keyword
MENU ▼
Read by QxMD icon Read
search

iron reducing

keyword
https://www.readbyqxmd.com/read/28534830/calculation-of-haem-iron-intake-and-its-role-in-the-development-of-iron-deficiency-in-young-women-from-the-australian-longitudinal-study-on-women-s-health
#1
Angela J Reeves, Mark A McEvoy, Lesley K MacDonald-Wicks, Daniel Barker, John Attia, Allison M Hodge, Amanda J Patterson
Total iron intake is not strongly associated with iron stores, but haem iron intake may be more predictive. Haem iron is not available in most nutrient databases, so experimentally determined haem contents were applied to an Australian Food Frequency Questionnaire (FFQ) to estimate haem iron intake in a representative sample of young women (25-30 years). The association between dietary haem iron intakes and incident self-reported diagnosed iron deficiency over six years of follow-up was examined. Haem iron contents for Australian red meats, fish, and poultry were applied to haem-containing foods in the Dietary Questionnaire for Epidemiological Studies V2 (DQESv2) FFQ...
May 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28534724/maternal-protein-restriction-depresses-the-duodenal-expression-of-iron-transporters-and-serum-iron-level-in-male-weaning-piglets
#2
Wenqiang Ma, Jingyu Lu, Shuxia Jiang, Demin Cai, Shifeng Pan, Yimin Jia, Ruqian Zhao
To investigate the effects of maternal dietary protein restriction on offspring Fe metabolism, twenty-four second-parity Landrace×Yorkshire sows were randomly allocated to standard-protein (SP) and low-protein (LP) groups. The SP sows were fed diets containing 15 and 18 % crude protein throughout pregnancy and lactation, respectively, whereas the LP sows were subjected to 50 % dietary protein restriction. Offspring birth weight was not affected, but the body weight at weaning (P=0·06) and average daily gain (P=0·01) of the female piglets were significantly decreased...
April 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28534662/neuroprotection-of-brain-permeable-iron-chelator-vk-28-against-intracerebral-hemorrhage-in-mice
#3
Qian Li, Jieru Wan, Xi Lan, Xiaoning Han, Zhongyu Wang, Jian Wang
Iron overload plays a key role in the secondary brain damage that develops after intracerebral hemorrhage (ICH). The significant increase in iron deposition is associated with the generation of reactive oxygen species (ROS), which leads to oxidative brain damage. In this study, we examined the protective effects of VK-28, a brain-permeable iron chelator, against hemoglobin toxicity in an ex vivo organotypic hippocampal slice culture (OHSC) model and in middle-aged mice subjected to an in vivo, collagenase-induced ICH model...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28533366/mechanism-of-h2s-mediated-protection-against-oxidative-stress-in-escherichia-coli
#4
Alexander Mironov, Tatyana Seregina, Maxim Nagornykh, Lyly G Luhachack, Natalya Korolkova, Liubov Errais Lopes, Vera Kotova, Gennady Zavilgelsky, Rustem Shakulov, Konstantin Shatalin, Evgeny Nudler
Endogenous hydrogen sulfide (H2S) renders bacteria highly resistant to oxidative stress, but its mechanism remains poorly understood. Here, we report that 3-mercaptopyruvate sulfurtransferase (3MST) is the major source of endogenous H2S in Escherichia coli Cellular resistance to H2O2 strongly depends on the activity of mstA, a gene that encodes 3MST. Deletion of the ferric uptake regulator (Fur) renders ∆mstA cells hypersensitive to H2O2 Conversely, induction of chromosomal mstA from a strong pLtetO-1 promoter (P tet -mstA) renders ∆fur cells fully resistant to H2O2 Furthermore, the endogenous level of H2S is reduced in ∆fur or ∆sodA ∆sodB cells but restored after the addition of an iron chelator dipyridyl...
May 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28533164/a-novel-iron-ii-preferring-dopamine-agonist-chelator-d-607-significantly-suppresses-%C3%AE-syn-and-mptp-induced-toxicities-in-vivo
#5
Banibrata Das, Subramanian Rajagopalan, Gnanada S Joshi, Liping Xu, Dan Luo, Julie K Andersen, Sokol V Todi, Aloke K Dutta
Here, we report the characterization of a novel hybrid D2/D3 agonist and iron (II) specific chelator, D-607, as a multi-target-directed ligand against Parkinson's disease (PD). In our previously published report, we showed that D-607 is a potent agonist of dopamine (DA) D2/D3 receptors, exhibits efficacy in a reserpinized PD animal model and preferentially chelates to iron (II). As further evidence of its potential as a neuroprotective agent in PD, the present study reveals D-607 to be protective in neuronal PC12 cells against 6-OHDA toxicity...
