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https://www.readbyqxmd.com/read/29118296/mismatch-between-fetal-sexing-and-birth-phenotype-a%C3%A2-case-of-complete-androgen-insensitivity-syndrome
#1
Keisuke Yoshii, Yasuhiro Naiki, Yumiko Terada, Maki Fukami, Reiko Horikawa
With advancing maternal age, the number of prenatal genetic tests is increasing in many countries. Prenatal genetic tests, such as amniocentesis, chorionic villus sampling and non-invasive prenatal testing, can disclose fetal chromosomal sex, although these tests were originally designed to prenatally diagnose chromosomal aneuploidies, such as trisomy 21, 18 and 13. Complete androgen insensitivity syndrome (CAIS) is an X-linked recessive disorder caused by an androgen receptor dysfunction leading to hormone resistance...
November 9, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28876577/surgical-burden-of-disease-at-a-regional-hospital-in-south-africa
#2
O Swart, J Pape, R Duvenage
BACKGROUND: There is limited published data describing the nature of surgical admissions at a regional level in the South African context. Worcester Hospital General Surgery has introduced an electronic online database to manage its surgical services. This study uses that database to evaluate the surgical burden of disease for the Cape Winelands East and Overberg districts of the Western Cape. METHOD: Admissions data were prospectively captured from February 2012 to January 2016, then retrospectively reviewed and classified into 5 types: (1) elective surgery/investigations (ESI); (2) trauma; (3) burns; (4) non-traumatic surgical emergencies (NTSE); (5) unplanned readmission within 30 days...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/27941567/a-serous-peritoneal-cancer-revealing-itself-with-double-breast-cancer-metastases-in-2-different-periods
#3
Kemal Beksac, Cigdem Irkkan, Guldeniz Argun, Bahadir Cetin
A 72-year-old woman presented with a mass on the right axilla. This was thought to be an occult breast cancer case, and the patient was treated with modified radical mastectomy, followed by hormonotherapy. Two years later she presented with incarcerated umbilical hernia. Pathology revealed Sister Mary Joseph's nodule inside the hernia sac. Further evaluation revealed that the primary tumor was papillary serous carcinoma of the peritoneal surface. The patient received adjuvant chemotherapy. Two years later the metastatic tumor was located on the other breast...
December 9, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27257696/the-american-association-for-the-surgery-of-trauma-grading-scale-for-16-emergency-general-surgery-conditions-disease-specific-criteria-characterizing-anatomic-severity-grading
#4
Gail T Tominaga, Kristan L Staudenmayer, Shahid Shafi, Kevin M Schuster, Stephanie A Savage, Steven Ross, Peter Muskat, Nathan T Mowery, Preston Miller, Kenji Inaba, Mitchell Jay Cohen, David Ciesla, Carlos V R Brown, Suresh Agarwal, Michel B Aboutanos, Garth H Utter, Marie Crandall
No abstract text is available yet for this article.
September 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/26660690/drugs-system-improving-the-effects-of-clinical-pathways-a-systematic-study
#5
Shan Wang, Xiaohe Zhu, Xian Zhao, Yang Lu, Zhifu Yang, Xiaoliang Qian, Weiwei Li, Lixiazi Ma, Huning Guo, Jingwen Wang, Aidong Wen
The aim of the study is to assess the feasibility of Drugs Rational Usage Guideline System (DRUGS)-supported clinical pathway (CP) for breast carcinoma, cataract, inguinal hernia and 2-diabetes mellitus whether the application of such a system could improve work efficiency, medical safety, and decrease hospital cost. Four kinds of diseases which included 1773 cases (where 901 cases using paper-based clinical pathways and 872 cases using DRUGS-supported clinical pathways) were selected and their demographic and clinical data were collected...
