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https://www.readbyqxmd.com/read/29045621/using-proton-pump-inhibitors-correlates-with-an-increased-risk-of-chronic-kidney-disease-a-nationwide-database-derived-case-controlled-study
#1
Shih-Chang Hung, Kuan-Fu Liao, Hung-Chang Hung, Cheng-Li Lin, Shih-Wei Lai, Po-Chang Lee, Shih-Rong Hung
Background: Those taking proton pump inhibitors (PPIs) might have a higher risk of acute kidney injury. The long-term safety, especially the PPI-associated chronic kidney disease (CKD) is the subsequent concern. Objective: This study explores the potential relationship between using PPIs and CKD in Taiwan. Methods: Using a database collated by the Taiwan National Health Insurance programme, we conducted a population-based case-controlled study to identify 16 704 cases of patients aged 20 years or older with newly diagnosed CKD between 2000 and 2013...
October 14, 2017: Family Practice
https://www.readbyqxmd.com/read/29045273/oneflorida-clinical-research-consortium-linking-a-clinical-and-translational-science-institute-with-a-community-based-distributive-medical-education-model
#2
Elizabeth Shenkman, Myra Hurt, William Hogan, Olveen Carrasquillo, Steven Smith, Andrew Brickman, David Nelson
PROBLEM: Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities- the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami-created (2010-2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings...
October 17, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29044696/relative-reductions-in-health-care-utilization-among-young-adults-before-aging-out-of-extended-dependent-coverage
#3
Weiwei Chen
The 2010 Affordable Care Act extended dependent coverage for adult children up to age 26 in the USA. Since then, considerable studies have assessed its various impacts among young adults. However, little is known about whether there is any change in health care use when young adults age out of dependent coverage. This study examines health care consumption changes among young adults prior to their aging out process. I used data from a large insurance claim database and studied health care utilization of young adults under parents' coverage during a 2-year period in a difference-in-difference framework...
October 18, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29044547/effects-of-early-dual-eligible-special-needs-plans-on-health-expenditure
#4
Yongkang Zhang, Mark L Diana
OBJECTIVE: To examine the effects of the penetration of dual-eligible special needs plans (D-SNPs) on health care spending. DATA SOURCES/STUDY SETTING: Secondary state-level panel data from Medicare-Medicaid Linked Enrollee Analytic Data Source (MMLEADS) public use file and Special Needs Plan Comprehensive Reports, Area Health Resource Files, and Medicaid Managed Care Enrollment Report between 2007 and 2011. STUDY DESIGN: A difference-in-difference strategy that adjusts for dual-eligibles' demographic and socioeconomic characteristics, state health resources, beneficiaries' health risk factors, Medicare/Medicaid enrollment, and state- and year-fixed effects...
October 18, 2017: Health Services Research
https://www.readbyqxmd.com/read/29043408/what-is-the-cost-of-free-cleft-surgery-in-the-middle-east
#5
Samar Sheriff, Hassan J Zawahrah, Lenisa V Chang, Sonay Beyatli, Haithem M Elhadi Babiker, Ashton L Roach, Natalyia Biskup, John A van Aalst
BACKGROUND: This project explores the costs of cleft lip and/or palate surgeries in Palestine and Sudan, two low- and middle-income countries (LMIC), in the Middle East. Our purpose is to examine the veracity of advertisements from international cleft organizations claiming that "250 US dollars (USD) covers the cost of a single cleft surgery." We hypothesize that the actual cost of surgery is greater than 250 USD. METHODS: Costs for each cleft surgery were organized broadly into 5 categories: hospital charges, personnel (time and money spent for health professionals to travel to LMIC, including lost wages), tests, consumables, and reusables...
