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post traumatic growth

Gül Ergün, Funda Gümüş, Gül Dikeç
AIM AND OBJECTIVES: To investigate the relationship between traumatic growth and psychological resilience in young adult children of parents with a mental disorder and to compare them with young adult children of parents without mental disorders. BACKGROUND: Negative life experiences that lead to trauma can affect young adults' psychological resilience, either positively or negatively. This study investigates levels of traumatic growth, the characteristics of psychological resilience, and the relationship between the former and latter in young adults between the ages of 18 and 23 who have parents with a mental disorder and who have parents without a mental disorder...
May 18, 2018: Journal of Clinical Nursing
Boris Sabirzhanov, Alan Faden, Taryn Aubrecht, Rebecca Henry, Ethan Glaser, Bogdan A Stoica
Angiopoietin-1 (Ang-1) is a well-known endothelial growth factor but its effects on neurons have yet to be elucidated. We show that Ang-1 is rapidly down-regulated in the injured brain after controlled cortical impact (CCI), a mouse experimental TBI model and in etoposide-induced neuronal apoptosis in vitro. Ang-1 treatment inhibits etoposide-induced up-regulation of pro-apoptotic Bcl-2 family members Noxa, Puma, Bim, and Bax; reduces markers of caspase-dependent (cytochrome c release/caspase activation) and caspase-independent (apoptosis-inducing factor release) pathways; and limits neuronal cell death...
May 18, 2018: Journal of Neurotrauma
Orli Thau-Zuchman, Rita Noutel Gomes, Simon Christopher Dyall, Meirion Davis, John V Priestley, Martine Groenendijk, Martijn DE Wilde, Jordi Lopez-Tremoleda, Adina T Michael-Titus
Traumatic brain injury (TBI) leads to cellular loss, destabilisation of membranes, disruption of synapses and altered brain connectivity, and increased risk of neurodegenerative disease. A significant and long-lasting decrease in phospholipids (PL), essential membrane constituents, has recently been reported in plasma and brain tissue, in human and experimental TBI. We hypothesised that supporting PL synthesis post-injury could improve outcome after TBI. We tested this hypothesis using a multi-nutrient combination designed to support the biosynthesis of phospholipids and available for clinical use...
May 17, 2018: Journal of Neurotrauma
Christoph Adler, Tobias Heller, Felix Schregel, Henning Hagmann, Martin Hellmich, Joana Adler, Hannes Reuter
BACKGROUND: Acute kidney injury (AKI) is a common complication after cardiopulmonary resuscitation (CPR) and predicts in-hospital mortality. To which extent post-resuscitation disease or the initial event of cardiac arrest and the duration of insufficient cardiac output triggers AKI is challenging to discriminate. Knowledge on molecular mediators of AKI is scarce. Early identification of patients at high risk of AKI is hampered by the low sensitivity of the established tests in clinical routine practice...
May 12, 2018: Critical Care: the Official Journal of the Critical Care Forum
A Casellas-Grau, E C Sumalla, M Lleras, J Vives, A Sirgo, C León, A Rodríguez, G Campos, Y Valverde, J M Borràs, C Ochoa
OBJECTIVE: Changes perceived as both positive (e.g., post-traumatic growth [PTG]) and negative (e.g. post-traumatic stress symptoms [PTSS]) have been associated with intensive internet use among breast cancer survivors. In this multi-center study, we analyzed the role of PTG and PTSS on the amount of time spent looking for online cancer information, its content, and its psychological impact. METHODS: PTSS and PTG were assessed in 182 breast cancer survivors using the Post-traumatic Stress Disorder Checklist and Post-traumatic Growth Inventory questionnaires...
May 8, 2018: Psycho-oncology
Yan-Ying Fan, Fang Nan, Bao-Lu Guo, Yan Liao, Ming-Sheng Zhang, Jie Guo, Bao-Long Niu, Yue-Qin Liang, Cai-Hong Yang, Yi Zhang, Xuan-Ping Zhang, Xue-Fen Pang
Glial scar impedes axon regeneration and functional recovery following traumatic brain injury (TBI). Although it has been shown that rapamycin (a specific inhibitor of mammalian target of rapamycin) can reduce astrocyte reactivation in the early stage of TBI, its effect on glial scar formation has not been characterized in TBI and other acute brain injury models. To test this, ICR mice received daily administration of rapamycin (0.5 or 1.5 mg/kg, i.p.) beginning at 1 h after cryogenic TBI (cTBI). The results showed that at 3 d post-injury, 1...
