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https://www.readbyqxmd.com/read/28318177/can-soluble-transferrin-receptor-be-used-in-diagnosing-iron-deficiency-anemia-and-assessing-iron-response-in-infants-with-moderate-acute-malnutrition
#1
Bahar Bu Yu Kkaragöz, Necat A Akgun, Ayse D Bulus, Sultan Durmus Aydogdu, Cengiz Bal
OBJECTIVE: To evaluate the efficacy of soluble transferrin receptor (sTfR) in diagnosing iron deficiency anemia (IDA) and evaluating iron response in infants with moderate acute malnutrition (MAM). POPULATION AND METHODS: Infants with hemoglobin (Hb) levels lower than threshold values for anemia for their ages and hypochromic/ microcytic anemia on peripheral smear were recruited. MAM was defined as weight/height z score < -2 to -3. Complete blood count (CBC), iron parameters and sTfR were compared among 41 infants with MAM and anemia (MA group), 32 infants with anemia without MAM (group A), and healthy controls (n= 30)...
April 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28298762/comparison-of-butorphanol-and-fentanyl-for-the-relief-of-postoperative-shivering-associated-with-spinal-anesthesia
#2
Venkata Sesha Sai Krishna Manne, Srinivasa Rao Gondi
AIM: The aim of this study was to compare fentanyl and butorphanol for the relief of postoperative shivering in spinal anesthesia. MATERIALS AND METHODS: A total of 100 American Society of Anesthesiologists physical status Class I and II patients aged 19-60 years belonging to both sexes who were posted for elective surgical procedures under spinal anesthesia were divided into two groups (fentanyl and butorphanol) and monitored intraoperatively for the occurrence of shivering and time taken to control shivering after administration of fentanyl and butorphanol drugs...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28292588/endoscopy-after-esophagectomy-safety-demonstrated-in-a-porcine-model
#3
Vignesh Raman, Karen L Moodie, Obinna O Ofoche, Larry R Kaiser, Cherie P Erkmen
BACKGROUND: Endoscopy is useful in assessing conduit ischemia and anastomotic leaks after esophagectomy but poses a theoretical threat of anastomotic disruption. We used a porcine model to evaluate the safety of endoscopy after esophagectomy. METHODS: We performed esophagectomies in 10 live pigs and performed endoscopy with progressive air insufflation and continuous intraluminal pressure monitoring. We stopped insufflation when the intraluminal pressure reached a plateau...
February 9, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28291458/wearable-pulse-oximetry-measurements-on-the-torso-arms-and-legs-a-proof-of-concept
#4
Marcus Kramer, Aaron Lobbestael, Emily Barten, John Eian, Gregory Rausch
For decades pulse oximeters designed for use on the head, hands, or feet have provided invaluable estimates of oxygen saturation to medical personal attending to combat casualties. However, traditional placement sites are not ideal for the relatively new paradigm of continuous battlefield telemonitoring. To assess the feasibility of oximetry on nontraditional body sites, 42 healthy volunteers were enrolled, consented, and underwent an industry standard induced-hypoxia study. During the study volunteers used prototype wearable oximeters, designed for the torso, arms, and legs...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28285858/high-resolution-profile-of-inorganic-aqueous-geochemistry-and-key-redox-zones-in-an-arsenic-bearing-aquifer-in-cambodia
#5
Laura A Richards, Daniel Magnone, Chansopheaktra Sovann, Chivuth Kong, Sebastian Uhlemann, Oliver Kuras, Bart E van Dongen, Christopher J Ballentine, David A Polya
Arsenic contamination of groundwaters in South and Southeast Asia is a major threat to public health. In order to better understand the geochemical controls on the mobility of arsenic in a heavily arsenic-affected aquifer in northern Kandal Province, Cambodia, key changes in inorganic aqueous geochemistry have been monitored at high vertical and lateral resolution along dominant groundwater flow paths along two distinct transects. The two transects are characterized by differing geochemical, hydrological and lithological conditions...
