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https://www.readbyqxmd.com/read/28727383/outcomes-of-miniaturized-percutaneous-nephrolitotomy-in-infants-single-centre-experience
#1
Eyyup Sabri Pelit, Bülent Kati, Cengiz Çanakci, Süleyman Sağir, Halil Çiftçi
OBJECTIVES: The present study was aim to evaluate the safety and efficacy of Mini-PNL to treat kidney stones in patients aged <3 years. This is the one of the largest series in the literature in this age group of patients. MATERIAL AND METHODS: From May 2012 to April 2016, the medical records of 74 infant patients who underwent mini-PNL for renal stones were reviewed retrospectively. All infants were evaluated with the plain abdominal radiograph, urinary ultrasound, noncontrast computerized tomography and/or intravenous urogram...
July 20, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28726586/application-of-ureterorenoscope-and-flexible-ureterorenoscope-lithotripsy-in-removing-calculus-from-extracorporeal-living-donor-renal-graft-a-single-center-experience
#2
Chun-Hua Lin, Zuo-Fu Zhang, Jiahui Wang, Lu-Xin Yu, Wen-Ting Wang, Lei Shi, Xiang-Nan Lin
Here, we reported our clinical application of ureterorenoscope (URS) and flexible URS lithotripsy in stone removal on 10 cases of excised living donor kidney graft. After the extraction of donor kidney by retroperitoneal laparoscopy, the donor graft was perfused with 4 °C HCA solution. Calculus between 2-4 mm were removed intact with lithotomy forceps under direct vision of URS. Larger calculi of >4 mm were fractured with flexible URS combining holmium laser lithotripsy. Fragments of the calculus were extracted with basket extractor and lithotomy forceps...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28725602/transrectal-ultrasound-guided-extraction-of-impacted-prostatic-urethral-calculi-a-simple-alternative-to-endoscopy
#3
Gregory Amend, Jason Gandhi, Noel L Smith, Steven J Weissbart, David A Schulsinger, Gargi Joshi, Sardar Ali Khan
Urethral stones can become impacted in the posterior urethra, typically presenting with varying degrees of acute urinary retention and lower urinary tract symptoms. These are traditionally treated in the inpatient setting, with external urethrotomy or endoscopic push-back of the calculus into the urinary bladder followed by cystolitholapaxy or cystolithotripsy. However, these methods are invasive, involve general anesthesia, and require radiation. In this report, we describe a simple, minimally invasive, and safe alternative technique to visualize and remove impacted prostatic urethral stones under the real-time guidance of transrectal ultrasonography (TRUS)...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28723230/retrograde-endourological-management-of-upper-urinary-tract-abnormalities-in-patients-with-ileal-conduit-urinary-diversion-a-dual-center-experience
#4
Louise Olson, Hywel Satherley, Paul Cleaveland, Bachar Zelhof, Max Mokete, Donald Neilson, Shalom Srirangam
INTRODUCTION: Patients with ileal conduit urinary diversions are at an increased risk of long-term upper urinary tract (UUT) complications, including anastomotic strictures, infections, and urolithiasis. The reconstructed urinary system poses challenges for endoscopic manipulation. We present and describe our dual-center experience in performing retrograde ureteroscopy to treat or diagnose UUT abnormalities in patients with ileal conduit incontinent diversion. PATIENT AND METHODS: We performed a retrospective analysis of medical records for all patients with previous urinary diversion who underwent retrograde ureteroscopic procedures via the ileal loop in our institutions over a 9 year period (between June 2007 and August 2016)...
July 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28721286/open-stone-surgery-a-still-in-use-approach-for-complex-stone-burden
#5
Özer Ural Çakici, Kemal Ener, Murat Keske, Serkan Altinova, Abdullah Erdem Canda, Mustafa Aldemir, Arslan Ardicoglu
INTRODUCTION: Urinary stone disease is a major urological condition. Endourologic techniques have influenced the clinical approach and outcomes. Open surgery holds a historic importance in the management of most conditions. However, complex kidney stone burden may be amenable to successful results with open stone surgery. In this article, we report our eighteen cases of complex urinary stone disease who underwent open stone removal. MATERIAL AND METHODS: A total of 1701 patients have undergone surgical treatment for urinary stone disease in our clinic between July 2012 and July 2016, comprising eighteen patients who underwent open stone surgery...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28720371/genetic-risk-factors-for-idiopathic-urolithiasis-a-systematic-review-of-the-literature-and-causal-network-analysis
#6
REVIEW
Kazumi Taguchi, Takahiro Yasui, Dawn Schmautz Milliner, Bernd Hoppe, Thomas Chi
CONTEXT: Urolithiasis has a high prevalence and recurrence rate. Prevention is key to patient management, but risk stratification is challenging. In particular, genetic predisposition for urinary stones is not fully understood. OBJECTIVE: To review current evidence of potential causative genes for idiopathic urolithiasis and map their relationships to one another. This evidence is essential for future establishment of molecular targeted therapy. EVIDENCE ACQUISITION: A systematic literature review from 2007 to 2017 was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720369/metabolic-work-up-of-patients-with-urolithiasis-indications-and-diagnostic-algorithm
