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Chronic kidney disease and lung cancer

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https://www.readbyqxmd.com/read/27835923/ros-no-mediated-inter-organ-communication-in-skeletal-muscle-wasting-diseases
#1
Lucia Maria Leitner, Rebecca June Wilson, Zhen Yan, Axel Gödecke
SIGNIFICANCE: Cachexia is defined as a complex metabolic syndrome associated with underlying illness and a loss of muscle with or without loss of fat mass. This disease is associated with high incidence with chronic diseases such as heart failure, cancer, chronic obstructive pulmonary disease, AIDS, among others. Since there is currently no effective treatment available, cachectic patients have a poor prognosis. Elucidation of the underlying mechanisms is therefore an important medical task...
November 11, 2016: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/27771930/cddo-and-its-role-in-chronic-diseases
#2
Bryan J Mathis, Taixing Cui
There has been a continued interest in translational research focused on both natural products and manipulation of functional groups on these compounds to create novel derivatives with higher desired activities. Oleanolic acid, a component of traditional Chinese medicine used in hepatitis therapy, was modified by chemical processes to form 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO). This modification increased anti-inflammatory activity significantly and additional functional groups on the CDDO backbone have shown promise in treating conditions ranging from kidney disease to obesity to diabetes...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27423906/the-epidemiology-and-clinical-spectrum-of-melioidosis-in-a-teaching-hospital-in-a-north-eastern-state-of-malaysia-a-fifteen-year-review
#3
AbdelRahman Zueter, Chan Yean Yean, Mahmoud Abumarzouq, Zaidah Abdul Rahman, Zakuan Z Deris, Azian Harun
BACKGROUND: Over the last two decades, many epidemiological studies were performed to describe risks and clinical presentations of melioidosis in endemic countries. METHODS: We performed a retrospective analysis of 158 confirmed cases of melioidosis collected from medical records from 2001 to 2015 in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, in order to update the current status of melioidosis clinical epidemiology in this putatively high risk region of the country...
July 16, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27355220/-the-offer-of-medical-diagnostic-self-tests-on-german-language-websites-results-of-a-systematic-internet-search
#4
P Kuecuekbalaban, S Schmidt, H Muehlan
Aim of the study: The aim of the current study was to provide an overview of medical-diagnostic self-tests which can be purchased without a medical prescription on German language websites. Method: From September 2014 to March 2015, a systematic internet research was conducted with the following search terms: self-test, self-diagnosis, home test, home diagnosis, quick test, rapid test. Results: 513 different self-tests for the diagnostics of 52 diverse diseases or health risks were identified, including chronic diseases (e...
June 29, 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/27350012/mortality-of-lead-smelter-workers-a-follow-up-study-with-exposure-assessment
#5
Stephen J Bertke, Everett J Lehman, Steven J Wurzelbacher, Misty J Hein
BACKGROUND: Lead exposure has been linked to impaired renal function and kidney failure. High lead exposures have been associated with increased mortality from certain cancers, hypertension, cardiovascular disease, and amyotrophic lateral sclerosis (ALS). METHODS: We extended vital status follow-up on a cohort of 1,990 lead smelter workers by 25 years and computed standardized mortality ratios and rate ratios (RR) stratified by cumulative lead exposure. RESULTS: The update added 13,823 person-years at risk and 721 deaths...
June 28, 2016: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/27239422/cachexia-research-in-japan-facts-and-numbers-on-prevalence-incidence-and-clinical-impact
#6
EDITORIAL
Masaaki Konishi, Junichi Ishida, Jochen Springer, Stefan D Anker, Stephan von Haehling
Even though most clinical data on cachexia have been reported from Western countries, cachexia may be a growing problem in Asia as well, as the population in this area of the world is considerably larger. Considering the current definitions of obesity and sarcopenia in Japan, which are different from the ones in Western countries, the lack of a distinct cachexia definition in Japan is strinking. Only one epidemiological study has reported the prevalence of cachexia using weight loss as part of the definition in patients with stage III or IV non-small cell lung cancer...
