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Prenatal anxiety

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https://www.readbyqxmd.com/read/28102595/-they-can-t-find-anything-wrong-with-him-yet-mothers-experiences-of-parenting-an-infant-with-a-prenatally-diagnosed-copy-number-variant-cnv
#1
Allison Werner-Lin, Sarah Walser, Frances K Barg, Barbara A Bernhardt
Chromosome microarray (CMA) testing is used widely in prenatal settings. Some copy number variants (CNVs) detected using CMA are associated with variable or uncertain phenotype and/or possible neurocognitive involvement. Little is known about parenting an infant following such findings. Researchers conducted interviews with 23 mothers of infants diagnosed prenatally with a potentially pathogenic CNV to elicit perspectives on the child's development and disclosure of results to others. Interviews were audiotaped and analyzed for common themes...
February 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28079434/previous-pregnancy-outcomes-and-subsequent-pregnancy-anxiety-in-a-quebec-prospective-cohort
#2
Gabriel D Shapiro, Jean R Séguin, Gina Muckle, Patricia Monnier, William D Fraser
INTRODUCTION: Pregnancy anxiety is an important psychosocial risk factor that may be more strongly associated with adverse birth outcomes than other measures of stress. Better understanding of the upstream predictors and causes of pregnancy anxiety could help to identify high-risk women for adverse maternal and infant outcomes. The objective of the present study was to measure the associations between five past pregnancy outcomes (live preterm birth (PTB), live term birth, miscarriage at <20 weeks, stillbirth at ≥20 weeks, and elective abortion) and pregnancy anxiety at three trimesters in a subsequent pregnancy...
January 12, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28070257/the-relation-of-pre-and-postnatal-depression-and-anxiety-with-exclusive-breastfeeding
#3
Farangis Sharifi, Soheila Nouraei, Ehsan Shahverdi
INTRODUCTION: Studies on the relationship between prenatal psychosocial risk factors and breastfeeding are disjointed. Maternal health status has a great influence on breastfeeding, growth, and general health of the neonates. The aim of this study was to ascertain the relation between maternal mental health and breastfeeding status of mothers in Kazerun (Fars province, Iran). METHODS: This cross-sectional study was conducted on a total of 92 pregnant women recruited from clinics in Kazerun in 2015...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28034801/testing-the-correlation-between-experimentally-induced-hypothyroidism-during-pregnancy-and-autistic-like-symptoms-in-the-rat-offspring
#4
Francesca Melancia, Michela Servadio, Sara Schiavi, Patrizia Campolongo, Alexandre Giusti-Paiva, Viviana Trezza
Thyroid hormones are important for the development of the central nervous system. Since the fetal thyroid gland is not functioning until mid-gestation, transport of maternal thyroid hormones across the placenta is essential during the early phases of gestation. Maternal thyroid deficiency has been associated with a higher incidence of neurodevelopmental disorders in the newborns. The relationship between maternal hypothyroidism and the onset of autism spectrum disorders (ASD) in the offspring, however, is still debated...
December 26, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/28027927/prenatal-stress-affects-placental-cytokines-and-neurotrophins-commensal-microbes-and-anxiety-like-behavior-in-adult-female-offspring-abbreviated-title-prenatal-stress-and-microbiome
#5
Tamar L Gur, Lena Shay, Aditi Vadodkar Palkar, Sydney Fisher, Vanessa A Varaljay, Scot Dowd, Michael T Bailey
Recent studies demonstrate that exposure to stress changes the composition of the intestinal microbiota, which is associated with development of stress-induced changes to social behavior, anxiety, and depression. Stress during pregnancy has also been related to the emergence of these disorders; whether commensal microbes are part of a maternal intrauterine environment during prenatal stress is not known. Here, we demonstrate that microbiome changes are manifested in the mother, and also found in female offspring in adulthood, with a correlation between stressed mothers and female offspring...
