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Prenatal depression

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https://www.readbyqxmd.com/read/29231186/-psychometric-properties-of-postpartum-depression-predictors-inventory-revised-prenatal-version-in-a-sample-of-spanish-pregnant-women
#1
María de la Fe Rodríguez-Muñoz, Laura Vallejo Slocker, María Eugenia Olivares Crespo, Nuria Izquierdo Méndez, Cristina Soto, Huynh-Nhu Le
OBJECTIVE: Prenatal depression is a major public health problem, therefore predicting and preventing it is a relevant objective for public health agendas. Consequently, it is important to have adequate screening tools to detect risk factors associated with prenatal depression. The aim of this study was to evaluate the psychometric properties reliability and factor structure of the Spanish version of the Postpartum Depression Predictors Inventory- Revised- Prenatal Version (PDI-R) in pregnant women who attend prenatal care in an urban hospital in Spain...
December 4, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/29186532/loss-of-offspring-peg3-reduces-neonatal-ultrasonic-vocalisations-and-increases-maternal-anxiety-in-wild-type-mothers
#2
G I McNamara, H D J Creeth, D J Harrison, K E Tansey, R M Andrews, A R Isles, R M John
Depression and anxiety are the most common mental health conditions during pregnancy and can impair the normal development of mother-infant interactions. These adversities are associated with low birth weight and increased risk of behavioural disorders in children. We recently reported reduced expression of the imprinted gene PATERNALLY EXPRESSED GENE 3 (PEG3) in placenta of human infants born to depressed mothers. Expression of Peg3 in brain has previously been linked maternal behaviour in rodents, at least in some studies, with mutant dams neglecting their pups...
November 24, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29186413/antenatal-paternal-adjustment-and-paternal-attitudes-after-infertility-treatment
#3
T M Pinto, C Samorinha, I Tendais, S Silva, B Figueiredo
STUDY QUESTION: Do mode of conception [ART versus Natural (NC)] and depression have an interactive effect on antenatal paternal adjustment and paternal attitudes? SUMMARY ANSWER: Depression increased the negative effect of ART on antenatal paternal adjustment and paternal attitudes, specifically on antenatal marital relationship satisfaction. WHAT IS KNOWN ALREADY: Research on antenatal paternal adjustment and paternal attitudes after ART is scarce and has produced inconsistent results...
November 24, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29183765/developmental-expression-of-anxiety-and-depressive-behaviours-after-prenatal-predator-exposure-and-early-life-homecage-enhancement
#4
Amanda Green, Michael J Esser, Tara S Perrot
Stressful events during gestation can have sex-specific effects on brain and behavior, and may contribute to some of the differences observed in adult stress responding and psychopathology. We investigated the impact of a novel repeated prenatal psychological stress (prenatal predator exposure - PPS) during the last week of gestation in rats on offspring behaviours related to social interaction (play behaviour), open field test (OFT), forced swim test (FST) and sucrose preference test (SP) during the juvenile period and in adulthood...
November 25, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29182556/long-term-depression-in-rat-hippocampus-and-the-effect-of-ethanol-during-fetal-life
#5
REVIEW
Olivier Pierrefiche
Alcohol (ethanol) disturbs cognitive functions including learning and memory in humans, non-human primates, and laboratory animals such as rodents. As studied in animals, cellular mechanisms for learning and memory include bidirectional synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD), primarily in the hippocampus. Most of the research in the field of alcohol has analyzed the effects of ethanol on LTP; however, with recent advances in the understanding of the physiological role of LTD in learning and memory, some authors have examined the effects of ethanol exposure on this particular signal...
November 28, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29171010/prenatal-exposure-to-ketamine-in-rats-implications-on-animal-models-of-schizophrenia
#6
Carlos M Coronel-Oliveros, Renny Pacheco-Calderón
Schizophrenia is a complex neuropsychiatric disorder characterized by hallucinations, delusions, anhedonia, flat affect and cognitive impairments. The aim of this study was to propose a prenatal treatment with ketamine, a psychedelic drug that acts as a non-competitive inhibitor of glutamate NMDA receptors, as a neurodevelopmental animal model of schizophrenia. The drug was applied (i.m. 60 mg.kg(-1)  h(-1) ) in pregnant Sprague-Dawley rats on gestational Day 14. Offspring behavior was studied on pubertal (4 weeks old) and adult (10 weeks old) stages...
