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Prenatal anxiety

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https://www.readbyqxmd.com/read/28529444/childbirth-pain-attachment-orientations-and-romantic-partner-support-during-labor-and-delivery
#1
Carol L Wilson, Jeffry A Simpson
Attachment anxiety is associated with greater perceived physical pain, whereas social support is associated with lower pain perceptions. Few studies, however, have examined the joint effects of attachment and support on acute physical pain in a dyadic context. In this study, first-time expectant mothers (N=140) and their male partners completed romantic attachment measures (prenatally) and postnatal assessments of women's pain and men's emotional support during labor and delivery. More securely attached women benefited from emotional support in terms of reduced pain, more avoidantly attached women reported greater pain when given more support, and more anxiously attached women reported greater pain, regardless of their partner's support...
December 2016: Personal Relationships
https://www.readbyqxmd.com/read/28511978/behavioural-outcomes-of-adult-female-offspring-following-maternal-stress-and-perinatal-fluoxetine-exposure
#2
Veronika Kiryanova, Sara J Meunier, Richard H Dyck
Depression, anxiety, and stress are common in pregnant women. One of the primary pharmacological treatments for anxiety and depression is the antidepressant fluoxetine (Flx). Maternal stress, depression, and Flx exposure are known to effect neurodevelopment of the offspring, however, their combined effects have been scarcely studied, especially in female offspring. The present study investigated the combined effects of maternal stress during pregnancy and perinatal exposure to Flx on the behaviour of female mice as adults...
May 13, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28511050/maternal-distress-in-late-pregnancy-alters-obstetric-outcomes-and-the-expression-of-genes-important-for-placental-glucocorticoid-signalling
#3
Katie L Togher, Eimear Treacy, Gerard W O'Keeffe, Louise C Kenny
The experience of maternal distress in pregnancy is often linked with poorer obstetric outcomes for women as well as adverse outcomes for offspring. Alterations in placental glucocorticoid signalling and subsequent increased fetal exposure to cortisol have been suggested to underlie this relationship. In the current study, 121 pregnant women completed the Perceived Stress Scale, State Trait Anxiety Inventory and Edinburgh Postnatal Depression Scale in the third trimester of pregnancy. Placental samples were collected after delivery...
May 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28501681/postnatal-paternal-involvement-and-maternal-emotional-disturbances-the-effect-of-maternal-employment-status
#4
Wan-Chien Lin, Shin-Yow Chang, Yi-Ting Chen, Hsin-Chien Lee, Yi-Hua Chen
BACKGROUND: Recently, studies have begun emphasizing paternal involvement during the perinatal period and its impact on maternal health. However, most studies have assessed maternal perception and focused on adolescents or minority groups in Western countries. Therefore, the current study investigated the association between paternal involvement and maternal postnatal depression and anxiety, along with the effects of maternal job status in the Asian society of Taiwan. METHODS: This study recruited pregnant women in the first trimester of pregnancy as well as their partners on prenatal visits from July 2011 to September 2013 at four selected hospitals in metropolitan areas of Taipei, Taiwan...
May 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28482901/prenatal-listening-to-songs-composed-for-pregnancy-and-symptoms-of-anxiety-and-depression-a-pilot-study
#5
Chineze Nwebube, Vivette Glover, Lauren Stewart
BACKGROUND: Prenatal anxiety and depression are distressing for the expectant mother and can have adverse effects on her fetus and subsequently, her child. This study aimed to determine whether listening to specially composed songs would be an effective intervention for reducing symptoms of prenatal anxiety and depression. METHODS: Pregnant women were recruited online and randomly assigned to one of two groups: the music group (daily listening to specially composed songs) or control group (daily relaxation) for 12 weeks each...