December 24, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28024222/effects-of-prenatal-childbirth-education-for-partners-of-pregnant-women-on-paternal-postnatal-mental-health-and-couple-relationship-a-systematic-review
#6
REVIEW
Maiko Suto, Kenji Takehara, Yumina Yamane, Erika Ota
BACKGROUND: Partner education during pregnancy may be able to prevent postnatal mental health problems, and support expectant fathers in their transition to parenthood. The aim of this systematic review is to investigate the effects of prenatal childbirth education among partners of pregnant women, particularly regarding paternal postnatal mental health and couple relationship. METHODS: We searched Medline, CINAHL, EMBASE, PsycINFO, ERIC, and CENTRAL using terms such as "partners of pregnant women," "education," and "prenatal support...
December 20, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27983596/estrogenic-endocrine-disrupting-chemicals-influencing-nrf1-regulated-gene-networks-in-the-development-of-complex-human-brain-diseases
#7
REVIEW
Mark Preciados, Changwon Yoo, Deodutta Roy
During the development of an individual from a single cell to prenatal stages to adolescence to adulthood and through the complete life span, humans are exposed to countless environmental and stochastic factors, including estrogenic endocrine disrupting chemicals. Brain cells and neural circuits are likely to be influenced by estrogenic endocrine disruptors (EEDs) because they strongly dependent on estrogens. In this review, we discuss both environmental, epidemiological, and experimental evidence on brain health with exposure to oral contraceptives, hormonal therapy, and EEDs such as bisphenol-A (BPA), polychlorinated biphenyls (PCBs), phthalates, and metalloestrogens, such as, arsenic, cadmium, and manganese...
December 13, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27978476/does-maternal-psychological-distress-affect-neurodevelopmental-outcomes-of-preterm-infants-at-a-gestational-age-of-%C3%A2-32weeks
#8
Ozlem Bozkurt, Zeynep Eras, Fatma Nur Sari, Evrim Alyamac Dizdar, Nurdan Uras, Fuat Emre Canpolat, Serife Suna Oguz
BACKGROUND: There is some evidence that maternal psychological status in the prenatal and postnatal periods is associated with infants' cognitive, behavioural, and emotional functions. AIM: The aim of this study was to examine the relationships of maternal depression and anxiety with neurodevelopmental outcomes of preterm infants with a gestational age of ≤32weeks, examined at a corrected age of 18 to 22months. STUDY DESIGN: Cross-sectional study...
December 12, 2016: Early Human Development
https://www.readbyqxmd.com/read/27977232/interpersonal-callousness-and-co-occurring-anxiety-developmental-validity-of-an-adolescent-taxonomy
#9
Alan J Meehan, Barbara Maughan, Charlotte A M Cecil, Edward D Barker
Growing evidence suggests heterogeneity within interpersonal-callous (IC) youth based on co-occurring anxiety. The developmental validity of this proposed taxonomy remains unclear however, as most previous research is cross-sectional and/or limited to adolescence. We aimed to identify low-anxiety (IC/ANX-) and high-anxiety (IC/ANX+) IC variants, and compare these groups on (a) early risk exposures, (b) psychiatric symptoms from midchildhood to early adolescence, and (c) school-based functioning. Using the Avon Longitudinal Study of Parents and Children (ALSPAC), a prospective epidemiological birth cohort, model-based cluster analysis was performed on children with complete age-13 IC and anxiety scores (n = 6,791)...
