keyword
MENU ▼
Read by QxMD icon Read
search

Urinary stones

keyword
https://www.readbyqxmd.com/read/28642891/safety-tolerability-of-the-anti-semaphorin-4d-antibody-vx15-2503-in-a-randomized-phase-1-trial
#1
Christopher LaGanke, Lawrence Samkoff, Keith Edwards, Lily Jung Henson, Pavle Repovic, Sharon Lynch, Lael Stone, David Mattson, Aaron Galluzzi, Terrence L Fisher, Christine Reilly, Laurie A Winter, John E Leonard, Maurice Zauderer
OBJECTIVE: To evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of VX15/2503 in a randomized, single-dose, dose-escalation, double-blind, placebo-controlled study enrolling adult patients with MS. METHODS: Single IV doses of VX15/2503 or placebo were administered. Ten patients each were randomized (4:1 randomization ratio) into 5 ascending dose cohorts of 1, 3, 6, 10, or 20 mg/kg. Safety, immunogenicity, PK/PD, MRI, ECG, and lymphocyte subset levels were evaluated...
July 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28629039/time-dependent-subcellular-structure-injuries-induced-by-nano-micron-sized-calcium-oxalate-monohydrate-and-dihydrate-crystals
#2
Xin-Yuan Sun, Kai Yu, Jian-Ming Ouyang
Comparative studies were conducted to investigate the time effect of cell injury induced by nano-sized (50nm) and micron-sized (10μm) calcium oxalate monohydrate (COM) and dihydrate (COD) crystals in African green monkey renal epithelial (Vero) cells. The effects of nano-/micron-sized COM and COD exposure on Vero cells were investigated by detecting the cell viability, cell morphology, LDH release, reactive oxygen species, mitochondrial membrane potential, cell cycle, and cell apoptosis, as well as the intracellular and extracellular crystal distribution...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28627825/the-comparison-of-urinary-stones-between-she-minority-and-han-nationality-in-east-fujian-china
#3
Changming Liu, Liheng Lin, Huihong Chen, Qingping Xue, Mingxiong Sheng
BACKGROUND: The purpose of the study was to compare the incidence of urinary stones of She minority and Han nationality and analyze the composition of urinary stones. METHODS: The study was performed in 381 cases with 181 She minority and 200 Han nationality. The composition of stones was mainly analyzed by infrared absorption spectrum. The incidence of urinary stones at different ages, different gender and different parts was compared between She minority and Han nationality...
May 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28625699/influence-of-staff-infection-control-training-on-infection-related-quality-measures-in-us-nursing-homes
#4
Jasjit Kaur, Patricia W Stone, Jasmine L Travers, Catherine C Cohen, Carolyn T A Herzig
Health care-associated infections are a leading cause of morbidity and mortality in US nursing home residents. Ongoing training of nursing home staff is vital to the implementation of infection prevention and control processes. Our aim was to describe associations between methods, frequency, and timing of staff infection prevention and control training and infection-related quality measures. In this national survey of nursing homes, timing of staff infection prevention and control training was associated with reduced indwelling urinary catheter use...
June 15, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28623397/different-effects-of-%C3%AE-linolenic-acid-gla-supplementation-on-plasma-and-red-blood-cell-phospholipid-fatty-acid-composition-and-calcium-oxalate-kidney-stone-risk-factors-in-healthy-subjects-from-two-race-groups-with-different-risk-profiles-pose-questions-about
#5
Allen L Rodgers, Dalielah Jappie-Mahomed, Paul J van Jaarsveld
Fatty acid (FA) composition of phospholipids in plasma and red blood cells (RBC) can influence calciuria, oxaluria and renal stone formation. In this regard, the ratio of arachidonic acid (AA) and its precursor linoleic acid (LA) appears to be important. Administration of γ-linolenic acid (GLA) has been shown to increase the concentration of dihomo-gamma linoleic acid (DGLA) relative to AA indicating that it may attenuate biosynthesis of the latter. Such effects have not been investigated in race groups having difference stone occurrence rates...
June 16, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28621639/outcome-of-the-double-j-stent-placement-in-pediatric-kidney-transplant-a-single-center-experience
#6
Hakan Sözen, Onur Özen, Kibriya Fidan, Oğuz Söylemezoğlu, Aydın Dalgıç
OBJECTIVES: Double J stent placement at kidney transplant may reduce stenosis or leakage complication rates. However, placement may also increase risk for early urinary tract infection (ie, < 3 mo after transplant). In children, the usefulness of double J stent placement is not well defined. MATERIALS AND METHODS: We analyzed retrospective data from children who received transplants at the Gazi University Transplantation Center and Pediatric Nephrology (Ankara, Turkey) for outcomes related to double J stents...
June 16, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28618681/re-defining-the-rate-of-negative-ureteroscopy-in-the-general-population-treated-for-upper-tract-urinary-stone-disease
#7
David S Wang
No abstract text is available yet for this article.