December 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27229869/chronic-condition-clusters-and-functional-impairment-in-older-cancer-survivors-a-population-based-study
#7
Kelly M Kenzik, Erin E Kent, Michelle Y Martin, Smita Bhatia, Maria Pisu
PURPOSE: The purpose of the study is to identify chronic condition clusters at pre- and post-cancer diagnosis, evaluate predictors of developing clusters post-cancer, and examine the impact on functional impairment among older cancer survivors. METHODS: We identified 5991 survivors age 65 and older of prostate, breast, colorectal, lung, bladder, kidney, head and neck, and gynecologic cancer and non-Hodgkin lymphoma from the Surveillance, Epidemiology and End Results-Medicare Health Outcomes Survey resource...
December 2016: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/27133951/is-preoperative-anemia-a-risk-factor-for-upper-tract-urothelial-carcinoma-following-radical-nephroureterectomy
#8
Hsin-Chih Yeh, Tsu-Ming Chien, Wen-Jeng Wu, Ching-Chia Li, Wei-Ming Li, Hung-Lung Ke, Yii-Her Chou, Chii-Jye Wang, Shu-Pin Huang, Chien-Feng Li, Peir-In Liang, Chun-Nung Huang
PURPOSE: We aimed to identify the effect of preoperative anemia on oncologic outcomes in patients with upper tract urothelial carcinoma (UTUC) who had different levels of renal function. METHODS: Between 2000 and 2013, we enrolled 370 patients who underwent radical nephroureterectomy for nonmetastatic UTUC. Preoperative anemia was defined as hemoglobin <130g/l in men and <120g/l in women based on the World Health Organization classification. Kaplan-Meier method was applied to estimate the effect anemia on survival, and hazard ratios (HR) of anemia and other clinicopathological parameters were evaluated by Cox regression model...
August 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27118687/smoking-and-adverse-outcomes-in-patients-with-ckd-the-study-of-heart-and-renal-protection-sharp
#9
Natalie Staplin, Richard Haynes, William G Herrington, Christina Reith, Alan Cass, Bengt Fellström, Lixin Jiang, Bertram L Kasiske, Vera Krane, Adeera Levin, Robert Walker, Christoph Wanner, David C Wheeler, Martin J Landray, Colin Baigent, Jonathan Emberson
BACKGROUND: The absolute and relative importance of smoking to vascular and nonvascular outcomes in people with chronic kidney disease (CKD), as well its relevance to kidney disease progression, is uncertain. STUDY DESIGN: Observational study. SETTING & PARTICIPANTS: 9,270 participants with CKD enrolled in SHARP. PREDICTOR: Baseline smoking status (current, former, and never). OUTCOMES: Vascular events, site-specific cancer, ESRD, rate of change in estimated glomerular filtration rate (eGFR), and cause-specific mortality...
September 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27092943/association-of-kidney-disease-measures-with-cause-specific-mortality-the-korean-heart-study
#10
Yejin Mok, Kunihiro Matsushita, Yingying Sang, Shoshana H Ballew, Morgan Grams, Sang Yop Shin, Sun Ha Jee, Josef Coresh
BACKGROUND: The link of low estimated glomerular filtration rate (eGFR) and high proteinuria to cardiovascular disease (CVD) mortality is well known. However, its link to mortality due to other causes is less clear. METHODS: We studied 367,932 adults (20-93 years old) in the Korean Heart Study (baseline between 1996-2004 and follow-up until 2011) and assessed the associations of creatinine-based eGFR and dipstick proteinuria with mortality due to CVD (1,608 cases), cancer (4,035 cases), and other (non-CVD/non-cancer) causes (3,152 cases) after adjusting for potential confounders...
2016: PloS One
https://www.readbyqxmd.com/read/26811350/periodontal-disease-and-risk-of-all-cancers-among-male-never-smokers-an-updated-analysis-of-the-health-professionals-follow-up-study
#11
D S Michaud, K T Kelsey, E Papathanasiou, C A Genco, E Giovannucci
BACKGROUND: Periodontal disease has a direct impact on the immune response and has been linked to several chronic diseases, including atherosclerosis and stroke. Few studies have examined the association between periodontal disease and cancer. PATIENTS AND METHODS: A total of 19 933 men reported being never smokers (of cigarette, pipes or cigars) in the Health Professionals' Follow-up Study. Periodontal disease status and teeth number were self-reported at baseline and during follow-up...
