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https://www.readbyqxmd.com/read/28428655/magnetic-resonance-imaging-of-the-cirrhotic-liver-diagnosis-of-hepatocellular-carcinoma-and-evaluation-of-response-to-treatment-part-2
#1
REVIEW
Miguel Ramalho, António P Matos, Mamdoh AlObaidy, Fernanda Velloni, Ersan Altun, Richard C Semelka
In the second part of this review, we will describe the ancillary imaging features of hepatocellular carcinoma (HCC) that can be seen on standard magnetic resonance imaging (MRI) protocol, and on novel and emerging protocols such as diffusion weighted imaging and utilization of hepatocyte-specific/hepatobiliary contrast agent. We will also describe the morphologic sub-types of HCC, and give a simplified non-invasive diagnostic algorithm for HCC, followed by a brief description of the liver imaging reporting and data system (LI-RADS), and MRI assessment of tumor response following locoregional therapy...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28395852/diagnosis-of-hepatocellular-carcinoma-an-update-on-international-guidelines
#2
C Cassinotto, C Aubé, A Dohan
Imaging is essential for the successful management of patients with or at risk of developing hepatocellular carcinoma (HCC). If ultrasound remains the key screening modality, computed tomography and magnetic resonance imaging (MRI) can play a major role in the characterization and noninvasive diagnosis of nodules in patients at risk of developing HCC. Each technique has succeeded in adapting to the wide histological spectrum of focal liver lesions. In this review, we discuss recent advancements in imaging techniques and evaluation - notably diffusion-weighted imaging, contrast-enhanced ultrasound, and liver-specific MRI contrast agents - as well as their addition to international guidelines and reporting systems such as the Liver imaging reporting and data system (LI-RADS)...
April 5, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28374073/liver-imaging-reporting-and-data-system-on-ct-and-gadoxetic-acid-enhanced-mri-with-diffusion-weighted-imaging
#3
Dong Ik Cha, Kyung Mi Jang, Seong Hyun Kim, Tae Wook Kang, Kyoung Doo Song
OBJECTIVES: To assess major imaging features of Liver Imaging Reporting and Data System (LI-RADS) on contrast-enhanced CT and gadoxetic acid-enhanced MRI and to estimate whether the combination of signal intensity favouring HCC on hepatobiliary phase (HBP) and diffusion-weighted images (DWI) can act as a major feature in LI-RADS. METHODS: Four hundred twenty one patients with 445 observations were included. Major features of LI-RADS on CT and MRI as well as HBP and DWI features were assessed...
April 3, 2017: European Radiology
https://www.readbyqxmd.com/read/28352950/effect-of-threshold-growth-as-a-major-feature-on-li-rads-categorization
#4
Victoria Chernyak, Mariya Kobi, Milana Flusberg, Kate C Fruitman, Claude B Sirlin
PURPOSE: Liver Imaging Reporting and Data System (LI-RADS) uses major features (arterial phase hyperenhancement [APHE], "washout" [WO], "capsule," diameter, threshold growth [TG]) to codify probability of hepatocellular carcinoma for each observation. This study assessed the effect of removing TG as a major feature on LI-RADS categorization. MATERIALS AND METHODS: In this HIPAA-compliant, IRB-approved study, all MR and CT clinical reports containing a standardized LI-RADS v2014 template between 4/15-1/17 were retrospectively reviewed for each LR-3, LR-4, and LR-5 reported observation...
March 28, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28329875/american-college-of-radiology-contrast-enhanced-ultrasound-liver-imaging-reporting-and-data-system-ceus-li-rads-for-the-diagnosis-of-hepatocellular-carcinoma-a-pictorial-essay
#5
Fabio Piscaglia, Stephanie R Wilson, Andrej Lyshchik, David Cosgrove, Christoph F Dietrich, Hyun-Jung Jang, Tae Kyoung Kim, Veronica Salvatore, Juergen Karl Willmann, Claude B Sirlin, Yuko Kono
No abstract text is available yet for this article.
March 22, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/28297726/-li-rads-ceus-for-the-classification-of-hcc-risk-in-liver-lesions
#6
T Karlas
No abstract text is available yet for this article.
March 15, 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/28255543/liver-imaging-reporting-and-data-system-an-expert-consensus-statement
#7
EDITORIAL
Khaled M Elsayes, Ania Z Kielar, Michelle M Agrons, Janio Szklaruk, An Tang, Mustafa R Bashir, Donald G Mitchell, Richard K Do, Kathryn J Fowler, Victoria Chernyak, Claude B Sirlin
The increasing incidence and high morbidity and mortality of hepatocellular carcinoma (HCC) have inspired the creation of the Liver Imaging Reporting and Data System (LI-RADS). LI-RADS aims to reduce variability in exam interpretation, improve communication, facilitate clinical therapeutic decisions, reduce omission of pertinent information, and facilitate the monitoring of outcomes. LI-RADS is a dynamic process, which is updated frequently. In this article, we describe the LI-RADS 2014 version (v2014), which marks the second update since the initial version in 2011...