#7
REVIEW
Hans-Göran Tiselius, Michel Daudon, Kay Thomas, Christian Seitz
CONTEXT: The incidence of urinary tract stone disease is increasing and the risk of recurrent stone formation is high. Appropriate therapeutic procedures with the aim of counteracting the progress of stone formation are highly desirable. Metabolic work-up is considered essential as a base for optimal design and follow-up of effective recurrence prevention. OBJECTIVE: To scrutinize the current literature with regard to principles of metabolic work-up for this heterogeneous group of patients...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720368/a-critical-review-of-miniaturised-percutaneous-nephrolithotomy-is-smaller-better
#8
REVIEW
Silvia Proietti, Guido Giusti, Mahesh Desai, Arvind P Ganpule
CONTEXT: In an effort to reduce morbidity related to percutaneous nephrolithotomy (PCNL), some investigators have progressively introduced miniaturised approaches. The development of miniaturised nephroscopes facilitated widespread dissemination of these techniques and a significant expansion of the role of PCNL in endourology. OBJECTIVE: To discuss the different techniques comprising modern PCNL and identify the pros and cons of each of them. EVIDENCE ACQUISITION: Data for this review were identified through a search of PubMed, including studies published in the last 20 yr in core clinical journals in English...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720364/medical-expulsive-therapy-in-urolithiasis-a-review-of-the-quality-of-the-current-evidence
#9
REVIEW
Andreas Skolarikos, Khurshid R Ghani, Christian Seitz, Brandon Van Asseldonk, Matthew F Bultitude
CONTEXT: Medical expulsive therapy (MET) is widely used to promote spontaneous passage of urinary stones. However, there is conflicting evidence on the actual role of MET. OBJECTIVE: To evaluate the conformance of published randomized controlled trials (RCTs) on MET with the Consolidated Standards for Reporting Trials (CONSORT) criteria, and to clarify the current role of MET in management of urinary stones on the basis of our findings. EVIDENCE ACQUISITION: We carried out an electronic search of the Cochrane Library, PubMed, and Embase databases for RCTs on MET...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720363/burden-of-urolithiasis-trends-in-prevalence-treatments-and-costs
#10
REVIEW
Omer A Raheem, Yash S Khandwala, Roger L Sur, Khurshid R Ghani, John D Denstedt
CONTEXT: The recent evolution of management options for urolithiasis has presented a unique dilemma for the modern urologist. A comprehensive understanding of epidemiological trends along with current provider preferences in treating urinary stones would be beneficial. OBJECTIVE: To review trends in the prevalence, treatments, and costs of urolithiasis worldwide. EVIDENCE ACQUISITION: A literature review was performed using the MEDLINE database, the Cochrane Library Central search facility, Web of Science, and Google Scholar between 1986 and 2016...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720362/case-discussion-kidney-stone-in-a-patient-with-an-ileal-conduit
#11
Cesare Marco Scoffone, Cecilia Maria Cracco
Kidney stones in patients with ileal conduit and multiple sclerosis are secondary to postoperative anatomical changes and ascending urinary tract infections by urea-splitting bacteria. PNL is the preferred treatment option in patients with urinary diversion and infectious renal stones.
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28720357/clinical-case-discussion-kidney-stone-in-a-patient-with-an-ileal-conduit
#12
R Jeroen A van Moorselaar, Jakko A Nieuwenhuijzen
A patient underwent robot-assisted laparoscopic cystectomy with an ileal conduit urinary diversion. Percutaneous nephrolithotomy was performed for treatment of a kidney stone. Stone analysis revealed struvite.
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28719978/optimizing-rna-extraction-of-renal-papilla-biopsy-tissue-in-kidney-stone-formers-a-new-methodology-for-genomic-study
#13
Kazumi Taguchi, Manint Usawachintachit, Shuzo Hamamoto, Rei Unno, David T Tzou, Benjamin Sherer, Yongmei Wang, Atsushi Okada, Marshall Stoller, Takahiro Yasui, Thomas Chi
INTRODUCTION: Endoscopic tools have provided versatile examination and treatment for kidney stone procedures. Despite endourologists researching urinary stone disease using endoscopes to collect tissue, this tissue collection method is limited. Endoscopically removed tissues are small in size, restricting the types of genome-based examination possible. We investigated a new method of renal papilla biopsy and RNA extraction to establish a genomic research methodology for kidney stone disease...
July 18, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28718073/a-randomised-phase-ii-iii-study-to-evaluate-the-efficacy-and-safety-of-orally-administered-oxalobacter-formigenes-to-treat-primary-hyperoxaluria
#14
Dawn Milliner, Bernd Hoppe, Jaap Groothoff
Primary hyperoxaluria (PH) patients overproduce oxalate because of rare genetic errors in glyoxylate metabolism. Recurrent urolithiasis and/or progressive nephrocalcinosis are PH hallmarks and can lead to kidney damage, systemic oxalosis and death. Based on previous studies, we hypothesised that treatment with the oxalate-metabolizing bacterium Oxalobacter formigenes would mediate active elimination of oxalate from the plasma to the intestine of PH patients, thereby reducing urinary oxalate excretion (Uox)...
