Read by QxMD icon Read


Richard Deth, Andrew Clarke, Jiayi Ni, Malav Trivedi
: This study reports the plasma glutathione concentrations in a double-blind, randomized, controlled, 2 × 2 cross-over study in which healthy participants consumed conventional milk (2 × 250 mL per day) containing both A1 and A2 types of β-casein, or milk containing only A2 type β-casein. Beta-casomorphin-7 (BCM-7), a peptide uniquely derived from the A1 type of β-casein, was previously reported to downregulate glutathione expression in human gut epithelial and neuronal cell lines by limiting cysteine uptake...
September 29, 2016: Nutrition Journal
Paik Seong Lim, Chang Hsu Chen, Fansan Zhu, Peter Kotanko, Yachung Jeng, Chun Yu Hu, Li Shu Chiu, Hui-Chen Chang
OBJECTIVE: Obesity is becoming increasingly common in hemodialysis (HD) patients and is associated with inflammation and increased mortality. The primary aim of the present study was to evaluate the accuracy and variability of the bioimpedance device in measuring body fat in Taiwanese dialysis patients. DESIGN: Cross-sectional study. SUBJECTS: One hundred twenty-two adult patients receiving HD in a single hospital in Taiwan. SETTING: We compared the results of fat mass (FM) measured by dual-energy x-ray absorptiometry (DEXA) and bioelectrical impedance spectroscopy device (Body composition monitor, BCM)...
September 22, 2016: Journal of Renal Nutrition
Elizabeth Oei, Klara Paudel, Annemarie Visser, Hazel Finney, Stanley L Fan
AIM: To study the relationship between overhydration (OH) in peritoneal dialysis (PD) patients and cardiac mortality. METHODS: OH, as measured by body composition monitor (BCM), is associated with increased mortality in dialysis patients. BCM has been used to guide treatment on the assumption that correcting OH will improve cardiac morbidity and mortality although data demonstrating causality that is reversible is limited. We wished to determine if OH in PD patients predicted cardiac mortality, and if there was a correlation between OH and cardiac troponin-T (cTnT) levels...
September 6, 2016: World Journal of Nephrology
Huliyeti Hasimu, Sergio Marchesini, Maurizio Canavari
Despite some similarities with developed countries, the growth of organic market in China seems to follow a different path. Thus, important questions are how Chinese urban consumers perceive organic food, and what are the main concepts associated to the organic attribute. We aimed at representing in graphic form the network of mental associations with the organic concept. We used an adapted version of the "Brand concept mapping" method to acquire, process, and draw individual concept networks perceived by 50 organic food consumers in Shanghai...
September 16, 2016: Appetite
Shao'e Sun, Qi Li, Lingfeng Kong, Hong Yu, Xiaodong Zheng, Ruihai Yu, Lina Dai, Yan Sun, Jun Chen, Jun Liu, Lehai Ni, Yanwei Feng, Zhenzhen Yu, Shanmei Zou, Jiping Lin
This study represents the first comprehensive molecular assessment of northwestern Pacific molluscs. In total, 2801 DNA barcodes belonging to 569 species from China, Japan and Korea were analyzed. An overlap between intra- and interspecific genetic distances was present in 71 species. We tested the efficacy of this library by simulating a sequence-based specimen identification scenario using Best Match (BM), Best Close Match (BCM) and All Species Barcode (ASB) criteria with three threshold values. BM approach returned 89...
2016: Scientific Reports
Chen Huan-Sheng, Chang Yeong-Chang, Hsieh Ming-Hsing, Tseng Fan-Lieh, Lin Chu-Cheng, Wu Tsai-Kun, Chen Hung-Ping, Hung Sze-Hung, Chiu Hsien-Chang, Lee Chia-Chen, Hou Chun-Cheng, Cheng Chun-Ting, Liou Hung-Hsiang, Lin Chun-Ju, Lim Paik-Seong
PURPOSE: Fluid management with body composition monitor based on bioimpedance spectroscopy (BCM-BIS) has been found to be beneficial for dialysis patients. We conducted a study to provide an algorithm for the determination of post-dialysis target weight (PDTW) and to evaluate whether this approach could improve clinical outcomes compared to patients who had PDTW decided clinically. METHODS: Two hundred and ninety-eight dialysis patients participated in this 1-year randomized controlled trial...
November 2016: International Urology and Nephrology
Nikolaus Kriegeskorte, Jörn Diedrichsen
High-resolution functional imaging is providing increasingly rich measurements of brain activity in animals and humans. A major challenge is to leverage such data to gain insight into the brain's computational mechanisms. The first step is to define candidate brain-computational models (BCMs) that can perform the behavioural task in question. We would then like to infer which of the candidate BCMs best accounts for measured brain-activity data. Here we describe a method that complements each BCM by a measurement model (MM), which simulates the way the brain-activity measurements reflect neuronal activity (e...
