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Alveolar cleft

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https://www.readbyqxmd.com/read/28806380/formation-of-the-philtral-column-using-a-dermal-graft-in-secondary-unilateral-cleft-lip
#1
Jeenam Kim, Jongok Park, Ki-Il Uhm, Donghyeok Shin, Hyungon Choi
INTRODUCTION: The philtral column has an important aesthetic significance and is especially important in patients with cleft lip. If the integrity of the philtrum cannot be preserved in patients of unilateral clefts, these patients will have profound abnormalities in their facial musculature. The purpose of this study was to analyze the effects of dermal grafting on the philtral column in patients with a unilateral alveolar cleft. METHODS: The authors retrospectively studied dermal grafts performed in Konkuk University Medical Center between January 2009 and January 2015...
August 10, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28796987/evaluation-of-periodontal-tissues-in-growing-patients-with-bilateral-cleft-lip-and-palate-a-pilot-study
#2
Beata Wyrębek, Dorota Cudziło, Paweł Plakwicz
AIM: To evaluate the periodontal status, mucogingival parameters and oral hygiene in growing patients with bilateral cleft lip and palate. MATERIAL AND METHODS: Assessment was performed in 15 patients aged 6 to 18 years with a bilateral cleft. Records included probing pocket depth, clinical attachment level, keratinized gingiva, recession, vestibule depth, biotype, type of fraena, dental plaque and bleeding. RESULTS: The mean scores of pocket depth were: 1...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28774851/a-prospective-study-of-chin-bone-graft-harvesting-for-unilateral-maxillary-alveolar-cleft-during-mixed-dentition
#3
AliReza Shirzadeh, Amin Rahpeyma, Saeedeh Khajehahmadi
PURPOSE: The chin is a common donor site for alveolar cleft bone grafting. The amount of bone available at this site can be limited, because conservative harvesting with mixed dentition must consider the incisive nerve, the unerupted mandibular canine, and the integrity of the inferior mandibular border. MATERIALS AND METHODS: Patients with nonsyndromic unilateral alveolar cleft in the mixed dentition stage were selected for this study. The volume of bone obtained from the mandibular symphysis (symphysis menti), degree of alteration in lower lip sensation, anterior tooth vitality, remaining bone in the alveolar cleft, and bone defects at the donor site 1 year after surgery were evaluated...
July 10, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28765038/synergistic-effect-of-1%C3%AE-25-dihydroxyvitamin-d3-and-17%C3%AE-estradiol-on-osteoblast-differentiation-of-pediatric-mscs
#4
Jing Li, Bonnie L Padwa, Shuanhu Zhou, Julia Mullokandova, Meryl S LeBoff, Julie Glowacki
Vitamin D is essential for mineral homeostasis and contributes to bone metabolism by stimulating osteoblast differentiation of marrow stromal cells (MSCs). In this study, we used MSCs from pre-pubertal girls and boys to test the hypothesis that 1α,25(OH)2D and 17β-estradiol have synergistic effects on these MSCs, and what mechanism is involved. With IRB approval, we isolated MSCs from discarded excess iliac marrow graft from children undergoing alveolar cleft repair. Plasma was available from 8 female (9...
July 29, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28747097/tissue-engineering-strategies-to-improve-osteogenesis-in-the-juvenile-swine-alveolar-cleft-model
#5
Montserrat Caballero, Donna C Jones, Zhengyuan Shan, Sajjad Soleimani, John A van Aalst
Alveolar <b>(gumline)</b> clefts are the most common congenital bone defect in humans, affecting 1 in 700 live births. Treatment <b>to repair these bony</b> defects relies on autologous, <b>cancellous</b> bone transfer from the iliac crest. This harvest requires a second surgical site <b>with increased </b>surgical time associated with potential complications, <b>while providing only limited cancellous bone</b>. Improvements in treatment protocols that avoid these limitations would be beneficial to patients with clefts and other craniofacial bone defects...
