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https://www.readbyqxmd.com/read/29150344/biomechanical-mechanism-of-lateral-trunk-lean-gait-for-knee-osteoarthritis-patients
#1
Kazuki Tokuda, Masaya Anan, Makoto Takahashi, Tomonori Sawada, Kenji Tanimoto, Nobuhiro Kito, Koichi Shinkoda
The biomechanical mechanism of lateral trunk lean gait employed to reduce external knee adduction moment (KAM) for knee osteoarthritis (OA) patients is not well known. This mechanism may relate to the center of mass (COM) motion. Moreover, lateral trunk lean gait may affect motor control of the COM displacement. Uncontrolled manifold (UCM) analysis is an evaluation index used to understand motor control and variability of the motor task. Here we aimed to clarify the biomechanical mechanism to reduce KAM during lateral trunk lean gait and how motor variability controls the COM displacement...
November 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29149953/myocardial-perfusion-scans-and-mortality-in-asymptomatic-patients-awaiting-renal-transplantation
#2
A Jauhal, S Harenberg, J J Crawford, I Bare, B Prasad, L Zahorski, G Ollenberger, V Trivedi, V Chopra, A Shoker, A Lavoie, P Dehghani
Cardiac risk assessment for asymptomatic patients awaiting renal transplantation is controversial. Patients awaiting renal transplantation in Southern Saskatchewan from 2005 to 2015 were retrospectively reviewed. Patients underwent cardiac risk stratification with stress myocardial perfusion scan. Baseline clinical characteristics, nuclear scan results, all-cause mortality, and cardiovascular events were analyzed. Abnormal scans were defined as studies with reversible defects, wall motion abnormalities, lung uptake, or transient ischemic dilation...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29149623/the-effect-of-surgical-approach-on-gait-mechanics-after-total-hip-arthroplasty
#3
Joseph Zeni, Kathleen Madara, Hunter Witmer, Riley Gerhardt, James Rubano
BACKGROUND: Few studies have compared the biomechanical outcomes of different surgical approaches for hip arthroplasty. The purpose of this study was to compare hip, pelvic, and trunk kinematics and kinetics between individuals who underwent a posterior or anterolateral approach. METHODS: Forty-five individuals between 40 and 80 years old underwent motion analysis during overground gait prior to hip arthroplasty and 3 months after surgery. Walking speed, hip flexion angle, hip extension angle, adduction angle and moment, trunk angle, trunk lean, and pelvis drop were compared between approaches...
November 10, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29149564/binding-thermodynamics-and-kinetics-calculations-using-chemical-host-and-guest-a-comprehensive-picture-of-molecular-recognition
#4
Zhiye Tang, Chia-En A Chang
Understanding the fine balance between changes of entropy and enthalpy and the competition between a guest and water molecules in molecular binding is crucial in fundamental studies and practical applications. Experiments provide measurements. However, illustrating the binding/unbinding processes gives a complete picture of molecular recognition not directly available from experiments, and computational methods bridge the gaps. Here, we investigated guest association/dissociation with β-cyclodextrin (β-CD) by using microsecond-timescale molecular dynamics (MD) simulations, post-analysis and numerical calculations...
November 17, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29149063/estimating-stair-running-performance-using-inertial-sensors
#5
Lauro V Ojeda, Antonia M Zaferiou, Stephen M Cain, Rachel V Vitali, Steven P Davidson, Leia A Stirling, Noel C Perkins
Stair running, both ascending and descending, is a challenging aerobic exercise that many athletes, recreational runners, and soldiers perform during training. Studying biomechanics of stair running over multiple steps has been limited by the practical challenges presented while using optical-based motion tracking systems. We propose using foot-mounted inertial measurement units (IMUs) as a solution as they enable unrestricted motion capture in any environment and without need for external references. In particular, this paper presents methods for estimating foot velocity and trajectory during stair running using foot-mounted IMUs...
