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Prenatal depression

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https://www.readbyqxmd.com/read/28440816/influences-of-prenatal-and-postnatal-maternal-depression-on-amygdala-volume-and-microstructure-in-young-children
#1
D J Wen, J S Poh, S N Ni, Y-S Chong, H Chen, K Kwek, L P Shek, P D Gluckman, M V Fortier, M J Meaney, A Qiu
Maternal depressive symptoms influence neurodevelopment in the offspring. Such effects may appear to be gender-dependent. The present study examined contributions of prenatal and postnatal maternal depressive symptoms to the volume and microstructure of the amygdala in 4.5-year-old boys and girls. Prenatal maternal depressive symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS) at 26 weeks of gestation. Postnatal maternal depression was assessed at 3 months using the EPDS and at 1, 2, 3 and 4...
April 25, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28433458/linking-the-biological-underpinnings-of-depression-role-of-mitochondria-interactions-with-melatonin-inflammation-sirtuins-tryptophan-catabolites-dna-repair-and-oxidative-and-nitrosative-stress-with-consequences-for-classification-and-cognition
#2
REVIEW
George Anderson
The pathophysiological underpinnings of neuroprogressive processes in recurrent major depressive disorder (rMDD) are reviewed. A wide array of biochemical processes underlie MDD presentations and their shift to a recurrent, neuroprogressive course, including: increased immune-inflammation, tryptophan catabolites (TRYCATs), mitochondrial dysfunction, aryl hydrocarbonn receptor activation, and oxidative and nitrosative stress (O&NS), as well as decreased sirtuins and melatonergic pathway activity. These biochemical changes may have their roots in central, systemic and/or peripheral sites, including in the gut, as well as in developmental processes, such as prenatal stressors and breastfeeding consequences...
April 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28419444/a-self-determination-theory-perspective-on-postpartum-depressive-symptoms-and-early-parenting-behaviors
#3
Katrijn Brenning, Bart Soenens
OBJECTIVE: On the basis of self-determination theory, this study investigates longitudinal associations between satisfaction and frustration mothers' basic psychological needs (i.e., autonomy, relatedness, competence) and mothers' postnatal depressive symptoms and early parenting behaviors. METHOD: Participants were 214 women assessed during their pregnancy (Time 1), 4 months after delivery (Time 2), and when the child was 2 years old (Time 3). RESULTS: Results demonstrate effects of prenatal basic psychological needs (needs frustration more specifically) on postnatal depressive symptoms...
April 17, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28418941/prenatal-fluoxetine-modifies-the-behavioral-and-hormonal-responses-to-stress-in-male-mice-role-for-glucocorticoid-insensitivity
#4
Ronit Avitsur
Women with major depressive disorder during pregnancy often use selective serotonin reuptake inhibitors (SSRIs) antidepressants. These drugs readily cross the placental barrier and impact the developing fetal brain. Recently, we reported that prenatal fluoxetine (FLX), an SSRI antidepressant drug, altered corticosterone and behavioral responses to stress in female mouse offspring. The present study assessed the effects of prenatal FLX on these responses in males. The results showed that prenatal FLX significantly augmented the corticosterone response to acute stress in young prepubescent mice...
April 17, 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/28417515/do-maternal-depression-and-anxiety-influence-children-s-oral-health-related-quality-of-life
#5
Francine Dos Santos Costa, Marina Sousa Azevedo, Thiago Machado Ardenghi, Ricardo Tavares Pinheiro, Flávio Fernando Demarco, Marília Leão Goettems
OBJECTIVE: This study aimed to investigate the influence of depressive and anxiety symptoms in young mothers on their perception in relation to their children's oral health-related quality of life (COHRQoL). METHODS: This cross-sectional study was carried out in Pelotas, Southern Brazil, and it was nested in a cohort of adolescent mothers having their prenatal care in public health service, starting in 2008. When the children were aged 24-36 months, they and their mothers were interviewed and submitted to clinical examination by a trained team...
