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pregnancy nutritional factors

Kate S Collison, Angela Inglis, Sherin Shibin, Soad Saleh, Bernard Andres, Rosario Ubungen, Jennifer Thiam, Princess Mata, Futwan A Al-Mohanna
RATIONALE: Aspartame (L-aspartyl phenylalanine methyl ester) is a non-nutritive sweetener (NNS) approved for use in more than 6000 dietary products and pharmaceuticals consumed by the general public including adults and children, pregnant and nursing mothers. However a recent prospective study reported a doubling of the risk of being overweight amongst 1-year old children whose mothers consumed NNS-sweetened beverages daily during pregnancy. We have previously shown that chronic aspartame (ASP) exposure commencing in utero may detrimentally affect adulthood adiposity status, glucose metabolism and aspects of behavior and spatial cognition, and that this can be modulated by developmental N-methyl-D-aspartate receptor (NMDAR) blockade with the competitive antagonist CGP 39551 (CGP)...
2018: PloS One
Rafał Kocyłowski, Iwona Lewicka, Mariusz Grzesiak, Zuzanna Gaj, Anna Sobańska, Joanna Poznaniak, Constantin von Kaisenberg, Joanna Suliburska
PURPOSE: To evaluate the dietary intake of pregnant women and their nutritional status of Ca, Mg, Fe, Zn, and Cu, as the nutritional status of pregnant women is an important factor for the proper progression of a pregnancy and the development and health of the foetus. METHODS: The study was conducted on 108 pregnant women ages 18-42, at 6-32 weeks of gestation. We used a questionnaire and a 24-h recall nutrition interview. Hair samples were taken for testing and the level of each mineral was assessed using atomic absorption spectrometry...
March 14, 2018: Archives of Gynecology and Obstetrics
Meghan McGee, Shannon Bainbridge, Bénédicte Fontaine-Bisson
The fetal origins of health and disease framework has identified extremes in fetal growth and birth weight as factors associated with the lifelong generation of chronic diseases such as obesity, diabetes, cardiovascular disease, and hypertension. Maternal nutrition plays a critical role in fetal and placental development, in part by providing the methyl groups required to establish the fetus's genome structure and function, notably through DNA methylation. The goal of this narrative review is to describe the role of maternal dietary methyl donor (methionine, folate, and choline) and cofactor (zinc and vitamins B2, B6, and B12) intake in one-carbon metabolism and DNA methylation in the fetus and placenta, as well as their impacts on fetal growth and lifelong health outcomes, with specific examples in animals and humans...
February 26, 2018: Nutrition Reviews
Asanka Jayawardane, Malitha Patabendige, Dulani Samaranayake, Medini Boteju, Shamalka Dahanayake, Ruvini Perera, Sumudu Jayasinghe, Dakshila Galappatti, C N Wijeyaratne
AIM: To study case mix, risk factors, adverse outcomes and associations of hyperglycemia in pregnancy in a cohort of Sri Lankans. METHODS: Prospective observational study, from April 2011-October 2015 at a tertiary care referral center, Colombo, Sri Lanka. Data from first trimester to delivery of HIP was analyzed. Three subgroups were defined: Diabetes in pregnancy (DIP), Hyperglycemia in early Pregnancy (HIEP) [<24 weeks] and Gestational diabetes (GDM) [>24 weeks]...
March 8, 2018: Diabetes Research and Clinical Practice
Karl Krupp, Caitlyn D Placek, Meredith Wilcox, Kavitha Ravi, Vijaya Srinivas, Anjali Arun, Purnima Madhivanan
OBJECTIVE: According to the World Health Organization, about half of all pregnant women in India suffer from some form of anemia. While poor nutrition is the most common cause, social factors, such as gender and religion, also impact anemia status. This study investigates the relationship between anemia and socioeconomic and health-related factors among pregnant women in Mysore, India. DESIGN: Prospective cohort study conducted between January 2009 and 2012 SETTING: 144 rural villages ten or more kilometers outside of Mysore City received integrated antenatal care and HIV testing services provided by mobile medical clinic in their communities...
February 20, 2018: Midwifery
A Kofi Amegah, Moses Nsoh, Gifty Ashley-Amegah, Judith Anaman-Togbor
OBJECTIVE: Data on dietary vitamin D (vitD) intake, sunlight exposure, and the associated determinants are lacking in Africa. The aim of this study was to establish the factors influencing vitD intake and sunlight exposure among pregnant women in an African population with the goal of improving maternal vitD nutrition. METHODS: A population-based cross-sectional study was conducted among 703 mother-infant pairs accessing postnatal care at the five main health facilities in Cape Coast, Ghana in 2016...