March 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/26524959/baseline-cerebral-oximetry-values-depend-on-non-modifiable-patient-characteristics
#6
Lucía Valencia, Aurelio Rodríguez-Pérez, Nazario Ojeda, Romen Yone Santana, Laura Morales, Oto Padrón
OBJECTIVE: The aim of the present study was to evaluate baseline regional cerebral oxygen saturation (rSO2) values and identify factors influencing preoperative rSO2 in elective minor surgery. STUDY DESIGN: Observational analysis post-hoc. PATIENTS AND METHODS: Observational post-hoc analysis of data for the patient sample (n=50) of a previously conducted clinical trial in patients undergoing tumourectomy for breast cancer or inguinal hernia repair...
December 2015: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/26313111/epidemiology-of-untreated-non-obstetric-surgical-disease-in-burera-district-rwanda-a-cross-sectional-survey
#7
Allison F Linden, Rebecca Maine, Bethany L Hedt-Gauthier, Emmanual Kamanzi, Gita Mody, Georges Ntakiyiruta, Grace Kansayisa, Edmond Ntaganda, Francine Niyonkuru, Joel Mubiligi, Tharcisse Mpunga, John G Meara, Robert Riviello
BACKGROUND: In low-income and middle-income countries, surgical epidemiology is largely undefined at the population level, with operative logs and hospital records serving as a proxy. This study assesses the distribution of surgical conditions that contribute the largest burden of surgical disease in Burera District, in northern Rwanda. We hypothesise that our results would yield higher rates of surgical disease than current estimates (from 2006) for similar low-income countries, which are 295 per 100 000 people...
April 27, 2015: Lancet
https://www.readbyqxmd.com/read/26313110/validation-of-a-community-based-survey-assessing-non-obstetric-surgical-conditions-in-burera-district-rwanda
#8
Allison F Linden, Rebecca Maine, Bethany L Hedt-Gauthier, Emmanual Kamanzi, Gita Mody, Georges Ntakiyiruta, Grace Kansayisa, Edmond Ntaganda, Francine Niyonkuru, Joel Mubiligi, Tharcisse Mpunga, John G Meara, Robert Riviello
BACKGROUND: Community-based surveillance methods to monitor epidemiological progress in surgery have not yet been employed for surgical capacity building. The aim of this study was to create and assess the validity of a questionnaire that collected data for untreated surgically correctable diseases throughout Burera District, northern Rwanda, to accurately plan for surgical services. METHODS: A structured interview to assess for the presence or absence of ten index surgically treatable conditions (breast mass, cleft lip/palate, club foot, hernia or hydrocele [adult and paediatric]), hydrocephalus, hypospadias, injuries or wounds, neck mass, undescended testes, and vaginal fistula) was created...
April 27, 2015: Lancet
https://www.readbyqxmd.com/read/26313099/surgical-need-in-an-ageing-population-a-cluster-based-household-survey-in-nepal
#9
Barclay T Stewart, Even Wong, Shailvi Gupta, Santosh Bastola, Sunil Shrestha, Adam L Kushner, Benedict C Nwomeh
BACKGROUND: With an ageing global population comes major non-communicable disease burden, especially in low-income and middle-income countries. An unknown proportion of this burden is treatable or palliated with surgery. This study aimed to estimate the surgical needs of individuals aged 50 years or older in Nepal. METHODS: A two-stage, 30 randomised cluster by 30 households, community-based survey was performed in Nepal with the validated Surgeons OverSeas Assessment of Surgical Need (SOSAS)...
April 27, 2015: Lancet
https://www.readbyqxmd.com/read/26170756/most-cited-articles-in-general-surgery-from-turkey
#10
Burhan Mayir, Tuna Bilecik, Uğur Doğan, Ümit Koç, Cemal Özben Ensari, Mehmet Tahir Oruç
OBJECTIVE: The citation number of an article gives us information about its quality and contribution to science. In this article, we aimed to find the most frequently cited article in general surgery from Turkey, and evaluate how these articles in general surgery contributed to the world literature. MATERIAL AND METHODS: We used the science citation index expanded database to find the most frequently cited articles in general surgery from Turkey. RESULTS: Among the 52 articles found, the most common subjects were as follows: hydatid cyst (21...