December 15, 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27965610/identification-of-socio-demographic-and-psychological-factors-affecting-women-s-propensity-to-breastfeed-an-italian-cohort
#10
Valentina E Di Mattei, Letizia Carnelli, Martina Bernardi, Chiara Jongerius, Chiara Brombin, Federica Cugnata, Anna Ogliari, Stefania Rinaldi, Massimo Candiani, Lucio Sarno
Background: Exclusive breastfeeding until 6 months postpartum is a World Health Organization objective and benefits have been demonstrated for both mother and infant. It is important to clarify which factors influence breastfeeding intentions. Our objective was to assess and identify socio-demographic and psychological factors associated with breastfeeding intention in a sample of pregnant Italian women. Materials and Methods: This prospective study included 160 pregnant women. The following psychological constructs were measured using standardized questionnaires: anxiety, prenatal attachment, adult attachment, personality traits, and intention to breastfeed...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27957315/validating-the-farsi-version-of-the-pregnancy-worries-and-stress-questionnaire-pwsq-an-exploratory-factor-analysis
#11
Fariba Navidpour, Mahrokh Dolatian, Sara Shishehgar, Farideh Yaghmaei, Hamid Alavi Majd, Seyed Saeed Hashemi
INTRODUCTION: Biological, environmental, inter- and intrapersonal changes during the antenatal period can result in anxiety and stress in pregnant women. It is pivotal to identify potential stressors and prevent their foetal and maternal consequences. The present study was conducted to validate and examine the factor structure of the Farsi version of the Pregnancy Worries and Stress Questionnaire (PWSQ). METHODS: In 2015, 502 Iranian healthy pregnant women, referred to selected hospitals in Tehran for prenatal care at 8-39 weeks of pregnancy, were recruited through a randomized cluster sampling...
October 2016: Electronic Physician
https://www.readbyqxmd.com/read/27930896/can-anxiety-tested-in-the-elevated-plus-maze-be-related-to-nociception-sensitivity-in-adult-male-rats
#12
Marie Pometlová, Anna Yamamotová, Kateryna Nohejlová, Romana Šlamberová
Methamphetamine (MA) is one of the most addictive psychostimulant drugs with a high potential for abuse. Our previous studies demonstrated that MA administered to pregnant rats increases pain sensitivity and anxiety in their adult offspring and makes them more sensitive to acute administration of the same drug in adulthood. Because individuals can differ considerably in terms of behaviour and physiology, such as rats that do not belong in some characteristics (e.g. anxiety) to average, can be described as low-responders or high-responders, are then more or less sensitive to pain...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27899401/neonatal-and-childhood-neurodevelopmental-health-and-educational-outcomes-of-children-exposed-to-antidepressants-and-maternal-depression-during-pregnancy-protocol-for-a-retrospective-population-based-cohort-study-using-linked-administrative-data
#13
Deepa Singal, Marni Brownell, Dan Chateau, Chelsea Ruth, Laurence Y Katz
INTRODUCTION: Antidepressants are commonly prescribed during pregnancy; however, there are inconsistent data on the safety of these medications during the prenatal period. To address this gap, this study will investigate short-term and long-term neurodevelopmental, physical and mental health, and educational outcomes of children who have been exposed to selective serotonin reuptake inhibitors (SSRIs) or selective serotonin norepinephrine reuptake inhibitors (SNRIs) and/or maternal depression during pregnancy...
November 29, 2016: BMJ Open
https://www.readbyqxmd.com/read/27896246/quantitative-fluorescent-polymerase-chain-reaction-for-rapid-prenatal-diagnosis-of-fetal-aneuploidies-in-chorionic-villus-sampling-in-a-single-institution
#14
You Jung Shin, Jin Hoon Chung, Do Jin Kim, Hyun Mee Ryu, Moon Young Kim, Jung Yeol Han, June Seek Choi
OBJECTIVE: To validate quantitative fluorescent polymerase chain reaction (QF-PCR) via chorionic villus sampling (CVS) for the diagnosis of fetal aneuploidies. METHODS: We retrospectively reviewed the medical records of consecutive pregnant women who had undergone CVS at Cheil General Hospital between December 2009 and June 2014. Only cases with reported QF-PCR before long-term culture (LTC) for conventional cytogenetic analysis were included, and the results of these two methods were compared...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27883060/environmental-intervention-as-a-therapy-for-adverse-programming-by-ancestral-stress
#15
J Keiko McCreary, Zachary T Erickson, YongXin Hao, Yaroslav Ilnytskyy, Igor Kovalchuk, Gerlinde A S Metz
Ancestral stress can program stress sensitivity and health trajectories across multiple generations. While ancestral stress is uncontrollable to the filial generations, it is critical to identify therapies that overcome transgenerational programming. Here we report that prenatal stress in rats generates a transgenerationally heritable endocrine and epigenetic footprint and elevated stress sensitivity which can be alleviated by beneficial experiences in later life. Ancestral stress led to downregulated glucocorticoid receptor and prefrontal cortex neuronal densities along with precocious development of anxiety-like behaviours...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27862072/views-of-american-ob-gyns-on-the-ethics-of-prenatal-whole-genome-sequencing
#16
Michelle J Bayefsky, Amina White, Paul Wakim, Sara Chandros Hull, David Wasserman, Stephanie Chen, Benjamin E Berkman
OBJECTIVE: Given public demand for genetic information, the potential to perform prenatal whole-genome sequencing (PWGS) non-invasively in the future, and decreasing costs of whole-genome sequencing, it is likely that OB/GYN practice will include PWGS. The goal of this project was to explore OB/GYNs' views on the ethical issues surrounding PWGS and their preparedness for counseling patients on its use. METHODS: A national survey was administered to 2500 members of American Congress of Obstetricians and Gynecologists...
