporting and Data System (LI-RADS) features used in assessment of hepatocellular carcinoma: arterial phase hyperenhancement (APHE), portal venous phase washout (WO), capsule appearance (capsule), and largest diameter (diameter). METHODS: Patients with liver protocol CT and gadoxetate-enhanced MRI within 1 month of each other and at least 1 discrete untreated liver lesion were included...
August 12, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28780680/mri-for-hepatocellular-carcinoma-a-primer-for-magnetic-resonance-imaging-interpretation
#2
REVIEW
Tina Sanghvi, James Boyum, Ben Spilseth, Robben Schat, Heather Estby, Andrew Taylor
Hepatocellular carcinoma is among the most prevalent solid organ cancers, and, unlike many cancers, may be diagnosed non-invasively by imaging criteria [1] with the preferred modality recently shifting from multiphasic computed tomography (MDCT) to magnetic resonance imaging (MRI). The purpose of this article is to help facilitate radiologists and radiology trainees in the transition to MRI by providing a step-wise approach to exam interpretation to improve the MRI detection of HCC. A methodical, consistent approach to navigating a HCC screening MRI exam, in conjunction with the LI-RADS framework for characterization, should lead to improved HCC detection and diagnosis...
August 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28780679/locoregional-therapies-for-hepatocellular-carcinoma-and-the-new-li-rads-treatment-response-algorithm
#3
Ania Kielar, Kathryn J Fowler, Sara Lewis, Vahid Yaghmai, Frank H Miller, Hooman Yarmohammadi, Charles Kim, Victoria Chernyak, Takeshi Yokoo, Jeffrey Meyer, Isabel Newton, Richard K Do
Radiologists play a central role in the assessment of patient response to locoregional therapies for hepatocellular carcinoma (HCC). The identification of viable tumor following treatment guides further management and potentially affects transplantation eligibility. Liver Imaging Reporting and Data Systems (LI-RADS) first introduced the concept of LR-treated in 2014, and a new treatment response algorithm is included in the 2017 update to assist radiologists in image interpretation of HCC after locoregional therapy...
August 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28765978/imaging-features-of-hepatocellular-carcinoma-compared-to-intrahepatic-cholangiocarcinoma-and-combined-tumor-on-mri-using-liver-imaging-and-data-system-li-rads-version-2014
#4
Natally Horvat, Ines Nikolovski, Niamh Long, Scott Gerst, Jian Zheng, Linda Ma Pak, Amber Simpson, Junting Zheng, Marinela Capanu, William R Jarnagin, Lorenzo Mannelli, Richard Kinh Gian Do
PURPOSE: To evaluate the prevalence of major and ancillary imaging features from liver imaging reporting and data systems (LI-RADS) version 2014 and their interreader agreement when comparing hepatocellular carcinoma (HCC) to intrahepatic cholangiocarcinoma (ICC) and combined tumor (cHCC-CC). METHODS: The Institutional Review Board approved this HIPAA-compliant retrospective study and waived the requirement for patients' informed consent. Patients with resected HCC (n = 51), ICC (n = 40), and cHCC-CC (n = 11) and available pre-operative contrast-enhanced MRI were included from 2000 to 2015...
August 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28709718/gadoxetic-acid-enhanced-high-temporal-resolution-hepatic-arterial-phase-imaging-with-view-sharing-technique-impact-on-the-li-rads-category
#5
Satoshi Goshima, Yoshifumi Noda, Kimihiro Kajita, Nobuyuki Kawai, Hiromi Koyasu, Hiroshi Kawada, Masayuki Matsuo, Kyongtae T Bae
PURPOSE: To evaluate the value of view-sharing multi-hepatic arterial-phase (mHAP) imaging for diagnosis of hypervascular hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Forty-seven consecutive patients with HCC underwent gadoxetic acid-enhanced magnetic resonance (MR) imaging before angiographic and lipiodol CT. Hepatic arterial-phase images were obtained at 5 consecutive phases with shared central k-space of 25%, followed by portal venous, late (2 and 3min), and hepatobiliary phase imaging...
