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https://www.readbyqxmd.com/read/28648038/-effects-of-na-h-exchanger-1-inhibitor-on-intestinal-injury-of-rats-with-burn-sepsis-and-the-mechanism
#1
W P Li, G Y Zhao, X K Yang
Objective: To observe the effects of Na(+) /H(+) exchanger 1 (NHE1) inhibitor on intestinal injury of rats with burn sepsis, and to explore the possible mechanism preliminarily. Methods: Ninety SD rats were divided into control group, pure sepsis group, and NHE1 inhibitor group according to the random number table, with 30 rats in each group. Full-thickness scald (hereinafter referred to as burn) model with 20% total body surface area were reproduced on the back of rats in pure sepsis and NHE1 inhibitor groups, and then 50 μL liquid of Pseudomonas aeruginosa ATCC 27853 (2×10(5) colony forming unit/mL) were injected into the center of wounds on the back...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28648016/-mechanisms-of-cytoskeleton-and-pi3k%C3%AE-rhoa-in-fine-particulate-matter-deteriorating-phagocytosis-defect-of-alveolar-macrophage-in-mice-with-chronic-obstructive-pulmonary-disease
#2
Q Xia, S T Hu, X L Zeng, H R Bao, X J Liu
Objective: To explore the mechanism of cytoskeleton and PI3Kδ-RhoA in fine particulate matter deteriorating phagocytosis defect of alveolar macrophage (AM) in chronic obstructive pulmonary disease (COPD) mice. Methods: Forty mice were randomly divided into four groups: health control group, COPD group, health PM2.5 group, COPD PM2.5 group and with ten in each group. A mouse model of COPD was established by cigarette smoke exposure, and health PM2.5 group and COPD PM2.5 group mice were given PM2.5 (588 μg/m(3)) aerosol inhalation for 90 days...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28648015/-therapeutic-effects-of-tubastatin-a-hcl-on-airway-inflammation-in-acute-mice-asthma-model
#3
X M Su, Y Ren, M L Li, X Zhao, J Kang
Objective: To investigated the therapeutic effects of Tubastatin A Hcl, a selective HDAC6 inhibitor, on airway inflammation in acute mice bronchial asthma (asthma) model. Methods: A total of 48 BALB/C mice were randomly divided into control group, asthma group, dexamethasone group and Tubastatin A Hcl group with 12 mice in each group. Then the airway hyperresponsiveness was assessed in each group; total cell number, different cell number, levels of Interleukin (IL)-4, IL-5 and Interferon-γ (IFN-γ) in the bronchoalveolar lavage fluid (BALF) were detected; the lung tissues of each group were stained with HE to observe the inflammatory cells infiltration...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28648012/-validation-of-the-caprini-risk-assessment-model-for-venous-thromboembolism-in-chinese-hospitalized-patients-in-a-general-hospital
#4
X Y Luo, F X Zhang
Objective: To assess the validity of Caprini risk assessment model in prediction of venous thromboembolism in Chinese hospitalized patients in a general hospital. Methods: Medical record review was performed in Beijing Shijitan Hosital for all eligible hospitalized patients who underwent screening for venous thromboembolism between January and December 2015. The Caprini score of patients with or without venous thromboemboilism and incidence of venous thromboembolism in patients with various Caprini risk levels, surgery and medical patients was compared...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28648007/-current-status-and-prospect-of-colorectal-cancer-in-precision-medical-model
#5
X S Wang
No abstract text is available yet for this article.