May 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/26772444/meta-analysis-of-risks-for-short-term-readmission-in-patients-with-heart-failure
#12
REVIEW
Makoto Saito, Kazuaki Negishi, Thomas H Marwick
This investigation sought to quantify the risk factors for short-term readmission in patients with heart failure (HF). Electronic databases were systematically searched for studies reporting relative risk, odds ratio, and hazard ratio for the combined primary outcome of all-cause hospital readmission or all-cause mortality ≤90 days from discharge of patients with HF. Clinical characteristics, study design, type and incidence of outcome, univariable effect sizes for each risk factor, and their associated 95% confidence intervals were extracted...
February 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/26721908/comparative-pathology-of-aging-great-apes-bonobos-chimpanzees-gorillas-and-orangutans
#13
L J Lowenstine, R McManamon, K A Terio
The great apes (chimpanzees, bonobos, gorillas, and orangutans) are our closest relatives. Despite the many similarities, there are significant differences in aging among apes, including the human ape. Common to all are dental attrition, periodontitis, tooth loss, osteopenia, and arthritis, although gout is uniquely human and spondyloarthropathy is more prevalent in apes than humans. Humans are more prone to frailty, sarcopenia, osteoporosis, longevity past reproductive senescence, loss of brain volume, and Alzheimer dementia...
March 2016: Veterinary Pathology
https://www.readbyqxmd.com/read/26484028/transforming-growth-factor-%C3%AE-receptor-2-gene-polymorphisms-are-associated-with-end-stage-renal-disease
#14
Hye-Jin Ki, Se Yun Kim, Sang Ho Lee, Ju-Young Moon, Kyung Hwan Jeong, Tae Won Lee, Chun Gyoo Ihm, Su Kang Kim, Joo-Ho Chung, Sun Woo Kang, Tae Hee Kim, Yeong-Hoon Kim, Yang Gyun Kim
BACKGROUND: Transforming growth factor-beta (TGF-β) is a multifunctional cytokine involved in immune disorders, cancer, asthma, lung fibrosis, and chronic kidney disease, and its signal pathways are considered crucial mediators of a variety of cellular processes. In addition, several recent studies have reported that TGF-β receptor (TGF-βR) gene polymorphism is associated with chronic kidney disease. However, the association between end-stage renal disease (ESRD) and the TGF-β gene polymorphism has not been sufficiently investigated...
June 2015: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/26464424/analysis-of-heritability-and-shared-heritability-based-on-genome-wide-association-studies-for-thirteen-cancer-types
#15
Joshua N Sampson, William A Wheeler, Meredith Yeager, Orestis Panagiotou, Zhaoming Wang, Sonja I Berndt, Qing Lan, Christian C Abnet, Laufey T Amundadottir, Jonine D Figueroa, Maria Teresa Landi, Lisa Mirabello, Sharon A Savage, Philip R Taylor, Immaculata De Vivo, Katherine A McGlynn, Mark P Purdue, Preetha Rajaraman, Hans-Olov Adami, Anders Ahlbom, Demetrius Albanes, Maria Fernanda Amary, She-Juan An, Ulrika Andersson, Gerald Andriole, Irene L Andrulis, Emanuele Angelucci, Stephen M Ansell, Cecilia