April 17, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28412876/effect-of-breastfeeding-on-postpartum-depressive-symptoms-among-adolescent-and-young-adult-mothers
#6
Heather L Sipsma, Elizabeth Ruiz, Krista Jones, Urania Magriples, Trace Kersahw
PURPOSE: To describe the association between breastfeeding and postpartum depressive symptoms among a sample of adolescent and young adult mothers and to determine whether breastfeeding difficulty moderates this association. MATERIALS AND METHODS: Data were derived from a prospective cohort of pregnant adolescent and young adult females (ages 14-21) as they transitioned to parenthood. This analysis uses data collected during pregnancy and at 6 months postpartum among mothers (n = 137) who initiated breastfeeding...
April 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28410627/polyunsaturated-fatty-acids-in-perinatal-depression-a-systematic-review-and-meta-analysis
#7
Pao-Yen Lin, Cheng-Ho Chang, Mary Foong-Fong Chong, Helen Chen, Kuan-Pin Su
BACKGROUND: Omega-3 (or n-3) polyunsaturated fatty acids (PUFAs) are promising antidepressant treatments for perinatal depression (PND) because of supporting evidence from clinical trials, the advantage in safety, and their anti-inflammatory and neuroplastic effects. Although several observational studies have shown n-3 PUFA deficits in women with PND, the results of individual PUFAs from different studies were inconsistent. METHODS: This systematic review and meta-analysis aims to compare the levels of PUFA indices, including eicosapentaenoic acid, docosahexaenoic acid, arachidonic acid, total n-3, total n-6, and the n-6/n-3 ratio between women with PND and healthy control subjects...
March 9, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28403801/iga-igm-responses-to-gram-negative-bacteria-are-not-associated-with-perinatal-depression-but-with-physio-somatic-symptoms-and-activation-of-the-tryptophan-catabolite-pathway-at-the-end-of-term-and-postnatal-anxiety
#8
Roomruangwong Chutima, Buranee Kanchanatawan, Sunee Sirivichayakul, George Anderson, André F Carvalho, Sebastien Duleu, Michel Geffard, Michael Maes
Evidence has implicated the translocation of commensal Gram-negative bacteria (Gram-B) due to leaky gut in the pathophysiology of depression and physio-somatic symptoms (e.g. fatigue, pain, irritable bowel syndrome, malaise, etc.). In addition, the leaky gut may contribute to immune-inflammatory activation and oxidative stress. This study investigated whether bacterial translocation is associated with perinatal depression and anxiety scores and with prenatal physio-somatic symptoms and immune-inflammatory biomarkers, including the tryptophan catabolite (TRYCAT) pathway...
April 7, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28403471/do-psychiatric-disorders-or-measures-of-distress-moderate-response-to-postpartum-relapse-prevention-interventions
#9
Rachel P Kolko, Rebecca L Emery, Yu Cheng, Michele D Levine
Introduction: Most women who quit smoking during pregnancy will relapse postpartum. Interventions for sustained postpartum abstinence can benefit from understanding prenatal characteristics associated with treatment response. Given that individuals with psychiatric disorders or elevated depressive symptoms have difficulty quitting smoking and that increases in depressive symptoms prenatally are common, we examined the relevance of psychiatric diagnoses, prenatal depressive symptoms, and stress to postpartum relapse prevention intervention response...
May 1, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28402697/the-prenatal-distress-measure-adaptation-of-the-postpartum-distress-measure-for-a-prenatal-sample
#10
Niela M Hirsch, Randy Fingerhut, Kelly C Allison
BACKGROUND: Pregnancy is a significant transition period for women that can be markedly stressful. The presence of elevated depressed mood and anxiety during pregnancy places mothers, fetuses, and neonates at greater risk for developing biological and psychological difficulties. It appears that no general measures of distress currently exist that can be used to screen for both prenatal anxiety and mood. MATERIALS AND METHODS: This study explores the applicability of postpartum distress measure (PDM), a validated general distress postpartum screening tool, in a prenatal sample...