November 28, 2017: Nutrition
Samuel Mersha Birru, Aysheshim Kassahun Belew, Amare Tariku
BACKGROUND: Poor nutritional status of adolescent girls has a negative effect on the next generation as undernourished adolescents enter pregnancy with poor nutrient reserve. However, there is scarcity of evidence showing the burden of stunting among adolescent girls in Ethiopia. Therefore, the objective of this study aimed to assess prevalence of stunting and associated factors among school adolescent girls in Gondar City Administration, northwest Ethiopia. METHODS: Cross-sectional study was conducted from March to April, 2017...
March 7, 2018: Italian Journal of Pediatrics
Anna Simone Frank, Angela Lupattelli, Hedvig Nordeng
INTRODUCTION: Approximately 3% to 5% of pregnant women have hypothyroidism. Despite the potential impact of untreated hypothyroidism on infant neurodevelopment, few studies have investigated the risk factors associated with discontinuation of thyroid hormone replacement therapy (THRT) in pregnancy. We aimed to identify such factors in a population of women using THRT prior to pregnancy. MATERIAL AND METHODS: Data from the Norwegian Mother and Child Cohort Study were linked to records in the Medical Birth Registry of Norway...
March 7, 2018: Acta Obstetricia et Gynecologica Scandinavica
Fernando J Roca Fraga, Malgorzata Lagisz, Shinichi Nakagawa, Nicolas Lopez-Villalobos, Hugh Blair, Paul Kenyon
Across the literature there is large variation in lamb birth weight responses to changes in the ewe pregnancy nutrition. Much of this heterogeneity has been attributed to several factors inherent to each experiment, however, the relative contribution of these experimental factors has not yet been quantified. This meta-analysis aimed to systematically review the variation in lamb birth weight responses across nutritional studies involving adult multiparous ewes. Effect sizes for individual studies were estimated using the unbiased estimator Hedges' g, whereby, positive and negative values indicate heavier and lighter treatment lambs vs...
February 28, 2018: Journal of Animal Science
Gianluca Lista, Fabio Meneghin, Ilia Bresesti, Francesca Castoldi
The development of a proper neonatal microbiota is of great importance, especially for the effects that dysbiosis has in acute and chronic diseases' onset. The microbiota, particularly the intestinal one, plays a crucial role in maintaining the health of the host, preventing colonization by pathogenic bacteria and significantly influencing the development and maturation of a normal gastrointestinal mucosal immunity. Several factors may interfere with the physiological development of microbiota, such as diseases during pregnancy, type of delivery, maternal nutrition, type of neonatal feeding, use of antibiotics, exposition to hospital environment (e...
December 22, 2017: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Juliana Araujo Teixeira, Teresa Gontijo Castro, Cameron C Grant, Clare R Wall, Ana Lúcia da Silva Castro, Rossana Pulcineli Vieira Francisco, Sandra Elisabete Vieira, Silvia Regina Dias Medici Saldiva, Dirce Maria Marchioni
BACKGROUND: Women's health during their reproductive years and whilst pregnant has implications for their children's health, both in utero and during childhood. Associations of women's pre-pregnancy dietary patterns (DP) with maternal socio-demographic characteristics and nutrient intake were investigated in ProcriAr cohort study in São Paulo/Brazil, 2012. METHODS: The DPs of 454 women were investigated by principal component factor analysis, using dietary information from a validated 110-item food frequency questionnaire...
March 1, 2018: BMC Public Health
Naomi Tamura, Tomoyuki Hanaoka, Kumiko Ito, Atsuko Araki, Chihiro Miyashita, Sachiko Ito, Hisanori Minakami, Kazutoshi Cho, Toshiaki Endo, Kazuo Sengoku, Katsuhiko Ogasawara, Reiko Kishi
From 1985 to 2013, the mean birth weight of infants in Japan decreased from 3120 g to 3000 g, and the low-birth-weight rate among live births increased from 6.3% to 9.6%. No prospective study has elucidated the risk factors for poor fetal growth and preterm birth in recent Japanese parents, such as increased parental age, maternal body figure, assisted reproductive technology (ART), and socioeconomic status. Participants were mother-infant pairs ( n = 18,059) enrolled in a prospective birth cohort in Hokkaido, Japan from 2002 to 2013...
February 21, 2018: International Journal of Environmental Research and Public Health
Malay K Mridha, Susana L Matias, Charles D Arnold, Kathryn G Dewey
Bangladesh has a high prevalence of adolescent pregnancy, but little is known about the nutritional status and dietary practices of Bangladeshi adolescents in early pregnancy or associated factors. We used the baseline data of 1552 pregnant adolescents from a longitudinal, cluster-randomized effectiveness trial conducted in northwest Bangladesh. Forty-four percent of the adolescents were short for their age, 36% had low body mass index, 28% were anemic, 10% had iron deficiency, and 32% had vitamin A deficiency...