November 24, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/29164970/a-feasibility-study-of-trauma-sensitive-obstetric-care-for-low-income-ethno-racial-minority-pregnant-abuse-survivors
#7
N R Stevens, T A Lillis, L Wagner, V Tirone, S E Hobfoll
PURPOSE: This study evaluated the feasibility and acceptability of an integrated (psychological and obstetric) intervention for pregnant abuse survivors with posttraumatic stress symptoms (PTS) from low-income, ethno-racial minority backgrounds. METHODS: Trauma-sensitive obstetrics to promote control, anxiety-reduction and empowerment (TO-CARE) offers cognitive-behavioral therapy (CBT) coping skills delivered over six sessions by therapists, coupled with trauma-sensitive obstetric care from specially-trained obstetric physicians...
November 22, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29163165/the-modulatory-properties-of-chronic-antidepressant-drugs-treatment-on-the-brain-chemokine-chemokine-receptor-network-a-molecular-study-in-an-animal-model-of-depression
#8
Ewa Trojan, Joanna Ślusarczyk, Katarzyna Chamera, Katarzyna Kotarska, Katarzyna Głombik, Marta Kubera, Agnieszka Basta-Kaim
An increasing number of studies indicate that the chemokine system may be the third major communication system of the brain. Therefore, the role of the chemokine system in the development of brain disorders, including depression, has been recently proposed. However, little is known about the impact of the administration of various antidepressant drugs on the brain chemokine - chemokine receptor axis. In the present study, we used an animal model of depression based on the prenatal stress procedure. We determined whether chronic treatment with tianeptine, venlafaxine, or fluoxetine influenced the evoked by prenatal stress procedure changes in the mRNA and protein levels of the homeostatic chemokines, CXCL12 (SDF-1α), CX3CL1 (fractalkine) and their receptors, in the hippocampus and frontal cortex...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29162172/cumulative-prenatal-exposure-to-adversity-reveals-associations-with-a-broad-range-of-neurodevelopmental-outcomes-that-are-moderated-by-a-novel-biologically-informed-polygenetic-score-based-on-the-serotonin-transporter-solute-carrier-family-c6-member-4-slc6a4
#9
Patrícia P Silveira, Irina Pokhvisneva, Carine Parent, Shirong Cai, Anu Sathyan Sathyapalan Rema, Birit F P Broekman, Anne Rifkin-Graboi, Michael Pluess, Kieran J O'Donnell, Michael J Meaney
While many studies focus on the association between early life adversity and the later risk for psychopathology, few simultaneously explore diverse forms of environmental adversity. Moreover, those studies that examined the cumulative impact of early life adversity focus uniquely on postnatal influences. The objective of this study was to focus on the fetal period of development to construct and validate a cumulative prenatal adversity score in relation to a wide range of neurodevelopmental outcomes. We also examined the interaction of this adversity score with a biologically informed genetic score based on the serotonin transporter gene...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29162171/positive-maternal-mental-health-during-pregnancy-associated-with-specific-forms-of-adaptive-development-in-early-childhood-evidence-from-a-longitudinal-study
#10
Desiree Y Phua, Michelle K Z L Kee, Dawn X P Koh, Anne Rifkin-Graboi, Mary Daniels, Helen Chen, Yap Seng Chong, Birit F P Broekman, Iliana Magiati, Neerja Karnani, Michael Pluess, Michael J Meaney
The quality of prenatal maternal mental health, from psychological stress and depressive symptoms to anxiety and other nonpsychotic mental disorders, profoundly affects fetal neurodevelopment. Despite the evidence for the influence of positive mental well-being on health, there is, to our knowledge, no research examining the possible effects of positive antenatal mental health on the development of the offspring. Using exploratory bifactor analysis, this prospective study (n = 1,066) demonstrated the feasibility of using common psychiatric screening tools to examine the effect of positive maternal mental health...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29156684/a-prenatal-interruption-of-disc1-function-in-the-brain-exhibits-a-lasting-impact-on-adult-behaviors-brain-metabolism-and-interneuron-development