May 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28480579/longitudinal-epigenetic-predictors-of-amygdala-hippocampus-volume-ratio
#6
Esther Walton, Charlotte A M Cecil, Matthew Suderman, Jingyu Liu, Jessica A Turner, Vince Calhoun, Stefan Ehrlich, Caroline L Relton, Edward D Barker
BACKGROUND: The ratio between amygdala:hippocampal (AH) volume has been associated with multiple psychiatric problems, including anxiety and aggression. Yet, little is known about its biological underpinnings. Here, we used a methylome-wide approach to test (a) whether DNA methylation in early life (birth, age 7) prospectively associates with total AH volume ratio in early adulthood, and (b) whether significant DNA methylation markers are influenced by prenatal risk factors. METHODS: Analyses were based on a subsample (n = 109 males) from the Avon Longitudinal Study of Parents and Children, which included measures of prenatal risk, DNA methylation (Infinium Illumina 450k), T1-weighted brain scans and psychopathology in early adulthood (age 18-21)...
May 8, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28458069/postnatal-development-and-behavior-effects-of-in-utero-exposure-of-rats-to-radiofrequency-waves-emitted-from-conventional-wifi-devices
#7
Haifa Othman, Mohamed Ammari, Kaïs Rtibi, Noura Bensaid, Mohsen Sakly, Hafedh Abdelmelek
The present work investigated the effects of prenatal exposure to radiofrequency waves of conventional WiFi devices on postnatal development and behavior of rat offspring. Ten Wistar albino pregnant rats were randomly assigned to two groups (n=5). The experimental group was exposed to a 2.45GHz WiFi signal for 2h a day throughout gestation period. Control females were subjected to the same conditions as treated group without applying WiFi radiations. After delivery, the offspring was tested for physical and neurodevelopment during its 17 postnatal days (PND), then for anxiety (PND 28) and motricity (PND 40-43), as well as for cerebral oxidative stress response and cholinesterase activity in brain and serum (PND 28 and 43)...
April 22, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28457883/low-dose-chronic-prenatal-alcohol-exposure-abolishes-the-pro-cognitive-effects-of-angiotensin-iv
#8
Sara Fidalgo, Charlotte Skipper, Abigail Takyi, Aisling McIver, Theodoros Tsiligkaridis, Angela Quadir, Paul R Gard
Prenatal ethanol exposure (PAE) in humans results in a spectrum of disorders including deficits in learning and memory. Animal models to date have typically used high ethanol doses but have not identified the biochemical changes underlying the cognitive deficit. This study used treatment of mouse breeding harems with 5% ethanol via drinking water throughout pregnancy and lactation and explored the behavioural consequences in the progeny at 3-6 months of age using the open field test, novel object recognition test and elevated plus maze to measure anxiety and memory consolidation...
April 27, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28440861/findings-from-the-families-on-track-intervention-pilot-trial-for-children-with-fetal-alcohol-spectrum-disorders-and-their-families
#9
Christie L M Petrenko, Mary E Pandolfino, Luther K Robinson
BACKGROUND: Individuals with fetal alcohol spectrum disorders (FASD) are at high risk for costly, debilitating mental health problems and secondary conditions, such as school disruption, trouble with the law, and substance use. The study objective was to pilot a multi-component intervention designed to prevent secondary conditions in children with FASD and improve family adaptation. METHODS: Thirty children with FASD or prenatal alcohol exposure (PAE) (ages 4 to 8) and their primary caregivers were enrolled...
April 25, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28418941/prenatal-fluoxetine-modifies-the-behavioral-and-hormonal-responses-to-stress-in-male-mice-role-for-glucocorticoid-insensitivity
#10
Ronit Avitsur
Women with major depressive disorder during pregnancy often use selective serotonin reuptake inhibitors (SSRIs) antidepressants. These drugs readily cross the placental barrier and impact the developing fetal brain. Recently, we reported that prenatal fluoxetine (FLX), an SSRI antidepressant drug, altered corticosterone and behavioral responses to stress in female mouse offspring. The present study assessed the effects of prenatal FLX on these responses in males. The results showed that prenatal FLX significantly augmented the corticosterone response to acute stress in young prepubescent mice...