July 26, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28746298/reply-alveolar-bone-grafting-and-cleft-lip-and-palate-a-review
#6
LETTER
Elizabeth Hope Weissler, Peter J Taub
No abstract text is available yet for this article.
August 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28746297/alveolar-bone-grafting-and-cleft-lip-and-palate-a-review
#7
LETTER
Xiao-Lin Liu, Bing Shi, Qian Zheng, Cheng-Hao Li
No abstract text is available yet for this article.
August 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28746285/a-comparative-analysis-of-recombinant-human-bone-morphogenetic-protein-2-with-a-demineralized-bone-matrix-versus-iliac-crest-bone-graft-for-secondary-alveolar-bone-grafts-in-patients-with-cleft-lip-and-palate-review-of-501-cases
#8
Jeffrey A Hammoudeh, Artur Fahradyan, Daniel J Gould, Fan Liang, Thomas Imahiyerobo, Leo Urbinelli, JoAnna T Nguyen, William Magee, Stephen Yen, Mark M Urata
BACKGROUND: Alveolar cleft reconstruction using iliac crest bone graft is considered standard of care for children with complete cleft lip and palate at the time of mixed dentition. Harvesting bone may result in donor-site morbidity and additional operating time and length of hospitalization. Recombinant human bone morphogenetic protein (rhBMP)-2 with a demineralized bone matrix is an alternative bone source for alveolar cleft reconstruction. The authors investigated the outcomes of rhBMP-2/demineralized bone matrix versus iliac crest bone graft for alveolar cleft reconstruction by reviewing postoperative surgical complications and cleft closure...
August 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28740330/soft-tissue-molding-technique-in-cleft-lip-and-palate-patient-using-laser-surgery-in-combination-with-orthodontic-appliance-a-case-report
#9
Pornpat Theerasopon, Tasanee Wangsrimongkol, Sajee Sattayut
BACKGROUND: Although surgical treatment protocols for cleft lip and palate patients have been established, many patients still have some soft tissue defects after complete healing from surgical interventions. These are excess soft tissue, high attached fraena and firmed tethering scares. These soft tissue defects resulted shallowing of vestibule, restricted tooth movement, compromised periodontal health and trended to limit the maxillary growth. The aim of this case report was to present a method of correcting soft tissue defects after conventional surgery in cleft lip and palate patient by using combined laser surgery and orthodontic appliance...
March 31, 2017: Laser Therapy
https://www.readbyqxmd.com/read/28737562/dynamic-cleft-maxillary-orthopedics-and-periosteoplasty-25-patients-25-years
#10
Frederick N Lukash, Lauren B Shikowitz-Behr, Michael Schwartz, Frank Tuminelli
In 1985 this cleft team, dissatisfied with the treatment and results from cleft lip and palate repair, began a longitudinal long-term study using dynamic maxillary orthopedics and periosteoplasty as was originally described by Drs Millard and Latham. All cases were carefully documented through adolescence, including clinical assessments, orthodontic, radiographic, and cephalometric analyses. In 1998, in this journal, we published our data on 35 complete unilateral and 10 complete bilateral cleft patients. At that time facial growth was following normal cephalometric patterns...
July 22, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28732218/invasiveness-of-tibial-bone-graft-harvesting-for-secondary-alveolar-bone-grafting-can-harvesting-be-made-at-the-age-of-less-than-10%C3%A2-years-without-complications
#11
Kohta Fukuta, Kenichi Kurita, Atsushi Nakayama, Masahito Maeda, Hiroshi Watanabe, Mitsuo Goto
PURPOSE: In this study, particulate cancellous bone marrow was harvested from the tibia for alveolar bone grafting, and postoperative complications at the donor site were compared between patients aged 10 years or older (29 tibias) and those aged younger than 10 years (42 tibias). PATIENTS AND METHODS: Enrolled patients were those who underwent tibial bone graft harvesting at the Department of Oral and Maxillofacial Surgery, Aichi Gakuin University, during a period of 3 years and 1 month from March 2012 through March 2015...
