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Aga Khan University

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https://www.readbyqxmd.com/read/28303989/frequency-of-worsening-liver-function-in-severe-dengue-hepatitis-patients-receiving-paracetamol-a-retrospective-analysis-of-hospital-data
#1
Ahsan Ali Syed, Faisal Aslam, Haris Hakeem, Faraz Siddiqui, Noreen Nasir
OBJECTIVE: To determine the frequency of worsening liver function among hospital in-patients with severe dengue hepatitis receiving paracetamol. METHODS: This retrospective study was conducted at the Department of Medicine, Aga Khan University Hospital, Karachi, and comprised records of dengue patients with severe hepatitis who received paracetamol for control of fever between June 2007 and December 2014. Alanine aminotransferase at baseline and following paracetamol administration was noted, as well as dosage and duration of paracetamol, along with participants' demographic details...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28303982/twin-chorionicity-and-prospective-stillbirth-risk-experience-at-a-tertiary-care-hospital
#2
Shazia Masheer, Zaheena Islam, Dhanwanti Dileep, Shama Munim
OBJECTIVE: To determine the prospective risk of stillbirth, perinatal death and neonatal morbidities in twins. METHODS: This retrospective cohort study was conducted at the Aga Khan University Hospital, Karachi, and comprised cases of twin pregnancies from January 2001 to December 2012. . Cases of both monochorionic diamniotic and dichorionic diamniotic twin pregnancies were included. SPSS 19 was used for data analysis.. RESULTS: Of the 394 cases, 84(21...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28303978/fistulotomy-versus-fistulectomy-for-simple-fistula-in-ano-a-retrospective-cohort-study
#3
Ghulam Murtaza, Fareed Ahmed Shaikh, Tabish Chawla, Batool Urooj Rajput, Noman Shahzad, Sumaiya Ansari
OBJECTIVE: To compare fistulotomy with fistulectomy for wound healing, duration of surgery, post-operative pain, incontinence and recurrence in patients with fistula in ano. METHODS: This retrospective cohort study was conducted at the Aga Khan University Hospital, Karachi, and comprised data of adults who had undergone fistulotomy/fistulectomy for simple fistula in ano from January 2007 to August 2012. Data collection was done in August 2013 using questionnaire and telephonic interviews...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28217723/cancer-nurses-in-africa-finding-their-footing
#4
EDITORIAL
David Makumi
David Makumi is an award-winning cancer control leader. The US Oncology Nursing Society. (ONS) awarded him the prestigious Distinguished Award for contribution to cancer care in 2011. The following year, the International Society of Nurses in Cancer Care presented him with the Past President Award for his work in designing low-cost models of increasing access to breast cancer screening. David is the East Africa Regional Cancer Programs Manager for the Aga Khan University Hospital. He has been involved in cancer advocacy on policy and legislation for over 10 years...
January 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28217048/radiofrequency-ablation-of-hepatocellular-carcinomas-a-new-spectrum-of-anesthetic-experience-at-a-tertiary-care-hospital-in-pakistan
#5
Faisal Shamim, Ali Asghar, Saman Tauheed, Muhammad Yahya
BACKGROUND: Radiofrequency ablation (RFA) is a minimally invasive technique of tumor destruction for patients with hepatic cancer who are not candidates for conventional therapy. The therapy required general anesthesia (GA) or sedation to ensure patient safety and comfort. The study is aimed to report and evaluate factors that influenced the periprocedural anesthetic management, drugs used, and complications during and immediately after RFA procedure for hepatocellular carcinoma. METHODS: For this retrospective study, we included 46 patients who underwent percutaneous RFA under GA or conscious sedation from January 2010 to June 2013 in Aga Khan University Hospital, Pakistan...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28215056/an-analysis-of-blood-utilization-for-stem-cell-transplant-patients-in-a-tertiary-care-hospital
#6
Natasha Ali
Background and Objective: Haematopoietic stem cell transplant is a potentially curative treatment option in various benign and malignant haematological diseases. Patients undergoing stem cell transplant procedure require blood transfusion on a daily basis. Currently, there is paucity of data from developing countries on transfusion practices. This audit was undertaken to determine the consumption of packed red blood cells (PRBCs) transfusion in the bone marrow transplant unit of the Aga Khan University Hospital...