May 19, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28530105/effect-of-humic-acid-on-the-removal-of-chromium-vi-and-the-production-of-solids-in-iron-electrocoagulation
#6
Chao Pan, Lyndsay D Troyer, Peng Liao, Jeffrey G Catalano, Wenlu Li, Daniel E Giammar
Iron-based electrocoagulation can be highly effective for Cr(VI) removal from water supplies. However, the presence of humic acid (HA) inhibited the rate of Cr(VI) removal in electrocoagulation, with the greatest decreases in Cr(VI) removal rate at higher pH. This inhibition was probably due to the formation of Fe(II) complexes with HA that are more rapidly oxidized than uncomplexed Fe(II) by dissolved oxygen, making less Fe(II) available for reduction of Cr(VI). Close association of Fe(III), Cr(III), and HA in the solid products formed during electrocoagulation influenced the fate of both Cr(III) and HA...
May 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28529645/tumor-penetrating-theranostic-nanoparticles-for-enhancement-of-targeted-and-image-guided-drug-delivery-into-peritoneal-tumors-following-intraperitoneal-delivery
#7
Ning Gao, Erica N Bozeman, Weiping Qian, Liya Wang, Hongyu Chen, Malgorzata Lipowska, Charles A Staley, Y Andrew Wang, Hui Mao, Lily Yang
The major obstacles in intraperitoneal (i.p.) chemotherapy of peritoneal tumors are fast absorption of drugs into the blood circulation, local and systemic toxicities, inadequate drug penetration into large tumors, and drug resistance. Targeted theranostic nanoparticles offer an opportunity to enhance the efficacy of i.p. therapy by increasing intratumoral drug delivery to overcome resistance, mediating image-guided drug delivery, and reducing systemic toxicity. Herein we report that i.p. delivery of urokinase plasminogen activator receptor (uPAR) targeted magnetic iron oxide nanoparticles (IONPs) led to intratumoral accumulation of 17% of total injected nanoparticles in an orthotopic mouse pancreatic cancer model, which was three-fold higher compared with intravenous delivery...
2017: Theranostics
https://www.readbyqxmd.com/read/28529107/is-there-a-role-for-preoperative-iron-supplementation-in-patients-preparing-for-a-total-hip-or-total-knee-arthroplasty
#8
Stephen M Petis, Brent A Lanting, Edward M Vasarhelyi, Douglas D R Naudie, Fiona E Ralley, James L Howard
BACKGROUND: Several treatment modalities exist for the treatment of perioperative anemia. We determined the effect of oral iron supplementation on preoperative anemia, and the use of blood-conserving interventions before total hip arthroplasty (THA) and total knee arthroplasty (TKA). METHODS: A total of 3435 total joint arthroplasties (1461 THAs and 1974 TKAs) were analyzed during 2 phases of a blood conservation program. The first phase used erythropoietin alfa (EPO) or intravenous (IV) iron for patients at risk for perioperative anemia...
April 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28528103/addition-of-exogenous-enzymes-to-diets-containing-grape-pomace-effects-on-intestinal-utilization-of-catechins-and-antioxidant-status-of-chickens
#9
S Chamorro, A Viveros, A Rebolé, I Arija, C Romero, I Alvarez, A Rey, A Brenes
Grape pomace (GP) is a rich source of polyphenols with antioxidant capacity. An experiment was conducted to study the effect of GP phenolic compounds included at 5 and 10%, and the addition (individually or combined) of hydrolyzing enzymes (carbohydrase enzyme complex and tannase at 500ppm) on intestinal utilization of catechins and antioxidant status in broiler chickens. A diet supplemented with 200ppm of α-tocopheryl acetate was also used. Our findings demonstrate the capacity of chickens to digest the monomeric (catechin, epicatechin, gallic acid, and epicatechin-O-gallate) and dimeric (procyanidin B1 and procyanidin B2) catechins present in grape pomace...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28527978/enhanced-antimony-v-removal-using-synergistic-effects-of-fe-hydrolytic-flocs-and-ultrafiltration-membrane-with-sludge-discharge-evaluation
#10
Baiwen Ma, Xing Wang, Ruiping Liu, Zenglu Qi, William A Jefferson, Huachun Lan, Huijuan Liu, Jiuhui Qu
The integration of adsorbents with ultrafiltration (UF) membranes is a promising method for alleviating membrane fouling and reducing land use. However, a number of problems have become apparent concerning the granular adsorbents used currently, such as high running cost, high chance of causing membrane surface damage, low in situ chemical cleaning efficiency, etc. Herein, to overcome these disadvantages, loose in situ hydrolyzed flocs were directly injected into the membrane tank, providing strong adsorption ability at low cost...
