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E V Rosseĭkin, E E Kobzev, O V Popyl'kova, S S Durmanov, V V Bazylev
Death in patients with postinfarction aneurysms of the left ventricle (LV) is mainly caused by life-threatening ventricular arrhythmias - ventricular tachycardias (VTs) and ventricular fibrillations (VFs). Surgical reconstruction of the LV may potentially lead to disruption of the re-entry mechanism, lying at the basis of ventricular tachyarrhythmias. A series of authors demonstrated high efficacy of such procedures as endocardectomy and radiofrequency ablation of the borderline zone of the LV. But high incidence of relapses, difficulty detecting the localization of VT and performing radiofrequency ablation (RFA), as well as high incidence of spontaneous and induced VTs in patients with postinfarction aneurysms of the LV have preserved dissatisfaction with the currently existing techniques...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
Ç Karaca, K-A Dere, N Er, A Aktaş, E Tosun, O-T Köseoğlu, A Usubütün
BACKGROUND: Odontogenic keratocysts have been reported with high recurrence rates in the literature so various treatment modalities from simple enucleation to resection have been performed to achieve the cure. The purpose of this retrospective study was to investigate the recurrence rate of odontogenic keratocysts (OKCs) treated by enucleation and peripheral ostectomy. MATERIAL AND METHODS: An electronic search of the database of the Hacettepe University, Faculty of Medicine, Department of Pathology, was undertaken to identify patients histologically diagnosed with OKCs treated at Department of Oral and Maxillofacial Surgery between 2001 and 2015...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
In-Bo Kim, Dong Wook Jung
BACKGROUND: Shoulder stiffness is a common complication after arthroscopic rotator cuff repair. However, there is no consensus on the treatment of stiffness after repair. Although one treatment option is an intra-articular steroid injection, it may negatively affect repair integrity, and there is a paucity of literature regarding the timing of intra-articular injections for stiffness after repair and its effect on repair integrity. PURPOSE: To compare repair integrity and clinical outcomes after an intra-articular steroid injection administered at 6 weeks and 12 weeks postoperatively for shoulder stiffness after arthroscopic rotator cuff repair...
June 1, 2018: American Journal of Sports Medicine
Shu-Jian Zheng, Shi-Jie Liu, Quan-Fei Zhu, Ning Guo, Ya-Lan Wang, Bi-Feng Yuan, Yu-Qi Feng
Chemical labeling (CL) in combination with liquid chromatography-mass spectrometry (LC-MS) analysis has been demonstrated to be a promising technology in metabolomic analysis. However, identification of chemically-labeled metabolites remains to be challenging. Retention time (RT) is one of the most important parameters for the identification of metabolites, but it could vary greatly in LC-MS analysis. In this work, we developed a chemical labeling-based HPLC retention index (CL-HPLC RI) strategy to facilitate the identification of metabolites...
June 20, 2018: Analytical Chemistry
Alejandro Rico-Guevara, Kristiina J Hurme
We propose a practical concept that distinguishes the particular kind of weaponry that has evolved to be used in combat between individuals of the same species and sex, which we term intrasexually selected weapons (ISWs). We present a treatise of ISWs in nature, aiming to understand their distinction and evolution from other secondary sex traits, including from 'sexually selected weapons', and from sexually dimorphic and monomorphic weaponry. We focus on the subset of secondary sex traits that are the result of same-sex combat, defined here as ISWs, provide not previously reported evolutionary patterns, and offer hypotheses to answer questions such as: why have only some species evolved weapons to fight for the opposite sex or breeding resources? We examined traits that seem to have evolved as ISWs in the entire animal phylogeny, restricting the classification of ISW to traits that are only present or enlarged in adults of one of the sexes, and are used as weapons during intrasexual fights...
June 20, 2018: Biological Reviews of the Cambridge Philosophical Society
Paul E Wischmeyer, Michelle M McMoon, Nathan H Waldron, Elizabeth J Dye
BACKGROUND: Enteral feeding via feeding tube (FT) provides essential nutrition support to critically ill patients or those who cannot intake adequate nutrition via the oral route. Unfortunately, 1%-2% of FTs placed blindly at bedside enter the airway undetected (as confirmed by x-ray), where they could result in adverse events. Misplaced FTs can cause complications including pneumothorax, vocal cord injury, bronchopleural fistula, pneumonia, and death. X-ray is typically performed to confirm FT placement before feeding, but may delay nutrition intake, may not universally identify misplacement, and adds cost and radiation exposure...