July 17, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28717544/is-it-safe-to-prescribe-ascorbic-acid-for-urinary-acidification-in-stone-forming-patients-with-alkaline-urine
#15
Yasser A Noureldin, Alexandrine da Silva, Nader Fahmy, Sero Andonian
OBJECTIVE: To study the effect of ascorbic acid (AA) supplementation on urinary pH, metabolic stone workup parameters, and development of de novo urolithiasis in stone-forming patients. MATERIAL AND METHODS: A retrospective review of the patients followed-up at a tertiary stone centre between September 2009 and October 2015 was performed. Patients with recurrent urolithiasis who received AA supplementation as a urinary acidifying agent were included in the study...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28717532/retrograde-intrarenal-surgery-for-renal-stones-part-1
#16
REVIEW
Ben Van Cleynenbreugel, Özcan Kılıç, Murat Akand
The main aim in the treatment of renal stones is to clearance of the stones completely with the least morbidity. Parallel to the improvements in technology during recent years, new flexible ureterorenoscopes and effective lithotripters such as holmium laser have been developed, thus retrograde intrarenal surgery (RIRS) has become an efficient and safe option in the management of urinary system stone disease with a gradually increasing popularity. Therewithal, innovations in auxiliary equipment such as guide-wires, ureteral access sheath and stone baskets have made this procedure more effective...
June 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28711958/systematic-assessment-of-urinary-hydroxy-oxo-glutarate-for-diagnosis-and-follow-up-of-primary-hyperoxaluria-type-iii
#17
Ada Ventzke, Markus Feldkötter, Andrew Wei, Jutta Becker, Bodo B Beck, Bernd Hoppe
BACKGROUND: There are currently three distinct autosomal recessive inherited types of primary hyperoxaluria (PH: PHI, PHII, and PHIII), all characterized by the endogenous overproduction of oxalate. The PH type is difficult to differentiate by clinical features alone. In addition to universal general characteristics to all hyperoxaluria subtypes, specific urinary metabolites can be detected: glycolate in PHI, L-glyceric acid in PHII, and hydroxy-oxo-glutarate (HOG) in PHIII. PHIII is considered to be the most benign form and is characterized by severe recurrent urolithiasis in early life, followed by clinical remission in many, but not all patients...
July 15, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28707190/novel-porcine-model-for-calcium-oxalate-stone-formation
#18
Brandon P Trojan, Sara J Trojan, Andrew Navetta, Bryce Staches, Bryan Sutton, Stephanie Filleur, Thomas Nelius
BACKGROUND: Mechanisms for calcium-based stone formation are not clearly delineated. Porcine are the most anatomically and physiologically congruent mammal to humans. Our objectives were to develop a cost-effective and easily reproducible porcine model for the study of calcium-based nephrolithiasis. METHODS: Crossbred male pigs (n = 16) were assigned randomly to one of the following treatments: (1) control; (2) ethylene glycol (EG) + vitamin D (VD); (3) EG + ammonium chloride (AC); (4) EG + gentamicin (G); (5) EG + Lasix; (6) EG + VD + AC; (7) EG + VD + G...
July 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28705575/can-a-simplified-12-hour-night-time-urine-collection-predict-urinary-stone-risk
#19
Bryan D Hinck, Vishnuvardhan Ganesan, Sarah Tarplin, John Asplin, Ignacio Granja, Juan Calle, Sri Sivalingam, Manoj Monga
OBJECTIVES: To determine if there is correlation between night time 12-hour and traditional 24-hour urine collection in regards to chemistry values and the super-saturations of calcium oxalate, calcium phosphate, and uric acid for the metabolic evaluation of nephrolithiasis. METHODS: 95 patients were prospectively enrolled from 2013-2015. Patients >18 years of age who presented to a tertiary stone clinic and who would normally be counseled for 24-hour urine collection were eligible for the study...
July 10, 2017: Urology
https://www.readbyqxmd.com/read/28704395/intraperitoneal-pyrophosphate-treatment-reduces-renal-calcifications-in-npt2a-null-mice
#20
Daniel Caballero, Yuwen Li, Jonathan Fetene, Julian Ponsetto, Alyssa Chen, Chuanlong Zhu, Demetrios T Braddock, Clemens Bergwitz
Mutations in the proximal tubular sodium-dependent phosphate co-transporters NPT2a and NPT2c have been reported in patients with renal stone disease and nephrocalcinosis, however the relative contribution of genotype, dietary calcium and phosphate, and modifiers of mineralization such as pyrophosphate (PPi) to the formation of renal mineral deposits is unclear. In the present study, we used Npt2a-/- mice to model the renal calcifications observed in these disorders. We observed elevated urinary excretion of PPi in Npt2a-/- mice when compared to WT mice...
2017: PloS One
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