2015: Ulusal Cerrahi Dergisi
https://www.readbyqxmd.com/read/26072926/congenital-generalized-lipodystrophy-identification-of-novel-variants-and-expansion-of-clinical-spectrum
#11
A Haghighi, Z Kavehmanesh, A Haghighi, F Salehzadeh, F Santos-Simarro, L Van Maldergem, L Cimbalistiene, F Collins, M Chopra, S Al-Sinani, S Dastmalchian, D C de Silva, H Bakhti, A Garg, P Hilbert
Congenital generalized lipodystrophy (CGL) is an autosomal recessive disorder with two major subtypes. Variants in AGPAT2 result in CGL type 1 with milder manifestations, whereas BSCL2 variants cause CGL type 2 with more severe features. Muscle hypertrophy caused by lack of adipose tissue is present early in life in CGL patients. Our aim was to investigate 10 CGL patients from 7 different countries and report genotype-phenotype relationships. Genetic analysis identified disease-causing variants in AGPAT2 (five patients) and in BSCL2 (five patients), including three novel variants; c...
June 15, 2015: Clinical Genetics
https://www.readbyqxmd.com/read/26019238/the-weekend-effect-in-plastic-surgery-analyzing-weekday-versus-weekend-admissions-in-body-contouring-procedures-from-2000-to-2010
#12
COMPARATIVE STUDY
Kashyap Komarraju Tadisina, Karan Chopra, Devinder P Singh
BACKGROUND: Body contouring operations are a quickly becoming the most commonly performed operations by American plastic surgeons, mirroring the increase in bariatric surgery in the US over the last decade. Despite previous studies showing worse patient outcomes on weekend admissions for non-emergent cases (spine, breast, and hernia), there is no comparative data reported regarding body contouring procedures. OBJECTIVE: The authors aimed to determine whether body contouring surgery results in worse outcomes when performed on weekends versus weekdays...
November 2015: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/25818034/perioperative-care-of-elderly-outpatients-a-review
#13
REVIEW
Carlo Grifasi, Armando Calogero, Anna Esposito, Concetta Dodaro
INTRODUCTION: Epidemiological data show a continuous expansion of elderly population in Europe. Older individuals require more medical services relative to their younger counterparts. The aim of this review was to summarize the most recent considerations in regards to preoperative assessment, postoperative outcomes, patient satisfaction and cost-effectiveness analysis of day surgery in the elderly. METHODS: This review considered studies that included older patients who were undergoing day surgery general procedures (such as inguinal hernia repair, excision of breast lump, haemorrhoidectomy)...
March 2015: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/25703139/tamoxifen-induces-the-development-of-hernia-in-mice-by-activating-mmp-2-and-mmp-13-expression
#14
Xingzhe Ma, Ying Liu, Qixue Wang, Yuanli Chen, Mengyang Liu, Xiaoju Li, Rong Xiang, Yuquan Wei, Yajun Duan, Jihong Han
Hernia is a disease with defects in collagen synthesis/metabolism. However, the underlying mechanisms for hernia formation have not been fully defined. Tamoxifen is a selective estrogen receptor modulator and used for patients with breast cancer. Tamoxifen also has pleiotropic and side effects. Herein, we report that tamoxifen treatment resulted in an appearance of a large bulge in the low abdomen between the hind legs in male but not in female mice. The autopsy demonstrated that the low abdominal wall was broken and a large amount of intestine herniated out of the abdominal cavity...
May 2015: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/25195634/perioperative-care-of-elderly-outpatient-a-review
#15
Carlo Grifasi, Armando Calogero, Anna Esposito, Concetta Dodaro
INTRODUCTION: Epidemiological data show a continuous expansion of elderly population in Europe. Older individuals require more medical services relative to their younger counterparts. The aim of this review was to summarize the most recent considerations in regards to preoperative assessment, postoperative outcomes, patient satisfaction and cost-effectiveness analysis of day surgery in the elderly. METHODS: This review considered studies that included older patients who were undergoing day surgery general procedures (such as inguinal hernia repair, excision of breast lump, haemorrhoidectomy)...