June 20, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Juliana Polizel Ocanha-Xavier, José Cândido Caldeira Xavier-Junior, Mariângela Esther Alencar Marques
BACKGROUND: The incidence of melanoma has been increasing in Brazil and all over the world. Despite improvements in diagnosis and treatment, mortality remains unchanged. OBJECTIVE: To associate clinical and histopathological aspects with the evolution of 136 cases of cutaneous melanoma. METHODS: Retrospective cohort study that analyzed all patients diagnosed with melanoma during the period from 2003 to 2011, with at least 4 years follow up...
June 2018: Anais Brasileiros de Dermatologia
Naoki Kato, Goichi Hashida, Kuni Konaka
Exercise for patients with amyotrophic lateral sclerosis (ALS) can be expected to improve function at the early stage of disease, but improvement cannot be expected at the late stage. However, no report has investigated the correlation between the effect of exercise and time since onset. This study examined the relevance between the effect of muscle strengthening exercise and time since onset in patients with ALS.This study is a retrospective nonconsecutive case series study at a single university hospital...
June 2018: Medicine (Baltimore)
Ju-Hyang Lee, Kyung In Woo, Yoon-Duck Kim
PURPOSE: Undercorrected blepharoptosis can be encountered after frontalis sling operation. Revision surgery for undercorrection has commonly involved introducing a new sling material. We describe and evaluate a simple surgical technique to correct undercorrection by adjusting preexisting fascia. METHODS: This is a retrospective interventional case series of patients undergoing sling revision between February 2010 and February 2017. Skin incision was made on the previous incision line...
June 18, 2018: Ophthalmic Plastic and Reconstructive Surgery
Judith Hellman, Soheyl Bahrami, Mihaly Boros, Irshad Chaudry, Gerhard Fritsch, Waldemar Gozdzik, Shigeaki Inoue, Peter Radermacher, Mervyn Singer, Marcin F Osuchowski, Markus Huber-Lang
As outlined in the "International Guidelines for Management of Sepsis and Septic Shock: 2016", initial fluid resuscitation and administration of antibiotics are key steps in the early management of sepsis and septic shock. However, such clear guidelines do not exist for pre-clinical sepsis models. To address these shortcomings, the Wiggers-Bernard conference on pre-clinical sepsis models was held in Vienna in May, 2017. The participants reviewed 260 of the most highly cited papers between 2003 and 2012 that used sepsis models...
June 19, 2018: Shock
Troy David Loeffler, Henry Chan, Badri Narayanan, Mathew J Cherukara, Stephen K Gray, Subramanian K R S Sankaranarayanan
Coarse-grained molecular dynamics (MD) simulations represent a powerful approach to simulate longer time scale and larger length scale phenomena than those accessible to all-atom models. The gain in efficiency, however, comes at the cost of atomistic details. The reverse transformation, also known as back-mapping, of coarse grained beads into their atomistic constituents represents a major challenge. Most existing approaches are limited to specific molecules or specific force-fields and often rely on running a long time atomistic MD of the back-mapped configuration to arrive at an optimal solution...
June 20, 2018: Journal of Physical Chemistry. B
Wei Chen, Ruiqing Fan, Ping Wang, Yuwei Dong, Yulin Yang
The chemistry of metal-organic frameworks has been progressing fast as its exciting potential multifunctional applications. Herein, serials of three-dimensional lanthanide-based metal-organic frameworks, {[Ln(HTPO)(NO3)-(H2O)]·x(CH3CN)·y(H2O)}n (Ln = Eu 1, Tb 2, Gd 3, Sm 4, Dy 5, Nd 6), {[Eu(TPO)(HCOO)0.5]·(H3O)0.5}n (7), {[Eu(TPO)(DMF)]·(solv)x}n (8) and {[Eu(TPO)(DMA)]·(solv)x}n (9) were synthesized with semi-rigid C3 symmetry ligand H3TPO. In these frameworks, ligand H3TPO presents totally different configuration, framework 1 exhibits good breathing properties for absorbing more guest molecules by solvent-induced single-crystal-to-single-crystal (SC-SC) transformation involving configuration transformation of organic linker in the framework...
June 20, 2018: Chemistry, An Asian Journal
Zhenghao Guo, Xia Wu, Jianhong Liu, Li Yao, Bin Hu
OBJECTIVE: Depression is a severe mental disorder. However, the neural mechanisms underlying affective interference (difficulties in directing attention away from negative distractors) in depression patients are still not well understood. In particular, the connections between brain regions remain unclear. Using the emotional face-word Stroop task, we aimed to reveal the altered electroencephalography (EEG) functional connectivity in patients with depression, using concepts from event-related potentials (ERPs) and time series clustering...