April 17, 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/28417515/do-maternal-depression-and-anxiety-influence-children-s-oral-health-related-quality-of-life
#11
Francine Dos Santos Costa, Marina Sousa Azevedo, Thiago Machado Ardenghi, Ricardo Tavares Pinheiro, Flávio Fernando Demarco, Marília Leão Goettems
OBJECTIVE: This study aimed to investigate the influence of depressive and anxiety symptoms in young mothers on their perception in relation to their children's oral health-related quality of life (COHRQoL). METHODS: This cross-sectional study was carried out in Pelotas, Southern Brazil, and it was nested in a cohort of adolescent mothers having their prenatal care in public health service, starting in 2008. When the children were aged 24-36 months, they and their mothers were interviewed and submitted to clinical examination by a trained team...
April 17, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28412607/effect-of-early-postnatal-exposure-to-valproate-on-neurobehavioral-development-and-regional-bdnf-expression-in-two-strains-of-mice
#12
Kevin G Bath, Tiare Pimentel
Valproate has been used for over 30years as a first-line treatment for epilepsy. In recent years, prenatal exposure to valproate has been associated with teratogenic effects, limiting its use in women that are pregnant or of childbearing age. However, despite its potential detrimental effects on development, valproate continues to be prescribed at high rates in pediatric populations in some countries. Animal models allow us to test hypotheses regarding the potential effects of postnatal valproate exposure on neurobehavioral development, as well as identify potential mechanisms mediating observed effects...
May 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28403801/iga-igm-responses-to-gram-negative-bacteria-are-not-associated-with-perinatal-depression-but-with-physio-somatic-symptoms-and-activation-of-the-tryptophan-catabolite-pathway-at-the-end-of-term-and-postnatal-anxiety
#13
Roomruangwong Chutima, Buranee Kanchanatawan, Sunee Sirivichayakul, George Anderson, André F Carvalho, Sebastien Duleu, Michel Geffard, Michael Maes
Evidence has implicated the translocation of commensal Gram-negative bacteria (Gram-B) due to leaky gut in the pathophysiology of depression and physio-somatic symptoms (e.g. fatigue, pain, irritable bowel syndrome, malaise, etc.). In addition, the leaky gut may contribute to immune-inflammatory activation and oxidative stress. This study investigated whether bacterial translocation is associated with perinatal depression and anxiety scores and with prenatal physio-somatic symptoms and immune-inflammatory biomarkers, including the tryptophan catabolite (TRYCAT) pathway...
April 7, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28402697/the-prenatal-distress-measure-adaptation-of-the-postpartum-distress-measure-for-a-prenatal-sample
#14
Niela M Hirsch, Randy Fingerhut, Kelly C Allison
BACKGROUND: Pregnancy is a significant transition period for women that can be markedly stressful. The presence of elevated depressed mood and anxiety during pregnancy places mothers, fetuses, and neonates at greater risk for developing biological and psychological difficulties. It appears that no general measures of distress currently exist that can be used to screen for both prenatal anxiety and mood. MATERIALS AND METHODS: This study explores the applicability of postpartum distress measure (PDM), a validated general distress postpartum screening tool, in a prenatal sample...
April 12, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28401538/women-s-attitude-towards-routine-hpa-screening-in-pregnancy
#15
Dian Winkelhorst, Rosanne M Loeff, Elske van den Akker-van Marle, Masja de Haas, Dick Oepkes
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a potentially life-threatening disease with excellent preventative treatment available for subsequent pregnancies. In order to prevent index cases, the effectiveness of a population-based screening program has been suggested repeatedly. Therefore, we aimed to evaluate women's attitude towards possible future human platelet antigen (HPA)-screening in pregnancy MATERIAL AND METHODS: We performed a cross-sectional questionnaire study amongst healthy pregnant women receiving prenatal care in one of seven participating midwifery practices...