March 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28285382/impact-of-deep-sedation-on-the-electrophysiological-behavior-of-pulmonary-vein-and-non-pv-firing-during-catheter-ablation-for-atrial-fibrillation
#6
Ryohsuke Narui, Seiichiro Matsuo, Ryota Isogai, Kenichi Tokutake, Kenichi Yokoyama, Mika Kato, Keiichi Ito, Shin-Ichi Tanigawa, Seigo Yamashita, Michifumi Tokuda, Keiichi Inada, Kenri Shibayama, Satoru Miyanaga, Kenichi Sugimoto, Michihiro Yoshimura, Teiichi Yamane
PURPOSE: Catheter ablation for atrial fibrillation is performed with and without deep sedation, which could affect the arrhythmogenic activity during the procedure. We investigated the impact of sedation on electrophysiological properties in patients with AF who underwent catheter ablation. METHODS: This study consisted of 255 consecutive patients with atrial fibrillation (229 males, persistent: 105 patients) who underwent a single-catheter ablation procedure. The patients were divided into the following two groups according to the depth of sedation during the procedure: group M (mild sedation with flunitrazepam in 138 patients) and group D (deep sedation with propofol in 117 patients)...
March 11, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28285317/efficacy-of-intravenous-iron-sucrose-in-hemodialysis-patients-with-restless-legs-syndrome-rls-a-randomized-placebo-controlled-study
#7
Yinghui Deng, Jinglin Wu, Qiang Jia
BACKGROUND Restless legs syndrome (RLS) is a common disorder in hemodialysis (HD) patients that causes sleep disturbances and diminished quality of life. Because iron deficiency has been implicated in the pathogenesis of RLS, we sought to investigate the effects of intravenous (IV) iron sucrose on symptoms of RLS in HD patients. MATERIAL AND METHODS The study was a randomized, placebo-controlled study of 1000 mg iron sucrose versus normal saline as placebo. Patients were evaluated at baseline and 2 weeks after the last injection...
March 12, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28283852/short-term-general-anesthesia-for-retro-bulbar-block-in-ophthalmic-surgery-generates-no-significant-hypercapnia
#8
Werner Baulig, Monica Weber, Beatrice Beck-Schimmer, Oliver M Theusinger, Peter Biro
To assess the impact of short time hypnosis for retro-bulbar anesthesia on ventilation in patients undergoing ophthalmic surgery of the anterior eye chamber. In all patients, a combined continuous transcutaneous carbon dioxide tension (PtcCO2) and partial oxygen saturation (SpO2) measurement was applied in addition to routine monitoring. To enable unconscious application of retro-bulbar anesthesia, intravenous thiopental was given in one to multiple bolus doses. Transient breathing support included chin lift, Esmarch maneuver and manual hand-bag ventilation via face mask...
March 11, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28283707/evaluating-the-cartilage-adjacent-to-the-site-of-repair-surgery-with-glycosaminoglycan-specific-magnetic-resonance-imaging
#9
Ulrich Koller, Sebastian Apprich, Benjamin Schmitt, Reinhard Windhager, Siegfried Trattnig
PURPOSE: The glycosaminoglycan (GAG) chemical exchange saturation transfer (CEST) imaging method (gagCEST) makes it possible to assess and quantify the GAG concentration in human cartilage. This biochemical imaging technique facilitates detection of the loss of GAG in the course of osteoarthritis. The gagCEST technique was used to analyse the perilesional zone (PLZ) adjacent to repair tissue after cartilage repair surgery, to determine whether there are biochemical changes present in the sense of degeneration...
March 10, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28282946/ratiometric-dissolved-oxygen-sensors-based-on-ruthenium-complex-doped-with-silver-nanoparticles
#10
Zike Jiang, Xinsheng Yu, Shikui Zhai, Yingyan Hao
A ratiometric optical sensor has been developed with electrospinning processing method for dissolved oxygen measurement. The sensing film is fabricated by using silver nano-particles (Ag NPs) doped with tris(4,7-diphenyl-1,10-phenanthroline) ruthenium(II) dichloride complex (Ru(DPP)₃Cl₂) encapsulated in plasticized polymethyl methacrylate (PMMA). An insensitive 3-(2-benzothiazolyl)-7-(diethy lamino)-(6CI,7CI) (Coumarin6) is adopted as reference. The ratio of oxygenation is calculated at each image pixel of a 3CCD camera to quantify the oxygen concentration in aqueous environment...