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28648005/-components-of-human-placental-extract-and-its-protective-effect-to-rat-from-d-galn-induced-acute-liver-injury
#6
H Q Lei, M L Cheng, J Li, P P Zhou, X H Luo, F Yu
Objective: To evaluate the effect of human placental extracts (HPE) on the protection from acute liver injury (ALI) induced by D-GalN and analyze the components of HPE. Methods: (1)Fourty male mice were randomly divided into five groups (Blank, Model, MgIG, HPE and HPE+ MgIG) for the ALI model and treatments.The serum alanine aminotransferase (ALT) and aspartate transaminase (AST) were determined by biochemical assays.Nitric monoxide (NO), malondialdehyde (MDA), superoxide dismutase (SOD), total antioxidant capacity (T-AOC) in serum and hepatic tissue were detected by assay kits...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28648004/-effects-of-botulinum-toxin-type-a-injection-for-pathological-characteristic-of-calf-in-rats-with-spinal-cord-injure
#7
X M Wei, Z L Dou, Y W Zhang, M Dai, F Yu, Q Y Wang, L Jiang
Objective: To explore the effect of BoTN-A on pathological characteristics of calf (GM) and motor function of ankle dorsiflexors in SCI model rats. Methods: Thirty-six SD male rats (weight 260-280 g) were randomly allocated into normal control group and 12w-control group, NS-injection group and BT-injection group in this study.NS/BT-injection groups were divided into two subgroups separately (2w-NS, 2w-BT, 8w-NS, 8w-BT). No injection was applied in normal control group or 12w-control group.Saline/BoTN-A was injected in right GM in NS/BT-injection group at two different time points(2w, 8w)...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647989/-accuracy-of-ct-colonography-for-the-detection-of-colorectal-neoplasm-a-subgroup-meta-analysis
#8
H H Yu, H Y Huang, Y S Jiang, C Zhu, C G Guo, M Dai, X J Xing, J F Shi
Objective: To assess the accuracy of computed tomographic colonography (CTC) for detection of colorectal neoplasm. Methods: Publications prior to January 2016 from the Medline, Embase, CNKI, WANFANG, and VIP literature databases were systematically reviewed. A QUADAS checklist was used to assess the quality of the studies. According to the sizes of tumor (≥6 mm or ≥10 mm), diagnostic test accuracy indexes (area under the curve, sensitivity and specific) were pooled and stratified. Spearman correlation and curve of summary receiver operating characteristic (SROC) were applied to comprehensively assess the threshold effect...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647974/-cd-4-t-lymphocyte-responses-to-anti-retroviral-therapy-among-hiv-aids-patients-aged-18-and-over
#9
X X Guo, Y Ma, Z H Dou, Y S Wu, D C Zhao, W P Cai, Y Li, X X Dong
Objective: To compare the differences of CD(4) (+) T lymphocyte (CD(4)) counts between patients aged 18 and over, to explore the effect of age on treatment, 36 months after having received the China National Free AIDS Antiretroviral Treatment on HIV/AIDS. Methods: Through the National ART Information Ssystem, we selected those HIV/AIDS patients who initiated the ART 36 months after the ART, between January 1, 2010 and December 31, 2012 in Guangzhou, Liuzhou and Kunming. Patients were divided into age groups as 18-49, 50-59 and 60 or over year olds, at the baseline of treatment...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647969/-knowledge-attitude-and-practice-to-chronic-diseases-and-associated-influencing-factors-in-uygur-population-in-kashgar-area-of-xinjiang-uygur-autonomous-region
#10
Z B Zhang, Z X Xue, M M Ma, Y H Li, D M Luo, X L Song, X F Chao, G Wang, Nurmamat Nazibam, Bawudun Ayxamgul, Mahat Sulayman, X J Wu, Z Y Zhou, B S Sun, Y Z Wang, M Wang
Objective: To investigate the knowledge, attitude and practice (KAP) to chronic diseases and associated influencing factors in Uygur adults in Kashgar of southern Xinjiang, and provide basic information for developing ethnic specific prevention and control strategies for chronic diseases. Methods: With stratified cluster random sampling, investigations, including questionnaire survey, physical examination and laboratory tests were performed among local residents who were aged ≥18 years and selected in Shufu county in southern Xinjiang...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647968/-prevalence-of-hypertension-and-risk-factors-in-uygur-population-in-kashgar-area-of-xinjiang-uygur-autonomous-region