April 12, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28397629/the-impact-of-life-stress-on-adult-depression-and-anxiety-is-dependent-on-gender-and-timing-of-exposure
#16
Carly E Herbison, Karina Allen, Monique Robinson, John Newnham, Craig Pennell
There is debate about the relative importance of timing of stressful events prenatally and over the life course and risk for subsequent depressive/anxious illness. The aim of this study was to examine the relative roles of prenatal stress and postnatal stress trajectories in predicting depression and anxiety in early adulthood in males and females. Exposure to life stress events was examined in the Western Australian Pregnancy Cohort (Raine) Study during pregnancy and ages 1, 2, 3, 5, 8, 10, 14, and 17 years...
April 11, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28393063/neuropsychological-and-psychiatric-outcomes-in-dextro-transposition-of-the-great-arteries-across-the-lifespan-a-state-of-the-art-review
#17
REVIEW
Leila Kasmi, Damien Bonnet, Michèle Montreuil, David Kalfa, Nikoletta Geronikola, David C Bellinger, Johanna Calderon
Advances in prenatal diagnosis, perioperative management, and postoperative care have dramatically increased the population of survivors of neonatal and infant heart surgery. The high survival rate of these patients into adulthood has exposed the alarming prevalence of long-term neuropsychological and psychiatric morbidities. Dextro-transposition of the great arteries (d-TGA) is one of the most extensively studied cyanotic congenital heart defect (CHD) with regard to neurodevelopmental outcomes. Landmark studies have described a common neurodevelopmental and behavioral phenotype associated with d-TGA...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28390224/maternal-anxiety-related-to-prenatal-diagnoses-of-fetal-anomalies-that-require-surgery
#18
Abigail B Wilpers, Holly Powell Kennedy, Diane Wall, Marjorie Funk, Mert Ozan Bahtiyar
OBJECTIVES: To investigate maternal anxiety in women with pregnancies complicated by fetal anomalies that require surgery. DESIGN: Prospective comparison pilot study. SETTING: A fetal care center in a Northeastern U.S. academic medical center. PARTICIPANTS: Women in their second or early third trimesters of pregnancy; 19 with pregnancies complicated by fetal anomalies and 25 without. METHODS: After ultrasonography, all participants completed the Spielberger State-Trait Anxiety Inventory and a sociodemographic questionnaire...
May 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28386370/modifications-of-anxiety-like-behavior-in-prenatally-stressed-male-offspring-with-imbalance-of-androgens
#19
Julia Fedotova, Viktoria Akulova, Svetlana Pivina, Jozef Dragasek, Martin Caprnda, Peter Kruzliak
Gonadal hormones have been well-known to affect brain regions known to be involved in the modulation of mood and affective-related behavior. Prenatal stress might alter hypothalamic-pituitary-gonadal axis, it could be a target for development of affective-related disorders in male offspring. The present study was designed to examine an anxiety-like behavior in the adult male offspring with low levels of endogenous androgens delivered from pregnant dams exposed to prenatal stress from gestation day 15 to gestation day 19...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28379837/tokophobia-fear-of-childbirth-prevalence-and-risk-factors
#20
Karin Demšar, Matija Svetina, Ivan Verdenik, Natasa Tul, Isaac Blickstein, Vislava Globevnik Velikonja
OBJECTIVE: To identify the prevalence of and to determine the risk factors for developing a fear of childbirth (tokophobia). METHODS: We evaluated 191 pregnant women during Parenting and Childbirth Classes. Participants were approached when attending Parenting and Childbirth Classes between June 2014 and September 2014 and were asked to complete several questionnaires related to depression (CES-D), anxiety (STAI X1 and X2), satisfaction with life (SWLS), delivery expectation/experience (W-DEQ), and specific fears...
April 5, 2017: Journal of Perinatal Medicine
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