July 3, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28695233/li-rads-%C3%A2-algorithm-ct-and-mri
#6
REVIEW
Victoria Chernyak, Cynthia S Santillan, Demetri Papadatos, Claude B Sirlin
The Liver Imaging Reporting and Data System (LI-RADS(®)) is an imaging-based diagnostic system applicable in patients at high risk of hepatocellular carcinoma (HCC). In LI-RADS, each liver observation is assigned a category that reflects probability of benignity, HCC, or other malignancy. Familiarity with the LI-RADS diagnostic algorithm is necessary to appropriately implement LI-RADS in clinical practice. This review discusses steps necessary for application of the LI-RADS algorithm and provides examples illustrating each step...
July 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28673446/diagnostic-efficacy-of-the-liver-imaging-reporting-and-data-system-li-rads-with-ct-imaging-in-categorising-small-nodules-10-20%C3%A2-mm-detected-in-the-cirrhotic-liver-at-screening-ultrasound
#7
M Abd Alkhalik Basha, D Abd El Aziz El Sammak, A A El Sammak
AIM: To estimate the diagnostic accuracy of the Liver Imaging-Reporting and Data System (LI-RADS) with computed tomography (CT) for diagnosing hepatic nodules (10-20 mm) detected in cirrhotic livers. MATERIALS AND METHODS: Fifty-five patients with liver cirrhosis and a solitary nodule (10-20 mm in diameter) detected via ultrasound surveillance, underwent hepatic CT and fine-needle biopsy. All the CT images were analysed and the lesions were categorised into five categories according to the LI-RADS...
June 30, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28657851/curative-resection-of-single-primary-hepatic-malignancy-liver-imaging-reporting-and-data-system-category-lr-m-portends-a-worse-prognosis
#8
Chansik An, Sumi Park, Yong Eun Chung, Do-Young Kim, Seung-Seob Kim, Myeong-Jin Kim, Jin-Young Choi
OBJECTIVE: The purpose of this study was to examine the associations between preoperative Liver Imaging Reporting and Data System (LI-RADS) categories and prognosis after curative resection of single hepatic malignancies in patients with chronic liver disease. MATERIALS AND METHODS: Between January 2008 and December 2010, 225 patients with chronic liver disease underwent resection of single hepatic malignant tumors (218 hepatocellular carcinomas, three cholangiocarcinomas, four biphenotypic carcinomas) after undergoing gadoxetic acid-enhanced MRI...
June 28, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28648125/accuracy-of-the-diagnostic-evaluation-of-hepatocellular-carcinoma-with-li-rads
#9
Weimin Liu, Jie Qin, Ruomi Guo, Sidong Xie, Hang Jiang, Xiaohong Wang, Zhuang Kang, Jin Wang, Hong Shan
Background There are few studies about the Liver Imaging Reporting and Data System (LI-RADS), which was developed with the purpose of standardizing the interpretation and reporting of liver imaging examinations in patients at risk for hepatocellular carcinoma (HCC). Purpose To evaluate the diagnostic accuracy of HCC diagnosis using LI-RADS. Material and Methods The computed tomography (CT), magnetic resonance imaging (MRI), and clinical data of 297 lesions in 249 patients between June 2012 and August 2013 were retrospectively analyzed...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28647768/li-rads-%C3%A2-ancillary-features-on-ct-and-mri
#10
REVIEW
Victoria Chernyak, An Tang, Milana Flusberg, Demetri Papadatos, Bijan Bijan, Yuko Kono, Cynthia Santillan
The Liver Imaging Reporting and Data System (LI-RADS) uses an algorithm to assign categories that reflect the probability of hepatocellular carcinoma (HCC), non-HCC malignancy, or benignity. Unlike other imaging algorithms, LI-RADS utilizes ancillary features (AFs) to refine the final category. AFs in LI-RADS v2017 are divided into those favoring malignancy in general, those favoring HCC specifically, and those favoring benignity. Additionally, LI-RADS v2017 provides new rules regarding application of AFs. The purpose of this review is to discuss ancillary features included in LI-RADS v2017, the rationale for their use, potential pitfalls encountered in their interpretation, and tips on their application...