November 17, 2017: Sensors
https://www.readbyqxmd.com/read/29148586/a-dynamic-ultrasound-simulation-of-a-pulsating-three-layered-cca-for-validation-of-2d-wall-motion-and-blood-velocity-estimation-algorithms
#6
Xiao Hu, Yufeng Zhang, Guanghui Cai, Kexin Zhang, Li Deng, Lian Gao, Suya Han, Jianhua Chen
PURPOSE: A dynamic ultrasound simulation model for the common carotid artery (CCA) with three arterial layers for validation of 2D wall motion and blood velocity estimation algorithms is proposed in present study. This model describes layers with not only characteristics of echo distributions conforming to clinical ones, but also varying thicknesses, axial and radial displacements with pulsatile blood pressure during a cardiac cycle. METHODS: The modeling process is as follows: first, a geometrical model according with the clinical structure size of a CCA is built based on the preset layer thicknesses and the diameter of lumen...
November 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/29148155/identifying-biomechanical-gait-parameters-in-adolescent-boys-with-haemophilia-using-principal-component-analysis
#7
L B Suckling, D Stephensen, M C Cramp, R Mahaffey, W I Drechsler
INTRODUCTION: Improvements in the medical management for those with haemophilia have resulted in improved clinical outcomes. However, current treatment regimens do not alleviate all joint haemarthroses with the potential for long-term joint deterioration remaining. The evaluation of functional activities such as gait, using standardized tools to monitor children with haemophilia is emerging. AIM: This study explored differences in sagittal plane biomechanics of walking in adolescent boys aged 11-18 years with haemophilia and an age-matched group of typically developing boys...
November 17, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29147941/artificial-bio-nanomachines-based-on-protein-needles-derived-from-bacteriophage-t4
#8
REVIEW
Hiroshi Inaba, Takafumi Ueno
Bacteriophage T4 is a natural bio-nanomachine which achieves efficient infection of host cells via cooperative motion of specific three-dimensional protein architectures. The relationships between the protein structures and their dynamic functions have recently been clarified. In this review we summarize the design principles for fabrication of nanomachines using the component proteins of bacteriophage T4 based on these recent advances. We focus on the protein needle known as gp5, which is located at the center of the baseplate at the end of the contractile tail of bacteriophage T4...
November 16, 2017: Biophysical Reviews
https://www.readbyqxmd.com/read/29147743/low-implant-migration-of-the-sigma-%C3%A2-medial-unicompartmental-knee-arthroplasty
#9
Daan Koppens, Maiken Stilling, Stig Munk, Jesper Dalsgaard, Søren Rytter, Ole Gade Sørensen, Torben Bæk Hansen
PURPOSE: The purpose of this study was to evaluate implant migration of the fixed-bearing Sigma(®) medial unicompartmental knee arthroplasty (UKA). UKA is a regularly used treatment for patients with medial osteoarthritis (OA) of the knee. UKA has a higher revision rate than total knee arthroplasty. Implant migration can be used as a predictor of implant loosening. METHODS: A prospective radiostereometric cohort study was performed. Forty-five patients with medial OA of the knee were included and received a cemented Sigma(®) UKA...
November 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29147742/varus-tibial-alignment-is-associated-with-greater-tibial-baseplate-migration-at-10%C3%A2-years-following-total-knee-arthroplasty
#10
Matthew G Teeter, Douglas D Naudie, Richard W McCalden, Xunhua Yuan, David W Holdsworth, Steven J MacDonald, Brent A Lanting
PURPOSE: To examine implant migration and articular behavior of primary total knee arthroplasty (TKA) at 10 years after index surgery and correlate to implant alignment. METHODS: Thirty-five patients underwent a cemented posterior stabilized total knee arthroplasty with a surgical objective of neutral alignment and were enrolled in a long-term radiostereometric analysis (RSA) study. At 10 years after surgery, patients were analyzed for implant migration using RSA as well as radiographic assessment of articular behavior at four positions of knee flexion...