May 13, 2017: Water Research
https://www.readbyqxmd.com/read/28527388/abiotic-transformation-of-hexabromocyclododecane-by-sulfidated-nanoscale-zerovalent-iron-kinetics-mechanism-and-influencing-factors
#11
Dan Li, Xifen Zhu, Yin Zhong, Weilin Huang, Ping'an Peng
Recent studies showed that sulfidated nanoscale zerovalent iron (S-nZVI) is a better reducing agent than nanoscale zerovalen iron (nZVI) alone for reductive dechlorination of several organic solvents such as trichloroethylene (TCE) due to the catalytic role of iron sulfide (FeS). We measured the rates of transformation of hexabromocyclododecane (HBCD) by S-nZVI and compared them to those by FeS, nZVI, and reduced sulfur species. The results showed that: i) HBCD (20 mg L(-1)) was almost completely transformed by S-nZVI (0...
May 9, 2017: Water Research
https://www.readbyqxmd.com/read/28527339/selective-removal-of-toxic-cr-vi-from-aqueous-solution-by-adsorption-combined-with-reduction-at-a-magnetic-nanocomposite-surface
#12
Nazia H Kera, Madhumita Bhaumik, Kriveshini Pillay, Suprakas Sinha Ray, Arjun Maity
The adsorption of toxic hexavalent chromium (Cr(VI)) and its reduction to trivalent chromium (Cr(III)) are important processes for the treatment of industrial wastewater. Conducting polymers can adsorb and reduce Cr(VI) to less toxic Cr(III) but have low adsorption capacities due to agglomeration of particles and are difficult to separate from treated water. In this study, magnetic polypyrrole (PPy)-polyaniline (PANI)/iron oxide (Fe3O4) nanocomposite was synthesized for the selective removal of Cr(VI) in aqueous solution...
May 10, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28527212/apolipoprotein-e4-gender-body-mass-index-inflammation-insulin-resistance-and-air-pollution-interactions-recipe-for-alzheimer-s-disease-development-in-mexico-city-young-females
#13
Lilian Calderón-Garcidueñas, Suzanne M de la Monte
Given the epidemiological trends of increasing Alzheimer's disease (AD) and growing evidence that exposure and lifestyle factors contribute to AD risk and pathogenesis, attention should be paid to variables such as air pollution, in order to reduce rates of cognitive decline and dementia. Exposure to fine particulate matter (PM2.5) and ozone (O3) above the US EPA standards is associated with AD risk. Mexico City children experienced pre- and postnatal high exposures to PM2.5, O3, combustion-derived iron-rich nanoparticles, metals, polycyclic aromatic hydrocarbons, and endotoxins...
May 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28526432/quantitative-susceptibility-mapping-using-principles-of-echo-shifting-with-a-train-of-observations-sequence-on-1-5t-mri
#14
Hirohito Kan, Nobuyuki Arai, Harumasa Kasai, Hiroshi Kunitomo, Yasujiro Hirose, Yuta Shibamoto
PURPOSE: To evaluate the accuracy of susceptibility estimated from the principles of echo shifting with a train of observations (PRESTO) sequence using a 1.5T MRI system, we conducted experiments on the human brain using the PRESTO sequence and compared our results with the susceptibility obtained from spoiled gradient-recalled echo (GRE) sequence with flow compensation using quantitative susceptibility mapping (QSM) reconstruction. MATERIALS AND METHODS: Experiments on the human brain were conducted on 12 healthy volunteers (27±4years) using PRESTO and spoiled GRE sequences on a 1...