June 24, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28647765/epidemiology-of-hepatocellular-carcinoma-target-population-for-surveillance-and-diagnosis
#11
REVIEW
An Tang, Oussama Hallouch, Victoria Chernyak, Aya Kamaya, Claude B Sirlin
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer mortality worldwide. Incidence rates of liver cancer vary widely between geographic regions and are highest in Eastern Asia and sub-Saharan Africa. In the United States, the incidence of HCC has increased since the 1980s. HCC detection at an early stage through surveillance and curative therapy has considerably improved the 5-year survival. Therefore, medical societies advocate systematic screening and surveillance of target populations at particularly high risk for developing HCC to facilitate early-stage detection...
June 24, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28634619/implementation-of-li-rads-into-a-radiological-practice
#12
REVIEW
Stefan T Siedlikowski, Ania Z Kielar, Eleanor L Ormsby, Bijan Bijan, Christopher Kagay
Since its introduction in 2011, Liver Imaging Reporting and Data System (LI-RADS) has become an increasingly utilized method for radiologists to categorize lesions for hepatocellular carcinoma (HCC) in patients at risk (American College of Radiology, www.acr.org/quality-safety/resources/lirads 2016). This overview article presents insight into methods of incorporating LI-RADS into an existing clinical practice, highlighting concrete ways to establish this system as a mainstay in any radiologist's evidence-based armamentarium...
June 20, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28612162/li-rads-and-transplantation-for-hepatocellular-carcinoma
#13
REVIEW
An Tang, Kathryn J Fowler, Victoria Chernyak, William C Chapman, Claude B Sirlin
Patients with hepatocellular carcinoma (HCC) may be eligible for liver transplantation. Liver transplant candidates with HCC compete for the same deceased donor organs as those without HCC. These scarce organs must be allocated fairly and justly to those who will benefit most. Unlike most other cancers, HCC is often diagnosed noninvasively by imaging without biopsy confirmation. Therefore, radiologists play an important role in diagnosing definite HCC (i.e., LR-5 category) that counts toward staging and determination of liver transplant eligibility...
June 13, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28609205/diagnostic-performance-of-gadoxetic-acid-enhanced-liver-mr-imaging-versus-multidetector-ct-in-the-detection-of-dysplastic-nodules-and-early-hepatocellular-carcinoma
#14
Bo Ram Kim, Jeong Min Lee, Dong Ho Lee, Jeong Hee Yoon, Bo Yun Hur, Kyung Suk Suh, Nam-Joon Yi, Kyung Boon Lee, Joon Koo Han
Purpose To compare the diagnostic performance of gadoxetic acid-enhanced liver magnetic resonance (MR) imaging with that of contrast material-enhanced multidetector computed tomography (CT) in the detection of borderline hepatocellular nodules in patients with liver cirrhosis and to determine the Liver Imaging Reporting and Data System (LI-RADS) categories of these detected nodules. Materials and Methods The institutional review board approved this retrospective study and waived the informed consent requirement...
June 13, 2017: Radiology
https://www.readbyqxmd.com/read/28580538/li-rads-m-lr-m-definite-or-probable-malignancy-not-specific-for-hepatocellular-carcinoma
#15
Kathryn J Fowler, Theodora A Potretzke, Thomas A Hope, Eduardo A Costa, Stephanie R Wilson
LI-RADS v2017 introduces major changes to the diagnostic criteria for LR-M observations to better guide radiologists in the use of this malignant category designation. LR-M is intended to preserve the specificity of the LI-RADS algorithm for diagnosis of HCC while not losing sensitivity for diagnosis of malignancy. The purpose of this paper is to provide a brief background on LR-M, discuss the diagnostic criteria new to v2017, special considerations for its application, and management implications.
June 3, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28562394/diagnostic-accuracy-of-contrast-enhanced-ultrasound-for-the-differential-diagnosis-of-hepatocellular-carcinoma-esculap-versus-ceus-li-rads
#16
Barbara Schellhaas, Ruediger S Görtz, Lukas Pfeifer, Christian Kielisch, Markus F Neurath, Deike Strobel
OBJECTIVE: A comparison is made of two contrast-enhanced ultrasound (CEUS) algorithms for the diagnosis of hepatocellular carcinoma (HCC) in high-risk patients: Erlanger Synopsis of Contrast-enhanced Ultrasound for Liver lesion Assessment in Patients at Risk (ESCULAP) and American College of Radiology Contrast-Enhanced Ultrasound-Liver Imaging Reporting and Data System (ACR-CEUS-LI-RADSv.2016). PATIENTS AND METHODS: Focal liver lesions in 100 high-risk patients were assessed using both CEUS algorithms (ESCULAP and CEUS-LI-RADSv...