#11
Z B Zhang, Z X Xue, H Y Chen, T M Wang, Y H Li, X F Chao, G Wang, D M Luo, X J Wu, Nurmamat Nazibam, Bawudun Ayxamgul, Elyas Gulbahar, Z Y Zhou, B S Sun, Y Z Wang, M Wang
Objective: To investigate the prevalence of hypertension and risk factors in Uygur adults in Kashgar of Xinjiang. Methods: A total of 4 748 Uygur adults aged ≥18 years selected through cluster random sampling in Shufu county of Kashgar prefecture were surveyed by means of questionnaire survey, physical examination and laboratory test. The prevalence, awareness, treatment and control rate of hypertension of different groups were calculated and risk factors of hypertension was analyzed by using non-conditional logistic regression model...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647966/-prevalence-of-diabetes-mellitus-and-associated-risk-factors-in-uygur-population-in-kashgar-area-of-xinjiang-uygur-autonomous-region
#12
Z B Zhang, Z X Xue, H Wang, T M Wang, Y H Li, X L Song, X F Chao, G Wang, X J Wu, Nurmamat Nazibam, Bawudun Ayxamgul, Elyas Gulbahar, Z Y Zhou, B S Sun, Y Z Wang, M Wang
Objective: To investigate the epidemiologic characteristics of diabetes mellitus (DM) in Uygur residents in Kashgar of Xinjiang. Methods: The survey was conducted among the Uygur residents aged ≥18 years selected through stratified cluster sampling in Kashgar by means of questionnaire survey, physical examination and basic laboratory test. The prevalence of different groups were calculated and risk factors of DM was analyzed by logistic vegression model. Results: A total of 4 608 adults were surveyed. The prevalence of DM was 11...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647933/a-new-system-of-documentation-to-improve-dietitian-physician-crosstalk
#13
Shelly Rachman-Elbaum, Aliza H Stark, Josefa Kachal, Teresa W Johnson, Bat Sheva Porat-Katz
BACKGROUND: Standardization of the dietetic care process allows for early identification of malnutrition and metabolic disorders, interdisciplinary collaboration among the medical team, and improved quality of patient care. Globally, dietitians are adopting a nutrition care model that integrates national regulations with professional scope of practice. Currently, Israel lacks a standardized dietetic care process and documentation terminology. OBJECTIVES: To assess the utilization of a novel sectoral documentation system for nutrition care in Israel...
June 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28647925/psychobehavioral-effects-of-meditation
#14
Mieczyslaw Pokorski, Anna Suchorzynska
Meditation is an increasingly popular psychobehavioral therapy. Various meditation techniques in use make it hard to objectively scrutinize the psychological benefits. Therefore, in this study we set out to examine the effects of two fundamentally different meditative techniques, Zazen, 'seated meditation', in which the body and mind are calmed, and Tai Chi, 'meditation in motion', based on energetic martial art performance. The aim was to compare the effects of both techniques on personality structure, emotional intelligence, mood, and coping with stress...
June 25, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28647924/comparative-expression-analysis-of-rice-and-arabidopsis-peroxiredoxin-genes-suggests-conserved-or-diversified-roles-between-the-two-species-and-leads-to-the-identification-of-tandemly-duplicated-rice-peroxiredoxin-genes-differentially-expressed-in-seeds
#15
Yun-Shil Gho, Sun-A Park, Sung-Ruyl Kim, Anil Kumar Nalini Chandran, Gynheung An, Ki-Hong Jung
BACKGROUND: Peroxiredoxins (PRXs) have recently been identified as plant antioxidants. Completion of various genome sequencing projects has provided genome-wide information about PRX genes in major plant species. Two of these -- Oryza sativa (rice) and Arabidopsis -- each have 10 PRX members. Although significant progress has been made in understanding their biological roles in Arabidopsis, those functions in rice, a model crop plant, have not been well studied. RESULTS: We performed a comparative expression analysis of rice and Arabidopsis PRXs...