Arici, Bruce K Armstrong, Alan A Arslan, Melissa A Austin, Dalsu Baris, Donald A Barkauskas, Bryan A Bassig, Nikolaus Becker, Yolanda Benavente, Simone Benhamou, Christine Berg, David Van Den Berg, Leslie Bernstein, Kimberly A Bertrand, Brenda M Birmann, Amanda Black, Heiner Boeing, Paolo Boffetta, Marie-Christine Boutron-Ruault, Paige M Bracci, Louise Brinton, Angela R Brooks-Wilson, H Bas Bueno-de-Mesquita, Laurie Burdett, Julie Buring, Mary Ann Butler, Qiuyin Cai, Geraldine Cancel-Tassin, Federico Canzian, Alfredo Carrato, Tania Carreon, Angela Carta, John K C Chan, Ellen T Chang, Gee-Chen Chang, I-Shou Chang, Jiang Chang, Jenny Chang-Claude, Chien-Jen Chen, Chih-Yi Chen, Chu Chen, Chung-Hsing Chen, Constance Chen, Hongyan Chen, Kexin Chen, Kuan-Yu Chen, Kun-Chieh Chen, Ying Chen, Ying-Hsiang Chen, Yi-Song Chen, Yuh-Min Chen, Li-Hsin Chien, María-Dolores Chirlaque, Jin Eun Choi, Yi Young Choi, Wong-Ho Chow, Charles C Chung, Jacqueline Clavel, Françoise Clavel-Chapelon, Pierluigi Cocco, Joanne S Colt, Eva Comperat, Lucia Conde, Joseph M Connors, David Conti, Victoria K Cortessis, Michelle Cotterchio, Wendy Cozen, Simon Crouch, Marta Crous-Bou, Olivier Cussenot, Faith G Davis, Ti Ding, W Ryan Diver, Miren Dorronsoro, Laure Dossus, Eric J Duell, Maria Grazia Ennas, Ralph L Erickson, Maria Feychting, Adrienne M Flanagan, Lenka Foretova, Joseph F Fraumeni, Neal D Freedman, Laura E Beane Freeman, Charles Fuchs, Manuela Gago-Dominguez, Steven Gallinger, Yu-Tang Gao, Susan M Gapstur, Montserrat Garcia-Closas, Reina García-Closas, Randy D Gascoyne, Julie Gastier-Foster, Mia M Gaudet, J Michael Gaziano, Carol Giffen, Graham G Giles, Edward Giovannucci, Bengt Glimelius, Michael Goggins, Nalan Gokgoz, Alisa M Goldstein, Richard Gorlick, Myron Gross, Robert Grubb, Jian Gu, Peng Guan, Marc Gunter, Huan Guo, Thomas M Habermann, Christopher A Haiman, Dina Halai, Goran Hallmans, Manal Hassan, Claudia Hattinger, Qincheng He, Xingzhou He, Kathy Helzlsouer, Brian Henderson, Roger Henriksson, Henrik Hjalgrim, Judith Hoffman-Bolton, Chancellor Hohensee, Theodore R Holford, Elizabeth A Holly, Yun-Chul Hong, Robert N Hoover, Pamela L Horn-Ross, G M Monawar Hosain, H Dean Hosgood, Chin-Fu Hsiao, Nan Hu, Wei Hu, Zhibin Hu, Ming-Shyan Huang, Jose-Maria Huerta, Jen-Yu Hung, Amy Hutchinson, Peter D Inskip, Rebecca D Jackson, Eric J Jacobs, Mazda Jenab, Hyo-Sung Jeon, Bu-Tian Ji, Guangfu Jin, Li Jin, Christoffer Johansen, Alison Johnson, Yoo Jin Jung, Rudolph Kaaks, Aruna Kamineni, Eleanor Kane, Chang Hyun Kang, Margaret R Karagas, Rachel S Kelly, Kay-Tee Khaw, Christopher Kim, Hee Nam Kim, Jin Hee Kim, Jun Suk Kim, Yeul Hong Kim, Young Tae Kim, Young-Chul Kim, Cari M Kitahara, Alison P Klein, Robert J Klein, Manolis Kogevinas, Takashi Kohno, Laurence N Kolonel, Charles Kooperberg, Anne Kricker, Vittorio Krogh, Hideo Kunitoh, Robert C Kurtz, Sun-Seog Kweon, Andrea LaCroix, Charles Lawrence, Fernando Lecanda, Victor Ho Fun Lee, Donghui Li, Haixin Li, Jihua Li, Yao-Jen Li, Yuqing Li, Linda M Liao, Mark Liebow, Tracy Lightfoot, Wei-Yen Lim, Chien-Chung Lin, Dongxin Lin, Sara