2014: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/25154885/the-use-of-unilateral-or-bilateral-external-oblique-myocutaneous-flap-in-the-reconstruction-of-lower-abdominal-wall-or-groin-defects-after-malignant-tumor-resection
#16
Ruming Zhang, Chunmeng Wang, Yong Chen, Biqiang Zheng, Yingqiang Shi
BACKGROUND: External oblique myocutaneous flap (EOMF) has been used successfully for many years in reconstructive plastic surgery, its function is mainly concentrated in the restoration of chest wall defects following breast cancer resection. However, for the lower abdominal wall or groin defects after malignant tumor resection, reconstruction with EOMF is little reported. In this study, we report our experience with EOMF downward transposition to repair the defects. METHODS: 12 patients with malignant diseases in the lower abdominal wall or groin underwent aggressive tumor resection, the defects were reconstructed immediately with EOMF...
December 2014: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/24896767/metastases-to-hernial-sac-detected-on-18-f-fdg-pet-ct
#17
Sachin Jain, Sellam Karunanithi, Punit Sharma, Suhas Singla, Rakesh Kumar
The presence of primary or metastatic cancer within a hernial sac is uncommon. Based on the anatomical relation of the tumor to the sac, malignant tumors within hernia sac are classified into 3 groups; intrasaccular, saccular, and extrasaccular. We present F-FDG PET/CT images of 2 cases of hernia sac metastasis, one from non-small cell lung cancer and another from infiltrating ductal breast carcinoma. F-FDG PET/CT was useful in these cases for detection of the metastatic lesion within hernial sac and thus in assessment of total disease burden...
July 2014: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/24857417/diagnostic-value-of-automated-3d-ultrasound-for-incisional-hernia
#18
Liang Fang, Lin Chen, Wen-Ping Wang, Yue Chen, Yun Pang, Zhi-Ying Qiu, Jian-Xiong Tang
The automated volume scanning system (AVSS) has been applied in breast diseases, but its use in incisional hernias has not been reported. In this study, conventional handheld B-mode ultrasound (HHUS) and AVSS examined a total of 122 hernia defects in 78 patients. The results from two modalities were then compared with surgical findings for the purpose of assessing the diagnostic value of AVSS. Statistics showed that surgeries identified 38 small, 23 medium and 17 large incisional hernias. The results of AVSS completely agreed with surgical findings; however, HHUS misidentified nine large hernias as medium and seven medium hernias as large...
September 2014: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/24794025/management-of-giant-inferior-triangle-lumbar-hernia-petit-s-triangle-hernia-a-rare-complication-following-delayed-breast-reconstruction-with-extended-latissimus-dorsi-myocutaneous-flap
#19
Alexandre Mendonça Munhoz, Eduardo Montag, Eduardo Gustavo Arruda, Gustavo Sturtz, Rolf Gemperli
INTRODUCTION: Lumbar triangle hernia after breast reconstruction with latissimus dorsi flap (LDMF) is a very rare complication and few cases were previously described. Muscle mobilization and iatrogenic fascia defect are related etiologic factors. PRESENTATION OF CASE: The authors describe a rare case of lumbar hernia in a 58-year-old woman who underwent delayed left breast reconstruction with LDMF. Two months after surgery, a progressive symptomatic lower left lumbar bulge was observed...
2014: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/24582111/does-sevoflurane-preserve-regional-cerebral-oxygen-saturation-measured-by-near-infrared-spectroscopy-better-than-propofol
#20
RANDOMIZED CONTROLLED TRIAL
L Valencia, A Rodríguez-Pérez, B Kühlmorgen, R Y Santana
OBJECTIVE: The aim of this study was to compare the effect of sevoflurane and propofol on cerebral oxygenation, using regional cerebral oxygen saturation (SrO2) measured by near-infrared spectroscopy (NIRS). STUDY DESIGN: Prospective, randomized, controlled study. PATIENTS AND METHODS: Fifty-four patients aged between 18 and 65 years who underwent elective minor surgery (tumorectomy for breast cancer or inguinal hernia repair) were randomly assigned to receive sevoflurane or propofol anaesthesia...
April 2014: Annales Françaises D'anesthèsie et de Rèanimation
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