May 1, 2018: Neuroscience Letters
Deirdre M J Walsh, Ann Marie Groarke, Todd G Morrison, Garrett Durkan, Eamonn Rogers, Francis J Sullivan
PURPOSE: This study developed a measure of physical post traumatic growth (physical post traumatic growth inventory; P-PTGI) in men with prostate cancer. METHODS: A pool of items was created from themes identified in a qualitative study. A quantitative study was then conducted to assess the psychometric properties of the P-PTGI in a sample of 693 prostate cancer survivors. RESULTS: Tests of dimensionality revealed that the 20-item P-PTGI contained two factors: Health Autonomy and Health Awareness...
2018: PloS One
Paul J Read, Jon L Oliver, Mark B A De Ste Croix, Gregory D Myer, Rhodri S Lloyd
CONTEXT:   Despite the high frequency of knee injuries in athletes, few researchers have studied the effects of chronologic age and stage of maturation on knee-joint kinematics in male youth soccer players. OBJECTIVE:   To use a coach-friendly screening tool to examine knee-valgus scores for players of different ages and at different stages of maturation. DESIGN:   Cross-sectional study. SETTING:   Academy soccer clubs...
April 25, 2018: Journal of Athletic Training
Dusti R Jones, Jillian A Johnson, Jennifer E Graham-Engeland, Crystal L Park, Joshua M Smyth
BACKGROUND: Perceived growth (PG) refers to perceptions of positive changes that unfold over time after experiencing trauma. Higher PG is often associated with positive long-term health, but the processes through which PG may influence health are unclear. The present study examines two potential pathways among individuals living with asthma or RA: (1) by promoting momentary indicators of health and well-being in everyday life, and (2) by buffering against stress. METHOD: In a micro-longitudinal design, 128 participants with asthma (n = 97) or rheumatoid arthritis (n = 31) reported perceived growth using the Post-Traumatic Growth (PTG) Inventory and subsequently completed ecological momentary assessments (EMAs) for one week...
April 19, 2018: Applied Psychology. Health and Well-being
Richard Justin Garling, Lora Talley Watts, Shane Sprague, Murat Digicaylioglu
The mechanistic target of rapamycin (mTOR) is an intracellular protein kinase that functions as an energy and nutrient sensor in the cellular microenvironment of neurons. Modulation of mTOR is vital when nutrient and energy sources become limited. Hypoxia, traumatic brain injury, cellular energy states, and growth factors all regulate the phosphorylation and total levels of mTOR in cells. Alterations in the microenvironment induce transduction of signals to downstream proteins by mTOR allowing for cells to make the necessary adjustments to counteract stressors and survive...
March 2018: Neural Regeneration Research
Victoria Ross, Kairi Kõlves, Lisa Kunde, Diego De Leo
The death of a child by suicide is a severe trauma, placing parents at greater risk of psychological morbidity and physical health problems compared to other causes of death. However, few studies have examined the aftermath and bereavement experience for parents following the death of a child to suicide, limiting the ability to guide effective postvention services through empirical research. The current study, which was part of a larger longitudinal investigation of suicide bereavement in Queensland, Australia, examined the individual experiences of both mothers and fathers bereaved by suicide over time, specifically at the six month and 12 month time points after their loss...
March 28, 2018: International Journal of Environmental Research and Public Health
Ulrich Wesemann, Gerd D Willmund, Jörn Ungerer, Günter Kreim, Peter L Zimmermann, Antje Bühler, Michael Stein, Jakob Kaiser, Jens T Kowalski
Background: There are a high number of soldiers with deployment-related and non-deployment-related mental health problems in the German Armed Forces (Bundeswehr): This has led to an increase in mental disorders and a decrease in quality of life. To tackle these problems and to strengthen resources among the Bundeswehr personnel, this study aims at developing a screening instrument for assessing the psychological fitness of soldiers on the basis of questionnaire scales. In this approach, psychological fitness describes a soldier's ability to integrate and enhance his/her mental and emotional capabilities using resources and trainable skills...
March 27, 2018: Military Medicine
Elsa Mattson, Lisa James, Brian Engdahl
Introduction: Traumatic experiences can trigger negative effects such as post-traumatic stress disorder (PTSD). However, some individuals may also experience positive changes following trauma exposure. These changes are known as post-traumatic growth (PTG). Dispositional and situational factors are likely at play in determining both severity of PTSD symptoms and whether and to what degree an individual experiences PTG. This study examined how coping style and personality traits interact to influence PTSD and PTG...
