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https://www.readbyqxmd.com/read/30004636/twin-to-twin-transfusion-syndrome-from-amniodrainage-to-laser
#1
Federico Prefumo, Eric Jauniaux
No abstract text is available yet for this article.
August 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29997513/near-to-one-s-heart-the-intimate-relationship-between-the-placenta-and-fetal-heart
#2
REVIEW
Emily J Camm, Kimberley J Botting, Amanda N Sferruzzi-Perri
The development of the fetal heart is exquisitely controlled by a multitude of factors, ranging from humoral to mechanical forces. The gatekeeper regulating many of these factors is the placenta, an external fetal organ. As such, resistance within the placental vascular bed has a direct influence on the fetal circulation and therefore, the developing heart. In addition, the placenta serves as the interface between the mother and fetus, controlling substrate exchange and release of hormones into both circulations...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29951938/towards-computer-assisted-ttts-laser-ablation-detection-for-workflow-segmentation-from-fetoscopic-video
#3
Francisco Vasconcelos, Patrick Brandão, Tom Vercauteren, Sebastien Ourselin, Jan Deprest, Donald Peebles, Danail Stoyanov
PURPOSE: Intrauterine foetal surgery is the treatment option for several congenital malformations. For twin-to-twin transfusion syndrome (TTTS), interventions involve the use of laser fibre to ablate vessels in a shared placenta. The procedure presents a number of challenges for the surgeon, and computer-assisted technologies can potentially be a significant support. Vision-based sensing is the primary source of information from the intrauterine environment, and hence, vision approaches present an appealing approach for extracting higher level information from the surgical site...
June 27, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29905131/when-is-it-appropriate-to-put-a-live-donor-at-risk-to-help-another-patient
#4
Anjay Khandelwal
This article considers the nature and scope of ethical decision making in monozygotic sibling (MZS) skin grafting. Although rare, identical twin-to-twin skin grafting has been reported with excellent survival rates in burn patients. Of 16 cases published to date, only a few address the ethical decision making process that is involved with monozygotic sibling skin grafting; this article discusses clinical indications and ethical challenges.
June 1, 2018: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29881553/a-case-of-mirror-syndrome-caused-by-hydrops-fetalis-after-fetoscopic-laser-photocoagulation
#5
Emi Kino, Yohei Maki, Masanao Ohhashi, Seishi Furukawa, Takatsugu Maeda, Hiroshi Sameshima
Fetoscopic laser photocoagulation (FLP) of placental anastomoses is a well-established procedure for twin-to-twin transfusion syndrome that improves fetal outcome with rare maternal complications. However, fetal hydrops can develop even after FLP, and mirror syndrome can occur, indicating that both the fetal and maternal courses should be monitored after FLP.
June 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29796818/differences-in-the-expression-of-tlr-2-nod2-and-nf-%C3%AE%C2%BAb-in-placenta-between-twins
#6
Łukasz Szylberg, Magdalena Bodnar, Anna Lebioda, Patrycja Krepska, Adam Kowalewski, Grzegorz Bręborowicz, Andrzej Marszałek
Dizygotic twins share the same type of genetic relationship as non-twin siblings. Whereas monozygotic (MZ) twins are considered to have identical genetic material, they still differ. There is a number of reasons for early MZ twin discordance, including differences in the in utero environment, stochasticity, genetic mosaicism, and epigenetic factors. During gestation, the efficient innate immune system is of utmost importance. Our study was based on immunohistochemical evaluation of the differences in innate immune protein expression (TLR-2, NOD2, and NF-κB) in the 95 placentas between twins...
May 23, 2018: Archivum Immunologiae et Therapiae Experimentalis
https://www.readbyqxmd.com/read/29765597/cancer-cell-transmission-via-the-placenta
#7
REVIEW
Mel Greaves, William Hughes
Cancer cells have a parasitic propensity in the primary host but their capacity to transit between individuals is severely restrained by two factors: a lack of a route for viable cell transfer and immune recognition in allogeneic, secondary recipients. Several examples of transmissible animal cancers are now recognised. In humans, the only natural route for transmission is via the haemochorial placenta which is permissive for cell traffic. There are three special examples of this occurring in utero : maternal to foetus, intraplacental twin to twin leukaemias and choriocarcinoma-extra-embryonic cells to mother...
2018: Evolution, Medicine, and Public Health
https://www.readbyqxmd.com/read/29758014/investigating-the-epigenetic-discrimination-of-identical-twins-using-buccal-swabs-saliva-and-cigarette-butts-in-the-forensic-setting
#8
Athina Vidaki, Vivian Kalamara, Elena Carnero-Montoro, Timothy D Spector, Jordana T Bell, Manfred Kayser
Monozygotic (MZ) twins are typically indistinguishable via forensic DNA profiling. Recently, we demonstrated that epigenetic differentiation of MZ twins is feasible; however, proportions of twin differentially methylated CpG sites (tDMSs) identified in reference-type blood DNA were not replicated in trace-type blood DNA. Here we investigated buccal swabs as typical forensic reference material, and saliva and cigarette butts as commonly encountered forensic trace materials. As an analog to a forensic case, we analyzed one MZ twin pair...
