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https://www.readbyqxmd.com/read/28943454/coronary-artery-calcium-quantification-on-first-second-and-third-generation-dual-source-ct-a-comparison-study
#1
Marleen Vonder, Gert Jan Pelgrim, Sèvrin E M Huijsse, Holger Haubenreisser, Mathias Meyer, Peter M A van Ooijen, Matthijs Oudkerk, Thomas Henzler, Rozemarijn Vliegenthart
BACKGROUND: Differences in coronary artery calcium (CAC) quantification of successive CT systems of one vendor could impact results of CAC screening and progression studies. The purpose of this study is to compare CAC quantification between three generations of dual-source computed tomography (DSCT) systems. METHODS: Three DSCT generations were used to repeatedly scan an anthropomorphic chest phantom and three inserts. The first and second insert contained 100 small and nine large calcifications, respectively, to determine detectability, and the Agatston and (calibrated) mass score, respectively...
September 8, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28937491/improved-calcium-scoring-at-dual-energy-computed-tomography-angiography-using-a-high-z-contrast-element-and-novel-material-separation-technique
#2
Jack W Lambert, Yuxin Sun, Karen G Ordovas, Robert G Gould, Sizhe Wang, Benjamin M Yeh
OBJECTIVES: The aim of this study was to compare the accuracy of existing dual-energy computed tomography (CT) angiography coronary artery calcium scoring methods to those obtained using an experimental tungsten-based contrast material and a recently described contrast material extraction process (CMEP). METHODS: Phantom coronary arteries of varied diameters, with different densities and arcs of simulated calcified plaque, were sequentially filled with water, iodine, and tungsten contrast materials and scanned within a thorax phantom at rapid-kVp-switching dual-energy CT...
September 20, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28931782/tumor-necrosis-factor-%C3%AE-gene-expression-in-epicardial-adipose-tissue-is-related-to-coronary-atherosclerosis-assessed-by-computed-tomography
#3
Toshiro Kitagawa, Hideya Yamamoto, Takuya Hattori, Kazuhiro Sentani, Shinya Takahashi, Atsuhiro Senoo, Yumiko Kubo, Wataru Yasui, Taijiro Sueda, Yasuki Kihara
AIMS: Tumor necrosis factor (TNF)-α reportedly has key pro-inflammatory properties in both atherosclerosis and adipocytes. To further investigate the biologic impact of epicardial adipose tissue (EAT) on coronary atherosclerosis, we evaluated the relationship between TNF-α gene expression in EAT and clinically-assessed coronary atherosclerosis on computed tomography (CT). METHODS: We studied 47 patients before cardiac surgery (coronary artery bypass grafting [CABG], n=26; non-CABG, n=21), assessing visceral adipose tissue (VAT) area, EAT volume, coronary calcium score (CCS), and the presence of non- and/or partially-calcified coronary plaque (NCP) on CT angiography...
September 20, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28917674/prognostic-value-of-risk-factors-calcium%C3%A2-score-coronary-cta-myocardial%C3%A2-perfusion-imaging-and-invasive%C3%A2-coronary-angiography-in-kidney%C3%A2-transplantation-candidates
#4
Simon Winther, My Svensson, Hanne Skou Jørgensen, Laust Dupont Rasmussen, Niels Ramsing Holm, Lars Christian Gormsen, Kirsten Bouchelouche, Hans Erik Bøtker, Per Ivarsen, Morten Bøttcher
OBJECTIVES: This study sought to perform a prospective head-to-head comparison of the predictive value of clinical risk factors and a variety of cardiac imaging modalities including coronary artery calcium score (CACS), coronary computed tomography angiography (CTA), single-photon emission computed tomography (SPECT), and invasive coronary angiography (ICA) on major adverse cardiac events (MACE) and all-cause mortality in kidney transplantation candidates. BACKGROUND: Current guidelines recommend screening for coronary artery disease in kidney transplantation candidates...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28916241/relationship-of-echocardiographic-epicardial-fat-thickness-and-epicardial-fat-volume-by-computed-tomography-with-coronary-artery-calcification-data-from-the-caesar-study
#5
Byung Jin Kim, Jung Gyu Kang, Sung Ho Lee, Jong Young Lee, Ki Chul Sung, Bum Soo Kim, Jin Ho Kang
BACKGROUND AND AIMS: No study has assessed the association between echocardiographic epicardial fat thickness (EFT) and computed tomography (CT)-based epicardial fat volume (EFV) and coronary artery calcification. The aim of this study is to evaluate the association between EFT and EFV and coronary artery calcification. METHODS: Among the 2,299 individuals enrolled in the CArdiometabolic risk, Epicardial fat, and Subclinical Atherosclerosis Registry (CAESAR) study, 2,276 (1,851 men; mean age 45 ± 8...