2017: Journal of Hepatocellular Carcinoma
https://www.readbyqxmd.com/read/28249329/letter-to-the-editor-on-li-rads-ceus-proposal-for-a-contrast-enhanced-ultrasound-algorithm-for-the-diagnosis-of-hepatocellular-carcinoma-in-high-risk-populations-ultraschall-in-med-2016-37-627-634
#8
https://www.readbyqxmd.com/read/28249328/contrast-enhanced-ultrasound-ceus-liver-imaging-reporting-and-data-system-li-rads%C3%A2-the-official-version-by-the-american-college-of-radiology-acr
#9
Yuko Kono, Andrej Lyshchik, David Cosgrove, Christoph F Dietrich, Hyun-Jung Jang, Tae Kyoung Kim, Fabio Piscaglia, Juergen K Willmann, Stephanie R Wilson, Cynthia Santillan, Avinash Kambadakone, Donald Mitchell, Alexander Vezeridis, Claude B Sirlin
No abstract text is available yet for this article.
January 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/28154018/hepatic-lesions-in-a-cirrhotic-liver-primary-or-metastases
#10
Lorenzo Mannelli, Serena Monti, Verena Grieco, Manuela Matesan
Although prior studies showed that patients with cirrhosis have a lower risk of developing liver metastases, appropriate workup of incidental liver masses in cirrhotic liver is important for a correct diagnosis. Here we present a case of newly diagnosed liver cirrhosis with multifocal hepatic lesions, which was initially categorized as a LI-RADS (Liver Imaging Reporting and Data System) 5 lesions. Scintigraphy with (111)In-pentetreotide (Octreoscan) indicated a suspected thyroid nodule, later confirmed to represent medullary thyroid carcinoma lesion...
March 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28104315/implementing-a-structured-reporting-initiative-using-a-collaborative-multistep-approach
#11
Shlomit Goldberg-Stein, William R Walter, E Stephen Amis, Meir H Scheinfeld
PURPOSE: To describe the successful implementation of a structured reporting initiative in a large urban academic radiology department. METHODS: We describe our process, compromises, and top 10 lessons learned in overhauling traditional reporting practices and comprehensively implementing structured reporting at our institution. To achieve our goals, we took deliberate steps toward consensus building, undertook multistep template refinement, and achieved close collaboration with the technical staff, department coders, and hospital information technologists...
December 15, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28027763/increased-interreader-agreement-in-diagnosis-of-hepatocellular-carcinoma-using-an-adapted-li-rads-algorithm
#12
Anton S Becker, Borna K Barth, Paulo H Marquez, Olivio F Donati, Erika J Ulbrich, Christoph Karlo, Cäcilia S Reiner, Michael A Fischer
PURPOSE: To evaluate a simplified Liver Imaging Reporting and Data System (LI-RADS) algorithm to improve interreader agreement while maintaining diagnostic performance for HCC. MATERIALS AND METHODS: MRI scans of 84 cirrhotic patients with 104 distinct liver observations were retrospectively selected to equivocally match each of the LI-RADS grades (LR1-5) using histopathology and imaging follow up as standard of reference. Four independent radiologists categorized all observations as benign (LR1-2) or potentially malignant (LR3-5) and determined LI-RADS based imaging features including observation size, arterial phase hyperenhancement, washout, capsule appearance and threshold growth for LR3-5 observations and timed their readouts...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/27842889/limitations-of-gd-eob-dtpa-enhanced-mri-can-clinical-parameters-predict-suboptimal-hepatobiliary-phase
#13
M Kobi, V Paroder, M Flusberg, A M Rozenblit, V Chernyak
AIM: To establish cut-off levels of the clinical parameters, which would predict suboptimal 30 minutes delayed hepatobiliary phase (HBP) with high specificity. MATERIALS AND METHODS: This retrospective study included patients with chronic liver disease who underwent hepatocellular carcinoma screening with Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) between 1 January 2011 and 30 November 2014. For each case, HBP was graded as adequate or suboptimal, based on Liver Image Reporting and Data System (LI-RADS) criteria...
January 2017: Clinical Radiology
https://www.readbyqxmd.com/read/27801693/change-in-liver-imaging-reporting-and-data-system-characterization-of-focal-liver-lesions-using-gadoxetate-disodium-magnetic-resonance-imaging-compared-with-contrast-enhanced-computed-tomography
#14
Thomas A Hope, Rizwan Aslam, Stefanie Weinstein, Benjamin M Yeh, Carlos U Corvera, Alex Monto, Judy Yee
PURPOSE: The aim of this study was to determine whether gadoxetate-enhanced magnetic resonance imaging (MRI) improves lesion characterization in patients at risk for hepatocellular carcinoma compared with computed tomography (CT). MATERIALS AND METHODS: Forty-nine patients with indeterminate lesions found at contrast-enhanced CT were prospectively enrolled and imaged using gadoxetate-enhanced hepatobiliary phase (HBP) MRI within 30 days of their initial CT. Three readers graded each lesion at CT and MRI using the Liver Imaging Reporting and Data System (LI-RADS) v2014 major criteria and HBP characterization as an ancillary feature...