October 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29042802/utilization-of-fetal-fibronectin-testing-and-pregnancy-outcomes-among-women-with-symptoms-of-preterm-labor
#6
Sean C Blackwell, Erin M Sullivan, Allison A Petrilla, Xian Shen, Kathleen A Troeger, James D Byrne
OBJECTIVES: To identify pregnant health plan members triaged through the emergency department (ED), including labor and delivery (ELD) units, with symptoms of preterm labor (PTL), and evaluate the use of fetal fibronectin (fFN) testing; and to calculate the rate of hospitalization and timing of delivery in relation to the ED visit. METHODS: Retrospective cohort study using Medical Outcomes Research for Effectiveness and Economics Registry(®), a national multipayer claims database...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29042408/impact-of-restricting-diagnostic-imaging-reimbursement-for-uncomplicated-low-back-pain-in-ontario-a-population-based-interrupted-time-series-analysis
#7
Benjamin Fine, Susan E Schultz, Lawrence White, David Henry
BACKGROUND: In 2012, the Ontario government withdrew public insurance coverage of imaging tests for uncomplicated low back pain. We studied the impact of this restriction on test ordering by physicians. METHODS: We compared the numbers of lumbar spine radiography, computed tomography (CT) and single-segment magnetic resonance imaging (MRI) studies ordered by physicians in the 3 years before and after the policy change. We linked claims data from the Ontario Health Insurance Program with physician details to calculate rates per test-ordering physician...
October 13, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29042385/association-between-malignancies-and-marfan-syndrome-a-population-based-nested-case-control-study-in-taiwan
#8
Chin-Wang Hsu, Jen-Chun Wang, Wen-I Liao, Wu-Chien Chien, Chi-Hsiang Chung, Chang-Huei Tsao, Yung-Fu Wu, Min-Tser Liao, Shih-Hung Tsai
OBJECTIVE: Marfan syndrome (MFS) involves a deficiency of the structural extracellular matrix component fibrillin-1 and overactivation of the transforming growth factor-β (TGF-β) signalling pathway. The TGF-β signalling pathway also actively participates in malignant transformation. Although anecdotal case reports have suggested associations between MFS/MFS-like conditions and several haematological and solid malignancies, such associations have not been thoroughly evaluated in large-scale studies...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29042287/the-genus-lycium-as-food-and-medicine-a-botanical-ethnobotanical-and-historical-review
#9
REVIEW
Ruyu Yao, Michael Heinrich, Caroline S Weckerle
ETHNOPHARMACOLOGICAL RELEVANCE: Lycium is widely distributed in the arid to semi-arid environments of North and South America, Africa, and Eurasia. In recent years, Lycium barbarum and L. chinense have been advertised as "superfood" with healthy properties. Despite of its popularity, there is a lack of an integrated and critical appraisal of the existing evidence for the use of Lycium. AIM OF THE STUDY: There is a need to understand: 1) Which species were used and how the uses of Lycium developed spatially and over time, 2) how uses differ among regions with different culture backgrounds, and 3) how traditional and current therapeutic and preventive health claims correlate with pharmacological findings...
October 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29041963/is-gout-a-risk-equivalent-to-diabetes-for-stroke-and-myocardial-infarction-a-retrospective-claims-database-study
#10
Jasvinder A Singh, Rekha Ramachandaran, Shaohua Yu, Shuo Yang, Fenglong Xie, Huifeng Yun, Jie Zhang, Jeffrey R Curtis
BACKGROUND: Gout is a risk factor for cardiovascular disease, but associations with specific cardiovascular outcomes, myocardial infarction (MI), and stroke are unclear. Our objective in the present study was to assess whether gout is as strong a risk factor as diabetes mellitus (DM) for incident MI and incident stroke. METHODS: In this retrospective study, we used U.S. claims data from 2007 to 2010 that included a mix of private and public health plans. Four mutually exclusive cohorts were identified: (1) DM only, (2) gout only, (3) gout and DM, and (4) neither gout nor DM...