#11
Dazhi Deng, Chongdong Jian, Ling Lei, Yijing Zhou, Colleen McSweeney, Fengping Dong, Yilun Shen, Donghua Zou, Yonggang Wang, Yuan Wu, Limin Zhang, Yingwei Mao
Mental illnesses like schizophrenia (SCZ) and major depression disorder (MDD) are devastating brain disorders. The SCZ risk gene, disrupted in schizophrenia 1 (DISC1), has been associated with neuropsychiatric conditions. However, little is known regarding the long-lasting impacts on brain metabolism and behavioral outcomes from genetic insults on fetal NPCs during early life. We have established a new mouse model that specifically interrupts DISC1 functions in NPCs in vivo by a dominant-negative DISC1 (DN-DISC1) with a precise temporal and spatial regulation...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29149620/the-dopamine-d4-receptor-gene-birth-weight-maternal-depression-maternal-attention-and-the-prediction-of-disorganized-attachment-at-36-months-of-age-a-prospective-gene%C3%A3-environment-analysis
#12
Justin Graffi, Ellen Moss, Alexia Jolicoeur-Martineau, Gal Moss, Vanessa Lecompte, Katherine Pascuzzo, Vanessa Babineau, Cathryn Gordon-Green, Viara R Mileva-Seitz, Klaus Minde, Roberto Sassi, Meir Steiner, James L Kennedy, Helene Gaudreau, Robert Levitan, Michael J Meaney, Ashley Wazana
BACKGROUND: Efforts to understand the developmental pathways for disorganized attachment reflect the importance of disorganized attachment on the prediction of future psychopathology. The inconsistent findings on the prediction of disorganized attachment from the dopamine D4 receptor (DRD4) gene, birth weight, and maternal depression as well as the evidence supporting the contribution of early maternal care, suggest the importance of exploring a gene by environment model. METHODS: Our sample is from the Maternal Adversity, Vulnerability, and Neurodevelopment project; consisting of 655 mother-child dyads...
November 14, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/29140822/optimizing-pregnancy-treatment-interventions-for-moms-opti-mom-a-pilot-study
#13
Gerald T Cochran, Valerie Hruschak, Walitta Abdullah, Elizabeth Krans, Antoine B Douaihy, Stephanie Bobby, Rachel Fusco, Ralph Tarter
OBJECTIVES: The public health burden of opioid use disorder (OUD) among pregnant women has significantly increased in recent years. The Optimizing Pregnancy Treatment Interventions for Moms study was a pilot project that examined the feasibility of a patient navigation (PN) intervention model to reduce substance use and improve mental health, quality of life, and to increase engagement with treatment services among pregnant women with OUD. METHODS: A 1-group repeated-measures pilot study was conducted with treatment-seeking pregnant women with opioid dependence initiating buprenorphine maintenance treatment...
November 14, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29132937/arsenic-exposure-during-embryonic-development-alters-the-expression-of-the-long-noncoding-rna-growth-arrest-specific-5-gas5-in-a-sex-dependent-manner
#14
Kevin K Caldwell, Alexander Hafez, Elizabeth Solomon, Matthew Cunningham, Andrea M Allan
Our previous studies suggest that prenatal arsenic exposure (50ppb) modifies epigenetic control of the programming of the glucocorticoid receptor (GR) signaling system in the developing mouse brain. These deficits may lead to long-lasting consequences, including deficits in learning and memory, increased depressive-like behaviors, and an altered set-point of GR feedback throughout life. To understand the arsenic-induced changes within the GR system, we assessed the impact of in utero arsenic exposure on the levels of the GR and growth arrest-specific-5 (Gas5), a noncoding RNA, across a key gestational period for GR programming (gestational days, GD 14-18) in mice...