December 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27844025/prenatal-deletion-of-dna-methyltransferase-1-in-neural-stem-cells-impairs-neurogenesis-and-causes-anxiety-like-behavior-in-adulthood
#17
Hirofumi Noguchi, Ayaka Kimura, Naoya Murao, Masakazu Namihira, Kinichi Nakashima
Despite recent advances in our understanding of epigenetic regulation of central nervous system development, little is known regarding the effects of epigenetic dysregulation on neurogenesis and brain function in adulthood. In the present study, we show that prenatal deletion of DNA methyltransferase 1 (Dnmt1) in neural stem cells results in impaired neurogenesis as well as increases in inflammatory features (e.g., elevated glial fibrillary acidic protein [GFAP] expression in astrocytes and increased numbers of microglia) in the adult mouse brain...
2016: Neurogenesis (Austin, Tex.)
https://www.readbyqxmd.com/read/27837574/there-is-no-safe-threshold-for-lead-exposure-%C3%AE-literature-review
#18
Th Vorvolakos, S Arseniou, M Samakouri
: Lead was one of the most dangerous environmental toxic substances for a long time in western countries, and this is still the case for many places on earth today. Its neurotoxic potential is highly significant but its secure blood level concentration remains unknown. The aim of this study was to approach the above issue from the perspective of social psychiatry. A systematic search was made of Dialog and Datastar interfaces for data regarding the neuropsychiatric complications of direct or chronic exposure to lead, and a review of the relevant literature was conducted using the databases Medline, Embase, CAB Global Health and Cochrane...
July 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/27835662/marijuana-use-is-associated-with-behavioral-approach-and-depressive-symptoms-in-adolescents-and-emerging-adults
#19
Natasha E Wright, Danny Scerpella, Krista M Lisdahl
BACKGROUND: Repeated CB1 binding due to THC results in downregulation of the endocannabinoid system in cortex and limbic regions, perhaps disrupting frontolimbic functioning. This is particularly a concern in young adults who are still undergoing neurodevelopment in frontal and limbic regions. Such disruptions may be linked to increased depressive symptoms, anxiety symptoms, and executive dysfunction, and decreased behavioral approach. OBJECTIVES: Here we examine the influence of young adult marijuana use on anxiety, depressive symptoms, behavioral approach, and executive dysfunction...
2016: PloS One
https://www.readbyqxmd.com/read/27818729/maternal-nicotine-exposure-during-late-gestation-and-lactation-increases-anxiety-like-and-impulsive-decision-making-behavior-in-adolescent-offspring-of-rat
#20
Hyunchan Lee, Sooyeon Chung, Jihyun Noh
Prenatal nicotine exposure over an entire pregnancy has been associated with an increased prevalence of hyperactivity, anxiety-like behavior and depression-like behavior in mature rats. However, the effects of maternal nicotine exposure in late gestation and lactation on the psychology and behavior of adolescent rat offspring are unclear. Thus, we investigated the effect of nicotine exposure during late gestation and lactation on anxiety-like and impulsive decision-making behavior in adolescent offspring of rat...
October 2016: Toxicological Research
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