October 5, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
Inge van der Kroon, Lieke Joosten, Berthold A Nock, Theodosia Maina, Otto C Boerman, Maarten Brom, Martin Gotthardt
OBJECTIVE: Accurate assessment of the (111)In-exendin-3 uptake within the pancreas requires exact delineation of the pancreas, which is highly challenging by MRI and CT in rodents. In this study, the pancreatic tracer (99m)Tc-demobesin-4 was evaluated for accurate delineation of the pancreas to be able to accurately quantify (111)In-exendin-3 uptake within the pancreas. METHODS: Healthy and alloxan-induced diabetic Brown Norway rats were injected with the pancreatic tracer (99m)Tc-demobesin-4 ([(99m)Tc-N4-Pro(1),Tyr(4),Nle(14)]bombesin) and the beta cell tracer (111)In-exendin-3 ([(111)In-DTPA-Lys(40)]exendin-3)...
October 3, 2016: Molecular Pharmaceutics
Lina Čiaplinskienė, Birutė Žilaitienė, Rasa Verkauskienė, Rimantas Žalinkevičius, Žana Bumbulienė, Virginija Vanagienė, Johannes Bitzer
OBJECTIVES: The study investigated the effects on female sexual function of a progestogen-containing combined oral contraceptives (COCs) with an antiandrogenic profile taken in a continuous regimen. METHODS: In this prospective randomised single-institution study, 80 healthy women with a monogamous partner and an active sexual life were randomised into two groups for a period of 3 months. Women in the exposed group (n = 40) took a COCs containing 30 μg ethinylestradiol (EE) and 3 mg drospirenone (DRSP) in a 21/7 regimen...
October 2016: European Journal of Contraception & Reproductive Health Care
Sunil V Rao, Uwe Zeymer, Pamela S Douglas, Hussein Al-Khalidi, Jennifer A White, Jingyu Liu, Howard Levy, Victor Guetta, C Michael Gibson, Jean-Francois Tanguay, Paul Vermeersch, Jérôme Roncalli, Jaroslaw D Kasprzak, Timothy D Henry, Norbert Frey, Oscar Kracoff, Jay H Traverse, Derek P Chew, Jose Lopez-Sendon, Reinilde Heyrman, Mitchell W Krucoff
BACKGROUND: Bioabsorbable cardiac matrix (BCM) is a novel device that attenuates adverse left ventricular (LV) remodeling after large myocardial infarctions in experimental models. OBJECTIVES: This study aimed to analyze whether BCM, compared with saline control, would result in less LV dilation and fewer adverse clinical events between baseline and 6 months. METHODS: In an international, randomized, double-blind, controlled trial, 303 subjects with large areas of infarction despite successful primary percutaneous coronary intervention (PCI) of ST-segment elevation myocardial infarction (STEMI) were randomized 2:1 to BCM or saline injected into the infarct-related artery 2 to 5 days after primary PCI...
August 16, 2016: Journal of the American College of Cardiology
Muzamil Olamide Hassan, Raquel Duarte, Therese Dix-Peek, Ahmed Vachiat, Sagren Naidoo, Caroline Dickens, Sacha Grinter, Pravin Manga, Saraladevi Naicker
BACKGROUND: Fluid overload is common in chronic kidney disease (CKD) patients, potentially driving chronic inflammation and left ventricular dysfunction. We investigated the association between volume overload, chronic inflammation, and left ventricular dysfunction across subgroups of CKD patients. METHODS: The study included 160 participants, comprising peritoneal dialysis (PD), hemodialysis (HD), stage-3 CKD patients, and age- and sex-matched controls (40 in each group)...
August 10, 2016: Clinical Nephrology
S Małgorzewicz, A Dębska-Slizień, B Czajka, A Owczarzak, B Rutkowski
BACKGROUND: Increasing evidence shows that body mass may play a role in complications after kidney transplantation and influence graft and patient survival. The aim of this study was to analyze the association between graft function and both the body mass and adipokines (leptin, visfatin, adiponectin) in kidney transplant recipients. METHODS: We studied 183 kidney transplant recipients from the Department of Nephrology, Transplantology and Internal Disease, Medical University of Gdansk...
June 2016: Transplantation Proceedings
G Antunes, A C Roque, F M Simoes-de-Souza
Long-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca(2+)]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase A2, and the extracellular signal-regulated protein kinase pathway, and its expression comprises the reduction of the population of synaptic AMPA receptors. Recently, a stochastic computational model of these signalling processes demonstrated that, in single synapses, LTD is probabilistic and bistable...
2016: Scientific Reports
Marie T Dittmann, Kirsty J Hammond, Paul Kirton, David J Humphries, Les A Crompton, Sylvia Ortmann, Tom H Misselbrook, Karl-Heinz Südekum, Angela Schwarm, Michael Kreuzer, Christopher K Reynolds, Marcus Clauss
Enteric methane (CH4) production is a side-effect of herbivore digestion, but it is unknown whether CH4 itself influences digestive physiology. We investigated the effect of adding CH4 to, or reducing it in, the reticulorumen (RR) in a 4×4 Latin square experiment with rumen-fistulated, non-lactating cows, with four treatments: (i) control, (ii) insufflation of CH4 (iCH4), (iii) N via rumen fistula, (iv) reduction of CH4 via administration of bromochloromethane (BCM). DM intake (DMI), apparent total tract digestibility, digesta mean retention times (MRT), rumen motility and chewing activity, spot breath CH4 emission (CH4exhal, litre/kg DMI) as well as CH4 dissolved in rumen fluid (CH4RRf, µg/ml) were measured...