November 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29147669/cervical-intervertebral-disc-degeneration-and-low-cervical-extension-independently-associated-with-a-history-of-stinger-syndrome
#11
Takayoshi Hakkaku, Koichi Nakazato, Koji Koyama, Karina Kouzaki, Kenji Hiranuma
Background: Stinger syndrome frequently occurs in athletes who compete in collision sports. Sharp pain and impairment of neck motion are major symptoms. Cervical intervertebral disc degeneration (CIDD) is also frequently observed in those who compete in collision sports. Purpose/Hypothesis: To investigate whether CIDD and neck functionality are related to a history of stinger syndrome. The hypothesis was that a significant relationship exists between CIDD and neck motion and a history of stinger syndrome in Japanese collegiate football players...
November 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29146510/relative-contributions-of-the-midcarpal-and-radiocarpal-joints-to-dart-thrower-s-motion-at-the-wrist
#12
Patrick M Kane, Bryan G Vopat, P Kaveh Mansuripur, Michael P Gaspar, Scott W Wolfe, Joseph J Crisco, Christopher Got
PURPOSE: To identify the relative contributions of the radiocarpal (RC) and midcarpal (MC) joints to dart-thrower's motion (DTM) of the wrist. METHODS: Six cadaveric upper extremities were fixed to a custom-designed loading jig allowing for pure moment-rotation analysis in 24 different directions of wrist motion. Each specimen was tested in 3 states: intact, simulated radiocarpal fusion (sRCF) and simulated pancarpal fusion (sPCF). Moments of ± 1.5 Nm were applied at each of 24 directions for each state and the resulting wrist rotation recorded...
November 14, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29146508/biomechanical-analysis-of-palmar-midcarpal-instability-and-treatment-by-partial-wrist-arthrodesis
#13
Sarah A Shiga, Frederick W Werner, Marc Garcia-Elias, Brian J Harley
PURPOSE: To create a biomechanical model of palmar midcarpal instability by selective ligament sectioning and to analyze treatment by simulated partial wrist arthrodesis. METHODS: Nine fresh-frozen cadaver arms were moved through 3 servohydraulic actuated motions and 2 passive wrist mobilizations. The dorsal radiocarpal, triquetrohamate, scaphocapitate, and scaphotrapeziotrapezoid ligaments were sectioned to replicate palmar midcarpal instability. Kinematic data for the scaphoid, lunate, and triquetrum were recorded before and after ligament sectioning and again after simulated triquetrohamate arthrodesis (TqHA) and radiolunate arthrodesis (RLA)...
November 14, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29146166/hip-dysplasia-prevalence-associated-findings-and-procedures-from-large-multicenter-arthroscopy-study-group
#14
Dean K Matsuda, Andrew B Wolff, Shane J Nho, John P Salvo, John J Christoforetti, Benjamin R Kivlan, Thomas J Ellis, Dominic S Carreira
PURPOSE: To report observational findings of patients with acetabular dysplasia undergoing hip arthroscopy. METHODS: We performed a comparative case series of multicenter registry patients from January 2014 to April 2016 meeting the inclusion criteria of isolated hip arthroscopy, a documented lateral center-edge angle (LCEA), and completion of preoperative patient-reported outcome measures. A retrospective analysis compared range of motion, intra-articular pathology, and procedures of patients with dysplasia (LCEA ≤25°) and patients without dysplasia (LCEA >25°)...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29146012/a-biomechanical-cadaveric-study-comparing-superior-capsule-reconstruction-using-fascia-lata-allograft-with-human-dermal-allograft-for-irreparable-rotator-cuff-tear
#15
Teruhisa Mihata, Christopher N H Bui, Masaki Akeda, Matthew A Cavagnaro, Michael Kuenzler, Alexander B Peterson, Michelle H McGarry, Yasuo Itami, Orr Limpisvasti, Masashi Neo, Thay Q Lee
BACKGROUND: Biomechanical and clinical success of the superior capsule reconstruction (SCR) using fascia lata (FL) grafts has been reported. In the United States, human dermal (HD) allograft has been used successfully for SCRs; however, the biomechanical characteristics have not been reported. METHODS: Eight cadaveric shoulders were tested in 5 conditions: (1) intact; (2) irreparable supraspinatus tear; (3) SCR using FL allograft with anterior and posterior suturing; (4) SCR using HD allograft with anterior and posterior suturing; and (5) SCR using HD allograft with posterior suturing...