May 16, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28526387/adequacy-of-nutrient-intake-in-women-with-restrictive-anorexia-nervosa
#15
Chiara Chiurazzi, Iolanda Cioffi, Carmela De Caprio, Emilia De Filippo, Maurizio Marra, Rosa Sammarco, Maria Luisa Di Guglielmo, Franco Contaldo, Fabrizio Pasanisi
OBJECTIVE: The aim of the present study was to assess energy and nutrient intake in a group of women with restrictive AN (r-AN) compared with a control group. METHODS: Thirteen r-AN patients and 13 healthy female controls completed 7-d food records. Intake of macro- and micronutrients was compared between the two groups as well as to the Dietary Reference Intake for the Italian Population (LARN) for specific ages. Additionally, the r-AN patients underwent indirect calorimetry for measuring resting energy expenditure (REE)...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28522005/biocompatible-microcrystalline-cellulose-particles-from-cotton-wool-and-magnetization-via-a-simple-in-situ-co-precipitation-method
#16
Mehnaz Rashid, Mohammad Abdul Gafur, Mostafa Kaiyum Sharafat, Hideto Minami, Mohd Abdul Jalil Miah, Hasan Ahmad
This investigation describes the preparation of magnetically doped degradable microcrystalline cellulose (MCC) nanocomposite particles with application potential in biotechnology, solid support for biomolecule/water purification, oil recovery from water and beyond. MCC was first extracted from cotton wool, the most abundant biocompatible polymer, by sulfuric acid hydrolysis and the effect of acid strength was examined. The size of the elongated fiber structure was reduced with increasing acid strength. MCC particles extracted by treatment with 70% sulfuric acid were used to prepare magnetic MCC nanocomposite particles...
August 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28521818/in-vivo-evaluation-of-microglia-activation-by-intracranial-iron-overload-in-central-pain-after-spinal-cord-injury
#17
Fan Xing Meng, Jing Ming Hou, Tian Sheng Sun
BACKGROUND: Central pain (CP) is a common clinical problem in patients with spinal cord injury (SCI). Recent studies found the pathogenesis of CP was related to the remodeling of the brain. We investigate the roles of iron overload and subsequent microglia activate in the remodeling of the brain after SCI. METHODS: An SCI-induced CP model was established in Sprague-Dawley rats that were randomly assigned to SCI, sham operation, deferoxamine (DFX), minocycline, and nitric oxide synthase inhibitor treatment groups...
May 18, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28516947/artificial-local-magnetic-field-inhomogeneity-enhances-t2-relaxivity
#18
Zijian Zhou, Rui Tian, Zhenyu Wang, Zhen Yang, Yijing Liu, Gang Liu, Ruifang Wang, Jinhao Gao, Jibin Song, Liming Nie, Xiaoyuan Chen
Clustering of magnetic nanoparticles (MNPs) is perhaps the most effective, yet intriguing strategy to enhance T2 relaxivity in magnetic resonance imaging (MRI). However, the underlying mechanism is still not fully understood and the attempts to generalize the classic outersphere theory from single particles to clusters have been found to be inadequate. Here we show that clustering of MNPs enhances local field inhomogeneity due to reduced field symmetry, which can be further elevated by artificially involving iron oxide NPs with heterogeneous geometries in terms of size and shape...
May 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28515324/the-diferric-tyrosyl-radical-cluster-of-ribonucleotide-reductase-and-cytosolic-iron-sulfur-clusters-have-distinct-and-similar-biogenesis-requirements
#19
Haoran Li, Martin Stümpfig, Caiguo Zhang, Xiuxiang An, JoAnne Stubbe, Roland Lill, Mingxia Huang
How each metalloprotein assembles the correct metal at the proper binding site presents challenges to the cell. The di-iron enzyme ribonucleotide reductase (RNR) uses a diferric-tyrosyl radical (Fe(III)2-Y·) cofactor to initiate nucleotide reduction. Assembly of this cofactor requires O2, Fe(II), and a reducing equivalent. Recent studies show that RNR cofactor biosynthesis shares the same source of iron, in the form of [2Fe-2S]-GSH2 from the monothiol glutaredoxin Grx3/4, and the same electron source, in the form of the Dre2-Tah18 electron transfer chain, with the cytosolic iron-sulfur protein assembly (CIA) machinery required for maturation of [4Fe-4S] clusters in cytosolic and nuclear proteins...
May 17, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28514321/patient-blood-management-in-major-orthopedic-surgery-less-erythropoietin-and-more-iron
#20
Emmanuel Rineau, Alexandra Stoyanov, Emmanuel Samson, Laurent Hubert, Sigismond Lasocki
Erythropoietin (EPO) is proposed preoperatively to reduce blood transfusion in anemic patients (hemoglobin < 13 g/dL) scheduled for a major orthopedic surgery. New intravenous iron formulations allow infusion of higher doses, increasing EPO response. In that context, we evaluated in a before-after study (n = 62 and 65 patients for each period) a new EPO administration protocol (2 injections 4 and 3 weeks before surgery, and a third if hemoglobin <13 g/dL instead of <15 g/dL 2 weeks before surgery)...
May 12, 2017: Anesthesia and Analgesia
keyword
keyword
59820
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"