May 14, 2018: Genes
https://www.readbyqxmd.com/read/29704280/prediction-of-adverse-pregnancy-outcome-in-monochorionic-diamniotic-twin-pregnancies-complicated-by-selective-fetal-growth-restriction
#9
Caitriona Monaghan, Erkan Kalafat, Julia Binder, Baskaran Thilaganathan, Asma Khalil
OBJECTIVE: To identify key factors implicated in adverse perinatal outcome in monochorionic twin pregnancies complicated by selective fetal growth restriction. METHODS: This is a retrospective cohort study conducted in a single tertiary referral centre included all monochorionic diamniotic (MCDA) twin pregnancies complicated by selective fetal growth restriction (sFGR). The presence of co-existing twin to twin transfusion syndrome (TTTS) was noted. Fetal biometry and Doppler indices, including the umbilical artery (UA) and ductus venosus (DV), were recorded at the time of diagnosis...
April 28, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29698746/for-submission-to-the-journal-of-gynaecology-obstetrics-and-human-reproduction
#10
Mélanie Korsakissok, Marion Groussolles, Odile Dicky, Corinne Alberge, Charlotte Casper, Corinne Azogui-Assouline
OBJECTIVE: To describe the morbidity and mortality and long-term neurodevelopmental outcomes in children born from a Twin-to-Twin Transfusion Syndrome (TTTS) pregnancy treated using laser fetoscopy in Toulouse. POPULATION AND METHOD: All pregnancies with TTTS treated by laser fetoscopy in our centre were included. Antenatal and postnatal morbidity and neonatal morbidity were identified in the medical records retrospectively. The neurodevelopmental outcome was studied using Ages and Stages Questionnaires (ASQ) sent to the parents, an oral interview with the parents and with the child's doctor (last objective neurological examination, rehabilitation needs, learning disabilities)...
April 23, 2018: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/29582948/-advances-in-fetal-therapy-in-complicated-monochorionic-pregnancies-and-in-severe-congenital-diaphragmatic-hernia-five-years-experience
#11
Yuval Gielchinsky, Dan V Valsky, Nili Yanai, Firas J Abdeljawad, Mazen A Muhaisen, Dan Arbell, Yehuda Ginosar, Orna Ben-Yosef, Orite Winograd, Benjamin Bar-Oz, Simcha Yagel, Smadar Eventov-Friedman
INTRODUCTION: : Minimally invasive fetal therapeutic procedures reduce the morbidity and mortality in monochorionic (MC) twins and in fetuses with congenital diaphragmatic hernia (CDH). MC pregnancies share their blood systems due to communicating vessels over their single placenta and may develop specific complications: Twin-to-Twin transfusion syndrome (TTTS), Selective intrauterine growth restriction (sIUGR), Twin Anemia-Polycythemia Sequence (TAPS), Twin Reverse Arterial Perfusion Syndrome (TRAP) or anomalies in one...
March 2018: Harefuah
https://www.readbyqxmd.com/read/29553462/harmony-behind-the-trumped-shaped-vessel-the-essential-role-of-the-ductus-venosus-in-fetal-medicine
#12
Sifa Turan, Ozhan M Turan
The ductus venosus is a fetal vessel that functions importantly in the transfer of oxygen-and nutrient-rich blood from the umbilical vein to vital organs. Its control under active regulation and its anatomy result in a flow-velocity profile that is typically forward throughout the cardiac cycle. This forward cardiac function reflects afterload, cardiac contractility, compliance, and vascular volume changes. Ductus venosus assessment gives valuable information under different fetal conditions. For example, during first trimester screening, an abnormal ductus venosus measurement changes the screening result...
March 15, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29546573/retrieval-and-registration-of-long-range-overlapping-frames-for-scalable-mosaicking-of-in-vivo-fetoscopy
#13
Loïc Peter, Marcel Tella-Amo, Dzhoshkun Ismail Shakir, George Attilakos, Ruwan Wimalasundera, Jan Deprest, Sébastien Ourselin, Tom Vercauteren
PURPOSE: The standard clinical treatment of Twin-to-Twin transfusion syndrome consists in the photo-coagulation of undesired anastomoses located on the placenta which are responsible to a blood transfer between the two twins. While being the standard of care procedure, fetoscopy suffers from a limited field-of-view of the placenta resulting in missed anastomoses. To facilitate the task of the clinician, building a global map of the placenta providing a larger overview of the vascular network is highly desired...
May 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29542428/a-possible-twin-the-1960s-twin-study-revisited-twin-research-twin-to-twin-heart-transplantation-distinguishing-monozygotic-twins-twin-conceptions-via-oocyte-donation-factors-affecting-craniofacial-traits-in-the-media-triplet-delivery-in-the-uk-conjoined-twins
#14
Nancy L Segal
This article begins with the story of a 51-year-old Los Angeles, California man, Justin Goldberg, whose daughter caught a glimpse of his striking look-alike at a popular market. Many people have so-called doppelgängers, but this occurrence is especially intriguing - the individual in question, born in New York City in the mid-1960s to an unwed mother, was an adoptee placed by the Louise Wise Adoption Agency. This agency, under the guidance of a prominent psychiatrist, decided to place twins in separate homes...