February 28, 2017: International Journal of Stem Cells
https://www.readbyqxmd.com/read/28179699/referral-pattern-of-emergencies-in-obstetrics-implications-for-defining-scope-of-services-and-policy
#7
Rahat Najam Qureshi, Rozina Sikandar, Zahra Hoodbhoy, Raffat Bano, Nigar Jabeen
OBJECTIVE: To analyse referral pattern of high-risk obstetric cases from secondary to tertiary care hospitals and to assess their maternal and neonatal outcomes. METHODS: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised all referred obstetric cases from secondary-level hospitals to tertiary-level care within and outside the Hospital between January 2011 and December 2014. Day and time of referral, reason for referral as well as maternal and neonatal outcomes were collected...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28179697/antenatal-renal-pelvic-dilatation-and-foetal-outcomes-review-of-cases-from-a-tertiary-care-center-in-karachi-pakistan
#8
Ruqiya Afroz, Shafia Shakoor, Muhammad Sohail Salat, Shama Munim
OBJECTIVE: To determine the incidence of antenatal renal pelvic dilatation to evaluate antenatal resolution/ progression and post-natal outcome. METHODS: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised data of all women found with renal pelvic dilatation in antenatal scans between January 2011 and December 2013. A cut-off of 5mm was used to diagnose renal pelvic dilatation. Renal pelvic dilatation was categorised into three groups: mild (5-6mm in second trimester and 5-9mm in third trimester), moderate (7-10mm in second trimester and 10-15 in third) and severe (more than 10mm in second trimester and more than 15mm in third trimester)...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28179690/association-of-vitamin-d-deficiency-with-poor-glycaemic-control-in-diabetic-patients
#9
Khalida Iqbal, Najmul Islam, Naseema Mehboobali, Ali Asghar, Mohammad Perwaiz Iqbal
OBJECTIVE: An association between serum levels of vitamin D and glycaemic control in type-2 diabetes mellitus (DM) patients has been reported in some of the studies carried out in the West. However, there are no reports on this relationship in Pakistani diabetic patients. The aim of this study was to ascertain whether vitamin D levels have any influence on glycaemic control in Pakistani patients with type-2 DM. METHODS: In a cross-sectional survey, relationship between serum levels of 25-hydroxy vitamin D (25(OH)D) and glycated haemoglobin (HbA1C) was examined in 141 type-2 diabetic patients including 102 males and 39 females; age range 22 to 70 years, visiting the Aga Khan University Hospital during July 2013-April 2014...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28161918/bowled-over-by-cricket-impact-of-tape-ball-injuries-on-the-eyes
#10
Salman Naveed Sadiq, Azam Ali, Bushra Usmani, Khabir Ahmad
PURPOSE: The aim of this study was to describe the type and severity of tape-ball cricket-related eye injuries seen at a tertiary care hospital. DESIGN: A descriptive case series. METHODS: This study included all cases of tape-ball cricket-related eye injuries presenting to the Section of Ophthalmology, Aga Khan University Hospital, Karachi, from January 2014 to January 2015. RESULTS: A total of 20 patients with tape-ball cricket-related eye injuries were treated during this period...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28156592/symptom-burden-and-distress-in-patients-with-cancer-in-africa
#11
(no author information available yet)
255 Background: Cancer has become a significant public health problem in Africa but still most diagnoses are made late, Sitas et al (2006). The need for palliative care is significant due to the late contact with health care providers and the many symptoms they present with. No study has been undertaken to assess symptomatology for these patients in Africa. OBJECTIVE: To study the prevalence of symptoms in patients with cancer in an African setting. METHODS: Symptom studies from records of patients with cancer referred to the Palliative Care Services at the Aga Khan University Hospital, Nairobi in 6 months...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28138197/hookworm-infestation-as-a-cause-of-melena-and-severe-anaemia-in-farmer
#12
Marvi Tariq, Syeda Maria Muzammil, Fareed Ahmed Shaikh, K M Inam Pal
Hookworm infections remain a major cause of morbidity in the developing world. Prevalence is highest in agricultural areas, where use of waste water for irrigation and poor hygiene increases infection rates among farmers. Infections present with gastrointestinal symptoms and chronic anaemia, and there are usually no signs of overt blood loss. The following report describes a case of melena in a middle-aged farmer, where the diagnosis of hookworm infestation was delayed due to the unusual presentation. The patient underwent multiple blood transfusions before referral to the Aga Khan University Hospital (AKUH), Karachi and was managed conservatively with mebendazole at our hospital after exclusion of other possible causes of gastrointestinal bleeding...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138196/superior-septal-approach-versus-left-atrial-approach-for-mitral-valve-replacement-a-retrospective-cohort-study
#13
Tooba Ansar, Taimur Asif Ali, Saneeha Shahid, Saulat Hasnain Fatimi, Ghulam Murtaza
OBJECTIVE: To compare the outcomes of superior septal approach and left atrial approach for mitral valve replacement. METHODS: This retrospective cohort study was conducted at the Aga Khan University Hospital, Karachi, and comprised records of patients who had undergone isolated mitral valve replacement from May 2003 to April 2012. Cases were reviewed for the outcomes [primary: loss of normal sinus rhythm; secondary: complications, residual defect and mortality]...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138182/gestational-diabetes-mellitus-and-the-predisposing-factors