March 9, 2017: Sensors
https://www.readbyqxmd.com/read/28280719/cerebral-tissue-oxygenation-during-immediate-neonatal-transition-and-resuscitation
#11
REVIEW
Gerhard Pichler, Georg M Schmölzer, Berndt Urlesberger
This article provides a review of cerebral tissue oxygenation during immediate transition after birth in human neonates. Recommended routine monitoring, especially if resuscitation is needed, during this period includes arterial oxygen saturation and heart rate measured by pulse oximetry and electrocardiogram. However, there is increasing interest to monitor in addition with near-infrared spectroscopy (NIRS) the oxygenation of the brain. There is a different pattern of increase between cerebral tissue oxygenation and arterial oxygen saturation during the immediate transition, with cerebral tissue oxygenation reaching a plateau faster than arterial oxygen saturation...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28279497/hyperoxia-at-what-level-of-spo2-is-a-patient-safe-a-study-in-mechanically-ventilated-icu-patients
#12
E M J Durlinger, A M E Spoelstra-de Man, B Smit, H J de Grooth, A R J Girbes, H M Oudemans-van Straaten, Y M Smulders
BACKGROUND: Concerns have been expressed regarding a possible association between arterial hyperoxia and adverse outcomes in critically ill patients. Oxygen status is commonly monitored noninvasively by peripheral saturation monitoring (SpO2). However, the risk of hyperoxia above specific SpO2 levels in critically ill patients is unknown. The purpose of this study was to determine a threshold value of SpO2 above which the prevalence of arterial hyperoxia distinctly increases. METHODS: This is a cross-sectional study in adult mechanically ventilated intensive care patients in a tertiary referral center...
March 2, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28278259/prognostic-value-of-cerebral-tissue-oxygen-saturation-during-neonatal-extracorporeal-membrane-oxygenation
#13
Marie-Philippine Clair, Jérôme Rambaud, Adrien Flahault, Romain Guedj, Julia Guilbert, Isabelle Guellec, Amélie Durandy, Maryne Demoulin, Sandrine Jean, Delphine Mitanchez, François Chalard, Chiara Sileo, Ricardo Carbajal, Sylvain Renolleau, Pierre-Louis Léger
OBJECTIVES: Extracorporeal membrane oxygenation support is indicated in severe and refractory respiratory or circulatory failures. Neurological complications are typically represented by acute ischemic or hemorrhagic lesions, which induce higher morbidity and mortality. The primary goal of this study was to assess the prognostic value of cerebral tissue oxygen saturation (StcO2) on mortality in neonates and young infants treated with ECMO. A secondary objective was to evaluate the association between StcO2 and the occurrence of cerebral lesions...
2017: PloS One
https://www.readbyqxmd.com/read/28275123/body-monitoring-with-photonic-textiles-a-reflective-heartbeat-sensor-based-on-polymer-optical-fibres
#14
Brit M Quandt, Fabian Braun, Damien Ferrario, René M Rossi, Anke Scheel-Sailer, Martin Wolf, Gian-Luca Bona, Rudolf Hufenus, Lukas J Scherer, Luciano F Boesel
Knowledge of an individual's skin condition is important for pressure ulcer prevention. Detecting early changes in skin through perfusion, oxygen saturation values, and pressure on tissue and subsequent therapeutic intervention could increase patients' quality of life drastically. However, most existing sensing options create additional risk of ulcer development due to further pressure on and chafing of the skin. Here, as a first component, we present a flexible, photonic textile-based sensor for the continuous monitoring of the heartbeat and blood flow...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28274235/multicenter-study-on-the-effectiveness-of-the-pre-epiglottic-baton-plate-for-airway-obstruction-and-feeding-problems-in-robin-sequence
#15
Christian F Poets, Christoph Maas, Wolfgang Buchenau, Joerg Arand, Anne Vierzig, Bert Braumann, Silvia Müller-Hagedorn
BACKGROUND: Treatment of Robin sequence is often either invasive or of unproven effectiveness. The pre-epiglottic baton plate (PEBP) is a well-studied alternative, yet is not widely applied internationally. We report on a prospective 3-center cohort study investigating this treatment. Based on an agreed protocol, parents of infants with Robin sequence referred to participating centers were offered enrollment, which involved taking a maxillary cast followed by endoscopy to fit the plate and sleep studies to monitor its effectiveness...