July 2017: Journal of Urology
https://www.readbyqxmd.com/read/28608192/stone-technology-intracorporeal-lithotripters
#8
Kymora B Scotland, Tadeusz Kroczak, Kenneth T Pace, Ben H Chew
PURPOSE: Intracorporeal lithotripsy is becoming the most commonly used surgical method of stone treatment in Urology. The five major types of intracorporeal lithotripters are ultrasonic, ballistic, and combination lithotripters as well as laser and electrohydraulic lithotripters. The advantages and disadvantages of choosing each of these treatment modalities are reviewed. METHODS: Extensive review of literature was performed to identify the types of intracorporeal lithotripters...
June 12, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28605509/a-novel-homozygous-umod-mutation-reveals-gene-dosage-effects-on-uromodulin-processing-and-urinary-excretion
#9
Noel Edwards, Eric Olinger, Jennifer Adam, Michael Kelly, Guglielmo Schiano, Simon A Ramsbottom, Richard Sandford, Olivier Devuyst, John A Sayer
Heterozygous mutations in UMOD encoding the urinary protein uromodulin are the most common genetic cause of autosomal dominant tubulointerstitial kidney disease (ADTKD). We describe the exceptional case of a patient from a consanguineous family carrying a novel homozygous UMOD mutation (p.C120Y) affecting a conserved cysteine residue within the EGF-like domain III of uromodulin. Comparison of heterozygote and homozygote mutation carriers revealed a gene dosage effect with unprecedented low levels of uromodulin and aberrant uromodulin fragments in the urine of the homozygote proband...
June 10, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28599030/pediatric-nephrolithiasis-a-review
#10
Tayaba Miah, Deepak Kamat
The incidence of pediatric nephrolithiasis is on the rise. The composition of kidney stones in children is different than in adults, as most stones in children have a composition of calcium oxalate and calcium phosphate mixed with a small amount of uric acid. The symptoms of pediatric nephrolithiasis are nonspecific. Computed tomography (CT) is the gold standard for diagnosis; however, because of radiation exposure associated with a CT scan, ultrasonography is also an accepted modality for the diagnosis. Extensive metabolic evaluation is important to rule out an underlying metabolic disorder...
June 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28597355/minimal-device-encrustation-on-vesair-intravesical-balloons-in-the-treatment-of-stress-urinary-incontinence-analysis-of-balloons-removed-from-women-in-the-solect-trial
#11
Gommert A van Koeveringe, Stefan De Wachter, Jack M Zuckerman, Giovanni Tommaselli, Michel J de Wildt, Karel C M Everaert, Dirk P J Michielsen, Jean-Jacques Wyndaele
INTRODUCTION: Encrustation of urinary biomaterials is common; however, the incidence of surface deposition on the Vesair(®) intravesical pressure-attenuation balloon has not been previously reported. The purpose of this analysis is to determine the incidence and potential risk factors for encrustation of the Vesair intravesical balloon. METHODS: The SOLECT trial is a prospective randomized controlled trial conducted at several European centers to evaluate the safety and efficacy of the Vesair balloon for the treatment of female stress urinary incontinence (SUI)...
June 9, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28595936/the-peak-site-of-stone-distribution-in-the-upper-ureter-is-unlikely-the-ureteropelvic-junction-ct-analysis-of-stone-lodging-site-with-respect-to-a-newly-identified-area-of-constriction
#12
Minobu Kamo, Taiki Nozaki, Jay Starkey, Saya Horiuchi, Natsuka Muraishi, Kazunori Hattori, Keiichi Akita
OBJECTIVES: To investigate the relationship between the upper urinary stone distribution and the "crossing point"; an area of relative fixation within the upper ureter at approximately the level where the ureter crosses the gonadal vein. METHODS: We reviewed 298 consecutive patients presenting with acute renal colic, identified upper ureteral stones in computed tomography. For stones located at "renal pelvis and upper ureter", we measured the vertebral level of each renal pelvis, crossing point, and stone...
June 5, 2017: Urology
https://www.readbyqxmd.com/read/28592876/elongation-factor-tu-on-escherichia-coli-isolated-from-urine-of-kidney-stone-patients-promotes-calcium-oxalate-crystal-growth-and-aggregation
#13
Piyawan Amimanan, Ratree Tavichakorntrakool, Kedsarin Fong-Ngern, Pipat Sribenjalux, Aroonlug Lulitanond, Vitoon Prasongwatana, Chaisiri Wongkham, Patcharee Boonsiri, Jariya Umka Welbat, Visith Thongboonkerd
Escherichia coli is the most common bacterium isolated from urine and stone matrix of calcium oxalate (CaOx) stone formers. Whether it has pathogenic role(s) in kidney stone formation or is only entrapped inside the stone remains unclear. We thus evaluated differences between E. coli isolated from urine of patients with kidney stone (EUK) and that from patients with urinary tract infection (UTI) without stone (EUU). From 100 stone formers and 200 UTI patients, only four pairs of EUK/EUU isolates had identical antimicrobial susceptibility patterns...