December 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29145437/assessment-of-the-suitability-of-biodegradable-rods-for-use-in-posterior-lumbar-fusion-an-in-vitro-biomechanical-evaluation-and-finite-element-analysis
#16
Fon-Yih Tsuang, Yueh-Ying Hsieh, Yi-Jie Kuo, Chia-Hsien Chen, Feng-Huei Lin, Chen-Sheng Chen, Chang-Jung Chiang
Interbody fusion with posterior instrumentation is a common method for treating lumbar degenerative disc diseases. However, the high rigidity of the fusion construct may produce abnormal stresses at the adjacent segment and lead to adjacent segment degeneration (ASD). As such, biodegradable implants are becoming more popular for use in orthopaedic surgery. These implants offer sufficient stability for fusion but at a reduced stiffness. Tailored to degrade over a specific timeframe, biodegradable implants could potentially mitigate the drawbacks of conventional stiff constructs and reduce the loading on adjacent segments...
2017: PloS One
https://www.readbyqxmd.com/read/29145309/short-term-effects-of-sports-taping-on-navicular-height-navicular-drop-and-peak-plantar-pressure-in-healthy-elite-athletes-a-within-subject-comparison
#17
Taegyu Kim, Jong-Chul Park
Medial tibial stress syndrome (MTSS) is one of the most common exercise-induced leg pain. The navicular drop (ND) was identified as a risk factor for MTSS. This study aimed to evaluate the short-term effects of sports taping applied to the supporting lower leg during sitting, standing, walking, and jogging to restrict the ND in healthy elite athletes.Twenty-four healthy elite athletes without a history of exercise-induced pain or injuries in the lower limbs participated in this study (median age: 21.00 years; 1st--3rd quartiles; 19...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145042/relationship-of-t1-slope-with-loss-of-lordosis-and-surgical-outcomes-after-laminoplasty-for-cervical-ossification-of-the-posterior-longitudinal-ligament
#18
Masashi Miyazaki, Toshinobu Ishihara, Naoki Notani, Shozo Kanezaki, Hiroshi Tsumura
OBJECTIVE: T1 slope (T1S) has emerged as a predictor of kyphotic alignment change after laminoplasty. Although it was reported that patients with cervical ossification of the posterior longitudinal ligament (OPLL) and higher T1S had more pronounced lordotic curvature before surgery and higher loss of cervical lordosis after surgery, few studies have attempted to correlate these findings with clinical outcomes. We aimed to investigate the relationship of T1S with loss of cervical lordosis and surgical outcomes after laminoplasty for cervical OPLL...
November 13, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29144311/velocity-based-analysis-of-sediment-incipient-deposition-in-rigid-boundary-open-channels
#19
Hafzullah Aksoy, Mir Jafar Sadegh Safari, Necati Erdem Unal, Mirali Mohammadi
Drainage systems must be designed in a way to minimize undesired problems such as decrease in hydraulic capacity of the channel, blockage and transport of pollutants due to deposition of sediment. Channel design considering self-cleansing criteria are used to solve the sedimentation problem. Incipient deposition is one of the non-deposition self-cleansing design criteria that can be used as a conservative method for channel design. Experimental studies have been carried out in five different cross-section channels, namely trapezoidal, rectangular, circular, U-shape and V-bottom...
November 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29144123/the-sign-of-nmr-chemical-shift-difference-as-a-determinant-of-the-origin-of-binding-selectivity-elucidation-of-the-position-dependence-of-phosphorylation-in-ligands-binding-to-scribble-pdz1
#20
Gustav Sundell, Beat Vögeli, Ylva Ivarsson, Celestine Chi
The use of NMR chemical shift perturbation to monitor changes taking place around the binding site of a ligand-protein interaction is a routine and widely applied methodology in the field of protein biochemistry. Shifts are often acquired by titrating various concentrations of ligand to a fixed concentration of the receptor and may serve the purposes, amongst others, to determine affinity constants, locate binding surfaces, or differentiate between binding mechanisms. Shifts are quantified by the so-called combined chemical shift difference...
November 16, 2017: Biochemistry
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