June 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28708645/a-digital-assessment-of-the-maxillary-deformity-correction-in-infants-with-bilateral-cleft-lip-and-palate-using-computer-aided-nasoalveolar-molding
#12
Xin Gong, Jun Zhao, Jiawei Zheng, Quan Yu
OBJECTIVES: To evaluate the maxillary alveolar repositioning of the infants with bilateral cleft lip and palate (BCLP) undergoing computer-aided nasoalveolar molding (CAD-NAM). METHODS: A total of 19 BCLP infants undergoing CAD-NAM were recruited as the treatment group, and 21 nonpresurgically treated BCLP patients served as controls. The upper alveolar morphology was measured and evaluated. Changes in all variables between pre- and post-CAD-NAM were compared. RESULTS: By the end of CAD-NAM, significant difference was found in the P-A, P'-A', and L-ideal midline (P < 0...
July 13, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28708639/pulp-vitality-of-maxillary-canines-after-alveolar-cleft-bone-grafting-pulse-oximetry-versus-electric-pulp-test-versus-cold-test
#13
Abbas Ali Khademi, Maryam Montazeri Shahtouri, Bijan Movahedian Attar, Niloofar Rikhtegaran
OBJECTIVES: Assessment of pulp vitality is necessary prior to any dental treatment. The purpose of this study was to assess pulp vitality of bilateral canines in unilateral cleft patients following alveolar bone graft surgery using pulse oximetry, electrical pulp test, and cold test. METHODS: This analytical, cross-sectional study was conducted on canines of 20 unilateral cleft patients who had alveolar bone graft surgery. Pulp vitality of canines was evaluated postoperatively by pulse oximetry, electrical pulp test, and cold test...
July 13, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28708467/gender-differences-in-surgical-treatment-of-patients-with-cleft-lip-and-palate
#14
Anna Paganini, Camilla Hörfelt, Hans Mark
Numerous gender-based differences in medical treatment have been recognized due to conscious or unconscious perceptions, i.e. gender bias. The aim of the present study was to investigate whether gender differences exist in the surgical treatment of patients with cleft lip and palate (CLP) anomalies. This study is a retrospective review of 235 consecutive patients with non-syndromic unilateral CLP or bilateral CLP born between 1966 and 1986. Each chart was reviewed, and 2178 surgical procedures were registered and categorized as primary surgery (primary lip, palatal and alveolar repair) or secondary surgery (aesthetic and functional revision)...
July 14, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28699387/low-laser-therapy-a-strategy-to-promote-the-osteogenic-differentiation-of-deciduous-dental-pulp-stem-cells-from-cleft-lip-and-palate-patients
#15
Carla Cristina Gomes Pinheiro, Milena Correa de Pinho, Ana Cecília Corrêa Aranha, Eduardo Fregnani, Daniela Franco Bueno
Dental pulp stem cells (DPSC) can undergo several types of differentiation, including osteogenic differentiation. One osteogenesis-inducing factor that has been previously described is "in vitro" low-level laser irradiation of cells. Laser irradiation promotes the acceleration of bone matrix mineralization of the cell strain. However, no consensus exists regarding the dose and treatment time. We used DPSC strains from cleft lip and palate patients because new bone tissue engineering strategies have used DPSC in preclinical and clinical trials for the rehabilitation of alveolar bone clefts...
July 12, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28684068/analyzing-the-teeth-next-to-the-alveolar-cleft-examination-and-treatment-proposal-prior-to-bone-grafting-based-on-three-dimensional-versus-two-dimensional-diagnosis-a-diagnostic-study
#16
Susanne Wriedt, Bilal Al-Nawas, Irene Schmidtmann, Sami Eletr, Heinrich Wehrbein, Maximilian Moergel, Collin Jacobs
PURPOSE: The objective was to evaluate the diagnostic and prognostic value of three-dimensional (3D) cone beam computed tomography (CBCT) on information about the cleft and alignment of cleft neighboring teeth. MATERIALS AND METHODS: Panoramic X-rays, small-volume CBCTs, and study casts of 20 patients with a total of 22 alveolar clefts were analyzed prior to secondary bone grafting. Six maxillofacial surgeons and 6 orthodontists rated the following parameters: visibility of alveolar cleft expansion, position and probability of alignment of cleft neighbored teeth...