April 12, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28397629/the-impact-of-life-stress-on-adult-depression-and-anxiety-is-dependent-on-gender-and-timing-of-exposure
#11
Carly E Herbison, Karina Allen, Monique Robinson, John Newnham, Craig Pennell
There is debate about the relative importance of timing of stressful events prenatally and over the life course and risk for subsequent depressive/anxious illness. The aim of this study was to examine the relative roles of prenatal stress and postnatal stress trajectories in predicting depression and anxiety in early adulthood in males and females. Exposure to life stress events was examined in the Western Australian Pregnancy Cohort (Raine) Study during pregnancy and ages 1, 2, 3, 5, 8, 10, 14, and 17 years...
April 11, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28395974/antidepressant-like-activity-of-icariin-mediated-by-group-i-mglurs-in-prenatally-stressed-offspring
#12
Xiaoxiao Zhang, Hongli Sun, Qian Su, Tianwei Lin, Huiping Zhang, Junli Zhang, Shaokang Dang, Zhongliang Zhu
OBJECTIVE: The present study was performed to identify antidepressant-like activity of icariin in prenatally stressed male rats. METHODS: The effects of icariin on PRS-induced depression were examined using sucrose preference test (SPT) and forced swimming test (FST) in male offspring, and measuring protein and mRNA expressions of group I mGluRs receptors and EAAT2 via western blotting and quantitative real-time PCR assays. RESULTS: The results indicated that prenatal restraint stress (PRS) resulted in several behavioral anomalies...
April 7, 2017: Brain & Development
https://www.readbyqxmd.com/read/28393324/maternal-prenatal-stress-and-other-developmental-risk-factors-for-adolescent-depression-spotlight-on-sex-differences
#13
Seth D Maxwell, Anna M Fineberg, Deborah A Drabick, Shannon K Murphy, Lauren M Ellman
Maternal stress during pregnancy has been linked to premorbid abnormalities associated with depression (e.g., difficult temperament, cognitive deficits) in offspring. However, few studies have looked across developmental periods to examine maternal stress during pregnancy and offspring depression during adolescence and whether these associations differ by sex. The current study used data from 1711 mother-offspring dyads (offspring sex: 49.8% male) in a longitudinal birth cohort study. Maternal narratives collected during pregnancy were qualitatively coded for stress-related themes by independent raters...
April 10, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28393063/neuropsychological-and-psychiatric-outcomes-in-dextro-transposition-of-the-great-arteries-across-the-lifespan-a-state-of-the-art-review
#14
REVIEW
Leila Kasmi, Damien Bonnet, Michèle Montreuil, David Kalfa, Nikoletta Geronikola, David C Bellinger, Johanna Calderon
Advances in prenatal diagnosis, perioperative management, and postoperative care have dramatically increased the population of survivors of neonatal and infant heart surgery. The high survival rate of these patients into adulthood has exposed the alarming prevalence of long-term neuropsychological and psychiatric morbidities. Dextro-transposition of the great arteries (d-TGA) is one of the most extensively studied cyanotic congenital heart defect (CHD) with regard to neurodevelopmental outcomes. Landmark studies have described a common neurodevelopmental and behavioral phenotype associated with d-TGA...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28392956/effects-of-herbal-medicine-gan-mai-da-zao-decoction-on-several-types-of-neuropsychiatric-disorders-in-an-animal-model-a-systematic-review-herbal-medicine-for-animal-studies-of-neuropsychiatric-diseases
#15
REVIEW
Su Ran Kim, Hye Won Lee, Ji Hee Jun, Byoung-Seob Ko
OBJECTIVES: Gan Mai Da Zao (GMDZ) decoction is widely used for the treatment of various diseases of the internal organ and of the central nervous system. The aim of this study is to investigate the effects of GMDZ decoction on neuropsychiatric disorders in an animal model. METHODS: We searched seven databases for randomized animal studies published until April 2015: Pubmed, four Korean databases (DBpia, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, and Research Information Sharing Service), and one Chinese database (China National Knowledge Infrastructure)...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28389421/pregnant-women-s-views-on-the-feasibility-and-acceptability-of-web-based-mental-health-e-screening-versus-paper-based-screening-a-randomized-controlled-trial
#16
Dawn Kingston, Marie-Paule Austin, Sander Veldhuyzen van Zanten, Paula Harvalik, Rebecca Giallo, Sarah D McDonald, Glenda MacQueen, Lydia Vermeyden, Gerri Lasiuk, Wendy Sword, Anne Biringer
BACKGROUND: Major international guidelines recommend mental health screening during the perinatal period. However, substantial barriers to screening have been reported by pregnant and postpartum women and perinatal care providers. E-screening offers benefits that may address implementation challenges. OBJECTIVE: The primary objective of this randomized controlled trial was to evaluate the feasibility and acceptability of Web-based mental health e-screening compared with paper-based screening among pregnant women...