June 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28589147/ultrasonography-is-not-inferior-to-fluoroscopy-to-guide-extracorporeal-shock-waves-during-treatment-of-renal-and-upper-ureteric-calculi-a-randomized-prospective-study
#14
Jeroen Van Besien, Pieter Uvin, Isabeau Hermie, Thomas Tailly, Luc Merckx
OBJECTIVE: To investigate whether the visualization modality (ultrasound or fluoroscopy) used during shockwave lithotripsy (SWL) affects the clinical outcome in those instances where both imaging modalities are optional. METHODS: Between November 2014 and July 2016, 114 patients with radiopaque upper urinary tract calculi were randomly assigned to an ultrasound- or fluoroscopy-guided SWL group in a prospective, open-label, single-center study. A standardized SWL protocol was used...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28588843/bilateral-hydronephrosis-due-to-obstructive-ureteral-stone-associated-with-norovirus-gastroenteritis
#15
Fumihiro Ochi, Kenji Furuno, Pin Fee Chong, Junichiro Tezuka, Yumi Mizuno, Tomonobu Aoki, Eiichi Ishii
Recently, cases of urinary tract calculi causing hydronephrosis and postrenal renal failure associated with viral gastroenteritis were documented, yet few were related to norovirus. During norovirus gastroenteritis, observation of oliguria, aciduria, low FENa value, and elevation of blood or urinary uric acid level may necessitate clinical workout for nephrolithiasis.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28587918/ct-based-diagnosis-of-visceral-obesity-and-hepatic-steatosis-is-associated-with-low-urine-ph
#16
Nishant D Patel, Ryan D Ward, Juan Calle, Erick M Remer, Manoj Monga
PURPOSE: Uric acid nephrolithiasis is associated with elevated visceral fat area (VFA) in kidney stone formers (KSF). Hepatic steatosis has also been linked to visceral obesity and nephrolithiasis. We evaluated the association of NCCT-based diagnosis of visceral obesity and hepatic steatosis with 24-hour urine parameters and stone composition in KSF. MATERIAL AND METHODS: 98 KSF were included who had CT imaging and 24-hour urine studies. For each patient, a single CT axial area measurement was obtained for visceral fat area (VFA)...
June 3, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28585833/energetic-basis-for-inhibition-of-calcium-phosphate-biomineralization-by-osteopontin
#17
Meng Li, Lijun Wang, Christine V Putnis
Calcium oxalate kidney stones form attached to Randall's plaques (RP), calcium phosphate (Ca-P) deposits on the renal papillary surface. Osteopontin (OPN) suppresses crystal growth in the complex process of urinary stone formation, but the inhibitory role of active domains of OPN involved in the initial formation of the RPs attached to epithelial cells has yet to be clarified. Here we demonstrate the thermodynamic basis for how OPN sequences regulate the onset of Ca-P mineral formation on lipid rafts as a model membrane...
June 12, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28585182/lime-powder-treatment-reduces-urinary-excretion-of-total-protein-and-transferrin-but-increases-uromodulin-excretion-in-patients-with-urolithiasis
#18
Piyaratana Tosukhowong, Pimsuda Kulpradit, Sakdithep Chaiyarit, Wattanachai Ungjareonwattana, Nuttiya Kalpongnukul, Supoj Ratchanon, Visith Thongboonkerd
Our previous study has shown that lime powder (LP) had an inhibitory effect against calcium oxalate stone formation. However, the precise mechanisms underlying such beneficial effect remained unclear. Our present study thus aimed to address the effect of LP on excretory level and compositions of urinary proteins using a proteomics approach. From a total of 80 calcium oxalate stone formers recruited into our 2-year randomized clinical trial of LP effect, 10 patients with comparable age and clinical parameters were selected for this proteomic study...
June 5, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28583110/jack-stone-in-the-bladder-case-report-of-a-rare-entity
#19
Duminda Subasinghe, Serozsha Goonewardena, Vickneswaran Kathiragamathamby
BACKGROUND: Jackstone is a bladder stone that has a similar appearance to toy jacks. However review of the English language medical literature revealed only a few previous reports of jackstone calculus. CASE PRESENTATION: We report a case in which a large jackstone calculus was incidentally detected during the evaluation of 67 year old male presenting with lower urinary tract symptoms. X-Ray kidney, ureter, bladder showed a large irregular shaped radio-opaque shadow in the pelvic region...
June 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28579066/renal-transplantation-using-stone-bearing-deceased-donor-kidneys-experience-of-a-transplant-center-in-china
#20
Chuan-Bao Chen, Liang Zhao, Ming Han, Xiao-Ping Wang, Jian Zhou, Xiao-Peng Yuan, Chang-Xi Wang
OBJECTIVE: To evaluate the outcomes of transplantation of deceased donor stone-bearing kidneys. METHODS: A total of 32 patients who received renal transplantation at our center from July 2011 to June 2016 were included. Eight recipients received kidneys with incidental renal stone(s) (stone group). Twenty-four recipients received kidneys without renal stones (non-stone group). The transplantation outcomes of the 2 groups were compared. RESULTS: There was 1 case of postoperative urinary tract infection in the stone group, and 2 cases in the non-stone group...
June 1, 2017: Urology
keyword
keyword
59635
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"