Lindstrom, Martha S Linet, Brian K Link, Chenwei Liu, Jianjun Liu, Li Liu, Börje Ljungberg, Josep Lloreta, Simonetta Di Lollo, Daru Lu, Eiluv Lund, Nuria Malats, Satu Mannisto, Loic Le Marchand, Neyssa Marina, Giovanna Masala, Giuseppe Mastrangelo, Keitaro Matsuo, Marc Maynadie, James McKay, Roberta McKean-Cowdin, Mads Melbye, Beatrice S Melin, Dominique S Michaud, Tetsuya Mitsudomi, Alain Monnereau, Rebecca Montalvan, Lee E Moore, Lotte Maxild Mortensen, Alexandra Nieters, Kari E North, Anne J Novak, Ann L Oberg, Kenneth Offit, In-Jae Oh, Sara H Olson, Domenico Palli, William Pao, In Kyu Park, Jae Yong Park, Kyong Hwa Park, Ana Patiño-Garcia, Sofia Pavanello, Petra H M Peeters, Reury-Perng Perng, Ulrike Peters, Gloria M Petersen, Piero Picci, Malcolm C Pike, Stefano Porru, Jennifer Prescott, Ludmila Prokunina-Olsson, Biyun Qian, You-Lin Qiao, Marco Rais, Elio Riboli, Jacques Riby, Harvey A Risch, Cosmeri Rizzato, Rebecca Rodabough, Eve Roman, Morgan Roupret, Avima M Ruder, Silvia de Sanjose, Ghislaine Scelo, Alan Schned, Fredrick Schumacher, Kendra Schwartz, Molly Schwenn, Katia Scotlandi, Adeline Seow, Consol Serra, Massimo Serra, Howard D Sesso, Veronica Wendy Setiawan, Gianluca Severi, Richard K Severson, Tait D Shanafelt, Hongbing Shen, Wei Shen, Min-Ho Shin, Kouya Shiraishi, Xiao-Ou Shu, Afshan Siddiq, Luis Sierrasesúmaga, Alan Dart Loon Sihoe, Christine F Skibola, Alex Smith, Martyn T Smith, Melissa C Southey, John J Spinelli, Anthony Staines, Meir Stampfer, Marianna C Stern, Victoria L Stevens, Rachael S Stolzenberg-Solomon, Jian Su, Wu-Chou Su, Malin Sund, Jae Sook Sung, Sook Whan Sung, Wen Tan, Wei Tang, Adonina Tardón, David Thomas, Carrie A Thompson, Lesley F Tinker, Roberto Tirabosco, Anne Tjønneland, Ruth C Travis, Dimitrios Trichopoulos, Fang-Yu Tsai, Ying-Huang Tsai, Margaret Tucker, Jenny Turner, Claire M Vajdic, Roel C H Vermeulen, Danylo J Villano, Paolo Vineis, Jarmo Virtamo, Kala Visvanathan, Jean Wactawski-Wende, Chaoyu Wang, Chih-Liang Wang, Jiu-Cun Wang, Junwen Wang, Fusheng Wei, Elisabete Weiderpass, George J Weiner, Stephanie Weinstein, Nicolas Wentzensen, Emily White, Thomas E Witzig, Brian M Wolpin, Maria Pik Wong, Chen Wu, Guoping Wu, Junjie Wu, Tangchun Wu, Wei Wu, Xifeng Wu, Yi-Long Wu, Jay S Wunder, Yong-Bing Xiang, Jun Xu, Ping Xu, Pan-Chyr Yang, Tsung-Ying Yang, Yuanqing Ye, Zhihua Yin, Jun Yokota, Ho-Il Yoon, Chong-Jen Yu, Herbert Yu, Kai Yu, Jian-Min Yuan, Andrew Zelenetz, Anne Zeleniuch-Jacquotte, Xu-Chao Zhang, Yawei Zhang, Xueying Zhao, Zhenhong Zhao, Hong Zheng, Tongzhang Zheng, Wei Zheng, Baosen Zhou, Meng Zhu, Mariagrazia Zucca, Simina M Boca, James R Cerhan, Giovanni M Ferri, Patricia Hartge, Chao Agnes Hsiung, Corrado Magnani, Lucia Miligi, Lindsay M Morton, Karin E Smedby, Lauren R Teras, Joseph Vijai, Sophia S Wang, Paul Brennan, Neil E Caporaso, David J Hunter, Peter Kraft, Nathaniel Rothman, Debra T Silverman, Susan L Slager, Stephen J Chanock, Nilanjan Chatterjee
BACKGROUND: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites. METHODS: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients...