February 18, 2018: Annals of the New York Academy of Sciences
Morgane Valentin, Perrine Coste Mazeau, Michel Zerah, Pierre François Ceccaldi, Alexandra Benachi, Dominique Luton
Neural tube defects (NTD) occur in 0.5 to 2 per 1000 pregnancies with various handicaps for the affected child. It is now well established that folic acid deficiency (absolute or relative) is a predisposing factor to this type of malformation. Several randomized controlled trials showed that high-dose folic acid (4mg) is an essential factor for prevention of neural tube defects recurrence and significantly prevents the first occurrence of neural tube defects with a lower dose (0.4mg). Other etiologies can favor the occurrence of NTD such as MTHFR polymorphism, some antiepileptic therapies, obesity and pregestational mellitus diabetes...
February 9, 2018: Annales D'endocrinologie
Aris T Papageorghiou, Stephen H Kennedy, Laurent J Salomon, Douglas G Altman, Eric O Ohuma, William Stones, Michael G Gravett, Fernando C Barros, Cesar Victora, Manorama Purwar, Yasmin Jaffer, Julia A Noble, Enrico Bertino, Ruyan Pang, Leila Cheikh Ismail, Ann Lambert, Zulfiqar A Bhutta, José Villar
The purpose of the INTERGROWTH-21st project was to develop international, prescriptive standards for fetal growth assessed by ultrasound and fundal height, preterm postnatal growth, newborn size and body composition, maternal weight gain, and infant development at the age of 2 years. Hence, we have produced, based on World Health Organization recommendations, the first comprehensive set of international standards of optimal fetal and newborn growth that perfectly match the existing World Health Organization child growth standards...
February 2018: American Journal of Obstetrics and Gynecology
Torvid Kiserud, Alexandra Benachi, Kurt Hecher, Rogelio González Perez, José Carvalho, Gilda Piaggio, Lawrence D Platt
Ultrasound biometry is an important clinical tool for the identification, monitoring, and management of fetal growth restriction and development of macrosomia. This is even truer in populations in which perinatal morbidity and mortality rates are high, which is a reason that much effort is put onto making the technique available everywhere, including low-income societies. Until recently, however, commonly used reference ranges were based on single populations largely from industrialized countries. Thus, the World Health Organization prioritized the establishment of fetal growth charts for international use...
February 2018: American Journal of Obstetrics and Gynecology
Susan M Gross, Marycatherine Augustyn, Janice L Henderson, Khrysta Baig, Christie A Williams, Bolanle Ajao, Patricia Bell-Waddy, David M Paige
OBJECTIVE: This pilot study evaluated a cost neutral, integrated Special Supplemental Nutrition Program for Women Infants and Children (WIC) and obstetrical service model designed to prevent postpartum weight retention in obese women. METHODS: A sample of women who received benefits from the Johns Hopkins (JH) WIC program and prenatal care from the JH Nutrition in Pregnancy Clinic, which provides obstetrical care for women with a BMI ≥ 30 kg/m2, participated in the WICNIP randomized clinical trial...
February 7, 2018: Maternal and Child Health Journal
Jean R Goodman, Jennifer D Peck, Alessandra Landmann, Marvin Williams, Andrew Elimian
OBJECTIVE: The objective of this study is to evaluate poor maternal nutrition, environmental exposures and vasoactive stimulants as potential risk factors for gastroschisis. METHODS: A case-control study was conducted among singleton pregnancies diagnosed in a tertiary teaching hospital in a 22-month period. Cases of gastroschisis were matched to controls at the time of diagnosis by race and maternal age. Demographics, periconceptual exposures, nutritional biomarkers, and illicit drug hair analysis were evaluated...
February 7, 2018: Journal of Maternal-fetal & Neonatal Medicine
Melanie E Gibson-Helm, Jodie Bailie, Veronica Matthews, Alison F Laycock, Jacqueline A Boyle, Ross S Bailie
INTRODUCTION: Adverse pregnancy outcomes are more common among Aboriginal and Torres Strait Islander populations than non-Indigenous populations in Australia. Later in life, most of the difference in life expectancy between Aboriginal and Torres Strait Islander women and non-Indigenous women is due to non-communicable diseases (NCDs). Most Aboriginal and Torres Strait Islander women attend health services regularly during pregnancy. Providing high-quality care within these appointments has an important role to play in improving the current and future health of women and babies...
2018: PloS One
Kathleen Lee-Sarwar, Augusto A Litonjua
Asthma most frequently develops early in life, and increased recognition of the role of lifestyle and environmental factors in asthma susceptibility raises the possibility that dietary exposures during pregnancy may influence the risk of asthma in offspring. This review discusses the latest evidence with regard to the effect of diet during pregnancy on childhood asthma risk, including potential mechanisms, outcomes of randomized clinical trials, and results from observational studies. Vitamin D and polyunsaturated fatty acid intake during pregnancy are highlighted as areas with large and growing bodies of literature to support a potential role in prenatal modulation of subsequent asthma risk...
February 2, 2018: Journal of Allergy and Clinical Immunology in Practice
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