September 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28558068/diagnostic-accuracy-of-gadoxetic-acid-enhanced-mr-for-small-hypervascular-hepatocellular-carcinoma-and-the-concordance-rate-of-liver-imaging-reporting-and-data-system-li-rads
#17
Jae Seok Bae, Jung Hoon Kim, Mi Hye Yu, Dong Ho Lee, Hyo-Cheol Kim, Jin Wook Chung, Joon Koo Han
BACKGROUND & AIMS: To assess diagnostic accuracy of gadoxetic acid-enhanced MR for small hypervascular hepatocellular carcinoma (HCC) detected by C-arm CT and concordance rate of Liver Imaging Reporting and Data System (LI-RADS). METHODS: In this retrospective study, we recruited 4,544 patients suspected of having HCC underwent C-arm CT from November 2008 to May 2013. Among these patients, gadoxetic acid-enhanced MR was performed in 167 patients with HCC (n = 379; 257 > 1 cm, 122 ≤ 1 cm)...
2017: PloS One
https://www.readbyqxmd.com/read/28556283/computer-aided-diagnosis-program-for-classifying-the-risk-of-hepatocellular-carcinoma-on-mr-images-following-liver-imaging-reporting-and-data-system-li-rads
#18
Youngwoo Kim, Alessandro Furlan, Amir A Borhani, Kyongtae T Bae
PURPOSE: To develop and evaluate a computer-aided diagnosis (CAD) program for liver lesions on magnetic resonance (MR) images for classification of the risk of hepatocellular carcinoma (HCC) following the liver imaging reporting and data system (LI-RADS). MATERIALS AND METHODS: Liver MR images from 41 patients with hyperenhancing liver lesions categorized as LR 3, 4, and 5 were evaluated by two radiologists. The major LI-RADS features of each index liver lesion were recorded, including size (maximum transverse diameter), presence of hyperenhancement, washout appearance, and capsule appearance...
May 26, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28553196/diagnostic-imaging-of-hepatocellular-carcinoma-a-pictorial-essay
#19
Tomasz K Nowicki, Karolina Markiet, Edyta Szurowska
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, which develops mostly in the setting of chronic liver disease. European Association for the Study of the Liver (EASL) and European Organization for Research and Treatment of Cancer (EORTC) prepared guidelines for screening, follow-up and diagnosis of HCC to facilitate decision making and optimize both diagnostic and therapeutic protocols. The review briefly describes etiology, epidemiology and histopathology of HCC and presents EASL-EORTC guidelines for surveillance and diagnosis of HCC...
May 2017: Current Medical Imaging Reviews
https://www.readbyqxmd.com/read/28483546/impact-of-a-structured-report-template-on-the-quality-of-ct-and-mri-reports-for-hepatocellular-carcinoma-diagnosis
#20
Milana Flusberg, Jeremy Ganeles, Tulay Ekinci, Shlomit Goldberg-Stein, Viktoriya Paroder, Mariya Kobi, Victoria Chernyak
PURPOSE: To assess the impact of a Liver Imaging Reporting and Data System (LI-RADS) structured template on quality of reports for hepatocellular carcinoma (HCC). MATERIALS AND METHODS: A departmental structured LI-RADS template was adopted in April 2015. CT and MRI reports from September 2014 to February 2016 with probable or definite HCC were reviewed. Reporting of the following was recorded for each lesion and compared between template and free-text reports: (1) LI-RADS category, (2) Couinaud segment, and (3) unequivocal description of presence or absence of major LI-RADS HCC features: arterial phase hyperenhancement, "washout," diameter, threshold growth, and "capsule...
May 5, 2017: Journal of the American College of Radiology: JACR
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