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Edoardo Fabini, Giovana Maria Lanchoti Fiori, Daniele Tedesco, Norberto Peporine Lopes, Carlo Bertucci
Cucurbitacins are a group of tetracyclic triterpenoids, known for centuries for their anti-cancer and anti-inflammatory properties, which are being actively investigated over the past decades in order to elucidate their mechanism of action. In perspective of being used as therapeutic molecules, a pharmacokinetic characterization is crucial to assess the affinity toward blood carrier proteins and extrapolate distribution volumes. Usually, pharmacokinetic data are first collected on animal models and later translated to humans; therefore, an early characterization of the interaction with carrier proteins from different species is highly desirable...
April 15, 2016: Journal of Pharmaceutical and Biomedical Analysis
Fagen Wang, Haojie Zhang, Dannong He
The CO catalytic oxidation at ambient temperature and high space velocity was studied over the Pd-Cu/MOx (MOx = TiO2 and AI203) catalysts. The higher Brunauer-Emmett-Teller area surface of the A1203 support facilitates the dispersion of Pd2+ species, and the presence of Cu2Cl(OH)3 accelerates the re-oxidation of Pd0 to Pd2+ over the Pd-Cu/Al203 catalyst, which contributed to better performance of CO catalytic oxidation. The poorer activity of the Pd-Cu/TiO2 catalyst was attributed to the lower dispersion of Pd2+ species because of the less surface area and the non-formation of Cu2CI(OH)3 species...
January 2014: Environmental Technology
Hui Yang, Zhi-Hong Liu
Novel Cu2O-CuCl composite thin film constructed by Cu2O nanoplates growing on the CuCI matrix was prepared under facile hydrothermal conditions at 120 degrees C. The phases and morphologies of the as-prepared products were characterized by energy dispersive X-ray spectroscopy (EDS), X-ray powder diffraction (XRD) and scanning electron microscopy (SEM). The result indicated that the thickness of Cu2O nanoplates was about 100 nm. Furthermore, the photocatalytic activity of the prepared Cu2O-CuCl composite thin film for the degradation of methyl orange was investigated by UV-vis spectrophotometer, demonstrating that it possessed the higher activity...
June 2011: Journal of Nanoscience and Nanotechnology
Irena Velcheva, Nadia Antonova, Petar Damianov, Nikolay Dimitrov
The aim of the study was to investigate the changes of the common carotid local hemodynamic factors like wall shear stress and tensile forces in 16 patients with chronic unilateral cerebral infarctions (CUCI), 58 patients with risk factors (RF) for cerebrovascular disease (CVD) and 25 healthy control subjects. The blood flow velocities (BFV), the internal diameters (D) and the vessel wall intima-media thickness (IMT) in the common carotid arteries (CCA) were recorded with color duplex sonography. Systolic (SBP) and diastolic (DBP) blood pressure were measured and mean blood pressure (MBP) was calculated by the formula of Wiggers...
2010: Clinical Hemorheology and Microcirculation
W Winiarczyk, L Krause
No abstract text is available yet for this article.
August 1, 1982: Applied Optics
Y Cuci, H Hasar, M Yaman, U Ipek
No abstract text is available yet for this article.
December 2001: Bulletin of Environmental Contamination and Toxicology
Weigend, Wirth, Ahlrichs, Fenske
The silylated derivative of thiophosphoric acid (S)P(SSiMe3)3 is used as a convenient starting compound for the synthesis of multinuclear Cu and Au cluster complexes. (S)P(SSiMe3)3 reacts with CuCI/PPh3 and [AuCClPPh3] to give the following compounds: [Cu4(P2S6)(PPh3)4] (1), [Cu6(P2S6)Cl2-(PPh3)6] (2) and [Au4(P2S6)(PPh3)4](3). According to X-ray structure determination, these compounds contain P2S6(4-) ions, in which S atoms act as ligands for Cu+ and Au+ ions. Although 1 and 3 have the same stoichiometry, bonding of the metal ions to the P2S6 skeleton displays small but remarkable differences...
February 4, 2000: Chemistry: a European Journal
R T Parmley, S S Spicer, C J Alvarez
The Prussian blue reaction was evaluated at the ultrastructural level as a cytochemical method to identify ferric and ferrous iron in rat bone marrow and splenic macrophages. Satisfactory tissue preservation and staining were achieved after fixation for 1 hr in 3% glutaraldehyde and exposure for 30 min to Perls's ferrocyanide solution before routine osmication and embedding. The acid ferrocyanide solution formed cuboidal and irregular electron-opaque deposits which localized ferric iron in the macrophage siderosomes and hyaloplasm...
September 1978: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
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