June 3, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28661082/centre-level-variation-of-treatment-and-outcome-in-5-year-old-children-with-non-syndromic-unilateral-cleft-lip-and-palate-the-cleft-care-uk-study-part-1-methodology-and%C3%A2-results-for-dento-facial-outcomes
#17
A K Wills, O Mahmoud, A Hall, D Sell, J Smallridge, L Southby, S Toms, A Waylen, Y Wren, A R Ness, J R Sandy
OBJECTIVES: Outline methods used to describe centre-level variation in treatment and outcome in children in the Cleft Care UK (CCUK) study. Report centre-level variation in dento-facial outcomes. SETTING AND SAMPLE POPULATION: Two hundred and sixty-eight five-year-old British children with non-syndromic unilateral cleft lip and palate (UCLP). MATERIALS AND METHODS: Between January 2011 and December 2012, data were collected on a comprehensive range of outcomes...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28661081/centre-level-variation-in-treatment-and-outcomes-and-predictors-of-outcomes-in-5-year-old-children-with-non-syndromic-unilateral-cleft-lip-treated-within-a-centralized-service-the-cleft-care-uk-study-part-6-summary-and-implications
#18
A R Ness, A K Wills, O Mahmoud, A Hall, D Sell, J Smallridge, L Southby, D Stokes, S Toms, A Waylen, Y Wren, J R Sandy
OBJECTIVES: To summarize and discuss centre-level variation across a range of treatment and outcome measures and examine individual and ecological determinants of outcome in children in Cleft Care UK (CCUK). SETTING AND SAMPLE POPULATION: Two hundred and sixty-eight 5-year-old British children with non-syndromic unilateral cleft lip and palate (UCLP) recruited to CCUK and treated within a centralized service. MATERIALS AND METHODS: Children had a range of treatment and outcome measures collected at a 5-year audit clinic...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28656723/stem-cell-therapy-for-reconstruction-of-alveolar-cleft-and-trauma-defects-in-adults-a-randomized-controlled-clinical-trial
#19
Mona N Bajestan, Archana Rajan, Sean P Edwards, Sharon Aronovich, Lucia H S Cevidanes, Angeliki Polymeri, Suncica Travan, Darnell Kaigler
BACKGROUND: Stem cell therapy with bone marrow-derived mesenchymal stem cells is a promising tissue engineering strategy to promote regeneration of craniofacial bone. PURPOSE: To determine whether cell therapy with ex vivo expanded stem cell populations would be safe and efficacious in the regeneration of large alveolar defects in patients with a history of cleft palate or craniofacial trauma. MATERIALS AND METHODS: Eighteen patients (10 patients with traumatic injury and 8 patients with cleft palate) presenting with missing teeth associated with horizontal alveolar bone deficiencies were included in this randomized controlled clinical trial...
June 28, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28653561/incidence-of-secondary-surgery-after-modified-furlow-palatoplasty-a-20-year-single-surgeon-case-series
#20
Stephen R Chorney, Emily Commesso, And Sherard Tatum
Objective To determine the occurrence of velopharyngeal insufficiency (VPI) requiring surgery and fistula repair after primary palatoplasty using a "modified" Furlow technique. Study Design Case series with chart review. Setting Academic multidisciplinary cleft and craniofacial center. Subjects and Methods Children younger than 18 years at presentation, with unrepaired cleft palate, with or without cleft lip, including submucous clefts, who underwent palatoplasty were included. No cleft patients having primary repair were excluded...
June 1, 2017: Otolaryngology—Head and Neck Surgery
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