November 10, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29122228/-depressive-symptoms-and-psychosocial-risk-factors-in-high-complexity-obstetric-patients-admitted-to-a-critical-care-obstetric-unit-in-cali-colombia
#15
Ana María Guerra, Diana María Dávalos Pérez, Alejandro Castillo Martínez
Depression is the main cause of years lossed due to disability in the world, and it affects 50% more women 50% than men. Perinatal depression has been linked with more anxiety, a chronic course, and disability than depression in other life stages. In spite of its high prevalence and serious health effects on both mother and foetus, it is frequently under-diagnosed. This study was performed on all high risk obstetric patients admitted to a critical care obstetric unit in Cali, Colombia, from January to June, 2014...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29116416/postpartum-outcomes-of-a-pilot-prenatal-care-based-psychosocial-intervention-for-ptsd-during-pregnancy
#16
Linda Weinreb, Melodie Wenz-Gross, Carole Upshur
This study examines postpartum posttraumatic stress disorder (PTSD) symptoms and secondary outcomes including postpartum depression and birth outcomes for pregnant women who screened positive for PTSD and received a psychosocial education intervention compared to women with PTSD in the usual prenatal care setting. All women entering prenatal care at two federally qualified health centers were screened for symptoms of current PTSD; one site was selected randomly to have prenatal care advocates deliver eight Seeking Safety topics for women with clinical or subclinical PTSD...
November 7, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29113038/micronutrient-dietary-intake-in-latina-pregnant-adolescents-and-its-association-with-level-of-depression-stress-and-social-support
#17
Angelie Singh, Caroline Trumpff, Jeanine Genkinger, Alida Davis, Marisa Spann, Elizabeth Werner, Catherine Monk
Adolescent pregnant women are at greater risk for nutritional deficits, stress, and depression than their adult counterparts, and these risk factors for adverse pregnancy outcomes are likely interrelated. This study evaluated the prevalence of nutritional deficits in pregnant teenagers and assessed the associations among micronutrient dietary intake, stress, and depression. One hundred and eight pregnant Latina adolescents completed an Automated Self-Administered 24-hour dietary recall (ASA24) in the 2nd trimester...
November 4, 2017: Nutrients
https://www.readbyqxmd.com/read/29110970/perinatal-weight-and-risk-of-prenatal-and-postpartum-depressive-symptoms
#18
Karen A Ertel, Tianyi Huang, Sheryl L Rifas-Shiman, Ken Kleinman, Janet Rich-Edwards, Emily Oken, Tamarra James-Todd
PURPOSE: Prepregnancy obesity and weight changes accompanying pregnancy (gestational weight gain and postpartum weight retention) may be associated with risk of maternal depressive symptoms during pregnancy and in the postpartum. The few studies that have examined these relationships report conflicting findings. METHODS: We studied pregnant (n = 2112) and postpartum (n = 1686) women enrolled in Project Viva. We used self-reported prepregnancy and postpartum weight and measured prenatal weight to calculate prepregnancy body mass index (BMI), gestational weight gain (GWG), and postpartum weight retention at 6 months after birth...
October 16, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29108161/psychological-impact-of-abortion-due-to-fetal-anomaly-a-review-of-published-research
#19
Nora Sullivan, Eoghan de Faoite
Over the past several decades, prenatal testing for fetal anomalies has become standard across the developed world. Most women who learn of a severe anomaly during pregnancy elect to terminate. The authors reviewed ten studies which examined the psychological sequelae of pregnant women following prenatal diagnoses of severe life limiting conditions. Based on the available data, the authors found evidence that women who abort due to a poor prenatal diagnosis are at higher risk of post-traumatic stress and depression than women who continue with pregnancy...
2017: Issues in Law & Medicine
https://www.readbyqxmd.com/read/29107787/marijuana-use-during-pregnancy-a-comparison-of-trends-and-correlates-among-married-and-unmarried-pregnant-women
#20
Sehun Oh, Christopher P Salas-Wright, Michael G Vaughn, Diana M DiNitto
BACKGROUND/PURPOSE: While recent evidence indicates increases in marijuana use among adult women in the United States (US), important questions remain with respect to marijuana use during pregnancy. This study examines trends and correlates of prenatal marijuana use and the effects of marijuana-specific risk/protective factors on marijuana use trends using a nationally representative sample. METHOD: Data were derived from the National Survey on Drug Use and Health (2005-2014), a nationally representative survey that included 3640 married and 3987 unmarried pregnant women in the United States...
November 2, 2017: Drug and Alcohol Dependence
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