#14
Syeda Sadia Fatima, Rehana Rehman, Faiza Alam, Sarosh Madhani, Bushra Chaudhry, Taseer Ahmed Khan
OBJECTIVE: To evaluate the occurrence of gestational diabetes mellitus and its association with demographic and anthropometric variables in pregnant women. METHODS: This cross-sectional study was conducted at the Aga Khan University Hospital, Abbasi Shaheed Hospital and Memon Hospital in Karachi, from February 2014 to December 2015, and comprised pregnant women who were screened by 75-g 2-hour oral glucose tolerance test, (24-28 weeks of gestation) and classified as per the criteria of the International Association of Diabetes and Pregnancy Study Group...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28138174/parental-perception-and-childhood-obesity-contributors-to-incorrect-perception
#15
Hiba Ashraf, Nida Ilyas Shamsi, Ruhma Ashraf
OBJECTIVE: To determine parental recognition of their child's weight, and to identify the contributing reasons for incorrect perception. METHODS: This cross-sectional study was conducted from April to October 2010 at Aga Khan University Hospital, Karachi, and comprised parents of healthy children aged 5-14 years. An interviewer-based pre-tested questionnaire consisting of socio-demographic details, anthropometric measurements, and parental perception about their child's weight was administered...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28118824/factors-that-influence-advance-directives-completion-amongst-terminally-ill-patients-at-a-tertiary-hospital-in-kenya
#16
Stephen Omondi, John Weru, Asim Jamal Shaikh, Gerald Yonga
BACKGROUND: An advance directive (AD) is a written or verbal document that legally stipulates a person's health care preference while they are competent to make decisions for themselves and is used to guide decisions on life-sustaining treatment in the event that they become incapacitated. AD can take the form of a living will, a limitation of care document, a do-not-resuscitate order, or an appointment of a surrogate by durable power of attorney. The completion rate of AD varies from region to region, and it is influenced by multiple factors...
January 25, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28092107/rsv-associated-hospitalizations-in-children-in-karachi-pakistan-implications-for-vaccine-prevention-strategies
#17
Asad Ali, Mohammad Tahir Yousafzai, Rabbia Waris, Fatima Jafri, Fatima Aziz, Imran Naeem Abbasi, Anita Zaidi
Major progress is being made in vaccines against Respiratory Syncytial Virus (RSV), with multiple vaccine candidates currently in the clinical phase of development. Making an investment case for public sector financing of RSV vaccine will require estimation of burden, cost-effectiveness, and impact. The aim of this study is to determine the proportion, age distribution and clinical spectrum of RSV associated hospitalizations in children in Karachi, Pakistan. A three years prospective study was conducted at the Aga Khan University Hospital in Karachi, a city of 20 million in south Pakistan, from August 2009 to June 2012...
January 16, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28065963/complications-of-in-patient-cerebral-angiography-comparison-between-patients-with-and-without-sub-arachnoid-haemorrhage
#18
Yaseen Rauf, Usman Tariq Siddiqui, Gohar Javed
OBJECTIVE: To compare complications of cerebral angiography among patients with and without subarachnoid haemorrhage. METHODS: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised records of patients undergoing inpatient therapeutic and diagnostic cerebral angiographies from 2001 to 2010. The patients were divided into subarachnoid and non-subarachnoid haemorrhage groups. During the study period no modifications were made to the operational protocol and all patients were subjected to the same procedure and prophylactic care...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065945/dream-of-a-conducive-learning-environment-one-dreem-for-all-medical-students
#19
Rehana Rehman, Kulsoom Ghias, Syeda Sadia Fatima, Mehwish Hussain, Faiza Alam
OBJECTIVE: To compare students' response assessed by Dundee Ready Educational Environment Measure on the basis of the year of study, gender and pre-medical educational background. METHODS: This cross-sectional study was carried out at the Aga Khan University Medical College, Karachi, Pakistan, from June 2014 to March 2015, and comprised medical students. The average scores of Dundee Ready Educational Environment Measure scales and subscales were compared between gender and educational background...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28043630/effective-testing-for-pulmonary-tuberculosis-using-xpert-mtb-rif-assay-for-stool-specimens-in-immunocompetent-pakistani-children
#20
Zahra Hasan, Fehmina Arif, Sadia Shakoor, Aisha Mehnaz, Alnoor Akber, Akbar Kanji, Mussarat Ashraf, Rumina Hasan
OBJECTIVE/BACKGROUND: Childhood tuberculosis (TB) is largely a paucibacillary disease and difficult to diagnose. It is difficult to obtain a sputum or gastric aspirate (GA) sample, and patients are often undiagnosed and treated empirically. Stool is a noninvasive specimen not usually used for TB testing in Pakistan. We investigated the value of Xpert MTB/RIF to diagnose Mycobacterium tuberculosis (MTB) in children with pulmonary TB cases, by performing comparative testing of GA and stool samples...
December 2016: International Journal of Mycobacteriology
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