October 17, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29041813/regulatory-science-requirements-of-labeling-of-genetically-modified-food
#11
A Alan Moghissi, Lisa M Jaeger, Dania Shafei, Lindsey L Bloom
This paper provides an overview of the evolution of food labeling in the USA. It briefly describes the three phases of agricultural development consisting of naturally occurring, cross-bred, and genetically engineered, edited or modified crops, otherwise known as Genetically Modified Organisms (GMO). It uses the Best Available Regulatory Science (BARS) and Metrics for Evaluation of Regulatory Science Claims (MERSC) to evaluate the scientific validity of claims applicable to GMO and the Best Available Public Information (BAPI) to evaluate the pronouncements by public media and others...
October 17, 2017: Critical Reviews in Biotechnology
https://www.readbyqxmd.com/read/29040592/the-association-between-igf-i-and-igfbp-3-and-incident-diabetes-in-an-older-population-of-men-and-women-in-the-cardiovascular-health-study
#12
Chino S Aneke-Nash, Xiaonan Xue, Qibin Qi, Mary L Biggs, Anne Cappola, Lewis Kuller, Michael Pollak, Bruce M Psaty, David Siscovick, Kenneth Mukamal, Howard D Strickler, Robert C Kaplan
Context: Insulin like growth factor-I (IGF-I) has structural/functional similarities with insulin and may play a role in glucose homeostasis, along with IGF binding protein-3 (IGFBP-3), which binds the majority of circulating IGF-I. Objective: To assess whether IGF-I and IGFBP-3 are associated with higher risk of incident diabetes in older adults. Design: Participants in the Cardiovascular Health Study (n=3133), a cohort of adults aged ≥65 years, were observed for 16 years (n=3133) for the development of incident diabetes...
October 12, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29040495/applying-sequence-clustering-techniques-to-explore-practice-based-ambulatory-care-pathways-in-insurance-claims-data
#13
Verena Vogt, Stefan M Scholz, Leonie Sundmacher
Background: Care pathways are a widely used mean to ensure well-coordinated and high quality care by defining the optimal timing and interval of health services for a specific indication. However, evidence on common sequences of services actually followed by patients has rarely been quantified. This study aims to explore whether sequence clustering techniques can be used to empirically identify typical treatment sequences in ambulatory care for heart failure (HF) patients and compare their effectiveness...
October 12, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29039055/treatment-patterns-complications-and-health-care-utilization-among-endometriosis-patients-undergoing-a-laparoscopy-or-a-hysterectomy-a-retrospective-claims-analysis
#14
Eric S Surrey, Ahmed M Soliman, Hongbo Yang, Ella Xiaoyan Du, Bowdoin Su
INTRODUCTION: Hysterectomy and laparoscopy are common surgical procedures used for the treatment of endometriosis. This study compares outcomes for women who received either procedure within the first year post initial surgery. METHODS: The study used data from the Truven Health MarketScan claims databases from 2004 to 2013 to identify women aged 18-49 years who received an endometriosis-related laparoscopy or hysterectomy. Patients were excluded if they did not have continuous insurance coverage from 1 year before through 1 year after their endometriosis-related procedure, if they were diagnosed with uterine fibroids prior to or on the date of surgery (i...
October 16, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29037057/-one-year-adherence-of-ramipril-versus-ramipril-amlodipine-fixed-dose-combination-therapy-in-hypertension
#15
Gábor Simonyi, Tamás Ferenci
INTRODUCTION: In the treatment of hypertension avoiding adverse cardiovascular complications to achieve target blood pressure is essential. The appropriate drug selection, and if necessary to change to combination therapy, patients adherence is important which may help fixed dose combination. AIM: The aim of the authors was to investigate the one year adherence of the ramipril and ramipril/amlodipine fixed dose combination in hypertensive patients. METHOD: Prescriptions database of the National Health Insurance Fund in Hungary on pharmacy-claims was analysed between October 1, 2012 and September 30, 2013...