December 2017: Rice
https://www.readbyqxmd.com/read/28647922/comparison-of-quality-of-chest-compressions-during-training-of-laypersons-using-push-heart-and-little-anne-manikins-using-blinded-cprcards
#16
Shota Tanaka, Alexander E White, Ryo Sagisaka, Guanseng Chong, Eileen Ng, Jinny Seow, Nurul Asyikin Mj, Hideharu Tanaka, Marcus Eng Hock Ong
BACKGROUND: Mass Cardio-Pulmonary Resuscitation (CPR) training using less expensive and easily portable manikins is one way to increase the number of trained laypeople in a short time. The easy-to-carry, low-cost CPR training model called Push Heart (PH) is widely used in Japan. The aim of this study was to examine if PH can achieve chest compression quality that is similar to that using more conventional Little Anne (LA) manikins for training laypersons. METHODS: This prospective randomized crossover study was done during routine community CPR training of laypersons in Singapore...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28647915/impact-of-the-21-gene-recurrence-score-on-outcome-in-patients-with-invasive-lobular-carcinoma-of-the-breast
#17
Scott Kizy, Jing Li Huang, Schelomo Marmor, Todd M Tuttle, Jane Yuet Ching Hui
PURPOSE: Invasive lobular carcinoma (ILC) of the breast has unique clinicopathologic characteristics, compared to invasive ductal carcinoma. The role of the 21-gene Recurrence Score (RS) has not been clearly defined for ILC. We sought to determine the prognostic value of RS and the impact of adjuvant chemotherapy on long-term survival in patients with ILC. METHODS: Utilizing the Surveillance, Epidemiology and End Results database from 2004 to 2013, we identified records of women aged 18-74 years, diagnosed with estrogen receptor (ER)-positive ILC (stage I to III) with RS available...
June 24, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28647913/how-adaptation-makes-low-firing-rates-robust
#18
Arthur S Sherman, Joon Ha
Low frequency firing is modeled by Type 1 neurons with a SNIC, but, because of the vertical slope of the square-root-like f-I curve, low f only occurs over a narrow range of I. When an adaptive current is added, however, the f-I curve is linearized, and low f occurs robustly over a large I range. Ermentrout (Neural Comput. 10(7):1721-1729, 1998) showed that this feature of adaptation paradoxically arises from the SNIC that is responsible for the vertical slope. We show, using a simplified Hindmarsh-Rose neuron with negative feedback acting directly on the adaptation current, that whereas a SNIC contributes to linearization, in practice linearization over a large interval may require strong adaptation strength...
December 2017: Journal of Mathematical Neuroscience
https://www.readbyqxmd.com/read/28647909/organic-matter-export-to-the-seafloor-in-the-baltic-sea-drivers-of-change-and-future-projections
#19
Tobias Tamelander, Kristian Spilling, Monica Winder
The impact of environmental change and anthropogenic stressors on coastal marine systems will strongly depend on changes in the magnitude and composition of organic matter exported from the water column to the seafloor. Knowledge of vertical export in the Baltic Sea is synthesised to illustrate how organic matter deposition will respond to climate warming, climate-related changes in freshwater runoff, and ocean acidification. Pelagic heterotrophic processes are suggested to become more important in a future warmer climate, with negative feedbacks to organic matter deposition to the seafloor...
June 24, 2017: Ambio
https://www.readbyqxmd.com/read/28647908/cmv-immune-evasion-and-manipulation-of-the-immune-system-with-aging
#20
REVIEW
Sarah E Jackson, Anke Redeker, Ramon Arens, Debbie van Baarle, Sara P H van den Berg, Chris A Benedict, Luka Čičin-Šain, Ann B Hill, Mark R Wills
Human cytomegalovirus (HCMV) encodes numerous proteins and microRNAs that function to evade the immune response and allow the virus to replicate and disseminate in the face of a competent innate and acquired immune system. The establishment of a latent infection by CMV, which if completely quiescent at the level of viral gene expression would represent an ultimate in immune evasion strategies, is not sufficient for lifelong persistence and dissemination of the virus. CMV needs to reactivate and replicate in a lytic cycle of infection in order to disseminate further, which occurs in the face of a fully primed secondary immune response...
June 24, 2017: GeroScience
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