September 12, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/28901232/decellularized-allografts-for-right-ventricular-outflow-tract-reconstruction-in-children
#6
Francisco Diniz Affonso da Costa, Jonathan R G Etnel, Renato Torres, Eduardo M Balbi Filho, Rafael Torres, Allyson Calixto, Leonardo A Mulinari
OBJECTIVE: Determine the midterm outcomes of decellularized allografts for right ventricular outflow tract (RVOT) reconstruction in children less than 12 years of age. METHODS: The study included all consecutive patients submitted to RVOT reconstruction with decellularized allografts between June 2006 and June 2016. Besides clinical and echocardiographic control, 20 patients with more than five years of follow-up were evaluated with computed tomography (CT) scans to determine allograft diameters and calcium scores...
September 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28895189/-diagnosis-of-a-hiatal-hernia-from-a-ct-coronary-artery-calcium-scan
#7
Edmund Kenneth Kerut, John T Balart
Identification of a hiatal hernia by computed tomography (CT) scanning, and particularly with axial imaging from a coronary artery calcium score exam, is often subjective. There are several CT features that are diagnostic or at least suggestive of a hiatal hernia. As a hiatal hernia may be the etiology of a chest pain syndrome, it is important to be aware of CT findings suggestive of such.
September 12, 2017: Echocardiography
https://www.readbyqxmd.com/read/28886899/frailty-and-subclinical-coronary-atherosclerosis-the-multicenter-aids-cohort-study-macs
#8
Sai Krishna C Korada, Di Zhao, Martin Tibuakuu, Todd T Brown, Lisa P Jacobson, Eliseo Guallar, Robert K Bolan, Frank J Palella, Joseph B Margolick, Jeremy J Martinson, Matthew J Budoff, Wendy S Post, Erin D Michos
BACKGROUND AND AIMS: Frailty and cardiovascular disease share many risk factors. We evaluated whether frailty is independently associated with subclinical coronary atherosclerosis and whether any relationships differ by HIV-serostatus. METHODS: We studied 976 [62% HIV-infected] male participants of the Multicenter AIDS Cohort Study who underwent assessment of frailty and non-contrast cardiac CT scanning; of these, 747 men also underwent coronary CT angiography (CCTA)...
August 26, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28865096/the-predictive-value-of-coronary-artery-calcium-detected-by-computed-tomography-in-a-prospective-study-on-cardiac-allograft-vasculopathy-in-heart-transplant-patients
#9
Anne Günther, Rune Andersen, Einar Gude, Jarl Jakobsen, Thor Edvardsen, Leiv Sandvik, Andreas Abildgaard, Lars Aaberge, Lars Gullestad
The predictive value of coronary artery calcium (CAC) in heart transplant (HTX) patients is not established. We explored if the absence of CAC on computed tomography (CT) could exclude moderate and severe cardiac allograft vasculopathy (CAV₂₋₃; the International Society for Heart and Lung Transplantation [ISHLT] recommended nomenclature) and significant coronary artery stenosis (diameter reduction ≥50%), and predict long-term clinical outcomes. HTX recipients (n=133) were prospectively included and underwent CT for CAC scoring and invasive coronary angiography (ICA) 7...
September 2, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28865035/effect-of-zoledronic-acid-on-lumbar-spinal-fusion-in-osteoporotic-patients
#10
Qirui Ding, Jian Chen, Jin Fan, Qingqing Li, Guoyong Yin, Lipeng Yu
PURPOSE: To investigate the effect of zoledronic acid (ZA) on lumbar spinal fusion in patients with osteoporosis. METHODS: This retrospective study includes 94 osteoporotic patients suffering from lumbar degenerative diseases or lumbar fracture who underwent lumbar spinal fusion in our institution from January 2013 to August 2014. They were divided into ZA group and control group according to whether the patient received ZA infusion or not. The patients in ZA group were given 5 mg intravenous ZA at the 3rd-5th days after operation...