June 20, 2018: Journal of Neural Engineering
Yusuke Watanabe, Hiroshi Muraishi, Hideyuki Takei, Hidetake Hara, Tsuyoshi Terazaki, Nobuaki Shuto, Takahiro Shimo, Marika Nozawa, Hiromichi Ishiyama, Kazushige Hayakawa, Tsutomu Gomi
The transportation accuracy of sealed radioisotope sources influences the therapeutic effect of high-dose-rate (HDR) brachytherapy. We have developed a pinhole imaging system for tracking an Ir-192 radiation source during HDR brachytherapy treatment. Our system consists of a dual-pinhole collimator, a scintillator, and a charge-coupled device (CCD) camera. We acquired stereo-shifted images to infer the source position in three dimensions using a dual pinhole collimator with 1.0 mm diameter pinholes. The CCD camera captured consecutive images of scintillation light that corresponds to the source positions every 2 s...
June 20, 2018: Physics in Medicine and Biology
Viorel Circu, Laura F Chiriac, Iuliana Pasuk, Mihai Secu, Marin Micutz
A series of novel liquid crystals with various lanthanide ions (Eu(III), Sm(III) and Tb(III)) was designed and prepared starting from corresponding lanthanide nitrates and N-alkylated 4-pyridones derivatives with mesogenic 3,4,5-tris(alkyloxy)benzyl moieties (alkyl = hexyl, octyl, decyl, dodecyl, tetradecyl or hexadecyl). These new lanthanidomesogens were investigated for their mesogenic properties by a combination of differential scanning calorimetry (DSC), polarizing optical microscopy (POM) and temperature dependent powder X-ray diffraction (XRD)...
June 19, 2018: Chemistry: a European Journal
Yi Wang, Pramod Pandey, Yawen Zheng, Edward Robert Atwill, Gregory Pasternack
Improved understanding of pathogen survival in the stream environment is needed to enhance existing predictive models of stream pathogen populations. Further, the increasing use of thermal springs for bathing necessitates additional studies focused on not only typical streams but also thermal spring conditions, where water temperature is relatively higher than typical streams. This study was conducted to assess the survival of E. coli O157:H7 and Salmonella Typhimurium in stream water under free floating and particle-attached conditions at a range of temperature...
June 19, 2018: AMB Express
Michael C Honigberg, Nandita S Scott
PURPOSE OF REVIEW: To educate clinicians about the epidemiology, etiologies, diagnosis, and management of pregnancy-associated myocardial infarction (PAMI). RECENT FINDINGS: The risk of myocardial infarction is increased more than threefold around the time of pregnancy. In the recent series, PAMI is most commonly caused by spontaneous coronary artery dissection, followed by atherosclerosis. Percutaneous coronary intervention or coronary artery bypass grafting may be required, but conservative management with medical therapy is generally advised when possible, particularly in cases of coronary dissection...
June 19, 2018: Current Treatment Options in Cardiovascular Medicine
M W M Wintergerst, P P Larsen, B Heimes, D Pauleikhoff, F G Holz, R P Finger
BACKGROUND: Different injection regimens from continuous to pro re nata (PRN) have been proposed for treatment of neovascular age-related macular degeneration (nAMD). So far the PRN single injection on reactivation regimen has not been compared to the PRN triple injection on reactivation regimen (IVAN scheme). OBJECTIVE: Comparison of the two nAMD PRN injection regimens with single and triple injections on reactivation in a real-world setting in a retrospective case series in two German treatment centers...
June 19, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Ka Wai Kam, Anita Li, Rachel Pui Wai Kwok, Michael W Belin, Alvin L Young
PURPOSE: We aim to design two sampling methods, the grid and sectoral methods, to provide more precise detection of focal corneal scar changes with time following pterygium excision with the Pentacam imaging system. METHODS: This is a retrospective study of our previous prospective observational case series. Thirty patients underwent primary pterygium excision with adjuvant topical mitomycin-C application were followed up and imaged with Pentacam system at postoperative weeks 1, 4, 12 and month 18...
June 19, 2018: International Ophthalmology
Paola Caroli, Israel Sandler, Federica Matteucci, Ugo De Giorgi, Licia Uccelli, Monica Celli, Flavia Foca, Domenico Barone, Antonino Romeo, Anna Sarnelli, Giovanni Paganelli
PURPOSE: We studied the usefulness of 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT for detecting relapse in a prospective series of patients with biochemical recurrence (BCR) of prostate cancer (PCa) after radical treatment. METHODS: Patients with BCR of PCa after radical surgery and/or radiotherapy with or without androgen-deprivation therapy were included in the study. 68 Ga-PSMA PET/CT scans performed from the top of the head to the mid-thigh 60 min after intravenous injection of 150 ± 50 MBq of 68 Ga-PSMA were interpreted by two nuclear medicine physicians...
June 19, 2018: European Journal of Nuclear Medicine and Molecular Imaging
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