April 2018: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29487889/probabilistic-visual-and-electromagnetic-data-fusion-for-robust-drift-free-sequential-mosaicking-application-to-fetoscopy
#15
Marcel Tella-Amo, Loic Peter, Dzhoshkun I Shakir, Jan Deprest, Danail Stoyanov, Juan Eugenio Iglesias, Tom Vercauteren, Sebastien Ourselin
The most effective treatment for twin-to-twin transfusion syndrome is laser photocoagulation of the shared vascular anastomoses in the placenta. Vascular connections are extremely challenging to locate due to their caliber and the reduced field-of-view of the fetoscope. Therefore, mosaicking techniques are beneficial to expand the scene, facilitate navigation, and allow vessel photocoagulation decision-making. Local vision-based mosaicking algorithms inherently drift over time due to the use of pairwise transformations...
April 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29436718/fetal-doppler-changes-1-week-after-endoscopic-equatorial-laser-for-twin-to-twin-transfusion-syndrome-a-longitudinal-study
#16
Nicola Persico, Francesco D'Ambrosi, Isabella Fabietti, Simona Boito, Elisa Aiello, Alessandro Bulfoni, Fabrizio Ciralli, Alessandra Kustermann, Fabio Mosca, Luigi Fedele
OBJECTIVE: To investigate sequential Doppler changes in donors and recipients before and 1 week after endoscopic laser for twin-to-twin transfusion syndrome (TTTS) and to examine factors that may be associated with such changes. METHODS: In TTTS pregnancies undergoing laser treatment, we examined fetal Doppler changes before and 1 week postintervention. Intrauterine death rates and preoperative factors were analyzed in relation to Doppler changes. RESULTS: Among 129 (85...
April 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29417606/impact-of-laser-therapy-for-twin-to-twin-transfusion-syndrome-on-subsequent-pregnancy
#17
Maela Le Lous, Imen Mediouni, Gihad Chalouhi, Laurent J Salomon, Laurence Bussières, Aude Carrier, Jean-Pierre Bernard, Yves Ville
OBJECTIVES: The objective of our study was to determine the impact of laser therapy for twin-to-twin transfusion syndrome (TTTs) on subsequent pregnancies. METHODS: This was a monocentric retrospective observational study. Women treated by laser fetoscopy for TTTs were asked to answer a postal questionnaire about subsequent pregnancies. The primary outcome was fecundity (number of pregnancies and time to pregnancy). We also assessed pregnancy complications, birth weight, and gestational age at delivery...
March 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29381949/late-onset-transient-adrenal-insufficiency-in-preterm-twins-with-twin-to-twin-transfusion-syndrome-a-case-report
#18
Chin Yee Ho, Zong-Rong He, San-Nan Yang, Yung-Ning Yang
RATIONALE: Late-onset transient adrenal insufficiency with circulatory collapse is a rare condition that occurs in preterm infants. Although the incidence of late-onset transient adrenal insufficiency in preterm infants has been reported in Japan, reports from Western countries are lacking. In addition, no study has investigated the effect of twin-to-twin transfusion syndrome (TTTS) in monozygotic twins. PATIENT CONCERNS: A pair of extremely low birth weight twins presented with TTTS...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29353282/differential-changes-in-myocardial-performance-index-and-its-time-intervals-in-donors-and-recipients-of-twin-to-twin-transfusion-syndrome-before-and-after-laser-therapy
#19
Javier U Ortiz, Ximena Torres, Elisenda Eixarch, Mar Bennasar, Monica Cruz-Lemini, Olga Gómez, Silvia M Lobmaier, Josep M Martínez, Eduard Gratacós, Fatima Crispi
OBJECTIVE: To evaluate left myocardial performance index (MPI) and time intervals in fetuses with twin-to-twin transfusion syndrome (TTTS) before and after laser surgery. METHODS: Fifty-one fetal pairs with TTTS and 47 uncomplicated monochorionic twin pairs were included. Left ventricular isovolumetric contraction time (ICT), ejection time (ET), and isovolumetric relaxation time (IRT) were measured using conventional Doppler. RESULTS: Recipients showed prolonged ICT (46 ± 12 vs...
January 19, 2018: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29351779/the-effect-of-twin-to-twin-delivery-time-intervals-on-neonatal-outcome-for-second-twins
#20
L Lindroos, A Elfvin, L Ladfors, U-B Wennerholm
BACKGROUND: The objective was to examine the effect of twin-to-twin delivery intervals on neonatal outcome for second twins. METHODS: This was a retrospective, hospital-based study, performed at a university teaching hospital in Western Sweden. Twin deliveries between 2008 and 2014 at ≥32 + 0 weeks of gestation, where the first twin was delivered vaginally, were included. Primary outcome was a composite outcome of metabolic acidosis, Apgar < 4 at 5 min or peri/neonatal mortality in the second twin...
January 19, 2018: BMC Pregnancy and Childbirth
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