September 1, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28860893/calcification-remodeling-index-characterized-by-cardiac-ct-as-a-novel-parameter-to-predict-the-use-of-rotational-atherectomy-for-coronary-intervention-of-lesions-with-moderate-to-severe-calcification
#11
Mengmeng Yu, Yuehua Li, Wenbin Li, Zhigang Lu, Meng Wei, Jiayin Zhang
OBJECTIVE: To assess the feasibility of calcification characterization by coronary computed tomography angiography (CCTA) to predict the use of rotational atherectomy (RA) for coronary intervention of lesions with moderate to severe calcification. MATERIALS AND METHODS: Patients with calcified lesions treated by percutaneous coronary intervention (PCI) who underwent both CCTA and invasive coronary angiography were retrospectively included in this study. Calcification remodeling index was calculated as the ratio of the smallest vessel cross-sectional area of the lesion to the proximal reference luminal area...
September 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28833626/cardiac-imaging-to-detect-coronary-artery-disease-in-athletes-aged-35-years-and-older-a-scoping-review
#12
Thijs L Braber, Johannes B Reitsma, Arend Mosterd, Martin J Willemink, Niek H J Prakken, Martin Halle, Sanjay Sharma, Birgitta K Velthuis
Sudden cardiac death (SCD) is a devastating event in athletes. Screening efforts that were first directed at athletes younger than 35 years, are now focusing on the rapidly growing group of older sportspersons. Athletes aged ≥35 years have a 10-fold increased risk of exercise-related cardiac arrest, mostly due to coronary artery disease (CAD). Although cardiac imaging is pivotal in identifying CAD, the role of imaging modalities in screening asymptomatic older sportspersons remains unclear. We performed a scoping review to identify the role of cardiac imaging to detect CAD in older sportspersons and to identify gaps in the existing literature...
August 23, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28832417/2016-scct-str-guidelines-for-coronary-artery-calcium-scoring-of-noncontrast-noncardiac-chest-ct-scans-a-report-of-the-society-of-cardiovascular-computed-tomography-and-society-of-thoracic-radiology
#13
Harvey S Hecht, Paul Cronin, Michael J Blaha, Matthew J Budoff, Ella A Kazerooni, Jagat Narula, David Yankelevitz, Suhny Abbara
The Society of Cardiovascular Computed Tomography (SCCT) and the Society of Thoracic Radiology (STR) have jointly produced this document. Experts in this subject have been selected from both organizations to examine subject-specific data and write this guideline in partnership. A formal literature review, weighing the strength of evidence has been performed. When available, information from studies on cost was considered. Computed tomography (CT) acquisition, CAC scoring methodologies and clinical outcomes are the primary basis for the recommendations in this guideline...
September 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28797406/ct-detected-growth-of-coronary-artery%C3%A2-calcification-in-asymptomatic-middle-aged-subjects-and-association-with-15-biomarkers
#14
Søren Zöga Diederichsen, Mette Hjortdal Grønhøj, Hans Mickley, Oke Gerke, Flemming Hald Steffensen, Jess Lambrechtsen, Niels Peter Rønnow Sand, Lars Melholt Rasmussen, Michael Hecht Olsen, Axel Diederichsen
OBJECTIVES: This study sought to determine the incidence and progression of coronary artery calcification (CAC) in asymptomatic middle-aged subjects and to evaluate the value of a broad panel of biomarkers in the prediction of CAC growth. BACKGROUND: CAC continues to be a major risk factor, but the value of biochemical markers in predicting CAC incidence and progression remains unresolved. METHODS: At baseline, 1,227 men and women underwent traditional risk assessment and a computed tomography (CT) scan to determine the CAC score...