March 9, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28270997/in-vivo-imaging-of-hepatic-hemodynamics-and-light-scattering-property-during-ischemia-reperfusion-in-rats-based-on-spectrocolorimetry
#16
Sharmin Akter, Satoko Kawauchi, Shunichi Sato, Suefumi Aosasa, Junji Yamamoto, Izumi Nishidate
A red-green-blue camera-based imaging method is proposed for estimating spatial maps of concentrations of oxyhemoglobin (CHbO), deoxyhemoglobin (CHbR), total hemoglobin (CHbT), tissue oxygen saturation (StO2), and scattering power (b) in liver tissue. Hemodynamic responses to hepatic ischemia-reperfusion of in vivo rat liver tissues induced by portal triad occlusion were evaluated. Upon portal triad occlusion, this method yielded images of decreased CHbO, CHbT, StO2, and b, and increased CHbR followed by a progressive increase in CHbO and StO2 during reperfusion...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28270967/normalization-of-compression-induced-hemodynamics-in-patients-responding-to-neoadjuvant-chemotherapy-monitored-by-dynamic-tomographic-optical-breast-imaging-dtobi
#17
Amir Y Sajjadi, Steven J Isakoff, Bin Deng, Bhawana Singh, Christy M Wanyo, Qianqian Fang, Michelle C Specht, Lidia Schapira, Beverly Moy, Aditya Bardia, David A Boas, Stefan A Carp
We characterize novel breast cancer imaging biomarkers for monitoring neoadjuvant chemotherapy (NACT) and predicting outcome. Specifically, we recruited 30 patients for a pilot study in which NACT patients were imaged using dynamic tomographic optical breast imaging (DTOBI) to quantify the hemodynamic changes due to partial mammographic compression. DTOBI scans were obtained pre-treatment (referred to as day 0), as well as 7 and 30 days into therapy on female patients undergoing NACT. We present data for the 13 patients who participated in both day 0 and 7 measurements and had evaluable data, of which 7 also returned for day 30 measurements...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28270380/exacerbations-in-chronic-obstructive-pulmonary-disease-identification-and-prediction-using-a-digital-health-system
#18
Syed Ahmar Shah, Carmelo Velardo, Andrew Farmer, Lionel Tarassenko
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive, chronic respiratory disease with a significant socioeconomic burden. Exacerbations, the sudden and sustained worsening of symptoms, can lead to hospitalization and reduce quality of life. Major limitations of previous telemonitoring interventions for COPD include low compliance, lack of consensus on what constitutes an exacerbation, limited numbers of patients, and short monitoring periods. We developed a telemonitoring system based on a digital health platform that was used to collect data from the 1-year EDGE (Self Management and Support Programme) COPD clinical trial aiming at daily monitoring in a heterogeneous group of patients with moderate to severe COPD...
March 7, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28269567/a-wrist-worn-spo2-monitor-with-custom-finger-probe-for-motion-artifact-removal
#19
S P Preejith, Akshay S Ravindran, Rohan Hajare, Jayaraj Joseph, Mohanasankar Sivaprakasam
Continuous monitoring of blood oxygen saturation (SpO2) level and heart rate is critical in surgery, ICUs and patients suffering from Chronic Obstructive Pulmonary Diseases. Pulse oximeters which compute SpO2 using transmittance photoplethysmography (PPG), is widely accepted for continuous monitoring. Presence of motion artifacts in PPG signals is a major obstacle in the extraction of reliable cardiovascular parameters, in real time and continuous monitoring applications. In this paper, a wrist worn device with a custom finger probe with an integrated accelerometer to remove motion artifacts is presented...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269385/a-wearable-bluetooth-le-sensor-for-patient-monitoring-during-mri-scans
#20
Christian Vogt, Jonas Reber, Daniel Waltisberg, Lars Buthe, Josip Marjanovic, Niko Munzenrieder, Klaas P Pruessmann, Gerhard Troster
This paper presents a working prototype of a wearable patient monitoring device capable of recording the heart rate, blood oxygen saturation, surface temperature and humidity during an magnetic resonance imaging (MRI) experiment. The measured values are transmitted via Bluetooth low energy (LE) and displayed in real time on a smartphone on the outside of the MRI room. During 7 MRI image acquisitions of at least 1 min and a total duration of 25 min no Bluetooth data packets were lost. The raw measurements of the light intensity for the photoplethysmogram based heart rate measurement shows an increased noise floor by 50LSB (least significant bit) during the MRI operation, whereas the temperature and humidity readings are unaffected...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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