March 26, 2018: Military Medicine
Shahram Bamdad, Aidin Meshksar, Mohammad Mostafa Safarpour
Endophthalmitis is one of the most serious complications of intraocular surgeries, and Candida albicans constitutes the majority of cases of post penetrating keratoplasty (PK) endophthalmitis. The presenting case is a 21-year-old woman with known case of advanced keratoconus and vernal keratoconjunctivitis who underwent PK, and developed recalcitrant anterior uveitis and subsequent whitish lesion on the superonasal of the lens. She was on topical steroids with possible impression of Uretts Zavalia syndrome versus phacoantigenic uveitis following traumatic cataract up to the 50th day of post operation that manifested symptoms of frank endophthalmitis; and underwent deep vitrectomy, lensectomy, localized iridectomy and irrigation with diluted Imipenem and Amphotericin-B...
January 2018: Electronic Physician
M Á Pérez-San-Gregorio, A Martín-Rodríguez, M Borda-Mas, M L Avargues-Navarro, J Pérez-Bernal, M Á Gómez-Bravo
OBJECTIVE: Analyze the influence of 2 variables (post-traumatic growth and time since liver transplantation) on coping strategies used by the transplant recipient's family members. METHODS: In all, 218 family members who were their main caregivers of liver transplant recipients were selected. They were evaluated using the Posttraumatic Growth Inventory and the Brief COPE. A 3 × 3 factorial analysis of variance was used to analyze the influence that post-traumatic growth level (low, medium, and high) and time since transplantation (≤3...
March 2018: Transplantation Proceedings
A Martín-Rodríguez, M Á Pérez-San-Gregorio, M L Avargues-Navarro, M Borda-Mas, J Pérez-Bernal, M Á Gómez-Bravo
OBJECTIVE: The aim of this work was to find out whether thinking frequently about the donor influences post-traumatic growth of liver transplant recipients. METHODS: The sample of 240 patients selected was made up of 185 men and 55 women with an overall mean age of 60.21 (SD 9.3) years. All of them had received liver transplants from cadaver donors. Transplant recipients were asked whether they thought frequently about the donor (yes or no) and filled out the Post-traumatic Growth Inventory...
March 2018: Transplantation Proceedings
S Loeffler, K Poehlmann, B Hornemann
This study aimed to explore individual meaning systems in the course of a breast cancer disease to test the assumed positive relation between meaning and well-being and to investigate the relationship between post-traumatic growth and well-being. A total of 65 patients with breast cancer were examined 1 year after initial treatment and another year follow-up. Questionnaires addressed meaning in life (MLQ), anxiety and depression (HADS), satisfaction with life (SWLS), health-related quality of life (EQ-5D, EORTC) and post-traumatic growth (PTGI)...
March 24, 2018: European Journal of Cancer Care
Parvaneh Hamidian, Nasrin Rezaee, Mansour Shakiba, Ali Navidian
Overcoming distresses and negative consequences of serious crises such as cancers can lead to perception of positive changes in the patients. It is necessary to design and test the psychological interventions that can improve post-traumatic growth. The objective of this study was to determine the effect of cognitive-emotional training on post-traumatic growth in women with breast cancer referred to the department of chemotherapy. This is a quasi-experimental study and it was performed on 85 patients with breast cancer who referred to an educational hospital in southeastern of Iran in 2017...
March 23, 2018: Journal of Clinical Psychology in Medical Settings
Safwat Y Diab, Sanna Isosävi, Samir R Qouta, Saija Kuittinen, Raija-Leena Punamäki
BACKGROUND: Women at pre partum and post partum are especially susceptible to war trauma because they struggle to protect their infants from danger. Trauma research suggests increased problems in maternal mental health and infant development. Yet many cognitive-emotional processes affect the trauma survivors' mental health, such as post-traumatic growth and post-traumatic cognition. The aim of this study was to examine whether a mother's high post-traumatic growth and optimal post-traumatic cognition could protect their own mental health and their infant's stress regulation from the effects of traumatic war experiences...
February 21, 2018: Lancet
Matthew Morin, Joshua Klatt, Peter M Stevens
Proximal tibial metaphyseal fractures in children can lead to progressive and symptomatic tibial valgus. Corrective osteotomy has been abandoned, due to frequent complications, including recurrent valgus deformity. While spontaneous remodelling has been reported, this is not predictable. For children with persistent deformities, we have resorted to guided growth of the tibia. We present 19 patients who were successfully treated with guided growth, tethering the proximal medial physis. There were ten boys and nine girls, ranging in age from two to 13...
March 16, 2018: Strategies in Trauma and Limb Reconstruction
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