April 7, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28389369/prenatal-stress-and-depression-associated-neuronal-development-in-neonates
#17
REVIEW
Mahino Fatima, Saurabh Srivastav, Amal Chandra Mondal
Prenatal maternal depression has its direct effects on early brain development deficits with permanent changes in neuroendocrine functions and impaired behavior in offsprings. Prenatal stress (PS) transmits its affect on developing fetus and on pregnancy outcomes in adult offsprings. This results in impaired neurodevelopment, delayed cognitive and motor development with impaired behavior towards stressful conditions. There are sufficient evidences in animal models suggesting depression responsive hypothalamic-pituitary-adrenal (HPA) axis and its hormonal response via cortisol, responsible for its critical effects in both the mother and offspring...
April 4, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28383374/using-a-patient-navigator-to-improve-postpartum-care-in-an-urban-women-s-health-clinic
#18
Lynn M Yee, Noelle G Martinez, Antoinette T Nguyen, Nadia Hajjar, Melissa J Chen, Melissa A Simon
OBJECTIVE: To estimate whether postpartum visit attendance was improved in women exposed to a postpartum patient navigation program compared with those who received care immediately before the program's initiation and to assess whether other postpartum health behaviors improved during the intervention period. METHODS: This is a prospective observational study of women enrolled in a patient navigation program compared with women receiving care before the program...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28383321/antidepressive-like-effect-of-imperatorin-from-angelica-dahurica-in-prenatally-stressed-offspring-rats-through-5-hydroxytryptamine-system
#19
Yanjun Cao, Jiahui Liu, Qiong Wang, Minghui Liu, Ying Cheng, Xiaoxiao Zhang, Tianwei Lin, Zhongliang Zhu
Adolescence is a time of continued brain maturation, particularly in limbic and cortical regions, which undoubtedly plays a role in the physiological and emotional changes. Prenatally stressed offspring rats were used to investigate the potential antidepressive-like effects of imperatorin (IMP) extracted from the root of radix angelica. After 4 weeks of treatment of IMP, behavioral tests (sucrose-preference test, forced-swimming test, and open-field test) were measured. 5-hydroxytryptamine (5-HT) concentration in the hippocampus and frontal cortex was measured using an enzyme-linked immunosorbent assay...
May 24, 2017: Neuroreport
https://www.readbyqxmd.com/read/28379837/tokophobia-fear-of-childbirth-prevalence-and-risk-factors
#20
Karin Demšar, Matija Svetina, Ivan Verdenik, Natasa Tul, Isaac Blickstein, Vislava Globevnik Velikonja
OBJECTIVE: To identify the prevalence of and to determine the risk factors for developing a fear of childbirth (tokophobia). METHODS: We evaluated 191 pregnant women during Parenting and Childbirth Classes. Participants were approached when attending Parenting and Childbirth Classes between June 2014 and September 2014 and were asked to complete several questionnaires related to depression (CES-D), anxiety (STAI X1 and X2), satisfaction with life (SWLS), delivery expectation/experience (W-DEQ), and specific fears...
April 5, 2017: Journal of Perinatal Medicine
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