October 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29036011/evaluating-the-impact-of-prescription-fill-rates-on-risk-stratification-model-performance
#16
Hsien-Yen Chang, Thomas M Richards, Kenneth M Shermock, Stacy Elder Dalpoas, Hong J Kan, G Caleb Alexander, Jonathan P Weiner, Hadi Kharrazi
BACKGROUND: Risk adjustment models are traditionally derived from administrative claims. Prescription fill rates-extracted by comparing electronic health record prescriptions and pharmacy claims fills-represent a novel measure of medication adherence and may improve the performance of risk adjustment models. OBJECTIVE: We evaluated the impact of prescription fill rates on claims-based risk adjustment models in predicting both concurrent and prospective costs and utilization...
October 13, 2017: Medical Care
https://www.readbyqxmd.com/read/29035430/the-use-pattern-and-clinical-impact-of-new-antiplatelet-agents-including-prasugrel-and-ticagrelor-on-30-day-outcomes-after-acute-myocardial-infarction-in-korea-korean-health-insurance-review-and-assessment-data
#17
Choongki Kim, Dong Ho Shin, Chul Min Ahn, Jung Sun Kim, Byeong Keuk Kim, Young Guk Ko, Donghoon Choi, Myeong Ki Hong, Juhee Park, Hyeyeong Lee, Yoon Jung Choi, Youn Song Choi, Sang Kwon Oh, Yangsoo Jang
BACKGROUND AND OBJECTIVES: Despite the favorable efficacy of new antiplatelet agents demonstrated in randomized controlled trials, their clinical implications in Korea are unclear. The purpose of this study was to investigate trends in antiplatelet agent use for acute myocardial infarction (AMI) and their impact on 30-day clinical outcomes. METHODS: AMI patients undergoing percutaneous coronary intervention between 2010 and 2015 were assessed using claim data from the Health Insurance Review and Assessment Service...
September 12, 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/29035094/doktor-kot-doktor-sla%C3%A2-%C3%A2-book-doctors-plant-doctors-and-the-segmentation-of-the-medical-market-place-in-meghalaya-northeast-india
#18
Sandra Albert, John Porter, Judith Green
Despite decades of research on India's plural health care market, the practices of many local health traditions outside the allopathic and codified traditions are under-studied. Drawing on interview and observational data, this paper explores the space in which indigenous traditional Khasi healers in Meghalaya state, northeast India, practice. Khasi indigenous healers describe themselves as doktor sla, plant doctors, to distinguish themselves from doktor kot, or book doctors. This distinction operates as a rhetorical resource, utilised to carve a distinct sphere of expertise in relation to the allopathic sector, and to mark claims for the specifically local appropriateness of traditional practices within a shifting market of state-sponsored provision...
October 16, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/29034792/medical-resource-utilization-and-costs-for-total-hip-arthroplasty-benchmarking-an-anterior-approach-technique-in-the-medicare-population
#19
Atul F Kamath, Abhishek S Chitnis, Chantal Holy, Jason Lerner, Brian Curtin, Steve Lochow, Charles DeCook, Joel M Matta
AIMS: The anterior approach (AA) for total hip arthroplasty (THA) is associated with more rapid recovery when compared to traditional approaches. The purpose of this study was to benchmark healthcare resource utilization and costs for patients with THA via AA relative to matched patients. MATERIALS AND METHODS: We queried Medicare claims data (2012-2014) to identify patients who received THA via an AA from experienced surgeons, and matched these patients to a control cohort (all THA approaches)...
October 15, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29034379/medical-malpractice-an-introduction-for-the-dental-practitioner
#20
Inbal Blau, Liran Levin
With the plethora of medical malpractice claims, health care providers are forced to deal not only with medical matters but also with legal issues. Thus, unfortunately, every time health care providers give a medical treatment, they should be aware of the legal implications of their act. Most medical malpractice cases will be resolved in civil law and will have financial implications, but in extreme cases (such as causing death by negligence) criminal procedure may also be conducted, meaning criminal sanctions (imprisonment or fine)...
2017: Quintessence International
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