September 2016: British Journal of Nutrition
Yoshihiko Maehara, Eiji Oki, Hiroshi Saeki, Eriko Tokunaga, Hiroyuki Kitao, Makoto Iimori, Shinichiro Niimi, Yuki Kataoka, Yasunori Emi, Yoshihiro Kakeji, Hideo Baba, Tetsuhiko Shirasaka
5-fluorouracil(5-FU)therapy has advanced greatly over the past 50 years, achieving enhanced therapeutic effects and reduced adverse effects. By taking advantage of the metabolism of 5-FU, researchers have made efforts to develop prodrugs, combination drug products, and combination therapy regimens via biochemical modulation(BCM)with alteration of the drug metabolism. Examples include the advent of the prodrug tegafur(FT), followed by tegafur-uracil(UFT)and tegafurgimeracil- potassium oxonate(S-1)as combined products based on BCM...
July 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Masako Fujioka-Kobayashi, Jordi Caballé-Serrano, Dieter D Bosshardt, Reinhard Gruber, Daniel Buser, Richard J Miron
BACKGROUND: The use of autogenous bone chips during guided bone regeneration procedures has remained the gold standard for bone grafting due to its excellent combination of osteoconduction, osteoinduction and osteogenesis. Recent protocols established by our group have characterized specific growth factors and cytokines released from autogenous bone that have the potential to be harvested and isolated into bone conditioned media (BCM). Due to the advantageous osteo-promotive properties of BCM, the aims of the present study was to pre-coat collagen barrier membranes with BCM and investigate its effect on osteoblast adhesion, proliferation and differentiation for possible future clinical use...
2016: BMC Oral Health
Ahmet Ali Tuncer, Adnan Narcı, Fatma Hüsniye Dilek, Didem Baskın Embleton, Salih Çetinkurşun
BACKGROUND: Benign cystic mesothelioma (BCM) is a rare tumor with benign characteristic. There are only 8 child cases reported in the English literature. In this report, we present this rare entity a brief review of the literature. CASE REPORT: A two year-old boy presenting with abdominal swelling was hospitalized. Physical examination revealed a mass filling the abdomen. Laboratory findings were not specific. Abdominal computerized tomography showed a 15×13×11 cm cystic mass extending from the bladder to the liver with no solid components and no infiltration to adjacent organs...
March 2016: Balkan Medical Journal
Hyun Deok Shin, Suk Bae Kim
Benign cystic mesothelioma (BCM) is a rare benign disease that forms multicystic masses in the abdomen, pelvis, and retroperitoneum. It occurs predominantly in young to middle-aged women. The majority of cases were associated with a history of abdominal or pelvic operation, a history of endometriosis, and pelvic inflammatory disease. We present a unique case of BCM which is different to the previous cases. The patient was a 52-year-old man showing features of peritoneal carcinomatosis accompanied by ascites on abdominal computed tomography scans...
January 2016: Case Reports in Gastroenterology
Koji Sakamaki, Yuko Maejima, Yoshiharu Tokita, Yasuhiro Masamura, Kensuke Kumamoto, Masako Akuzawa, Nobuo Nagano, Katsuyuki Nakajima, Kenju Shimomura, Seiichi Takenoshita, Yohnosuke Shimomura
Objective The aim of this study was to examine the associations between the visceral fat area (VFA) and the subcutaneous fat area (SFA) as estimated by the dual impedance method with a body composition monitor (BCM) and the diagnostic components of metabolic syndrome in a middle-aged Japanese population. Methods The subjects included 303 men (average age 51.3±9.0 years old) and 345 women (average age 40.0±9.4 years old). The VFA and SFA were estimated by BCM, and the associations among the components of metabolic syndrome (waist circumference, blood pressure and related blood sample tests) were evaluated...
2016: Internal Medicine
Shuangshuang Guo, Tyler Gillingham, Yuming Guo, Di Meng, Weishu Zhu, William Allan Walker, Kriston Ganguli
OBJECTIVES: The secreted metabolites of probiotics are cytoprotective to intestinal epithelium and have been shown to attenuate inflammation and reduce gut permeability. This study was designed to determine the protective effects of probiotic conditioned media (PCM) from Bifidobacterium infantis (BCM) and Lactobacillus acidophilus (LCM) on IL-1β-induced intestinal barrier compromise. METHODS: The epithelial barrier was determined by measuring the transepithelial electrical resistance (TER) across a Caco-2 cell monolayer using a Transwell model...
June 17, 2016: Journal of Pediatric Gastroenterology and Nutrition
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"