August 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28791822/a-coronary-proatherosclerotic-marker-pregnancy-associated-plasma-protein-a-and-its-association-with-coronary-calcium-score-and-carotid-intima-media-thickness
#15
Abdullah Guven, Bora Demircelik, Ozgul Malcok Gurel, Okan Er, Halil Ibrahim Aydin, Alper Bozkurt
BACKGROUND: Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for the greatest number of deaths in westernized societies, with numbers increasing at a marked rate in developing countries. Coronary calcium score (CCS), carotid intima-media thickness (CIMT) and pregnancy-associated plasma protein A (PAPP-A) are predictors for the development of atherosclerosis. OBJECTIVES: This study was aimed to investigate the relationship between CCS, CIMT and PAPP-A for earlier diagnosis of atherosclerosis...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28756086/iterative-beam-hardening-correction-with-advanced-modeled-iterative-reconstruction-in-low-voltage-ct-coronary-calcium-scoring-with-tin-filtration-impact-on-coronary-artery-calcium-quantification-and-image-quality
#16
Christian Tesche, Carlo N De Cecco, U Joseph Schoepf, Taylor M Duguay, Moritz H Albrecht, Damiano Caruso, Akos Varga-Szemes, Virginia W Lesslie, Ullrich Ebersberger, Christian Canstein, Christian Thilo, Ellen Hoffmann, Thomas Allmendinger, John W Nance
OBJECTIVE: We investigated the impact of iterative beam-hardening correction (IBHC) with advanced modeled iterative reconstruction (ADMIRE) of ultra-low radiation-dose tin filtered (Sn100 kVp) CACS acquisitions on image quality, calcium quantification, and risk classification. METHODS: CT data of 60 patients (55% male, age 62.3 ± 9.8years) who underwent a 3rd generation dual-source CACS scan using a prospectively ECG-triggered 100 kVp sequential acquisition protocol with tin filtration (Sn100 kVp) were reconstructed using IBHC with filtered back projection (FBP) and ADMIRE with strength levels of three and five...
July 24, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28754439/myocardial-blood-flow-reserve-is-impaired-in-patients-with-aortic-valve-calcification-and-unobstructed-epicardial-coronary-arteries
#17
Karen Nel, Michael C Y Nam, Chris Anstey, Christopher J Boos, Edward Carlton, Roxy Senior, Juan Carlos Kaski, Ahmed Khattab, Delva Shamley, Christopher D Byrne, Tony Stanton, Kim Greaves
BACKGROUND: Although calcific aortic valve disease (CAVD) is associated with coronary atherosclerosis, it is not known whether early CAVD is associated with coronary microcirculatory dysfunction (CMD). We sought to investigate the relationship between myocardial blood flow reserve (MBFR) - a measure of CMD, and early CAVD in the absence of obstructive epicardial coronary artery disease. We also determined whether this relationship was independent of coronary artery disease (CAD) and hs-CRP, a marker of systemic inflammation...
December 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28754436/sex-differences-in-coronary-atherosclerosis-progression-and-major-adverse-cardiac-events-in-patients-with-suspected-coronary-artery-disease
#18
Hui Gu, Yang Gao, Haiping Wang, Zhihui Hou, Lei Han, Ximing Wang, Bin Lu
BACKGROUND: Little is known about the influence of coronary atherosclerosis progression on the risk of major adverse cardiac events (MACE). Similarly, differences between men and women regarding atherosclerosis progression are poorly understood. The purpose of this study was to investigate the progression of coronary atherosclerosis by coronary CT angiography (coronary CTA) in men and women, and to evaluate its prognostic value regarding MACE. METHODS: This study included 1046 patients with suspected coronary artery disease (CAD) who underwent serial coronary CTA because of new or worsening symptoms or because follow-up coronary CTA had been recommended by attending physicians...
July 16, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28741065/coronary-calcium-scoring-of-ct-attenuation-correction-scans-automatic-manual-or-visual
#19
EDITORIAL
Shifali Dumeer, Andrew J Einstein
No abstract text is available yet for this article.
July 24, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28740456/carotid-artery-stiffness-digital-endothelial-function-and-coronary-calcium-in-patients-with-essential-thrombocytosis-free-of-overt-atherosclerotic-disease
#20
Matjaz Vrtovec, Ajda Anzic, Irena Preloznik Zupan, Katja Zaletel, Ales Blinc
BACKGROUND: Patients with myeloproliferative neoplasms (MPNs) are at increased risk for atherothrombotic events. Our aim was to determine if patients with essential thrombocytosis (ET), a subtype of MPNs, free of symptomatic atherosclerosis, have greater carotid artery stiffness, worse endothelial function, greater coronary calcium and carotid plaque burden than control subjects. PATIENTS AND METHODS: 40 ET patients without overt vascular disease, and 42 apparently healthy, age and sex-matched control subjects with comparable classical risk factors for atherosclerosis and Framingham risk of coronary disease were enrolled...
June 2017: Radiology and Oncology
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