December 2015: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/26450611/the-human-disease-network-in-terms-of-dysfunctional-regulatory-mechanisms
#16
Jing Yang, Su-Juan Wu, Wen-Tao Dai, Yi-Xue Li, Yuan-Yuan Li
BACKGROUND: Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug repositioning. In pioneer studies, disease similarity was commonly estimated according to clinical manifestation. Subsequently, scientists started to investigate disease similarity based on gene-phenotype knowledge, which were inevitably biased to well-studied diseases. In recent years, estimating disease similarity according to transcriptomic behavior significantly enhances the probability of finding novel disease relationships, while the currently available studies usually mine expression data through differential expression analysis that has been considered to have little chance of unraveling dysfunctional regulatory relationships, the causal pathogenesis of diseases...
2015: Biology Direct
https://www.readbyqxmd.com/read/26305139/chelation-therapy-for-treatment-of-systemic-intoxication-with-uranium-a-review
#17
REVIEW
Agnes Šömen Joksić, Sidney A Katz
Elevated levels of naturally occurring uranium have been found in small geographic areas throughout the world. Exposure of the general public to uranium is most often by the ingestion of food and water containing natural uranium from the hydrogeological environment, but this likelihood is remote. However, the risk is increased in regions where uranium is mined, milled, processed and/or fabricated as well as in the vicinity of former battlefields where depleted uranium munitions were deployed. Exposure in such cases is by the inhalation route...
2015: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/26233885/comparative-effectiveness-of-antiarrhythmic-drugs-for-rhythm-control-of-atrial-fibrillation
#18
Dingxin Qin, George Leef, Mian Bilal Alam, Rohit Rattan, Mohamad Bilal Munir, Divyang Patel, Furqan Khattak, Evan Adelstein, Sandeep K Jain, Samir Saba
INTRODUCTION: Although there are many different antiarrhythmic drugs (AADs) approved for rhythm management of atrial fibrillation (AF), little comparative effectiveness data exist to guide drug selection. METHODS: We followed 5952 consecutive AF patients who were prescribed amiodarone (N=2266), dronedarone (N=488), dofetilide (N=539), sotalol (N=1718), or class 1C agents (N=941) to the primary end point of AF recurrence. RESULTS: Median follow-up time was 18...
May 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/26131831/incidence-of-second-primary-malignancies-following-colorectal-cancer-a-distinct-pattern-of-occurrence-between-colon-and-rectal-cancers-and-association-of-co-morbidity-with-second-primary-malignancies-in-a-population-based-cohort-of-98-876-patients-in-taiwan
#19
Yu-Ting Lee, Chia-Jen Liu, Yu-Wen Hu, Chung-Jen Teng, Cheng-Hwai Tzeng, Chiu-Mei Yeh, Tzeng-Ji Chen, Jen-Kou Lin, Chun-Chi Lin, Yuan-Tzu Lan, Huann-Sheng Wang, Shung-Haur Yang, Jeng-Kai Jiang, Wei-Shone Chen, Tzu-Chen Lin, Shih-Ching Chang, Ming-Huang Chen, Hao-Wei Teng, Jin-Hwang Liu, Chueh-Chuan Yen
The purpose of this study is to determine the features of second primary malignancies (SPMs) among patients with prior colorectal cancer (CRC) using a nationwide population-based dataset.Patients with CRC newly diagnosed between 1996 and 2011, and >1 year of follow-up were recruited from the Taiwan National Health Insurance database. Standardized incidence ratios (SIRs) of SPMs in patients with CRC were calculated.During the 16-year study period, 4259 SPMs developed among 98,876 CRC patients. The median duration of follow-up was 4...
July 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26078926/surgical-treatment-for-non-small-cell-lung-cancer-in-patients-on-hemodialysis-due-to-chronic-kidney-disease-clinical-outcome-and-intermediate-term-results
#20
Byung Jo Park, Sumin Shin, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Young Mog Shim
BACKGROUND: Patients on dialysis undergoing surgery belong to a high-risk group. Only a few studies have evaluated the outcome of major thoracic surgical procedures in dialysis patients. We evaluated the outcomes of pulmonary resection for non-small cell lung cancer (NSCLC) in patients on hemodialysis (HD). METHODS: Between 2008 and 2013, seven patients on HD underwent pulmonary resection for NSCLC at our institution. We retrospectively reviewed their surgical outcomes and prognoses...
June 2015: Korean Journal of Thoracic and Cardiovascular Surgery
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