October 31, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27486793/li-rads-ceus-proposal-for-a-contrast-enhanced-ultrasound-algorithm-for-the-diagnosis-of-hepatocellular-carcinoma-in-high-risk-populations
#15
B Schellhaas, D Wildner, L Pfeifer, R S Goertz, A Hagel, M F Neurath, D Strobel
Purpose: To develop a contrast-enhanced ultrasound algorithm (LI-RADS-CEUS = liver imaging reporting and data system with contrast-enhanced ultrasound) for the diagnosis of hepatocellular carcinoma (HCC) in patients at risk. Materials and Methods: A CEUS algorithm (LI-RADS-CEUS) was designed analogously to CT- and MRI-based LI-RADS. LI-RADS-CEUS was evaluated retrospectively in 50 patients at risk with confirmed HCC or non-HCC lesions (test group) with subsequent validation in a prospective cohort of 50 patients (validation group)...
December 2016: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/27474328/liver-imaging-reporting-and-data-system-v2014-categorization-of-hepatocellular-carcinoma-on-gadoxetic-acid-enhanced-mri-comparison-with-multiphasic-multidetector-computed-tomography
#16
Ijin Joo, Jeong Min Lee, Dong Ho Lee, Su Joa Ahn, Eun Sun Lee, Joon Koo Han
PURPOSE: To investigate the Liver Imaging Reporting and Data System (LI-RADS) v2014 categorization of hepatocellular carcinomas (HCCs) on gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-MRI) in comparison with multiphasic multidetector computed tomography (MDCT). MATERIALS AND METHODS: Our Institutional Review Board approved this retrospective study and waived the requirement for informed consent. We included 182 high-risk patients with 216 pathologically confirmed HCCs who underwent both Gd-EOB-MRI at 1...
July 30, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27356833/hepatocellular-carcinoma-with-peliosis-like-change-mimicking-hemangioma-a-li-rads-exception
#17
Giovan Giuseppe Di Costanzo, Giuseppina Marino Marsilia, Raffaella Tortora, Giuseppe Di Costanzo, Alfonso Ragozzino
No abstract text is available yet for this article.
July 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27304548/liver-imaging-reporting-and-data-system-li-rads-version-2014-understanding-and-application-of-the-diagnostic-algorithm
#18
Chansik An, Gulbahor Rakhmonova, Jin-Young Choi, Myeong-Jin Kim
Liver Imaging Reporting and Data System (LI-RADS) is a system for interpreting and reporting of computed tomography and magnetic resonance imaging of the liver in patients at risk for hepatocellular carcinoma (HCC). LI-RADS has been developed to address the limitations of prior imaging-based criteria including the lack of established consensus regarding the exact definitions of imaging features, binary categorization (either definite or not definite HCC), and failure to consider non-HCC malignancies. One of the most important goals of LI-RADS is to facilitate clear communication between all the personnel involved in the diagnosis and treatment of HCC, such as radiologists, hepatologists, surgeons, and pathologists...
June 2016: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/27241148/-diagnostic-value-of-liver-imaging-reporting-and-data-system-mri-on-primary-hepatocellular-carcinoma
#19
Wei Zhao, Wenzheng Li, Xiaoping Yi, Yigang Pei, Hui Liu, Liqing Zhang, Huaping Liu
OBJECTIVE: To evaluate the diagnostic value of liver imaging reporting and classification criteria of data system (LI-RADS) MRI on primary hepatic carcinoma (HCC).
 METHODS: The MRI images of 100 patients (72 patients with HCC, 4 with regenerative nodules, 13 with hemangioma, 4 with liver cyst, 3 with Liver abscess, 2 with inflammatory pseudotumor, 1 with hepatic arteriovenous fistula, 1 with Limitations of steatosis) with liver disease were collected in Xiangya Hospital from January, 2014 to January, 2015...
April 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27193793/rate-of-observation-and-inter-observer-agreement-for-li-rads-major-features-at-ct-and-mri-in-184-pathology-proven-hepatocellular-carcinomas
#20
Eric C Ehman, Spencer C Behr, Sarah E Umetsu, Nicholas Fidelman, Ben M Yeh, Linda D Ferrell, Thomas A Hope
PURPOSE: To compare frequency and inter-reader agreement for LI-RADS v2014 major features at CT vs. MRI in pathology-proven cases of hepatocellular carcinoma. METHODS: Pathology reports and imaging studies from patients having undergone liver transplant or hepatectomy for hepatocellular carcinoma were reviewed. Size, location, washout, and capsule appearance for each lesion were recorded by two radiologists. Cohen's kappa and intraclass correlation coefficients (ICC) were calculated...
May 2016: Abdominal Radiology
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